Juan Jimenez-Cauhe

Hospital Universitario Ramón y Cajal · Departamento de Dermatología

Background: Folliculitis decalvans (FD) is a rare primary neutrophilic scarring alopecia whose etiology has not been completely elucidated yet. Objective: To determine if the follicular microbiota residing in FD-affected hair follicles had a distinct microbiological signature and if an aberrant immune response was present in the pathogenesis of...

Resumen Antecedentes La administración de dosis bajas de rituximab es un protocolo utilizado en diversas enfermedades autoinmunes, que ha demostrado también su eficacia y seguridad para el pénfigo vulgar. Objetivos Determinar si rituximab a dosis bajas es efectivo para el penfigoide ampolloso (PA). Métodos Se trató a los pacientes con PA con un...

Abstract Androgenetic alopecia is one of the most common dermatologic disorders in the daily clinical practice of dermatologists. Despite it is such a common entity, few medications are FDA‐approved for its treatment. Due to this situation dermatologists are often reluctant to try off‐label therapies. This guide's purpose is to review the current a...

Background: Low-dose rituximab is a protocol used in several autoimmune diseases, that has also shown to be effective and safe in pemphigus vulgaris. Objectives: To study whether low-dose rituximab is also effective for bullous pemphigoid. Methods: Patients with BP were treated with a single cycle of two infusions of rituximab 500 mg at an interval...

Background Pliaglis® is a self-occluding topical anesthetic containing a eutectic mixture of 7% lidocaine and 7% tetracaine, with proven efficacy and safety in several trials. Aims To evaluate the effectiveness and safety of Pliaglis® for different dermatological procedures in real-life clinical practice. Methods This retrospective, multicenter s...

A woman presented to the emergency department during the COVID-19 pandemic, reporting a slightly pruritic rash that had developed five days after the onset of fever, cough and malaise.

The coronavirus disease 2019 (COVID‐19) has been associated to a wide clinical spectrum of skin manifestations, including chilblain‐like, urticarial, vesicular, maculopapular, livedoid and vasculitic lesions, among others1,2. However, the exact pathophysiology for the appearance of skin lesions is still unknown. Several hypotheses have been suggest...

Chilblain‐like lesions (CLL) were described early on the coronavirus disease 2019 (COVID‐19) pandemic as red‐to‐violet macules, plaques, or nodules typically appearing at the distal aspects of toes.¹ Although increasing evidence suggests they are COVID‐19‐related,² it is not supported by analytic controlled studies.

Background The major concern regarding the use of low-dose oral minoxidil (LDOM) in the treatment of hair loss is the potential risk of systemic adverse effects. Objective To describe the safety of LDOM for the treatment of hair loss in a large cohort of patients. Methods Retrospective multicenter study of patients treated with LDOM for at least...

The Coronavirus Disease 2019 (COVID‐19) is an infectious disease caused by severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2). Skin lesions have been described in confirmed COVID‐19 patients as potential manifestations of the disease¹. Different prevalence rates have been reported in hospitalized patients from January to May 2020, ranging...

Background low dose oral minoxidil (OM) is an increasingly used treatment for androgenetic alopecia and other types of hair loss. Objectives to analyze available data of patients treated with OM, focusing on safety and adverse effects. Methods a search in PubMed and EMBASE was performed for studies reporting the treatment of alopecia with OM. Ind...

Background: In 2017, we carried out a cross-sectional study with the aim of describing androgenic alopecia (AGA) prescription habits among dermatologists who practice in Spain. Three years later, we repeated this study with the aim of describing the current situation and comparing it with previous data. Material and methods: Descriptive cross-se...

Acute telogen effluvium has been recognised as a dermatological sequela of COVID-19.

Vesicular skin rashes have been associated to the Coronavirus Disease 2019 (COVID‐19), but there is little information about this cutaneous manifestation. We designed a prospective observational study of patients diagnosed with COVID‐19 and vesicular lesions. Clinical characterization of skin findings was conducted by dermatologists. When possible,...

Cutaneous manifestations in patients with COVID‐19 infection are being increasingly reported. Several patterns have been described since the initial report by Recalcati,1 including erythematous maculo‐papular,1 urticarial,1,2 chickenpox‐like,1,3 purpuric peri‐flexural,4 transient livedo reticularis,5 and acro‐ischemic or chilblain‐like lesions.6,7...

Frontal fibrosing alopecia (FFA) is a cicatricial alopecia that results in hair follicle destruction on the frontotemporal hairline. To our knowledge, the association of inflammation with progression of the disease has not been studied prospectively.

We have read with great interest the article: Cutaneous manifestations in COVID‐19: a first perspective by Recalcati S.1 This article is the first report of the cutaneous manifestations in Coronavirus Disease 2019 (COVID‐19) patients during the severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) pandemic in Lombardy, Italy.

Disseminated herpes simplex virus (HSV) is mainly seen in immunocompromised individuals. Atypical lesions can be present in both primary infection and reactivation disease. Compared with the general population, inmunocompromised hosts are at greater risk of increased persistency and severity of clinical manifestations, including severe systemic inv...

Secondary syphilis is a polymorphic condition resulting from the hematogenous and lymphatic dissemination of Treponema pallidum. Human immunodeficiency virus-positive patients are in greater risk of atypical and severe forms of the disease. The most common manifestation is a generalized papulosquamous eruption with variable mucosal involvement. How...

We read with interest the article by W. Chen,1 where they hypothesize that juvenile gangrenous vasculitis of the scrotum (JGVS) may be the male counterpart of Lipschütz ulcers (LU). JGVS has been used to depict the abrupt appearance of scrotal ulcerations in young males, preceded by fever and pharyngeal symptoms, with no abnormalities in laboratory...