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April 1987 - February 2014
Publications
Publications (44)
Objective:
To evaluate the effectiveness of 200 mg of daily vaginal natural progesterone to prevent preterm birth in women with preterm labour.
Design:
Multicentre, randomised, double-blind, placebo-controlled trial.
Setting:
Twenty-nine centres in Switzerland and Argentina.
Population:
A total of 385 women with preterm labour (24(0/7) to 33...
Tocolysis is an important treatment in the improvement of outcome in preterm labor and preterm birth, provided that its use follows clear evidence-based recommendations. In this expert opinion, the most recent evidence about efficacy and side effects of different tocolytics is being reviewed and evidence-based recommendation about diagnosis and tre...
Es wird empfohlen, bei allen Schwangeren zwischen der 24. und der 28. SSW ein Screening des Gestationsdiabetes mittels oralem Glucosetoleranztest 75g durchzuführen, d.h. Nüchtern-Blutzuckerbestimmung gefolgt von oraler Einnahme von 75g Glucose und Blutzuckerbestimmung nach einer und zwei Stunden. Der Gestationsdiabetes (GDM) ist eine Störung des Gl...
Background: Tension-free vaginal tape (TVT) is a widely used method for the surgical treatment of stress urinary incontinence (SUI). TVT is to considered to be a safe and effective procedure, with an enduring high success rate. This article presents a case of a woman, who had an uncomplicated vaginal delivery 3 years after having underwent a TVT pr...
A spontaneous rupture of an adrenal artery is a rare cause of abdominal pain in pregnancy. We present a case of a pregnant woman who needed to be operated on because of a rupture of the right adrenal artery associated with a fetal bradycardia. An immediate caesarean section was performed. The intra-abdominal palpation identified an extensive retrop...
Introduction: Chylomicronemia syndrome (CS) is a rare disorder characterized by a high level of triglycerides in plasma. We present a case of a pregnant woman with a severe acute pancreatitis (AP) affected by a CS. Case: A 38-year-old gravida 2, para 0 with an uneventful course of pregnancy was referred with an AP at 37 0/7 weeks of gestation. This...
Antenatal maternal administration of corticosteroids has been shown to reduce morbidity and mortality rates in preterm delivery. Threatened spontaneous or medically indicated preterm delivery for maternal or fetal indications between 24 and 34 weeks of gestation with unknown fetal lung maturity status are indications for antenatal corticosteroid ad...
Prophylaxe, Diagnose und Therapie von Störungen des Geburtsablaufes gehören zu den zentralen geburtsmedizinischen Aufgaben. Die Vielzahl möglicher Störfaktoren des Geburtsablaufes lässt das Thema »Pathologische Geburt« komplex erscheinen. Das vorliegende Kapitel ist nach pathogenetischen wie auch praktisch wichtigen Problemstellungen gegliedert. In...
The aim of this study was to evaluate every part of the surgical procedure during cesarean section (CS) to prevent complications
and improve the clinical outcome. We researched on PubMed, Medline, and Cochrane. The evidence-based research suggests a transverse
incision of the skin, blunt dissection of the subcutaneous tissue, omission of the bladde...
Massive feto-maternal hemorrhage (FMH) is rare. Late signs and symptoms are decreased fetal movement (in 35% of cases), unexpected stillbirth (in 12.5% of cases), sinusoidal heart rate (in 1% of cases) or fetal anomalies. Early diagnosis is important to improve the prognosis of the newborn ante partum and in the early postpartum period. We report a...
Massive fetomaternal hemorrhage is rare. Late signs and symptoms are decreased fetal movement (in 35% of cases), still births (in 12.5% of cases), sinusoidal heart rate (in 1% of cases) or fetal anomalies. Early diagnosis is important to improve the prognosis of the newborn in the antepartum and early postpartum period.
We report a single case of...
We report the case of a 31-year-old pregnant woman who had previously undergone surgery and combined chemo-/radiotherapy at the age of 8 years. In the 32nd 5/7 week of pregnancy she had a cesarean section due to cervical insufficiency and amniotic infection syndrome. During the cesarean section, a placenta percreta within an extremely thin myometri...
We report the case of a 31-year-old pregnant woman who had previously undergone surgery and combined chemo-/radiotherapy at the age of 8 years. In the 32nd 5/7 week of pregnancy she had a cesarean section due to cervical insufficiency and amniotic infection syndrome. During the cesarean section, a placenta percreta within an extremely thin myometri...
We report on a 22- year-old woman with postpartum dissection of the left anterior descending artery and the intermediate branch. The patient was treated with acetylsalicylic acid (ASA), clopidogrel, and betablocker only. Coronary angiography performed 20 months later revealed complete resolution of the dissection sites. The patient’s cardiovascular...
Perinatal and infant mortality rates are considered key indicators of medical care. The aim of this investigation was to examine how representative and reliable the official national figures of Switzerland are by comparing them with the data in local birth registers.
124 of 156 maternity hospitals in Switzerland, catering for about 80% of all newbo...
A growing publicity drives the growing market of OTC, also in pregnancy. A short overview from this giant market, composed of pharmaceutical drugs, herbal medicines and homeopathic medicaments for a selection of frequent health problems in pregnancy is presented.
Die Versorgung mit Medikamenten auf eigene Initiative gewinnt durch die zunehmende Werbung inkl. neuerdings im Internet zunehmend an Gewicht. Aus dem immensen Angebot an Pharmazeutika, Naturheilmittel und Homöopathika wird eine kleine Auswahl häufiger Medikamente für häufige Probleme in der Schwangerschaft vorgestellt.
The requirements laid down by law and by the medical profession itself with regard to continuing medical education have recently been tightened. The cost of good training is high, both in time and money. Sponsoring, especially by the pharmaceutical industry, has helped to keep costs down for individual participants. The question of a tariff system...
ZusammenfassungDie standeseigenen und gesetzlichen Auflagen an die ärztliche Fortbildung sind in jüngster Vergangenheit erhöht worden. Der Aufwand an Zeit und Geld für gute Fortbildung ist hoch. Das Sponsoring vor allem der Heilmittelindustrie vermochte die Kosten für den einzelnen Teilnehmer tief zu halten. Es stellt sich die Frage nach einer tari...
Lithium medication during pregnancy is uncommon and the problems of a neonate who has been exposed to lithium represents a rare situation in neonatology. The clinical presentation and management of a newborn whose mother received lithium during pregnancy is presented. The newborn manifested a four day course of lethargy with unexplained high lithiu...
A new magnesium sulphate solution with xylitol for the management of hypertensive disorders during pregnancy has been described. The solution contains 40 g MgSO4 and 16 g xylit in 1000 ml and is isoosmotic with blood serum. It can be sterilised for 15 min. at 121 degrees C without risk of decomposition of the ingredients during and after autoclavin...
This is a case report on a nulliparous women, who developed the HELLP syndrome following intravenous tocolysis. Contrary to our expectations, neither schistocytes nor signs of intravasal coagulation were apparent; however, we found Fenoterol-associated anti-erythrocyte antibodies. However, the low titre of these antibodies does not explain the mass...
Eine 35jährige Primigravida entwickelt unter Tokolyse mit Fenoterol das erst kürzlich beschriebene HELLP-Syndrom (Hemolysis, Elevated Liver Enzymes, Low Platelet Count). Entgegen der Erwartung lassen sich bei der Patientin aber keine Fragmentierung der Erythrozyten und keine Zeichen einer intravasalen Gerinnung, hingegen Fenoterol-abhängige, antier...
Ebstein's anomaly is characterized by abnormalities both in the basal and in the free attachments of the leaflets of the tricuspid valve. Fairly frequently the developmental defect is associated with a WPW syndrome (Type B). The main obstetric problems arise from tachyarrhythmias. Since tachycardias in these patients are due to physical stress, cor...
Ten gravidae with normal course of pregnancy in the third trimester underwent a bicycle stress test (semi-supine, 75 W, 3 min). By means of pulsed Doppler sonography, a lowering of the resistance index (RI) in the maternal femoral artery from 93% to 69% was ascertained, though also a rise in maximum systolic velocity (VMAX (syst)) from 73 cm/sec to...
Ten gravidae with normal course of pregnancy in the third trimester underwent a bicycle stress test (semi-supine, 75 W, 3 min). By means of pulsed Doppler sonography, a lowering of the resistance index (RI) in the maternal femoral artery from 93% to 69% was ascertained, though also a rise in maximum systolic velocity (VMAX (syst)) from 73 cm/sec to...
An zwei Fallbeispielen, einer Patientin mit einer inoperablen Transposition der großen Gefäße und einer Patientin mit einem WPW-Syndrom bei Ebstein' Anomalie, wird das geburtshilfliche Management dargestellt.
Salivary amylase output in man increases after injection of synthetic human calcitonin. This effect is dose dependent.
Synthetic human calcitonin stimulates amylase secretion of salivary glands in man. The same effect has been demonstrated in isolated cells of rat salivary glands. In vitro experiments suggest that the stimulatory effect is a direct action of calcitonin on salivary cells. Salivary secretion is not affected by pancreozymin or secretin. Our findings a...
