Himanshu Sharma

National College of Ireland · School of Computing

Background: Alzheimer's disease (AD) is the most common form of dementia and is expected to greatly rise in future, making it a major worldwide health concern with severe impacts on individuals and society. Despite advancements in understanding the cellular and molecular aspects of Alzheimer's disease (AD) in recent decades, it still poses a signif...

Biobased materials are goods whose primary ingredients were first taken from living things. The hybrid science known as nanobiotechnology, which was created by the fusion of the two potent technologies of nanotechnology and biotechnology, is a reflection of science’s expanding capacity to conduct research at scales higher than the molecular one and...

The purpose of this review article is to provide a complete overview of the fastdeveloping topic of biobased nanomaterials and the various uses that they have. An extensive study into the utilization of biological resources for nanotechnology has been motivated by the growing demand for materials that are both sustainable and favorable to the envir...

Background: Psoriasis is a persistent immune system disorder that influences the skin, leading to red, flaky patches that can be painful and irritated. Objective: Traditional treatments for psoriasis, such as topical creams and oral medications, may be effective but also have potential side effects. Herbal remedies have been used for centuries to...

Alternative medication is used for treating the common problems associated with pregnancy. 80% of women suffer from morning sickness during pregnancy. Treatment during pregnancy via using non-pharmacological therapy is quite popular all over the world as it is safe and has no negative effects on the fetus. Nausea and vomiting are one of the most pr...

Background: It is estimated that there are over 200 million people living with diabetes mellitus (DM) all over the world. It is a metabolic condition caused by decreased insulin action or secretion. Diabetes Mellitus is also known as Type 2 Diabetes Mellitus. Type 1 diabetes mellitus and type 2 diabetes mellitus are the two most common types of DM....

Objective: Amino-3-hydroxy-5-methyl-4-isoxazole propionate (AMPA) is an ionotropic transmembrane receptor for glutamate. AMPA receptor blockers have been reported to prevent neurological damage and enhance the post stroke recovery in rats. Decanoic acid, a medium-chain fatty acid, has been reported to exhibit non-competitive AMPA receptor antagoni...

The present study evaluates the effect of modulating α-amino-3-hydroxy-5-methyl-4-isoxazole propionate receptor (AMPAR) by inhibiting them in the acute phase and activating them in the sub-acute phase on post-stroke recovery in middle cerebral artery occlusion (MCAo) model of stroke in rats. After 90 min of MCAo, perampanel (an AMPAR antagonist, 1....

Standard deep learning methods, such as Ensemble Models, Bayesian Neural Networks, and Quantile Regression Models provide estimates of prediction uncertainties for data-driven deep learning models. However, they can be limited in their applications due to their heavy memory, inference cost, and ability to properly capture out-of-distribution uncert...

Standard deep learning methods, such as Ensemble Models, Bayesian Neural Networks and Quantile Regression Models provide estimates to prediction uncertainties for data-driven deep learning models. However, they can be limited in their applications due to their heavy memory, inference cost, and ability to properly capture out-of-distribution uncerta...

Ethnopharmacological relevance: In traditional medicine, Glycyrrhiza glabra, commonly known as liquorice, is known to possess promising pharmacological properties including anti-oxidative, anti-inflammatory, gastro, hepato and nephro-protective activities. Aim: The present study investigated the protective effects of Glycyrrhiza glabra rhizome e...

Background Cinnamomum cassia iswidely used as a traditional medicinal plant for the treatment of rheumatoid arthritis. Objective The present study aimed to assess the anti-arthritic activity of C. cassia bark hydroalcoholic extract (CCHE) in different arthritic animal models. Methods In formaldehyde model, sub-plantar administration of 0.1 ml of...