Kavita Sharma

Idaho State University | ISU · Department of Chemistry

The gut microbiota interacts with the host’s immune function, and evidence supports a relationship between the gut microbiota and age-related disease. Consumption of herbs and spices, which contain bioactive compounds such as polyphenols, is associated with gut microbiota characteristics that may act to prevent or manage age-related declines in hea...

This research is an exploratory study on the sesquiterpenes and flavonoid present in the leaves of Artemisia tridentata subsp. tridentata. The leaf foliage was extracted with 100% chloroform. Thin-layer chromatography (TLC) analysis of the crude extract showed four bands. Each band was purified by column chromatography followed by recrystallization...

The present work aims to provide an insight on the chemical constituents of essential oils obtained from six aromatic plants of the Langtang National Park (LNP), Nepal. LNP harbors an enriched biodiversity of medicinal and aromatic plants (MAPs). The composition of essential oils obtained from Rhododendron anthopogon D. Don, Artemisia dubia Wall. e...

Metabolomics is the study of the chemical process that involves small molecule substrates, intermediates and products of cell metabolism. It aims to construct unbiased observations using analytical tools and data analysis (Dias et al., 2012). Allium belongs to the Amaryllidaceae family and is one of the largest monocot genera, comprised of about 10...

The increased consumption of fruits, vegetables, and whole grains contributes to the reduced risk of many diseases related to metabolic syndrome, including neurodegenerative diseases, cardiovascular disease (CVD), diabetes, and cancer. Citrus, the genus Citrus L., is one of the most important fruit crops, rich in carotenoids, flavonoids, terpenes,...

Despite the identification of Aβ plaques and NFTs as biomarkers for Alzheimer’s disease (AD) pathology, therapeutic interventions remain elusive, with neither an absolute prophylactic nor a curative medication available to impede the progression of AD presently available. Current approaches focus on symptomatic treatments to maintain AD patients’ m...

Diverse medicinal plants such as those from the genus Artemisia have been employed globally for centuries by individuals belonging to different cultures. Universally, Artemisia species have been used to remedy various maladies that range from simple fevers to malaria. A survey conducted by the World Health Organization (WHO) demonstrated that 80% o...

A wide range of extractant and Task Specific Ionic liquids have been studied for the removal of lanthanides and actinides from high level liquid waste (e.g. PUREX and TRUEX etc.). The studies showed that extractant/TSILs can extract lanthanides and actinides simultaneously or it can specifically target the extraction of each group separately from s...

Recent interest in biomass-based fuel blendstocks and chemical compounds has stimulated research efforts on conversion and upgrading pathways, which are considered as critical commercialization drivers. Existing pre-/post-conversion pathways are energy intense (e.g., pyrolysis and hydrogenation) and economically unsustainable, thus, more efficient...

Citrus is the largest grown fruit crop on the globe with an annual production of ~110–124 million tons. Approximately, 45–55% of the whole fruit post-processing is generally discarded as waste by the food processing industries. The waste is a huge problem to the environment in terms of land and water pollution along with displeasure from aesthetic...

Air pollution is partly due to the emission of toxic sulfur and nitrogen oxides during fuel combustion. Therefore, these compounds should be removed from fuels. For that, ionic liquids have been recently developed to extract sulfur and nitrogen compounds from petroleum and fuels. Ionic liquids can extract S- and N-containing compounds either simult...

Citrus waste includes peels, pulp and membrane residue and seeds, constituting approximately 40-60% of the whole fruit. This amount exceeds ∼110-120 million tons annually worldwide. Recent investigations have been focused on developing newer techniques to explore various applications of the chemicals obtained from the citrus wastes. The organic aci...

Citrus contains a range of highly beneficial bioactive compounds, such as polyphenols, carotenoids, and vitamins that show antimicrobial and antioxidant properties and help in building the body's immune system. On consumption or processing, approximately 50% of the fruit remains as inedible waste, which includes peels, seeds, pulp, and segment resi...

Supplementary File to the Review Article "Modern Extraction and Purification Techniques for Obtaining High Purity Food-Grade Bioactive Compounds and Value-Added Co-Products from Citrus Wastes" Citrus contains a range of highly beneficial bioactive compounds, such as polyphenols, carotenoids, and vitamins that show antimicrobial and antioxidant p...

Onion (Allium cepa L.) is rich with flavonols which perceived benefits to human health. Flavonols like quercetin and quercetin glycosides from onion solid waste (OSW) have been extracted and tested against enzymes of clinical importance in Alzheimer's disease and diabetes and be shown to have cytotoxic and antioxidant effects. A simple high-perform...

Citrus is one of the largest and most popular fruit crops commercially grown across the globe. It is not only important in terms of economy but is also popular for its nutritional benefits to human and farm animals. Citrus is available in several varieties, all with attractive colors. It is consumed either fresh or in processed form. After processi...

Citrus are one of the most widely cultivated fruit crops. Citrus fruits are rich source of essential vitamins, minerals, fibers and bioactive phytochemicals, such as alkaloids, carotenoids, nitrogenous compounds and polyphenolics. The by-products derived from citrus wastes are considered to be an economic and renewable source for valuable compounds...

Citrus EOs is an economic, eco-friendly and natural alternatives to chemical preservatives and other synthetic antioxidants, such as sodium nitrites, nitrates or benzoates, commonly utilized in food preservation. Citrus based EOs is obtained mainly from the peels of citrus fruits which are largely discarded as wastes and cause environmental problem...

Quantitative investigation and systematic studies of quercetin, total phenolics, flavonoids, antioxidants, antibacterial and antibiofilm or antibiofouling properties of methanolic extracts of onions obtained from six different varieties have been carried out to explore their relative merits in terms of biological activities of fresh and aging onion...

A facile access to 3-heterosubstituted (3-oxazolidinonyl/indolyl/phenoxy) imidazo[1,2-a]pyridines from readily available 2-aminopyridines and electron-rich (internally activated) alkynes like ynamides/ynamines/ynol ethers is achieved via Cu(OTf)2-mediated intermolecular diamination under aerobic conditions. The reaction is highly regioselective, ow...

This study aimed to determine the flavonol glycosides from onion solid waste (OSW) using HPLC analysis, with antioxidant and enzyme inhibitory activities. We found considerable amount of quercetin-4’-O-monoglucoside (QMG: 254.85), quercetin-3,4’-O-diglucoside (QDG: 162.34), quercetin (Q: 60.44), and isorhamnetin-3-glucoside (IMG: 23.92) (mg/100 g)...

Indole derivatives have attracted significant attention in organic synthesis and bioactivity research owing to their substantial biological activity. In the present study, several 3-naphthylindole analogues were synthesized by direct arylation of 1-diazonaphthalene-2-(1H)-ones by rhodium(II)-catalyzed cross-coupling reaction and their antioxidant a...

An efficient and facile green synthesis of spirooxindole derivatives bearing pyrano[2,3-c]pyrazole moiety has been achieved via a CeO2\documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \beg...

A highly efficient and facile thermal multicomponent cascade reaction of readily available 4-oxo-4H-chromene-3-carbaldehydes with cyanoacetates or cyanoamides and anilines or aliphatic amines under solvent and catalyst-free conditions was developed for the synthesis of a range of polysubstituted 2-aminopyridine derivatives in good to excellent yiel...

Onion (Allium cepa L.) is one of the most commonly cultivated crops across the globe, and its production is increasing every year due to increasing consumer demand. Simultaneously, huge amounts of waste are produced from different parts of the onion, which ultimately affect the environment in various ways. Hence, proper usage as well as disposal of...

[This corrects the article DOI: 10.1007/s13197-015-2076-9.].

Onion stored at 4, 10, and 25 °C for 9 months were analyzed for changes in quercetin and its glucosidase content, enzymes, pyruvic acid, and sugar content. During storage, concentration of quercetin and its glucosidase showed an irregular variation at all studied temperature but at 4 °C the rate was high as compared to 10 and 25 °C. The enzymatic a...

Biologically interesting 2-aryl-2,3-dihydroquinolin-4(1H)-ones were synthesized using a mild and efficient one-pot procedure starting from o-aminoacetophenones and aromatic aldehydes in the presence of silver(I) triflate. This synthetic protocol provides rapid access to a variety of 2-aryl-2,3-dihydroquinolin-4(1H)-ones. This technique has several...

Onion is one of the most cultivated crops and its production is increasing worldwide. Proper handling and storage will add huge benefits to the supply of onion to meet the demand of consumers. For storage, it is important to understand onion physiology from the day it has been harvested from the field until it reaches the market. This review summar...

The purpose of the study was to investigate the decomposition of onions under anaerobic and aerobic conditions. The main aim was to determine the changes in composition of quercetin-related compounds and sugars, with simultaneous analysis of total phenolics, total flavonoids and antioxidant activity. The results indicate that anaerobic conditions l...

Heating effect on total phenol, flavonoids, antioxidant activity, and sugar content of six onion varieties has been quantitatively investigated to explore the effect of different temperatures. The onion varieties comprised one red-skinned variety, two white-skinned varieties, and three yellow-skinned varieties. The heating temperature was scanned a...

Quercetin and quercetin glucosides are the major flavonol present in onion (Allium cepa L.) and is predominantly present as quercetin, quercetin-3,4’-diglucoside and quercetin-4’-glucoside. Effect of different light wavelengths on onion after harvest and storage, with fluorescent, blue, red and ultra violet light influenced the quercetin and querce...

Onion is undoubtedly one of the major sources of flavonoids. However, there exists a varietals difference in composition, concentration and beneficial activities of onion, on the basis of cultivars, Day length sensitivity/ripening and types. To characterize such differences, 18 onion cultivars from Korean were evaluated for their total phenolics, f...

Extraction of antioxidants from aloe gel powder with water–ethanol solvents was studied using response surface methodology. The independent variables were solvent composition, temperature, extraction time, and the liquid-tosolid (L/S) ratio. The concentrations of potentially antioxidant compounds (aloin A and B, aloesin, total phenolics, and total...

Post-storage deterioration of onion under ambient conditions (temperature 20–25 °C and relative humidity 60%–80%), subsequent to a cold storage period of 8 months, was investigated with an emphasis on changes in chemical composition of flavonols, sugars and phenylalanine. A simultaneous determination of total phenolics, total flavonoids and antioxi...

A comprehensive quantitative analysis of flavonoids, sugars, phenylalanine, and tryptophan have been carried out in different onion scales during storage at ambient temperature (20–23 °C) and relative humidity (60–80 %). Depending on the length of storage, dry matter content and composition shows variation inside the onion bulbs. Inner sprouts were...

Post-storage deterioration of onion under ambient conditions (temperature 20–25 °C and relative humidity 60%–80%), subsequent to a cold storage period of 8 months, was investigated with an emphasis on changes in chemical composition of flavonols, sugars and phenylalanine. A simultaneous determination of total phenolics, total flavonoids and antioxi...

Salt-tolerance was studied in transgenic potato. It was conferred by overexpression of ascorbate pathway enzyme (d-galacturonic acid reductase, GalUR). As genetic engineering of the GalUR gene in potato enhances its ascorbic acid content (l-AsA), and subsequently plants suffered minimal oxidative stress-induced damage, we now report on the comprehe...

The enantioselective adsorption of several dipeptides on the crown ether-based stationary phase ChiroSil RCA(+) was studied by means of the linear chromatography method. The retention of analytes was measured with acidified water-methanol mobile phases with varied concentration of methanol (from 60 to 90%, v/v) at different temperatures. Thermodyna...

The mass transfer kinetics of alanyl-alanine enantiomers in a column packed with a chiral stationary phase (CSP) ChiroSil RCA(+) was studied by means of the moment method. Methanol-water solutions acidified with sulphuric acid were used as the mobile phase. It was shown that the spreading of peaks in the column was strongly affected by abnormal edd...