Jan Janczak

Institute of Low Temperature and Structure Research Polish Academy of Sciences 50-422 Wrocław Poland

Although the crystals of coordination polymer {[CuCl(μ-O,O’-L-Br2Tyr)]}n (1) (L-Br2Tyr = 3,5-dibromo-L-tyrosine) were formed under basic conditions, crystallographic studies revealed that the OH group of the ligand remained protonated. Two adjacent [CuCl(L-Br2Tyr)] monomers, bridged by the carboxylate group of the ligand in the syn-anti bidentate b...

A new Zn II coordination polymer (CP) based on 2,3-pyrazine dicarboxylic acid (H 2 pzdc) and 4,4′-bipyridine (bpy) (ZCP) was synthesized using a facile slow evaporation method. Single-crystal X-ray diffraction revealed that ZCP is a two-dimensional porous CP, [Zn 2 (pzdc) 2 (bpy)(H 2 O) 2 ] n , with van der Waals forces as the dominant interaction...

Combretastatins isolated from the Combretum caffrum tree belong to a group of closely related stilbenes. They are colchicine binding site inhibitors which disrupt the polymerization process of microtubules in tubulins, causing mitotic arrest. In vitro and in vivo studies have proven that some combretastatins exhibit antitumor properties, and among...

A binuclear copper (II) complex [Cu2(dien)2(ox)(ClO4)] (dien = diethylenetriamine and ox = oxalate) was readily synthesized and obtained in the perchlorate salt form. The structure of the compound has been determined using X‐ray crystallography, UV–Vis spectroscopy, and infrared techniques. This new catalyst has effectively facilitated the producti...

A new organic-functionalized Cu-based Anderson-type polyoxomolybdate, namely (C7H15N4)2[Na(H2O)4]2[C6H12CuMo6N2O24]·2(H2O) (CuII-POM), was synthesized via a simple one-pot reaction and subsequently characterized using a range of analytical and spectral techniques. Structural investigation by single crystal X-ray diffraction analysis revealed that t...

The single crystals of the title compound (1) were grown from a water solution. The compound crystallizes in the centrosymmetric space group P21/c of the monoclinic system with eight molecules per unit cell. Multiple recrystallizations of the crystals from heavy water gives deuterated analogue 1d. The asymmetric unit of 1 contains two salt molecule...

In this study, key features of metronidazole (MNZ) cocrystal polymorphs with gallic acid (GAL) and gentisic acid (GNT) were elucidated. Solvent-mediated phase transformation experiments in 30 solvents with varying properties were employed to control the polymorphic behavior of the MNZ cocrystal with GAL. Solvents with relative polarity (RP) values...

Designing multifunctional catalysts for one‐pot organic transformations is highly important due to economic and environmental point of views. Synthesis of bifunctional acid–base tandem catalysts has drawn attention owing to the incorporation of antagonistic active sites in a single catalyst. In the current work, a novel coordination polymer, [NaZn(...

A new dimethyl-substituted bipyridine-Zn(II) complex was synthesized and structurally characterized. Single-crystalline structure of the complex was successfully elucidated as [Zn(2Mebpy)3](ClO4)2•1.5(dioxane) by X-ray diffraction, where 2Mebpy represents 4,4′-dimethyl-2,2′-bipyridine. Also, the three-dimensional electrostatic potential maps (3D ES...

By means of single-crystal X-ray diffraction analysis, vibrational, optical, photoluminescence, and thermal examination, a novel crystal of 2-amino-3-picolinium arsenate has been produced and described. The developed crystal crystallized in triclinic crystal system with centrosymmetric space group P-1 was confirmed by single-crystal XRD investigati...

A newly binuclear nickel(II) complex, [Ni2(en)4(ox)](ClO4)2 (1) (where en = ethylenediamine, and ox = oxalate), has been isolated from a reaction of NiCl2·6H2O, ethylenediamine, ammonium oxalate and sodium perchlorate in water and its crystal structure has been determined by X-ray crystallography and infra-red techniques. Compound 1 was successfull...

This study is aimed to understand the structure, stability, and properties of L-argininium 3,3-dimethylacrylate (ADMA) crystals. These single crystals were cultivated through a solution growth method. The structure describes the orthorhombic crystal system with four molecules per unit cell, and crystallizes in a non-centrosymmetric (P212121) space...

The herbicides azafenidin [(2-(2,4-dichloro-5-prop-2-ynoxyphenyl)-5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-a]pyridin-3-one)] and flumetsulam [(N-(2,6-difluorophenyl)-5-methyl-[1,2,4]triazolo[1,5-a]pyrimidine-2-sulfonamide)] were subjected to IR, Raman, UV-Vis and emission studies. As triazolopyridine is the most prominent and active component of thes...

In this study, we present a novel organic hybrid Ni-based δ-isomer of Anderson-type polyoxometalates (POMs), namely, δ-[C 6 H 12 Mo 6 N 2 NiO 24 ] ⁴⁻ ( 1 ), as an efficient catalyst for the cycloaddition reaction between alkynes, halides, and sodium azide. Synthesis of the catalyst was performed using a facile one-pot method followed by characteriz...

A new polymer of Mn (II) formulated as [(NIH) (Cl) Mn1 (µ-NIH)2 Mn2(Cl)) (H2O)2] [(NIH) (H2O) Mn3 (µ-NIH)2Mn4(H2O)3]n.6Cl·4H2ONIH, where NIH = 4-Pyridinecarboxylic acid hydrazide = Isoniazid = Isonicotinic acid hydrazide has been synthesized and characterized by elemental analysis, Fourier-transform infrared spectroscopy) FT-IR (, thermogravimetric...

A new polyoxomolybdate with a formula of [(C 6 H 12 N 4 -CH 3 ) 2 Na 2 (H 2 O) 8 ](C 6 H 12 N 4 -CH 3 ) 2 [(H 0.5 )N(CH 2 O) 3 FeMoO 18.5 (OH) 2.5 ] 2 ·10H 2 O (1) was synthesized. The structure of the synthesized polyoxomolybdate was investigated by single crystal X-ray diffraction analysis and several other identification techniques such as FT-IR...

In recent years, significant advances have been made in the precise control of the physical properties of metal–organic frameworks (MOFs) via the linker-modulated method in which modulators compete with linkers and impose kinetic limitations through crystal growth. In this regard, the structure of a new barium–organic framework [Ba(H2BTC)2(H2O)4]n,...

We report the synthesis and structural, spectroscopic and magnetic properties of new 1D coordination polymeric complex {[Cu(μ-l-Arg)2]SO4⋅1.5H2O}n (1) that contains asymmetric μ−O,O’ carboxylic bridge linking distorted square-pyramidal [Cu(μ-l-Arg)2]²⁺ coordination units. In 1D, the syn−anti−μ²−η¹:η¹zigzag polymer conformation, the adjacent Cu(II)...

3 cda = chel = chelidamic acid, bpy = 2,2 ′-bipyridine) through one-pot synthesis. In 1, the tridentate Hcda 2− ligand, an enol tautomer of the 4-hydroxypyridine type, and a bpy molecule coordinate the Cu(II). In 2, the same tautomer of the tridentate H 2 cda − ligand (with one deprotonated carboxylic acid), along with bpy, forms a cationic [Cu(H 2...

Two copper(II) chelidamate compounds with N, N'-bipyridine were obtained as crystals [Cu(Hcda)(bpy)(H2O)]∙2H2O (1) and [Cu(H2cda)(bpy)(H2O)](H2cda) (2) (H3L = H3cda = chel = chelidamic acid, bpy = 2,2’−bipyridine) through one-pot synthesis. In 1, the tridentate Hcda²⁻ ligand, an enol tautomer of the 4−hydroxypyridine type, and a bpy molecule coordi...

We report the synthesis and structural, spectroscopic and magnetic properties of new 1D coordination polymeric complex of the formulae {[Cu( µ −l−Arg) 2 ]SO 4 ⋅1.5H 2 O} n ( 1 ) that contains asymmetric µ − O,O’ carboxylic bridge linking distorted square-pyramidal [Cu( µ −l−Arg) 2 ] ²⁺ coordination units. In 1D the syn − anti − µ ² − η ¹ : η ¹ zig-...

Three new 2-N-methylamino-4-nitropicoline-(3, 5 or 6) N-oxides were synthesised. Their structures were characterized on the basis of X-ray diffraction studies carried out for one of the isomers. The IR, Raman, electron UV-VIS and emission spectra measurements were conducted and analysed in terms of theoretical data. Quantum chemical DFT and NBO cal...

The single crystals of [1-(diaminomethylene)thiouron-1-ium] pyridine-3-carboxylate were grown using a solution growth technique. Depending on the concentration of the 1: 1 amidinothiourea: nicotinic acid solution, two different forms of 1: 1 crystal (orthorhombic non-centrosymmetric, P212121,(1), and monoclinic centrosymmetric, C2/c, (2)) were obta...

The detailed investigation of the structural and spectroscopic characterization of the products formed in aqueous solution of hydrazine and maleic acid is studied in the current research. Single crystal X-ray diffraction inquiry concedes that obtained crystal hydrazinium fumarate (1) crystallises in the centrosymmetric space group P21/c of the mono...

Two new chromium and copper complexes containing 4′-(4-quinolyl)-2,2′:6′,2′'-terpyridine (qtpy) have been synthesized and characterized using elemental analysis, IR and X-ray crystal structure determination. The reaction of CrCl3.6H2O with qtpy in presence of granulated zinc as a reducing agent has been resulted in the formation of the new terpyrid...

The slow evaporation solution growth approach was used to generate a single crystal of urea-DL-malic acid (UDLMA). Single crystal X-ray diffraction was used for the structural analysis of obtained 1:1 co-crystal. A systematic study of structure, intra and intermolecular bonding interactions, vibration, excitation energies and electrostatic potentia...

A supramolecular dimeric complex [Ag(dppf)(NO3)]2 was prepared via the reaction of a solution of AgNO3 in methanol/dichloromethane with 1,1′-bis(diphenylphosphino)ferrocene (dppf) which was fully characterized by IR, elemental analysis, multinuclear NMR (1H, 13C and 31P) spectroscopy and X-ray crystal structure determination. The crystal structure...

The reaction of Zn(NO3)2⋅6H2O with tpyOH or ftpy in the presence of KSCN affords the new zinc(II) complexes [Zn(tpyOH)(NCS)2] (1) and [Zn(ftpy)(NCS)2] (2) while two isostructural compound of [Zn(tpyOH)(NCS)2].DMSO (1.DMSO) and [Zn(ftpy)(NCS)2].DMSO (2.DMSO) were obtained during the crystallization in DMSO, respectively. Structurally, 1.DMSO and 2.D...

In the current work, a new polyoxovanadate (POV)-based material, NH 4 V 3 O 8 ( 1 ), has been synthesized via hydrothermal process. Single crystal X-ray diffraction analyses of 1 shows a 2D structure in which the {V 3 O 8 } ⁻ n layers are joined through hydrogen bonding interactions with NH 4 ⁺ . The POV compound was further analyzed by powder X-ra...

A unique hetero-nuclear complex formulated as [Cu(pydc)2Mn(H2O)5].2H2O (1) where pydc²⁻ = pyridine-2,6-dicarboxylato has been synthesized through a facile and environment-friendly ultrasonic reaction. Complex 1 was characterized by various techniques, including single-crystal X-ray diffraction (SC-XRD). X-ray crystallographic analysis reveals that...

Salinomycin (SAL), a monocarboxylic polyether antibiotic isolated from Streptomyces albus is widely used in veterinary medicine as a growth promoter and as a supplement in poultry feed to control infection with coccidia. SAL exhibits also potent activity against the proliferation of various cancer cells, including those that display multidrug resis...

A new antimony(III)–phthalocyanine complex with the formula of [(SbPc)2(Sb2I8)(SbBr3)]2 has been obtained in the reaction of pure antimony powder with phthalonitrile under the oxidation conditions by iodine monobromide vapors. The complex crystallizes in the centrosymmetric space group of the triclinic system. Both independent (SbPc)+ units exhibit...

The structural and spectroscopic properties of a new triazolopyridine derivative (1,2,4-triazolo[4,3-a]pyridin-3-amine) are described in this paper. Its FTIR spectrum was recorded in the 100–4000 cm−1 range and its FT-Raman spectrum in the range 80–4000 cm−1. The molecular structure and vibrational spectra were analyzed using the B3LYP/6-311G(2d,2p...

Herein a simple method for N-methylation of ethanolamines with paraformaldehyde as a dual methylation and reducing agent has been investigated. Two new cobalt complexes, Co[Methyl 6-(morpoline methyl) picolinate]2Cl2 and Co(2,6 bis morpholine methyl pyridine)Cl2 were prepared and applied as homogeneous catalyst in reductive methylation reaction. Al...

New antimony(III) phthalocyanine complex under iodine vapor atmosphere, (SbIIIPc)(I3).½(I2), (1), was obtained. The (SbIIIPc)(I3).½(I2) crystallizes in the centrosymmetric space group of the triclinic system. The (SbPc)⁺ unit is non-planar Two inversion related (SbIIIPc)(I3) units interact each other via neutral I2 molecule yielding {[C32H16N8Sb](I...

A water-insoluble Keggin-type polyoxomolybdovanadate nanocluster, (Et4N)4[VMo12O40]·MeCN (1) was synthesized and crystallized in acetonitrile. The catalyst was characterized by X-ray crystallography, UV–Vis, thermogravimetric analysis (TGA), cyclic voltammetry (CV), and FT-IR techniques. Degradation of organic dyes, Amido black 10B (AB10B) and Meth...

Reaction of 2-imino-4-thiobiuret with boric acid (in molar ration of 1:1) in aqueous solution at the mild conditions leads to formation of a heterocyclic compound of 2,2-dihdroxy-4-amino-6-thio-1,3,5-trihydrotriaza-2-boracyclohex-3-en (1). This compound crystallizes directly from the reaction solution after a few days, giving light yellowish transp...

Dimethyltin(IV) complex SnMe2(NCS)2 form two coordination polymers when react with the tetradentate 2,2′-bipyrimidine (bpym) ligand. The reaction of SnMe2(NCS)2 with 2,2′-bipyrimidine in a mole ratio of Sn:bpym/2:1 resulted in the formation of [SnMe2(NCS)2(bpym)]·SnMe2(NCS)2 (1) while the reaction of SnMe2(NCS)2 with bpym in a mole ratio of Sn:bpym...

The single crystals of 1-(diaminomethylene)thiouron-1-ium 2-pyridinecarboxylate, (C2H7N4S)-(C5NH4COO), (1) suitable for the X-ray analysis were grown using a solution growth technique room temperature. Recrystallization of 1 in heavy water (three-times) yield respective deuterated analogue, (C2D7N4S) (C5NH4COO), (1d). The X-ray analyses show that b...

A new Ag(I) metal-organic framework (Ag-MOF) [Ag(p-OH-C6H4COOH)2(NO3)]n ([Ag(PHBA)2(NO3)]n, (1) (PHBA: C8H6O4 {p-hydroxybenzoic acid}) was synthesized using two different methods; laying method (single crystal) and sonochemical irradiation (nanostructures). Scanning electron microscopy (SEM), powder XRD, and FT-IR spectroscopy were used to characte...

In this paper we present the synthesis method and a detailed description of the crystal structure, as well as thermal, dielectric and phonon properties, of the [CH3NH2CH2CH2NH2CH3][Zn2(HCOO)6] (dmenH2-Zn) metal organic framework. The negative charge of the anionic framework ([Zn2(HCOO)6]2-) is balanced by N,N′-dimethylethylenediamine (dmenH22+) ion...

A series of mono‐ and bis‐terpyridine complexes of nickel (II) based on the 4′‐(furan‐2‐yl)‐2,2′:6′,2″‐terpyridine (ftpy) have been synthesized and structurally characterized using elemental analysis, infrared spectroscopy, and single crystal X‐ray diffraction. The reaction of NiCl2•6H2O with ftpy has been resulted in the formation of new bis‐terpy...

Colchicine shows very high antimitotic activity, therefore, it is used as a lead compound for generation of new anticancer agents. In the hope of developing novel, useful drugs with more favourable pharmacological profiles, a series of doubly modified colchicine derivatives has been designed, synthesized and characterized. These novel carbamate or...

The single crystals of 1-(diaminomethylene)thiouron-1-ium 4-aminobenzoate, (C2H7N4S)-(NH2C6H4COO), (1) suitable for the X-ray analysis were grown using a solution growth technique room temperature. Recrystallization of 1 in heavy water (three-times) yield respective deuterated analogue, (C2D7N4S)(ND2C6H4COO), (1d). The X-ray single crystals analyse...

A step-by-step synthesis based on the application of monoprotected 2.6-diformylpyridine intermediate resulted in the formation of enantiopure Eu(III), Yb(III) and Y(III) complexes of unsymmetrical macrocycles L³ and L⁴ containing two pyridine units and two different diamine and diimine links. The final step in the formation of these mixed amine-imi...

Nano-structures of two mononuclear Zn(II) complexes, [ZnL2Br2] (1) and [ZnL6].2(I) (2) L=1-methyl imidazole ligand, were synthesized using a sonochemical method and characterized by infrared spectroscopy (IR), UV-Visible, X-Ray powder diffraction (XRPD), scanning electron microscopy (SEM) and elemental analyses. The single-crystal X-ray (SCXA) data...

New europium and terbium [LnCl3L3(H2O)2] polycrystalline complexes were synthesized with the ligand L = 3-bromo-4-methylthio-2,6-lutidine N-oxide. IR, Raman, electron absorption UV-VIS and emission spectra measurements were carried out for these compounds. Re-crystallization of these materials led to formation of single crystals with another compos...

A series of zinc(II) phthalocyanine complexes peripherally octa-substituted by methyl groups and with axially ligated N-donor ligands, (Zn(Me)8Pc-L, where L is pyridine (4), 3-methylpyridine (5), 3,4-lutidine (6) and 3,5-lutidine (7)), was synthesized. All the Zn(Me)8Pc-L complexes 4-7 were obtained in the crystalline form, suitable for X-ray singl...

New chemical compounds have been synthesized and their physicochemical properties have been characterized. N'-[2,4-dihydroxyphenyl) methylidene]-4-(4-fluorophenyl) piperazine-1-carbothiohydrazide, a novel semi-carbazone has been obtained in the three stages of intermediate process and by the final crystallization from the methanol solution. The fin...

The single crystals of 1-(diaminomethylene)thiouron-1-ium 3-nitrobenzoate monohydrate, [C3H7N6][C6H4(NO2)(COO)].H2O, (1) suitable for the X-ray analysis were grown using a solution growth technique at room temperature. The first order phase transition of (1) was detected by differential scanning calorimetry (DSC) measurements. The room temperature...

Four new praseodymium(III) metal–organic compounds varying in dimensionality from 0D to 3D have been designed and synthesized based on N-heterocyclic polycarboxylic acids, including pyridine-2,6-dicarboxylic acid (H 2 pydc) and pyrazine-2,3-dicarboxylic acid (H 2 pzdc). Altering the concentration of piperazine (pip, ancillary ligand) enables contro...

A novel inorganic complex formulated as [Co(dipic)(2,2´-bipyridine) (H2O)]3 × 10H2O, where dipic²⁻ = pyridine-2,6-dicarboxylato has been synthesized via a facile sonochemical process. Molecular structure of inorganic complex was characterized by several methods. The results of single crystal X-ray diffraction (SCXRD) revealed that the complex cryst...

The importance of dopamine (DA) detection as a biomarker for several diseases, especially Parkinson''s disease, has persuaded scientists to develop new nanomaterials for efficient sensing of DA in clinical samples. Ultrathin metal-organic nanosheets due to their exceptional thickness, large surface area, and flexibility are endowed with many access...

This scenario was designed to investigate the protein corona pattern on the pillar-layer surface of a Cu-based metal–organic framework (MOF) in human plasma. The [Cu(L)(L/)].1.3DMA (MOF-1) {L = 4, 4/-bipyridine and L/ = 5-aminoisophthalic acid}, was synthesized through the sonochemical irradiation approach as well as characterized by various techni...

The global concern related with growing number of bacterial pathogens, resistant to numerous antibiotics, prone scientific environment to search for new antimicrobials. Antiseptics appear to be suitable candidates as adjunctive agents to antibiotics or alternative local treatment option aiming to prevent and treat infections. 1,2-benzothiazines are...

A new paramagnetic hetero-nuclear complex formulated as [K3Fe(μ-ox)3(H2O)3]n (1), where ox2- is oxalate has been synthesized under hydrothermal condition. Molecular structure of complex 1 was characterized by elemental analysis, Fourier-transform infrared spectroscopy (FT-IR) and single-crystal X-ray diffraction (SCXRD). The results of SC-XRD analy...

Large blue rectangular crystals of the 2D layered coordination polymer 1 have been obtained. The interest for this complex is two-fold. First, complex 1 is made of 2D layers packing along the (0-11) direction favored by the presence of lattice and coordinated water molecules. And second, nanostructures that could be derived by delamination are pote...

Materials engineering plays a pivotal role considering its manifold applications, i.e., in medicine as individualized drug carriers or in advanced technologies such as optoelectronic devices and others. Recently, increasing interest in the pyrazoline derivatives family of compounds was noticed. In this paper, we report on the constitutional isomeri...

In this paper, we show a strategy to modify salphen-type Schiff base ligands with naphtol (SYML1) and pyrocathecol (2,3-dihydroxyphenyl) groups (SYML2), or a combination of both (ASYML). Each of these ligands can be used to obtain polynuclear metal complexes following two different strategies. One relies on using metals that are either too large fo...

A dimeric tungstophosphate, Na14[Co4(PW9O35)2].28H2O (1), was synthesized via a simple one-pot method and characterized by single-crystal X-ray crystallography. Nanocluster 1 was exhibited to be able to selective oxidation of aliphatic and aromatic sulfides to sulfoxides in the presence of hydrogen peroxide at room temperature with high performance...

Colchicine is a well-known compound with strong antiproliferative activity that has had limited use in chemotherapy because of its toxicity. In order to create more potent anticancer agents, a series of novel colchicine derivatives have been obtained by simultaneous modification at C7 (amides and sulfonamides) and at C10 (methylamino group) positio...

New 1D coordination polymer (CP); namely, [Cd(L)(N3)2]n (1) [L = 2-Picolylamine], was synthesized using branch tube method. Using sonochemical method led to the achievement of nano and micro structures of 1. These structures have been characterized by FT-IR spectroscopy, elemental analysis, powder X-Ray diffraction (P-XRD) and scanning electron mic...

A new two dimensional nanoscale Copper(II) coordination polymer (CP), [Cu2(pydc)2(bpy)(H2O)2]n(1), where pydc = pyridine-2,5-dicarboxylic acid and bpy = 4,4ʹ-bipyridine, was synthesized using a sonochemical method. CP1 was characterized by scanning electron microscopy (SEM), elemental analysis, FT-IR spectroscopy and X-ray powder diffraction (XRD)...

The development of novel 2D materials, due to the promising applications they have enabled through their unique properties, has attracted increasingly more research interest. In this regard, novel dual-emitting coordination polymer nanosheets were developed by doping Eu3+ and Tb3+ ions into the nanostructures of the [Ba(DPA)2(H2O)2]n (DPA = dipicol...