Jong-Chan Lee

Daegu Gyeongbuk Institute of Science and Technology | DGIST · Department of New Biology

Optical nanoscopy, also known as super-resolution optical microscopy, has provided scientists with the means to surpass the diffraction limit of light microscopy and attain new insights into nanoscopic structures and processes that were previously inaccessible. In recent decades, numerous studies have endeavored to enhance super-resolution microsco...

STED (stimulated emission depletion) far-field optical nanoscopy achieves resolution beyond the diffraction limit by depleting fluorescence at the periphery of excitation with a donut-shaped depletion laser. What is traded off with the superior resolution of STED nanoscopy is the unwanted elevation of structured background noise which hampers the q...

An optimal size of postembryonic root apical meristem (RAM) is achieved by a balance between cell division and differentiation. Despite extensive research, molecular mechanisms underlying the coordination of cell division and differentiation are still fragmentary. Here, we report that ORESARA 15 (ORE15), an Arabidopsis PLATZ transcription factor pr...

Progress in developing fluorescent probes, such as fluorescent proteins, organic dyes, and fluorescent nanoparticles, is inseparable from the advancement in optical fluorescence microscopy. Super-resolution microscopy, or optical nanoscopy, overcame the far-field optical resolution limit, known as Abbe’s diffraction limit, by taking advantage of th...

Super-resolution microscopy or optical nanoscopy has enabled all-optical observation of nanoscopic objects with resolution beyond Abbe’s diffraction limit. STimulated Emission Depletion (STED) nanoscopy achieves diffraction-unlimited resolution by employing a de-excitation laser with a hollow core in addition to the conventional excitation laser in...

For effective of orchestration of biochemical reactions that are optimized in different physicochemical environments, cells are evolved to carry various non-membranous biomolecular condensates in addition to conventional membrane-bound organelles. Recent studies have revealed that these biomolecular condensates are made up of proteins and RNAs of a...

FUS is a nuclear RNA-binding protein, and its cytoplasmic aggregation is a pathogenic signature of amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD). It remains unknown how the FUS-RNA interactions contribute to phase separation and whether its phase behavior is affected by ALS-linked mutations. Here we demonstrate that wild-typ...

The causative connection between aberrant liquid–liquid phase separation (LLPS) of ribonucleoprotein (RNP) granules and neurodegeneration is well known. LLPS driven by intrinsically disordered proteins has been intensely investigated. However, the role of RNA and RNA–protein interaction in RNP granule assembly, properties, maintenance, and eventual...

STED nanoscopy helped usher in resolution revolution of optical microscopy and has been widely used to study subcellular structures and dynamics. To achieve optical resolution beyond the diffraction limit, STED nanoscopy employs 10⁴-10⁵ times more intense light compared to conventional imaging methods, giving rise to additional background which can...

We demonstrate a coherent and dynamic beam splitter based on light storage in cold atoms. An input weak laser pulse is first stored in a cold atom ensemble via electromagnetically-induced transparency (EIT). A set of counter-propagating control fields, applied at a later time, retrieves the stored pulse into two output spatial modes. The high visib...

Einstein-Podolsky-Rosen (EPR) entanglement introduced in 1935 deals with two particles that are entangled in their positions and momenta. Here we report the first experimental demonstration of EPR position-momentum entanglement of narrowband photon pairs generated from cold atoms. By using two-photon quantum ghost imaging and ghost interference, we...

The spatial and spectral properties of entangled photons from spontaneous parametric down-conversion (SPDC) with a focused pump are investigated with theoretical analysis and numerical simulation. Here, the spatial and spectral properties of down-converted photons are fully calculated without using the transverse momentum conservation assumption. W...

Entanglement is known to be an essential resource for many quantum information processes. However, it is now known that some quantum features may be acheived with quantum discord, a generalized measure of quantum correlation. In this paper, we study how quantum discord, or more specifically, the measures of entropic discord and geometric discord ar...

We report on the preservation of transverse spatial coherence of an optical pulse stored in atomic vapor quantum memory. The high visibility Young-type spatial fringes formed by interference between the retrieved and the delayed optical pulses clearly demonstrate that the atomic vapor quantum memory based on electromagnetically induced transparency...

The nonclassical photon pair is naturally endowed with a specific form of frequency-time quantum correlations. Here, we report complete control of time quantum correlations of narrowband biphotons generated in a cold atomic ensemble.

One of the most intriguing features of entanglement is that entangled quantum systems exhibit exchange symmetry; that is, local quantum operations on the subsystems may be interchanged without affecting the quantum state. In this work, we investigate whether the exchange symmetry is preserved for the weak (or partial collapse) measurement, a type o...

When two entangled qubits, each owned by Alice and Bob, undergo separate decoherence, the amount of entanglement is reduced, and often, weak decoherence causes complete loss of entanglement, known as entanglement sudden death. Here we show that it is possible to apply quantum measurement reversal on a single-qubit to avoid entanglement sudden death...

The nonclassical photon pair, generated via a parametric process, is naturally endowed with a specific form of frequency-time quantum correlations. Here, we report complete control of frequency-time quantum correlations of narrow-band biphotons generated via spontaneous four-wave mixing in a cold atomic ensemble. We have experimentally confirmed th...

Wheeler's delayed-choice experiment illustrates vividly that the observer plays a central role in quantum physics by demonstrating that complementarity or wave-particle duality can be enforced even after the photon has already entered the interferometer. The delayed-choice quantum eraser experiment further demonstrates that complementarity can be e...

We report on the preservation of transverse spatial coherence of an optical pulse stored in atomic vapor quantum memory. The high visibility Young-type spatial fringes formed by interference between the retrieved and the delayed optical pulses clearly demonstrate that the atomic vapor quantum memory based on electromagnetically induced transparency...

We report the generation of nonclassical narrowband photon pairs via the spontaneous four-wave mixing process in a cold Rubidium (87Rb) cloud prepared in a magneto-optical trap. The generated photon pairs exhibit strong violation of the Cauchy-Schwarz inequality by a factor of 625 ± 45, confirming nonclassical correlation between the photons. The b...

Decoherence, often caused by unavoidable coupling with the environment, leads to degradation of quantum coherence. For a multipartite quantum system, decoherence leads to degradation of entanglement and, in certain cases, entanglement sudden death. Tackling decoherence, thus, is a critical issue faced in quantum information, as entanglement is a vi...

We report the experimental demonstration of the Young's double-slit type spatial quantum interference of the three-photon N00N state, showing three times denser non-classical spatial interference fringes than that of the single-photon state.

Although non-commutativity of a certain set of quantum operators (e.g., creation/annihilation operators and Pauli spin operators) has been shown experimentally in recent years, the commu- tation relation for the position and the momentum operators has not been directly demonstrated to date. In this paper, we propose and analyze an experimental sche...

The depolarizing quantum operation plays an important role in studying the quantum noise effect and implementing general quantum operations. In this work, we report a scheme which implements a fully controllable input-state independent depolarizing quantum operation for a photonic polarization qubit.

Decoherence, often caused by unavoidable coupling with the environment, leads to degradation of quantum coherence. For a multipartite quantum system, decoherence leads to degradation of entanglement and, in certain cases, entanglement sudden death. Tackling decoherence, thus, is a critical issue faced in quantum information, as entanglement is a vi...

Spatial interference of quantum mechanical particles exhibits a fundamental feature of quantum mechanics. A two-mode entangled state of N particles known as N00N state can give rise to non-classical interference. We report the first experimental observation of a three-photon N00N state exhibiting Young's double-slit type spatial quantum interferenc...

Taming decoherence is essential in realizing quantum computation and quantum communication. Here we experimentally demonstrate that decoherence due to amplitude damping can be suppressed by exploiting quantum measurement reversal in which a weak measurement and the reversing measurement are introduced before and after the decoherence channel, respe...