Liliane Janete Grando

Federal University of Santa Catarina | UFSC · Departamento de Patologia

Lesion evaluation through photographs is a common clinical practice and its performance using computational tools is encouraged. Objective: To assess the reliability of the computer program SMART Monitoring (SM) in giving adequate lesion measurements through clinical photography. Materials and methods: A cross-sectional study was conducted with 28...

Purpose To investigate the impact of chemoradiation-induced hypopharyngeal mucositis on swallowing and its management, based on an integrative literature review. Research strategy Two researchers were responsible for the search and selection of articles, within the following databases: PubMed, Embase, Scopus, Science Direct, and Lilacs. Selection...

Purpose To investigate the impact of chemoradiation-induced hypopharyngeal mucositis on swallowing and its management, based on an integrative literature review. Research strategy Two researchers were responsible for the search and selection of articles, within the following databases: PubMed, Embase, Scopus, Science Direct, and Lilacs. Selection...

This study aimed to conduct a literature review about the influence of self-etching adhesives on the bond strength of restorative procedures for irradiated teeth. The search for articles was carried out on six databases (PubMed, Scopus, Web of Science, Embase, LILACS, Cochrane). Gray literature (Google Scholar) and reference lists of included studi...

Oral leukoplakia (OL) evaluation through photographs can be performed with the aid of Artificial Intelligence (AI). Supervised Machine Learning (SML) processes, which are based on labeling, are indicated to ensure a reliable computational mechanism of lesion identification. Thus, OL classification and demarcation within a photograph are crucial for...

Purpose This study assessed the prevalence of maxillofacial lesions in children, i.e., 0–9 years, and adolescents, i.e., 10–19 years, in a Brazilian Oral Pathology Service and compared results with available literature. Methods Clinical and histopathological records from January 2007 to August 2020 were analysed and a literature review investigati...

Aims: Mucormycosis is a rare and aggressive fungal infection with a high mortality rate because of its rapidly progressive and destructive nature. The oral cavity is often affected under opportunistic conditions. We report a 34-year-old woman diagnosed with acute myeloid leukemia complained of slight swelling on the right side of her face with too...

Carcinoma ex pleomorphic adenoma is a high-grade salivary gland cancer in which malignant transformation occurs in a previously benign pleomorphic adenoma. A 56-year-old woman attended the Hospital Dental Center presenting an exophytic sessile nodule on the hard palate. She had been diagnosed with a pleomorphic adenoma in this region a year prior....

Our aim is to report cases of osteoradionecrosis (ORN) of the jaws diagnosed and treated at a hospital dentistry service, emphasizing the distinct treatment modalities. A retrospective study included patients diagnosed with ORN and treated at a hospital dentistry service between 2008 and 2018. Patients’ charts and medical records were reviewed. Eig...

Carcinoma ex pleomorphic adenoma is an aggressive malignancy that arises in the epithelial and/or myoepithelial component of a pleomorphic adenoma. A 21-year-old female patient presented at a hospital dental center with a painless sessile nodule on the hard palate. An incisional biopsy was performed and the histopathologic result of a pleomorphic a...

O câncer de cavidade bucal, também conhecido como câncer de boca, é um tumor maligno que pode atingir estruturas anatômicas como lábios, língua, gengiva, bochecha e assoalho bucal. A parte posterior da língua, as amígdalas e o palato fibroso fazem parte da chamada região de orofaringe, e seus tumores têm comportamento diferente do que se vê no cânc...

Objectives : This study aimed to evaluate the accuracy of EstomatoNet/TelessaúdeRS, a telediagnosis service for oral diseases available to primary healthcare professionals in southern Brazil. Study Design : The sample of this multicenter cross-sectional study comprised 100 patients seen at the oral medicine outpatient clinic of three Brazilian Den...

RESUMO Objetivo: avaliar os aspectos clínico-epidemiológicos de pacientes com carcinoma epidermóide de boca e orofaringe atendidos em um Hospital Universitário. Métodos: Foi realizado um estudo epidemiológico descritivo, transversal e retrospectivo dos casos de carcinoma de boca diagnosticados no período de janeiro/2013 a dezembro/2018, por meio da...

Juvenile mandibular chronic osteomyelitis (JMCO) is a rare, idiopathic disease of chronic bone inflammation without suppuration, sinus tract formation, or sequestration. As the name suggests, this condition predominately affects children. The few cases of JMCO reported in the literature describe different treatments, and thus a standard therapy pro...

Intra-oral sebaceous adenoma (SA) is a rare benign tumor accounting for 0.1% of all salivary gland neoplasms consisting of sebaceous epithelium in a fibrous stroma. A 50-year-old female was referred by her dentist for treatment of an oral lesion in the right buccal mucosa and retromolar trigone. Clinically, a nodule asymptomatic was observed, 1.5 c...

A 32-year-old woman was referred by dermatology to conduct oral lesions because of the diagnosis of epidermal nevus with mucocutaneous involvement. Cutaneous lesions were characterized as erythematous to brownish macules and papules scattered on the face in the frontal, nasal, malar, cervical, auricular, and preauricular regions. In the oral examin...

Xanthomatous cells have lipid droplets in their cytoplasm. They may be associated with xanthomas that are cutaneous lesions of variable morphology, due to deposition of lipids in the skin. These deposits are inside histiocytes, which acquire a frothy appearance. They can be associated with disturbance of lipid metabolism, especially hyperlipemia an...

A 38-year-old man, user of illicit drugs, cannabis smoker, and alcoholic, presented an evolution of cutaneous, oral, and ophthalmologic lesions a few hours after the use of 5 to 8 tablets of amphetamine and alcohol. In 2011, a similar condition was reported after ingestion of cephalexin. Erythematous macules and papules were observed in the lower a...

Langerhans cell histiocytosis (LCH) is an inflammatory myeloid neoplastic proliferation with variable clinical behavior; the male:female ratio is 1.6:1.0. The pathogenesis of LCH is imperfectly understood. A newborn boy, 1 month old, had a small focal lesion with a papillomatous surface, was cured, and the tissue removed was granulomatous, friable,...

This report is about a 45-year-old man with acute myeloid leukemia (AML), treated with chemotherapy and allogeneic bone marrow transplant (allo-BMT) in 2010. After allo-BMT the patient developed chronic graft-versus-host disease (cGvHD) and was treated with a corticosteroid and immunosuppressants. In 2018, he presented with a whitish lesion with a...

Aims: To report two cases of onco-hematologic diseases diagnosed by oral biopsy and subsequent flow cytometry immunophenotyping. Presentation of Case: Case 1: A 36-year-old woman, HIV +, referred to the Hospital Dentistry Center presenting an extensive, ulcerated and painless lesion in the left maxilla involving teeth #24, #25, #26 and #27. A fine...

Aims: To report two cases of onco-hematologic diseases diagnosed by oral biopsy and subsequent flow cytometry immunophenotyping. Presentation of Case: Case 1: A 36-year-old woman, HIV +, referred to the Hospital Dentistry Center presenting an extensive, ulcerated and painless lesion in the left maxilla involving teeth #24, #25, #26 and #27. A fine...

Background: The cell-block technique is a cytological diagnostic method that decreases cellular dispersion; however, its usefulness regarding intraosseous lesions is underexplored. Therefore, this study aimed to assess the diagnostic usefulness of cell-block for cystic and cyst-like jaw lesions. Methods: Individuals with cystic or cyst-like jaw...

Objective To verify whether there are differences between populations of CD8+ and FoxP3+ T cells in lesions of oral lichen planus associated with hepatitis C virus chronic infection (OLP‐HCV) and lesions of idiopathic oral lichen planus (OLP‐I). Materials & Methods A case‐control study was performed using a convenience sample of 11 paraffin‐embedd...

Background Osteoradionecrosis of the jaw (ORNJ) is the most severe and complex sequel of head and neck radiotherapy (RT) because of the bone involved, it may cause pain, paresthesia, foul odor, fistulae with suppuration, need for extra oral communication and pathological fracture. We treated twenty lesions of ORNJ using low-level laser therapy (LLL...

Introduction: Reactive hyperplastic lesions develop in response to a chronic injury simulating an exuberant tissue repair response. They represent some of the most common oral lesions including inflammatory fibrous hyperplasia, oral pyogenic granuloma, giant cell fibroma, peripheral ossifying fibroma, and peripheral giant cell lesions. Objective:...

Poor description of oral lesions jeopardize the prioritization of appointments in Oral Medicine. The present study investigated whether the use of support tools changes the quality of descriptions focusing on health care prioritization. Two oral lesions (A and B) were described by 64 dental students and 48 dentists using three methods: (a) without...

Background and objective: radioiodine treatment (I¹³¹) used to treat thyroid carcinomas produces side effects (sialadenitis, xerostomia, dysphagia and caries susceptibility) reflecting in a poor patient quality of life. This study aimed to evaluate the effect of I¹³¹ on salivary function and possible oral impairment. Material and methods: Thirty-se...

Introduction: Osteonecrosis of the jaws can result either from radiation, used in radiotherapy for treatment of malignant tumors, or medications used for bone remodeling and anti-angiogenesis such as bisphosphonates. These conditions can be associated with triggering factors such as infection, trauma and decreased vascularity. The management of pa...

The idiopathic bone cavity (IBC) is an intraosseous pseudocyst devoid of epithelial lining. Clinically, IBCs of the jaw are asymptomatic and normally found in routine radiographic exams. Although the literature regarding the content of IBCs is controversial, the final diagnosis is usually aided by the discovery of an empty cavity upon surgical expl...

Introduction: Proliferative verrucous leukoplakia is a multifocal and progressive lesion of the oral mucosa, with unknown etiology, and commonly resistant to all therapy attempts with frequent recurrences. It is characterized by a high rate of oral squamous cell carcinoma and verrucou carcinoma transformations. Objective: To analyze the studies...

Introduction: The aim of this article is to present a rare case of myiasis caused by Dermatobia hominis. Myiasis is a disease caused by invasion of tissues of animals and humans by larval stages of dipterous (2-winged) flies. There are few reports of oral myiasis in the literature, mostly related to Cochliomyia hominivorax larvae. We present a cas...

The aim of this article is to present a rare case of myiasis caused by Dermatobia hominis. Myiasis is a disease caused by invasion of tissues of animals and humans by larval stages of dipterous (2-winged) flies. There are few reports of oral myiasis in the literature, mostly related to Cochliomyia hominivorax larvae. We present a case of a 53-year-...

Medication-related osteonecrosis of the jaws (MRONJ) can be considered an inability of the alveolar bone to respond to an injury, which frequently leads to severe local and systemic complications. Once the problem is installed, dentist must use all therapeutic approaches recommended. This manuscript reports a successful management of MRONJ handled...

Mucoepidermoid carcinoma ex pleomorphic adenoma (MCxPA) is a rare salivary gland tumor predominantly found in major salivary glands. A case of MCxPA involving the soft tissue and bone of the retromolar region of a 26-year-old man is presented. The histopathological features revealed a neoplasm with predominance of pleomorphic adenoma (PA) elements,...

This study aimed to understand how patients perceive their oral health and the resulting oral manifestations of antineoplastic chemotherapy, as well as to analyze the impact of these alterations on oral health-related quality of life. A total of 80 patients undergoing treatment participated in this study. A questionnaire was applied using the Oral...

Dental treatment of patients with leukemia should be planned on the basis of antineoplastic therapy which can be chemotherapy with or without radiotherapy and bone marrow transplantation. Many are the oral manifestations presented by these patients, arising from leukemia and/or treatment. In addition, performing dental procedures at different stage...

A boa comunicação escrita é uma habilidade essencial para a troca de informações entre profissionais da saúde. No contexto do SUS, essa troca ocorre por meio de documentos de referência e contrarreferência. Considerando as lesões bucais que necessitam de avaliação na atenção secundária, documentos de referência permitem avaliar a necessidade clínic...

The objective of this study was to evaluate the cytological content of ameloblastomas of the jaw. Nine cases of ameloblastoma were punctured, and the intralesional material was processed using the cell block technique. After centrifugation, the pellet obtained from the punctured material was fixed in formaldehyde and routinely processed to inclusio...

Central giant cell lesions (CGCLs) are nonneoplastic proliferations with benign tumorlike behavior more common in young patients. Conventional treatment is surgical enucleation. Pharmacological approaches offer an option to reduce lesion volume before surgery, minimizing sequelae. Young man, 14, had a reddish purple swelling of the right maxilla, w...

Patient with difficult-to-manage oral lichen planus, with relapses and exacerbations over a 10-year period, presented with a large ulcerative and foul-smelling intraoral mass in the left maxillary region. The initial clinical diagnosis indicated squamous cell carcinoma with possible association with previous history of lichen planus at the site. Th...

This study investigated the viability of the cell block technique as an auxiliary method of diagnosing jawbone lesions. Thirty-three clinically diagnosed jawbone lesions with a cystic appearance were subjected to aspiration. The aspirated material was processed by the cell block technique, and the lesions were biopsied and treated. Cytological find...

INTRODUÇÃO: A busca por novos métodos que auxiliem e simplifiquem de maneira eficaz o diagnóstico de lesões maxilares, cistos e tumores, objetiva beneficiar os pacientes e facilitar a atuação dos profissionais da área de diagnóstico bucal. Além dos dados clínicos, radiográficos e histopatológicos classicamente utilizados nos protocolos de investiga...

INTRODUCTION: The search for new methods that aid and optimize the diagnosis of cystic and tumoral maxillary lesions aims to benefit both patients and professionals from oral diagnosis. In addition to clinical, radiographic and histological findings traditionally used in research protocol for maxillary lesions, the adaptation of widely used medical...

To evaluate the applicability of the cell block technique as a complementary method for presumptive diagnosis in the analysis of cyst-like aspirates from jaw lesions prior to histopathological diagnosis. The sample was made up of 17 cyst-like jaw lesions. After puncture, the aspirates were centrifuged, fixed in formalin, embedded in paraffin and pr...

The development of the oral squamous cell carcinoma (OSCC) is a multistep process that requires the accumulation of multiple genetic alterations usually preceded by detectable mucosal changes, most often leukoplakias and erythroplakias. The clinical appearance of oral precancerous lesions and their degree of epithelium dysplasia suggests the malign...

Paracoccidioidomycosis is an infection caused by the p. brasiliensis fungus. This is a deep, systemic fungal infection considered endemic in Brazil and some Latin American countries. The fungus is acquired by inhalation, resulting in a pulmonary disease which may also affect the skin, oral, nasal and gastrointestinal mucosa, as well as the spleen a...

La paracoccidioidomicosis es una infección causada por un hongo P. brasiliensis. Se trata de una micosis profunda y sistémica, es considerada una enfermedad endémica en Brasil y en otros países de América Latina. El hongo es adquirido por inhalación, dando lugar a un cuadro clínico pulmonar que puede posteriormente afectar a la piel, mucosa oral, n...

PURPOSE: The enlargement of nasopharyngeal tonsils, which leads to nasal obstruction and subsequent mouth breathing, can be caused by the presence of HIV. The aim of this research was to study nasopharyngeal tonsil sizes in HIV-infected children ranging from 6 to 13 years and to relate these findings to CD4+ T-cell counts and viral loads. METHODS:...

Patient with difficult-to-manage oral lichen planus, with relapses and exacerbations over a 10-year period, presented with a large ulcerative and foul-smelling intraoral mass in the left maxillary region. The initial clinical diagnosis indicated squamous cell carcinoma with possible association with previous history of lichen planus at the site. Th...

5 ABSTRACT The nasolabial cyst is a rare nonodontogenic cyst of slow progression which, depending on its size, can cause facial asymmetry. It is commonly and successfully treated by enucleation, using an intra-oral approach. There is a potential risk of an oronasal fistula when this modality of treatment is employed, owing to the proximity of the c...

OBJETIVO: o objetivo deste estudo foi estudar a associação entre o padrão de respiração e o tamanho da tonsila faríngea em 122 crianças (60 infectadas pelo HIV e 62 sem infecção). MATERIAL E MÉTODO: As crianças foram analisadas quanto ao padrão de respiração, fluxo nasal e ocupação da tonsila faríngea em radiografias cefalométricas de perfil, atrav...

the goal of the present investigation was to study the association between breathing pattern and pharyngeal tonsil size in 122 children (60 HIV infected and 62 without such infection). The children were analyzed as to their breathing pattern, nasal flow and pharyngeal tonsil obstruction seen in side cephalometric x-rays, by means of a computerized...

O carcinoma epidermóide é a neoplasia maligna mais comum de cavidade oral e estruturas adjacentes. Apresenta maior incidência no gênero masculino, após a quarta década de vida, e tem como principais fatores etiológicos os usos crônicos de tabaco e álcool. Neste trabalho é relatado um caso de carcinoma de células escamosas do rebordo alveolar inferi...

Squamous cell carcinoma is the most common malignant neoplasm in oral cavity and adjacent structures. Its prevalence is higher in males, after the fourth decade, and the main etiologic associated factors are smoking and alcohol. This study reports a case of squamous cell carcinoma arising from the lower alveolar ridge, a non-preferential site for t...

Viral coinfection in the oral cavity associated to HIV infection was evaluated in 180 children from birth to 13 years of age of both sexes. The oral examinations were performed at the Pediatric AIDS Outpatient Clinic, São Lucas Hospital and Clinic Hospital, both in Porto Alegre, Brazil and at the School of Dental Medicine, University Hospital Cente...

Os autores descrevem o caso clínico de duas lesões presentes há mais de 4 anos, em uma paciente do sexo feminino, 65 anos de idade, que negou hábitos de tabagismo e etilismo. Uma das lesões encontrava-se em mucosa jugal, lado direito, exofítica, com superfície verrucóide e esbranquiçada; outra localizava-se na borda da língua, lado direito, em form...

Oral manifestations related to HIV infection were evaluated in 184 children of both genders, aging 0-13 years. The oral exams were carried out at the Ambulatory of Pediatric AIDS, São Lucas Hospital and at the Clinics Hospital, both in Porto Alegre, RS, Brazil, and at the University Hospital and School of Dentistry, State University of New York, St...