About
23
Publications
706
Reads
How we measure 'reads'
A 'read' is counted each time someone views a publication summary (such as the title, abstract, and list of authors), clicks on a figure, or views or downloads the full-text. Learn more
133
Citations
Publications
Publications (23)
Objectives:
To assess differentially expressed blood proteins between patients with active rheumatoid arthritis (RA) and patients in remission after methotrexate (MTX) treatment, with the aim of identifying a biomarker of methotrexate resistance (MTXR).
Methods:
Two populations of RA patients treated with a stable dose of subcutaneous MTX for at...
Purpose: To evaluate whole-body vibration (WBV) osteogenic potential in physically inactive postmenopausal women using high-frequency and combined amplitude stimuli.
Methods: Two-hundred fifty-five physically inactive postmenopausal women (55–75 years) with 10-year major osteoporotic fracture risk (3%–35%) participated in this 18-month study. For t...
Introduction
À cause des variations de fréquence(haute/basse), d’accélération (< 1/ > 1 g) et du temps d’exposition aux stimuli vibratoires, l’incertitude demeure quant à l’effet ostéogénique des vibrations corps entier (VCE)[1], [2]. L’efficacité des VCE dans une population de femmes ménopausées, a été étudiée avec deux objectifs :
– analyser le p...
Introduction
Le méthotrexate (MTX), traitement de 1ère intention de la polyarthrite rhumatoïde (PR) a un rôle anti-structural, anti rhumatismal et réduit la morbidité cardiovasculaire. Sa demi-vie courte ne lui permet pas d’être dosé en routine. Cependant, le méthotrexate polyglutamate (MTX-PG), formé après conversion enzymatique dans les globules...
Bone microarchitecture assessed by high-resolution peripheral quantitative computed tomography varies across populations of different origin. The study presents a reference dataset of microarchitectural parameters in a homogeneous group of participants aged within 22-27 range determined by a discriminant analysis of a larger cross-sectional cohort...
This observational study prospectively assessed direct and indirect costs related to patient management over 18 months following hip, clinical vertebral, humeral, or distal forearm fracture events in France. It appears that their levels were much higher than the previous estimates, raising the burden of osteoporosis-related fractures on public heal...
Introduction
L’ostéoporose est une maladie diffuse du squelette caractérisée par une masse osseuse basse et des altérations micro architecturales du tissu osseux, conduisant à une augmentation de la fragilité osseuse et du risque de fracture. L’exploration de la masse osseuse est réalisée en pratique courante par la DXA. L’exploration et la mesure...
Résumé
Objectifs
Les altérations osseuses au niveau sous-chondral au cours de la polyarthrite rhumatoïde (PR) font toujours l’objet de recherches. Chez les patients atteints de PR en rémission, l’évolution des dommages de l’os sous-chondral reste inconnue. La persistance d’une inflammation infra-cliniques dans l’articulation pourrait être responsa...
The effects of whole body vibration on musculoskeletal system might depend on the vibration regimen. In this study, a group of 100 sedentary postmenopausal women (55 to 75 years old) were subjected to whole body vibration (35-50 Hz frequency, 0.2-0.8 mm amplitude, 3 sessions/week) while they performed passive and active squat exercises for a period...
Objectives:
Bone alterations at the subchondral level during rheumatoid arthritis (RA) remain under investigation. It remains unknown whether subchondral bone damage might still occur in RA patients in clinical remission, which could then infer suggesting that even minor subclinical inflammatory changes in the joint can induce local bone loss.
Me...
Risk for premature osteoporosis is a major health concern in astronauts and cosmonauts and the reversibility of the bone lost at the weight-bearing bone sites is not established although it is suspected to take longer than the mission length. The bone three-dimensional structure and strength which could be uniquely affected by weightlessness, is cu...
Background Patients with chronic inflammatory rheumatism claim fatigue as a key symptom of their disease. The association between fatigue and inflammatory joint diseases such as rheumatoid arthritis (RA) or axial spondyloarthritis (axSpA) has been considered so far to be mainly related to disease activity. However, many arthritic patients despite h...
Background At this time, no predictive factor for response to biotherapy in RA patients is available in the daily practice.
Objectives The objective is to determine predictive factors for the first biological maintenance in rheumatoid arthritis (RA) treatment.
Methods From our database including 663 RA patients, 289 RA patients were received their...
