Hanadi Alyami

King Fahad Medical City | KFMC · Department of Dentistry

Progresses in the medicinal application of nanocompounds were accepted for the treatment of cancer. Nanoparticles-based therapy is of benefit for effective biodistribution and specific targeting. The current study investigated the anticancer effect of green synthesized platinum nanoparticles (PtNPs) against colon cancer cells (HCT-116). Flow cytome...

One of the most prevalent harmful heavy metals is lead (Pb). It is generally recognized to be harmful to the testicles. Asparagus officinalis has many saponins, flavonoids, and other phenolics with strong antioxidant and anti-inflammatory effects. The effects of A. officinalis (asparagus) aqueous extract (AOAE) on testicular damage caused by lead a...

The ongoing loss of human life owing to various forms of cancer necessitates the development of a more effective/honorable therapeutic approach. Moreover, finding a novel green-synthesized anti-cancer therapy is vital because of the induced drug resistance against the commonly used drugs. Collecting the advantage of the nanometer size of nanopartic...

Oral carcinoma is one of the most vicious forms of cancer with a very low survival rate, as its patients often respond poorly to conventional chemotherapy. Presently several researchers are attempting to pursue an alternative to this therapy using natural products. Considering the promising strategy and induction of apoptosis to target the cancer c...

The role of oxidative stress in the initiation and progress of epilepsy is well established. Proanthocyanidins (PACs), a naturally occurring polyphenolic compound, have been reported to possess a broad spectrum of pharmacological and therapeutic properties against oxidative stress. However, the protective effects of proanthocyanidins against epilep...

Polymorphonuclear neutrophils (PMNs) are indispensable in fighting infectious microbes by adopting various antimicrobial strategies including phagocytosis and neutrophil extracellular traps (NETs). Although the role and importance of PMNs in periodontal disease are well established, the specific molecular mechanisms involved in NET formation are ye...

Subgingival plaque contains a variety of pathogenic bacteria that infect the periodontal tissues. Polymorphonuclear neutrophils (PMNs) utilize a number of antimicrobial strategies including phagocytosis and neutrophil extracellular traps (NETs) to defend this microbial challenge. The signaling pathways and specific molecular mechanisms involved in...