Jawaid Sial

National Institute of Cardiovascular Diseases (NICVD) · Department of Adult Cardiology

Background: We conducted this study to assess the compliance with secondary rheumatic prophylaxis among preoperative patients with rheumatic mitral valve disease undergoing valvular heart surgery at a tertiary care cardiac hospital in a developing country. Methods: This is a descriptive cross-sectional study conducted at a tertiary care cardiac...

This case report documents the clinical journey of a 22-year-old male who was initially diagnosed with Rheumatoid Arthritis (RA) and later, at the age of 11, with Juvenile Idiopathic Arthritis (JIA). The patient manifested atypical symptoms, primarily marked by sudden and intense chest pain accompanied by sweating, leading to a collapse during his...

Objective The current study was designed to explore the relationship of TIMI and SYNTAX risk score to predict the CAD extent and severity in STEMI patients. Methods For this cross-sectional study, 304 STEMI patients undergoing PPCI were enrolled at Department of Interventional Cardiology NICVD Karachi from September 2021 to January 2022. and the T...

Objectives Smoking is a potent risk factor for coronary artery disease, but there is controversy about its protective nature in terms of prognosis in ST-elevation acute coronary syndrome patients undergoing primary percutaneous coronary intervention. So, the main objective of this study is to unfold this controversy in a South Asian population in t...

Background: Cardiogenic shock (CS) is a life-threatening complication of acute myocardial infarction with high morbidity and mortality rates. Primary percutaneous coronary intervention (PCI) has been shown to improve outcomes in patients with CS. Aim: To investigate the immediate mortality rates in patients with CS undergoing primary PCI and ide...

The incidence of premature ischemic heart disease (IHD) is increasing because of urbanization, a sedentary lifestyle, and various other unexplored factors, especially in South Asia. This study aimed to assess the distribution of premature ST-elevation acute coronary syndrome (STE-ACS) with its clinical and angiographic pattern along with hospital c...

Background Acute hyperglycemia is considered an independent prognosticator of both in-hospital and long-term outcomes in patients with acute coronary syndrome (ACS). This study aimed To analyze the incidence of acute hyperglycemia and its impact on the adverse in-hospital outcome in patients with STE-ACS undergoing primary percutaneous coronary int...

Background Prodromal symptoms are warning signs of an impending acute myocardial infarction (AMI). However, they are often overlooked by both patients and primary clinicians, and little is known about them. Therefore, this study aims to assess the frequency and types of prodromal symptoms in patients with AMI. Methodology This descriptive cross-sec...

Background: In this study, we aimed to assess and compare the distribution of demographic and clinical characteristics and composite adverse clinical outcomes after primary percutaneous coronary intervention (PCI) among "very premature", "premature", and "non-premature" patients with "ST-segment elevation acute coronary syndrome (STE-ACS)" present...

Objectives: The objective of this study was to investigate the immediate and short-term mortality rates among patients with ST-segment elevation myocardial infarction (STEMI) complicated by cardiogenic shock (CS) who underwent primary percutaneous coronary intervention (PCI). Methodology: This observational study was conducted at a tertiary care ca...

Objectives Obesity is a globally well-established risk factor for atherosclerotic cardiovascular diseases; however, some studies have witnessed survival benefits among obese patients and this phenomenon is termed ‘the obesity paradox’. Our aim was to evaluate the existence of an obesity paradox in patients with ‘ST-elevation acute coronary syndrome...

Objective Knowledge regarding the short-term outcomes after same-day discharge (SDD) post primary percutaneous coronary intervention (PCI) is lacking. In this study, we evaluated 1-year major adverse cardiovascular events (MACE) among SDD patients after primary PCI. Design 1-year follow-up analysis of a subset of patients from an existing prospect...

Objectives: Post-dilatation with non-compliant (NC) balloons is a commonly used strategy to improve inadequate stent expansion but this strategy carries an increased risk of slow flow/no-reflow (SF/NR) due to distal embolization. Therefore, our objective was to evaluate the demographic, clinical, angiographic, and procedure characteristics among pa...

Objectives: To determine the frequency of pre-hospital aspirin use in patients presenting with ST- segment elevation myocardial infarction and to assess the demographic and clinical characteristics of the patients taken pre-hospital aspirin. Methodology: It was a prospective study conducted at tertiary care hospital for the duration of six months....

Objectives: The presence of concomitant obstructive coronary artery disease (CAD) in patients with valvular heart disease (VHD) carries significant prognostic implications. Therefore, the objective of this study was to determine the frequency and severity of obstructive CAD in patients undergoing valvular heart surgery for rheumatic heart disease (...

Objectives: Objective of this study was to assess the difference in terms of presentation and in-hospital course between patients with right vs. left dominant arterial circulation undergoing “primary percutaneous coronary intervention (PCI)” for culprit proximal left anterior descending artery (LAD). Methodology: We included consecutive adult (≥18...

Objectives: Unlike “ST-segment elevation myocardial infarction (STEMI)”, there is a wide spectrum of ECG changes for Non-STEMI (NSTEMI) patients with varying prognostic implications. Therefore, the purpose of this study was to determine the frequency of ECG changes in patients with positive high-sensitive troponins (hs-cTn) presenting with NSTEMI....

Hypertension has been recognized as a global health concern. In developing countries, it is not addressed and described to the extent that the actual prevalence of the disease makes it necessary. In these countries, control of blood pressure (BP) remains suboptimal. Worldwide BP reduction is a serious issue, and the situation is more alarming situa...

Background: Distal embolization due to microthrombus fragments formed during predilation ballooning is considered one of the possible mechanisms of slow flow/no-reflow (SF/NR). Therefore, this study aimed to compare the incidence of intraprocedure SF/NR during the primary percutaneous coronary intervention (PCI) in patients with high thrombus burd...

Background: The results of the IABP-SHOCK II trial did not encourage the use of an intra-aortic balloon pump (IABP) in cardiogenic shock (CS) with ST-elevation myocardial infarction (STEMI). We aimed to determine whether these findings may be applicable to our population in the South Asian region, as there is a paucity of data. Methods: In this pr...

Objective: This study was conducted to compare the predictive power of Shock Index (SI), TIMI Risk Index (TRI), LASH Score, and ACEF Score for the prediction of in-hospital mortality in a contemporary cohort of ST-segment elevation myocardial infarction (STEMI) patients undergoing primary percutaneous coronary intervention (PCI) at a tertiary care...

Objectives: Unlike "ST-segment elevation myocardial infarction (STEMI)", there is a wide spectrum of ECG changes for Non-STEMI (NSTEMI) patients with varying prognostic implications. Therefore, the purpose of this study was to determine the frequency of ECG changes in patients with positive high-sensitive troponins (hs-cTn) presenting with NSTEMI....

Objectives: Aim of this study was to assess the difference in terms of presentation and in-hospital course between patients with right vs. left dominant arterial circulation presenting with STE-ACS and undergoing primary percutaneous coronary intervention (PPCI). Methodology: A total of 2680 patients presenting with STE-ACS and undergoing PPCI in o...

Objectives: This study was conducted to compare the predictive power of Shock Index (SI), TIMI Risk Index (TRI), LASH Score, and ACEF Score for the prediction of in-hospital mortality in a contemporary cohort of ST-segment elevation myocardial infarction (STEMI) patients undergoing primary percutaneous coronary intervention (PCI) at a tertiary care...

Objectives: Contrast induced nephropathy (CIN) is a common complication seen after primary percutaneous coronary intervention (PCI) which can contribute to increased morbidity and mortality in patients of acute ST elevation myocardial infarction (STEMI). Aim of this study was to validate the TIMI Risk Index (TRI) for the risk stratification of CIN...

Objectives: The acute hyperglycemia on admission is considered to be in independent prognosticators of both in-hospital and long-term outcome regardless of diabetic status in patients with acute coronary syndrome (ACS). The objective of this study was to analyse the incidence of acute hyperglycemia and its impact on subsequent adverse in-hospital o...

Objectives: Main objective for this study to unfold this controversy in South Asian population in terms of clinical, angiographic parameters and its in-hospital outcomes. Methodology: In this study, we included 1756 consecutive patients diagnosed with STEMI undergoing primary PCI. Patients were classified into smokers and nonsmokers. Comparison was...

Background: Rheumatic heart disease is one of the most frequent types of acquired heart disease, and it is one of the leading causes of morbidity and death. Awareness of doctors regarding rheumatic fever and how to prevent it is important for primary and secondary prevention. Objective: The study aimed to assess the knowledge of rheumatic fever and...

Objectives: Active lifestyle is mandatory for prevention of atherosclerotic cardiovascular diseases. The present study was aimed to identify the physical activity of doctors as well as their knowledge and attitude toward the American College of Cardiology (ACC) recommended physical activity. Methodology: For this survey, an online questionnaire was...

Objectives: This study was designed to compare the in-hospital outcomes of primary PCI with export vs. primary PCI with the balloon in patients with total occlusion. Methodology: Consecutive patients with STEMI undergoing primary PCI with TA and pre-balloon dilatation were recruited in 1:1 ratio and post-procedure in-hospital mortality and complica...

Objectives: The objective of this study was to determine the significance of left ventricular end diastolic pressure (LVEDP) for risk stratification of contrast-induced acute kidney injury after primary percutaneous coronary intervention (PCI). Methodology: This cross-sectional study was conducted at the largest cardiac care center of the Pakistan....

Objective The aim of this study was to compare TIMI flow after administering intracoronary (IC) medications through various routes for the treatment of slow flow/no-reflow during primary PCI. Methods Two independent parallel cohorts of the patients who underwent primary PCI for STEMI and developed slow/no-reflow were recruited. Selection of cohort...

Background: Contrast induced nephropathy (CIN) is a common complication seen after primary percutaneous coronary intervention (PCI) which can contribute to increased morbidity and mortality in patients of acute ST elevation myocardial infarction (STEMI). Aim of this study was to validate the TIMI Risk Index (TRI) for the risk stratification of CIN...

Objective: This study aimed to assess the changes in the perceptions and practices during the coronavirus disease-2019 (COVID-19) era before and after vaccination and antibodies titer among the healthcare workers (HCWs) at a tertiary care cardiac center. Materials and Methods: This descriptive study included HCWs working at a tertiary care cardiac...

Objective: To evaluate the outcomes of transradial approach in terms of procedural failure in patients undergoing percutaneous coronary intervention. Methods: We have enrolled a total of 276 patients who consented for percutaneous coronary intervention through trans-radial approach at National Institute of Cardiovascular diseases, Karachi. Baseline...

Introduction: Slow flow/no reflow (SF/NR) phenomenon during emergency percutaneous revascularization is a feared complication associated with increased risk of adverse outcomes. CHA2 DS2 -VASc score has been proposed for the risk stratification but a very limited evidences are available regarding the accuracy of this system. Therefore, we conducted...

Objectives: Primary percutaneous coronary intervention (PCI) remains recommended reperfusion therapy for patients with acute ST-elevation myocardial infarction. This study aimed to evaluate the short-term major adverse cardiac events (MACE) and their determinants among patients who underwent primary PCI at a tertiary care cardiac center of Karachi...

Background: The presence of conduction defects complicates AMI frequently and is associated with increased short and long term mortality rates. The occurrence of complete heart block in anterior wall myocardial infarction is important because it indicates that infarction is extensive and may result in cardiac failure or death. Objective: To determi...

Background: Improvement in left ventricular (LV) function after revascularization is an important determinant of long-term prognosis in a patient with acute myocardial infarction (AMI). However, data on the changes of LV function after revascularization are scarce in our population. Hence, this study was conducted to evaluate the changes in LV fun...

Objectives: No-reflow is a complication that frequently occurs after stenting during primary percutaneous coronary intervention. In this study, we focused on angiographic results and clinical outcomes after no-reflow in the left anterior descending (LAD) artery versus non-left anterior descending artery ST-elevation myocardial infarction (STEMI)....

Background: Stent thrombosis (ST) remains the most feared complication of percutaneous coronary intervention (PCI). Therefore, this study aimed to determine acute and sub-acute ST incidence, predictors, and outcomes after primary PCI. Methods: This prospective observational study included patients who had undergone primary PCI at a tertiary care...

Objectives: Contrast induced nephropathy (CIN) is a common complication and found to be associated with increased morbidity and mortality after primary percutaneous coronary intervention (PCI). The objective of this study was to validate the Mehran Risk Score (MRS) for the risk stratification of CIN in patients undergone primary PCI. Methodology: A...

Background: Acute coronary syndrome (ACS) is a rapidly growing concern, especially among younger urban communities. We aimed to study age-based differences in clinical and angiographic profiles and outcomes in an urban population. Methods: This study recruited 2 independent, equal-sized cohorts of consecutive patients with ACS undergoing coronary a...

Background The coronavirus disease 2019 (COVID-19) vaccinations have brought new hope to the world and have a significant psychosocial impact on communities as well as healthcare systems around the globe. This study aimed to assess the antibody titer level among healthcare workers after at least six weeks of the second dose of the COVID-19 vaccine....

Background: Aim of this study was to perform quantitative evaluation of high thrombus burden (Grade ≥4) as an independent predictor of slow/no reflow phenomenon during primary percutaneous coronary interventions (PCI) of patients with ST-segment elevation myocardial infarction (STEMI). Methods: In this analytical cross-sectional study we include...

Objective: To determine the frequency of failure of ST-segment resolution after primary percutaneous coronary intervention (PCI) in patients with ST-segment elevation acute myocardial infarction (MI). Methodology: This cross-sectional study was carried out at the CCU department of the National Institute of Cardiovascular Diseases (NICVD) Karachi, d...

In this study, we developed and validated a novel risk stratification model to predict slow-flow/no-reflow (SF/NR) during the primary percutaneous coronary intervention (PCI), namely the RK-SF/NR score. A total of 1,711 consecutive patients with ST-segment elevation myocardial infarction (STEMI) undergone primary PCI. A novel risk stratification mo...

Background: Coronary Artery Disease (CAD) is a complex interaction of genetic and multifactorial environmental factors. This study was conducted to evaluate the association of blood groups with the severity of coronary artery lesions in patients with acute myocardial infarction undergoing primary percutaneous coronary intervention (PCI).

Background Intracoronary epinephrine has been effectively used in treating refractory no-reflow, but there is a dearth of data on its use as a first-line drug in normotensive patients in comparison to the widely used adenosine. Methods In this open-labeled randomized clinical trial, 201 patients with no-reflow were randomized 1:1 into intracoronar...

Objectives: To compare the frequency of severe mitral regurgitation after percutaneous mitral balloon valvuloplasty (PMBV) via Inoue balloon and multi-track balloon technique in our population. Methodology: In this retrospective observational study which was conducted at a tertiary care cardiac center of Karachi, Pakistan between 2015 and 2020 on H...

Objectives: Acute coronary syndrome (ACS) at a younger age is now becoming a crucial problem. This study determined the effect of gender on the clinical findings and outcomes of young patients (≤ 45 years) with ACS. Methodology: In this descriptive cross sectional study, young patients (≤45 years) who presented with ACS and underwent coronary angio...

Objectives: Non-ST elevation acute coronary syndrome (NSTE-ACS) comprises NSTE myocardial infarction (NSTEMI) and unstable angina. A common complexity of NSTE-ACS is heart failure (HF). The objective of this study was to assess the incidence of in-hospital HF in NSTE-ACS patients and to link clinical and electrocardiographic (ECG) abnormalities to...

Objective Promising results of CHA2DS2-VASc score have been reported for the prediction of contrast-induced acute kidney injury (CI-AKI) after percutaneous coronary intervention (PCI). However, data of its predictive strength in the context of primary PCI are not available. Therefore, in this study, we have assessed predictive value of CHA2DS2-VASc...

Objectives This study aimed to compare Mehran Risk Score (MRS) with three well -known scoring systems namely CHA2DS2-VASc score, Canada Acute Coronary Syndrome Risk Score (C-ACS), and Thrombolysis in Myocardial Infarction risk index (TRI) to predict the contrast-induced acute kidney injury (CI-AKI) after primary percutaneous coronary intervention (...

Background: Primary percutaneous intervention is a life-saving procedure to open the occluded coronary artery. Most of these patients have either total occlusion of artery or have high thrombus burden.Therefore, timely use of thrombus aspiration catheters have a significant importance in terms of morbidity and mortality. Purpose: To assess the effe...

Background High intensity statins are recommended in patients with acute coronary syndrome. Statins inhibit atherosclerotic plaque formation in the coronary arteries and reducing the burden of ischemic heart disease, therefore decreasing the morbidity and mortality. Muscle symptoms are most common adverse effect of statins. Hence, the aim of this s...

Objectives: To evaluate the quality of life (QOL) after percutaneous coronary intervention (PCI) using short-form health survey (SF-36) questionnaire at a tertiary care hospital in Pakistan. Methodology: It was a cross-sectional study conducted at a tertiary care cardiac center in Pakistan. A total of 433 adult patients who undergone PCI at least s...

Objective: To determine the frequency of acute stent thrombosis after primary percutaneous coronary intervention in patients with ST-elevation myocardial infarction. Study Design: Descriptive cross sectional study. Place and Duration of Study: Methodology: One hundred and sixty three patients will undergo primary percutaneous coronary intervention...

Objectives: For Southern Asian countries like Pakistan, there is inadequate evidence of risk factors associated with mortality in patients suffering from acute coronary syndrome (ACS), especially non-ST elevation ACS (NSTE-ACS) cases. Therefore, aim of this study was to evaluate predictors of 6-months mortality of patients presenting with NSTE-ACS....

Background Promising results of CHA2DS2-VASc score have been reported for the prediction of contrast induced nephropathy (CIN) after percutaneous coronary intervention (PCI). However, data of its predictive strength in the context of primary PCI is not available. Therefore, in this study, we have assessed predictive value of CHA2DS2-VASc score for...

Acute coronary syndrome (ACS) with early onset of age (especially in <30 years) is an infrequent (up to 0.05 to 0.4%) but serious entity, with modest available data. A rise in incidence has been witnessed, especially in South Asia. The aim was to ascertain the proportion of very young patients (≤35 years) among all adult patients with ACS and impor...

Objectives: To determine the pattern of coronary artery diseases (CAD) in patients under 40 years of age with acute coronary syndrome (ACS) presenting at Hyderabad Satellite Center of National Institute of Cardiovascular Disease (NICVD), Pakistan. Methodology: This cross-sectional study was conducted at cardiology department of the NICVD, Hyderabad...

Objective: ST-segment elevation myocardial infarction (STEMI) at younger age though infrequent but very crucial entity, but there is dearth of available data, however, a rising trend has noticed recently in Asian countries. The aim was to see the territorial and clinical profile influence on overall outcomes of young individuals (≤35 years) with ST...

Objective This study aimed to assess the duration of pre-hospital delay among ST-Segment Elevation Myocardial Infarction (STEMI) patients and its contributing factors. Methodology A cross-sectional study was conducted at Rural Satellite Center in Larkana, Pakistan from May to September 2020. A total of 240 STEMI patients who underwent primary percu...

Objective: Acute pulmonary edema (APE) is a common problem presenting in emergency department of cardiology units. For decades, the mainstay of treatment in APE has been loop diuretics; mainly furosemide. Studies regarding mortality benefits of diuretics in APE patient have not been conducted in our population, where other drugs of heart failure ar...

Objective: ST-segment elevation myocardial infarction (STEMI) at younger age though infrequent but very crucial entity, but there is dearth of available data, however, a rising trend has noticed recently in Asian countries. The aim was to see the territorial and clinical profile influence on overall outcomes of young individuals (≤35 years) with ST...

Background Contrast-induced nephropathy (CIN) after primary percutaneous coronary intervention (PCI) is associated with increased mortality and morbidity. The aim of this study is to determine the frequency of CIN after primary PCI and its association with risk factors in patients with ST-segment elevation myocardial infarction (STEMI) at a tertiar...

Objectives: To determine the frequency of dual antiplatelet adherence at six months after primary PCI performed at rural satellite center. Methodology: This was a descriptive study conducted at Rural Satellite Center (Larkana) of the National Institute of Cardiovascular Disease, Pakistan from October 2017 to March 2018. Patients of either gender be...

Background and objective: Depression and anxiety are very common in patients with cardiac diseases. Percutaneous coronary intervention (PCI) has not only decreased mortality but angina, heart failure and recurrent hospitalization all are improved. Therefore, anxiety and depression associated with fibrinolytic therapy in acute coronary syndrome (AC...

Background: The thrombosis of the stent is one of the most important complications of percutaneous interventions, resulting in complete occlusion of the stented vessel. Aim of this study was to determine the validity of Stent Thrombosis Risk Score (STRS) in predicting early stent thrombosis (ST) after primary Percutaneous Coronary Intervention (PC...

Introduction Primary percutaneous coronary intervention (PPCI) is now a well-established treatment of acute ST-elevation myocardial infarction (STEMI). For the first time in Pakistan, various off-site satellite centers are established to perform PPCI 24-hours. Our population mainly resides in the rural area with low literacy rate and poor socioecon...

Background This study was conducted with the aim of providing a quantitative appraisal of clinical outcomes of trans-radial access for primary percutaneous coronary interventions (PCI) in patients with ST-segment evaluation myocardial infarction (STEMI). Methods In this study, we compared two propensity-matched cohorts of patients who underwent pr...

OBJECTIVE: To study the proportion of positive exercise stress test in younger patients coming to tertiary care hospital for the evaluation of ischaemic heart disease (IHD). Our secondary objective was to find out the difference of risk profile between the relatively younger and elderly population having IHD. METHODOLOGY: This descriptive cross sec...

Background: Even though percutaneous coronary intervention (PCI) improved the survival of patients with acute myocardial infarction, still multivessel coronary artery disease remains an important factor burdening prognosis and it is being associated with a worse prognosis compared to single-vessel disease (SVD). Aim: To compare the clinical prof...

Objectives: To determine the frequency of dual antiplatelet adherence at six months after primary PCI performed at rural satellite center. Methodology: This was a descriptive study conducted at Rural Satellite Center (Larkana) of the National Institute of Cardiovascular Disease, Pakistan from October 2017 to March 2018. Patients of either gender b...

Objective: To assess and identify various factors which are responsible for hospital admission of patients with heart failure at coronary care unit of a cardiac center in rural areas of Sindh, Pakistan. Methodology: This cross-sectional study included consecutive patients admitted to the coronary care unit (CCU) of Chandka Medical College Hospital...

Objective: To compare angiographic characteristics and outcomes of primary percutaneous coronary intervention between young and old patients presenting with acute ST Elevation Myocardial Infarction. Methods: The prospective observational study was conducted at the National Institute of Cardiovascular Diseases, Karachi, from December 17, 2016, to J...

Objectives: In the present study, we analysed the incidence of no-reflow phenomenon, its clinical and procedural predictors, and associated in-hospital outcomes for the patients undergoing primary percutaneous coronary intervention (PCI). Background: No-reflow phenomenon after primary PCI is a procedural complication associated with adverse post...

Objective: This prospective study was undertaken to determine contrast amount and factors responsible for increasing contrast volume in patients undergoing cardiac diagnostic and therapeutic catheterization. Background: Due to increase number of cardiac catheterization procedures safety concerns are an issue nowadays. Contrast induced nephropathy,...

Background & Objective Due to increase in number of cardiac catheterization procedures safety concerns is an issue nowadays. Multiple diagnostic modalities use radiations, which also put a patient at higher cumulative radiation exposure. Therefore steps should be taken to minimize radiation exposure during cardiac catheterization. Hence determinati...

ABSTRACT Objective:To determine adherence to secondary prophylaxis of rheumatic fever in patients with rheumatic heart disease presenting to cardiology department. Methodology: This cross-sectional study was conducted at Cardiology department of Chandka Medical College Larkana from 15th January to 14th April 2015. Patients with documented history...

Objective: To determine frequency of contrast-induced nephropathy (CIN), andpost procedure complications in-hospital mortality in patients after undergoingPrimary Percutaneous Coronary Intervention for acute ST-Elevation MyocardialInfarction (STEMI). Methodology: This cross sectional study includes patients, who underwentprimary percutaneous coron...

Objective: To compare the coronary angiographic characteristics of coronary artery disease in young patients of less than and equal to 40 years of age with those of more than 40 years of age. Patients and Methods: Observational study conducted from Sept to Jan 2003-2004. A total of 299 patients of Coronary Artery Disease were included in the study....

Introduction The number of cardiac patients increases on a daily basis, and emergency departments bear much of the burden of non-cardiac patients due to pathological fears of the aftermath of the disease. Therefore, this study aimed to determine the burden of non-cardiac patients on the emergency department of a cardiac center in a rural area of Si...

Iatrogenic aortic dissection caused by primary percutaneous coronary intervention (PCI) is a rare but potentially fatal complication; therefore prompt recognition of this life-threatening condition is crucial. We present herein a case of a 70-year-old lady who underwent primary PCI for transmural myocardial infarction of left anterior descending ar...

A 70-year diabetic and hypertensive lady admitted with acute coronary syndrome (ACS) underwent coronary angiography, which showed severe diffuse disease of proximal left anterior descending (LAD). She underwent percutaneous coronay intervention (PCI) of proximal LAD artery that resulted in occlusion of jailed first septal perforator. She remained s...

Objective: Methodology: Results: Conclusion: Key Words: To determine frequency of contrast-induced nephropathy (CIN), and post procedure complications in-hospital mortality in patients after undergoing Primary Percutaneous Coronary Intervention for acute ST-Elevation Myocardial Infarction (STEMI). This cross sectional study includes patients, who u...

Objective: To know the predictors of a successful outcome of percutaneous transvenous mitral commissurotomy (PTMC) other than described in the Wilkins scoring system. Methods: Two hundred fifty-eight consecutive patients were enrolled for this observational study in a tertiary care heart center of Pakistan who had a Wilkins score of ≤8. Patients wi...