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Publications (3)
Gradual expansion of PE/PPE family of proteins from non-pathogenic to
pathogenic mycobacteria and their association with other virulent factors supports
their vivid role in mycobacterial virulence and pathogenesis. The evolution of
PE/PPE family proteins is found to be synchronized to that of Esx or Type VII
secretion systems from the saprophytic s...
Tuberculosis, caused by Mycobacterium tuberculosis, remains a leading infectious disease taking one human life every 15 s globally. The two well-characterized strains H37Rv and H37Ra, derived from the same parental strain M. tuberculosis H37, show dramatically different pathogenic phenotypes. PE/PPE gene family, comprising of 176 open reading frame...
