Homa Babaei

Kermanshah University of Medical Sciences | KUMS · neonatology

Background: Lumbosacral agenesis or caudal regression syndrome (CRS) is a rare congenital malformation represented with symmetrical sacrococcygeal or lumbosacrococcygeal agenesis with a varied incidence between 1 per 25000 live births to 2.5 per 100000 live births. Additionally, manifold abnormalities may be associated with CRS, including spinal co...

Analyzing child mortality, an important indicator of health and development of countries, can help policymakers to develop health programs that resulted in improving Childs’s health. Recognizing the causes of in-hospital deaths also assists health caregivers to revise their medical services. The aim of this study was to explore the causes of death...

Background: Pentalogy of Cantrell (PC) is an extremely rare congenital anomaly which was first described in 1985. The incidence of the PC has been reported to vary from 5.5-7.9 cases per million live births. This anomaly involves diaphragmatic pericardial defects, lower sternal defect, intracardiac anomalies, ventral abdominal wall abnormality, and...

Amaç: Bu çalışmanın amacı, sırtüstü ve yüzüstü konumların nazal sürekli pozitif hava yolu basıncı (N-CPAP) altındaki preterm bebeklerin fizyolojik parametreleri üzerindeki etkilerini karşılaştırmaktır.Gereç ve Yöntem: Bu çapraz klinik çalışma, İran' Kermanşah'taki İmam Reza Hastanesi Yenidoğan yoğun bakım ünitesinde N-CPAP altındaki 62 hastaneye ya...

Introduction: Patent ductus arteriosus (PDA) is one of the most common cardiac problems in preterm neonates which could lead to morbidities, such as chronic lung disease, intraventricular hemorrhage and retinopathy. The aim of this study was to evaluate the effect of oral acetaminophen on closure of PDA in preterm neonates. Methods: Sixty-nine neon...

Objectives: Bilirubin, a by-product of heme degradation, is suggested to have a role for vascular protection. There is increasing evidence that bilirubin may directly affect the function and secretory activity of endothelial cells. In this study, potential effect of hyperbilirubinemia on biological features of circulation endothelial progenitor ce...

Retinopathy of prematurity (ROP) is a result of increased pathological neoangiogenesis of the retina in preterm infants. Cells responsible for the pathogenesis of ROP are unclear, but some evidence indicates that bone marrow derived cells are involved in this disorder. Endothelial progenitor cells (EPCs), play a role in angiogenesis in response to...

Background: Despite the reduction of infant mortality in the world, complication of preterm birth is a major cause of infant mortality. The present study aimed to evaluate the effect of abdominal massage and non-nutritive sucking on physiological parameters of preterm infants in neonatal intensive care units in Emam Reza Hospital in Kermanshah, Ira...

Many infants who develop bronchopulmonary dysplasia (BPD) are born with serious respiratory distress syndrome (RDS), which is associated with impaired vascular and alveolar growth. RDS is a breathing disorder that mostly affects preterm infants and occurs in infants whose lungs have not yet been fully developed. The use of surfactant in RDS treatme...

Background: Newborns are fully capable of pain perception, and uncontrolled pain, especially in the early life will impose unwanted effects on the child in the future. This study was performed to compare the analgesic effects of breast milk and 20% dextrose on the pain caused by hepatitis B vaccination in term neonates. Methods: In this randomized...

Introduction: Gastrointestinal Tract Obstruction (GITO) is one of the most common causes of surgical emergencies in newborns. Management of these patients depends on the site of obstruction, associated anomalies, the time of diagnosis and the surgery. Aim: The purpose of this study was to evaluate clinical manifestations, associated anomalies and t...

Objective: Diabetes mellitus is the most common chronic endocrine disease worldwide. Intensive glycemic control plays an important role in decreasing morbidity and mortality rate of the disease. Preclinical studies have shown that biotin has an essential role in regulating blood glucose and serum lipid metabolism. This study aims to evaluate the ef...

Jaundice is a common problem in neonatal period. Phototherapy is the most common treatment for neonatal jaundice. The purpose of this study was to determine the effect of adding white plastic cover around the phototherapy unit on hyperbilirubinemia in full term neonates with jaundice. In this randomized controlled trial, over 12 months (October 200...

Background and aim: About one-third of the world's population has some serologic evidence of suffering infection by hepatitis B virus (HBV). One of the effective measures for reducing the mortality because of hepatitis B virus is vaccination at birth time, 2 months and 4 months old. The criterion for effectiveness of hepatitis B vaccine is enough p...

Background and Aim: Respiratory distress syndrome due to lack of enough surfactant in fetal lung tissue is a common cause of neonatal mortality. There are several laboratory methods to predict the amount of fetal lung surfactant. The purpose of this study was to compare lamellar body count test (Quantitative test) and gastric aspirate shake test (Q...

Background and Objective: Milk intolerance due to gastrointestinal dysmotility is a common problem among preterm neonates. Erythromycin has a prokinetic effect on gastrointestinal motility. The purpose of this study was to assess the effectiveness of oral erythromycin in preterm neonates on milk tolerance. Materials and Methods: This clinical trial...

The immune system in premature neonates is weaker compared to mature ones. Zinc is a micro-nutritive, which plays an important role in the immune system. It can function as an adjuvant to improve the effectiveness of some vaccines. Neonate receive zinc in the third trimester of pregnancy, so the preterm neonate cannot receive it adequately and they...

Background and Aim: Transcutaneous bilirubin measurement is a noninvasive method which is associated with decreased pain, less skin injury and lower risk of infection. In addition there is no need to take blood sample. The aim of this study was to determine the clinical accuracy of transcutaneous bilirubinometry (TCB) in comparison to that of total...

To determine incidence and associated risk factors for the development of retinopathy of prematurity (ROP) in very low birth weight infants. This is a cohort study conducted during period of March 2009 to February 2010 in Imam Reza Hospital (AS) as a referral center in Kermanshah (Iran). All very low birth weight infants admitted in neonatal intens...

Background and Objective: The survival rate of newborns not only depends on birth weight and gestational age, but also on other factors including physiological conditions and especially disease severity during the first hours of life. This study was designed to assess different variables and particularly the score for Neonatal Acute Physiology-II (...

To evaluate whether the use of intravenous immunoglobulin in newborn infants with isoimmune hemolytic jaundice due to Rh and ABO incompatibility is an effective treatment in reducing the need for exchange transfusion. This study included all direct Coombs' test positive Rh and ABO isoimmunized babies, who admitted in the Neonatal Intensive Care Uni...