Gamze Durhan

Hacettepe University · Department of Radiology

Background Pulmonary vascular involvement is a significant cause of morbidity and mortality in Behcet’s disease (BD) patients. Pulmonary arterial aneurysms and pulmonary artery thrombosis (PAT) are the most commonly observed lesions. Although deep vein thrombosis is common in patients with BD, pulmonary embolism is considered to be rare in BD patie...

Through technological innovations, patient cohorts can be examined from multiple views with high-dimensional, multiscale biomedical data to classify clinical phenotypes and predict outcomes. Here, we aim to present our approach for analyzing multimodal data using unsupervised and supervised sparse linear methods in a COVID-19 patient cohort. This p...

Background We aimed to compare the effectiveness of traditional Ventilator associated pneumonia (VAP) and Ventilator associated event (VAE) surveillance definitions in the determination of mechanical ventilator related infectious complications in patients who required invasive mechanical ventilation (MV) for COVID-19 associated respiratory insuffic...

Through technological innovations, patient cohorts can be examined from multiple views with high-dimensional, multiscale biomedical data to classify clinical phenotypes and predict outcomes. Here, we aim to present our approach for analyzing multimodal data using unsupervised and supervised sparse linear methods in a COVID-19 patient cohort. This p...

Objectives: Costovertebral (CV), costotransverse (CTr), sternoclavicular (SC), and manubriosternal (MS) joints are impacted in spondyloarthritis (SpA) patients; however, clinical aspects of these involvements require additional evaluation. Methods: A total of 281 SpA patients who had undergone chest computed tomography (CT) for any reason betwee...

Objectives: The rate of pleuroparenchymal involvement in the spondyloarthropathies (SpA) patients varies widely, from 0% to 85%. The most common is apical fibrobullous disease (AFLD). The aim of this study was to determine the incidence of AFLD and associated factors in SpA patients under and/or planned to start Biologic Disease Modifying Antirheu...

Purpose: The clinical management of high-risk lesions using image-guided biopsy is challenging. This study aimed to evaluate the rates at which such lesions were upgraded to malignancy and identify possible predictive factors for upgrading high-risk lesions. Methods: This retrospective multicenter analysis included 1.343 patients diagnosed with...

Background In spondyloarthritis (SpA) patients, costovertebral (CV) and costotransverse (CTr) joint are affected however these involvements are not routinely examined in clinical practice. Clinical characteristics of these involvements need further assessment. Objectives In this study, we aimed to determine the characteristics of CV and CTr joint...

Background Pulmonary rheumatoid nodule(RPN) is an serious extraarticular manifestation of rheumatoid arthritis (RA). The clinical features and activity of the RA, used DMARDs and the characteristics of the nodule may affect the progression of the RPN. [1] Objectives To identify the characteristics of the PRN and factors affecting its progression....

Coronavirus disease 2019 (COVID-19) is associated with pneumonia and has various pulmonary manifestations on computed tomography (CT). Although COVID-19 pneumonia is usually seen as bilateral predominantly peripheral ground-glass opacities with or without consolidation, it can present with atypical radiological findings and resemble the imaging fin...

Introduction: Stroke-associated pneumonia (SAP) is a significant cause of morbidity and mortality after stroke. Various factors, including dysphagia and stroke severity, are closely related to SAP risk; however, the contribution of the baseline pulmonary parenchymal status to this interplay is an understudied field. Herein, we evaluated the progno...

The term destroyed lung is now of historical importance and is not often used in everyday radiology practice. Although it refers to irreversible end-stage lung disease, it is important for radiologists to know this term and the imaging findings of the underlying diseases so that definitive treatments such as lung resection and transplantation can b...

Neoadjuvant chemotherapy is increasingly used for breast cancer due to its several benefits. Assessment of the response to neoadjuvant chemotherapy plays a key role in the management of the disease. Although magnetic resonance imaging is the most accurate method, evaluation of the response to neoadjuvant chemotherapy may be challenging especially i...

Background Radiological diagnosis of thoracic nerve diseases is difficult because they are rare and nerves cannot be seen directly on radiological images. The major nerves of the thorax can be listed as the phrenic, vagus, recurrent laryngeal, long thoracic nerve pairs, sympathetic chains, costal nerves, and brachial plexus. Diseases of thoracic ne...

Background The frequency of pulmonary rheumatoid nodules closely relates to the diagnostic modality and changes from <0.4% to 32%. Also, it is known that seropositive RA patients tend to have more extra-articular disease. Objectives We aimed to compare the disease and pulmonary rheumatoid nodule characteristics of seropositive and seronegative RA...

Background Costovertebral (CV), costotransverse (CTr), sternoclavicular (SC) and manubriosternal (MS) joint involvements may be in spondyloarthritis (SpA). However, the radiological and clinical characteristics of these involvements need further assessment. Objectives In this study, we aimed to determine the characteristics of CV, CTr, SC, and MS...

Background: COVID-19 associated pulmonary aspergillosis (CAPA) has been reported as an important cause of mortality in critically ill patients with an incidence rate ranging from 5% to 35% during the first and second pandemic waves. Objectives: We aimed to evaluate the incidence, risk factors for CAPA by a screening protocol, and outcome in the...

Interpretation differences between radiologists and diagnostic errors are significant issues in daily radiology practice. An awareness of errors and their underlying causes can potentially increase the diagnostic performance and reduce individual harm. The aim of this paper is to review both the classification of errors and the underlying biases. C...

Background Breast involvement of hematological malignancies is a very rare entity. Accurate diagnosis is essential for appropriate treatment. The aim of this study was to clarify the clinical and radiological findings of hematological malignancy breast involvement and to describe possible pitfalls in diagnosis. Results The images of 20 patients wi...

Congenital lung diseases in adults are rare diseases that can present with symptoms or be detected incidentally. Familiarity with the imaging features of different types of congenital lung diseases helps both in correct diagnosis and management of these diseases. Congenital lung diseases in adults are classified into three main categories as bronch...

This registry-based case-control study aimed to assess the association between asbestos deposits in the birthplace and/or residence and nonmalignant pleural findings, namely pleural plaques (PPs) and pleural thickening (PT), on chest CT scans. In total, 39,472 CT scans obtained over five years in a tertiary referral hospital in Ankara, Turkey, were...

Objective: To quantitatively evaluate computed tomography (CT) parameters of coronavirus disease 2019 (COVID-19) pneumonia an artificial intelligence (AI)-based software in different clinical severity groups during the disease course. Methods: From March 11 to April 15, 2020, 51 patients (age, 18-84 years; 28 men) diagnosed and hospitalized with...

Background: We aimed to analyze the usefulness of a reserved area for the admission of the patients' symptoms suggesting COVID-19 and compare the demographic and clinical characteristics of the patients with COVID-19 and without COVID-19 who were admitted to C1 during the first month of the COVID?19 outbreak in our hospital. Materials and methods...

Background Extra-articular manifestation (EAMs) definition is not clearly defined in psoriatic arthritis (PsA). Nail involvement, enthesitis, dactylitis has been widely studied however, data are needed on pulmonary involvement in PsA. Objectives We aimed to understand real-life results of lung involvement in PsA patients. Methods From the PsA coh...

Purpose: Triple-negative breast cancer (TNBC) has some distinctive features. The aim of the study was to compare clinical and breast magnetic resonance imaging (MRI) findings of TNBC with non-triple-negative breast cancer (nTNBC) in molecular subtypes such as ADC (apparent diffusion coefficient) values, T2-weighted (T2W) image intensity, shape, ma...

This study aimed to evaluate atrophy of the latissimus dorsi muscle (LDM) via computed tomography (CT) in patients who underwent mastectomy and axillary lymph node dissection (ALND). Secondary objectives were to investigate the relationship between the number of lymph nodes and muscle atrophy and to evaluate a possible correlation of muscle atrophy...

Background The aim of this study was to evaluate the magnetic resonance imaging (MRI) findings of invasive breast cancer in different histopathological types (invasive ductal carcinoma (IDC), invasive lobular carcinoma (ILC) and mixed ductal-lobular carcinoma (MDLC)) and different histological grades. Methods A retrospective review was made of 125...

Objectives: Rheumatoid arthritis (RA)-associated lung involvement is a cause of mortality. This study aimed to evaluate mortality rate and mortality-associated factors in RA patients with high-resolution computed tomography (HRCT)-proven lung involvement. Methods: Patients followed-up for RA between 2010 and 2018 were evaluated regarding HRCT-prove...

Male breast hosts various pathological conditions just like “female breast.” However, histo-anatomical diversities with female breast lead to many differences regarding the frequency and presentation of diseases, the radiologic appearance of lesions, the diagnostic algorithm, and malignity features. Radiological modalities may play an important rol...

Hydatid cyst caused by the larval form of Echinococcus is a worldwide zoonosis. The lungs and liver are the most common sites involved. While the lung parenchyma is the most common site within the thorax, it may develop in any extrapulmonary region including the pleural cavity, fissures, mediastinum, heart, vascular structures, chest wall, and diap...

Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has rapidly spread worldwide since December 2019. Although the reference diagnostic test is a real-time reverse transcription-polymerase chain reaction (RT-PCR), chest-computed tomography (CT) has been frequently used in diagnosis because of...

PurposeThe aim of this study was to evaluate visual and software-based quantitative assessment of parenchymal changes and normal lung parenchyma in patients with coronavirus disease 2019 (COVID-19) pneumonia. The secondary aim of the study was to compare the radiologic findings with clinical and laboratory data.Methods Patients with COVID-19 who un...

Objectives There is increasing evidence that thrombotic events occur in patients with coronavirus disease (COVID-19). We evaluated lung and kidney perfusion abnormalities in patients with COVID-19 by dual-energy computed tomography (DECT) and investigated the role of perfusion abnormalities on disease severity as a sign of microvascular obstruction...

Differential Diagnosis of Pulmonary Sarcoidosis Based Upon Imaging Findings

Imaging findings of smoking-related interstitial lung diseases

Objective: Lymphatic irradiation in breast cancer improves locoregional control and has been shown to decrease distant metastasis. However, irradiation also accelerates the formation of atherosclerosis and can cause stenosis, not only in the coronary arteries but also in the internal mammary artery (IMA). The aim of this study was to investigate t...

Background The frequency of pulmonary rheumatoid nodules closely relates to the diagnostic modality and changes from <0.4% to 32% [1]. However, data regarding pulmonary rheumatoid nodules in RA-related interstitial lung disease (RA-ILD) is scarce. Objectives The aim of this study was to describe the general features and localisation of pulmonary r...

Background Interstitial lung disease is an important cause of mortality and morbidity for RA. Lung computerized tomography (CT) is a valid method for the detection of interstitial lung disease (ILD) in rheumatoid arthritis (RA) patients. Besides, CT may have a role in the detection of progression in RA-ILD. Objectives To compare the clinical and r...

Objectives: There is increasing evidence of thrombotic events occurring in patients with coronavirus disease (COVID-19). We evaluated dual-energy computed tomography (DECT) findings, particularly lung and kidney perfusion, in non-intubated COVID-19 patients. Methods: Thirty-one COVID-19 patients who underwent pulmonary DECT angiography between Marc...

Errors and discrepancies may cause some unwanted outputs. Here is an awarded(Certificate of merit) poster about errors, discrepancies, and underlying bias in radiology.

Don't you want to know some commonly used medical devices and their correct location based on systemic classification?

Objective: Ultrasonography guided core needle biopsy is a real-time, inexpensive method with higher patient comfort. The aim of this study was to evaluate ultrasonography findings of microcalcifications without accompanying mass and also to investigate the accuracy of ultrasonography guided core needle biopsy results. Materials and Methods: The stu...

Objective: Benign fibroepithelial lesions (BFL) lesions of the breast are various and predominantly benign, although a few can be locally aggressive. Definitive diagnosis of some BFL can be challenging from core needle biopsy (CNB). Radiological findings can help guide the management of the lesions. The aim of this study was to investigate the acc...

Objective: The aim of this study was to evaluate the clinical, imaging and histopathological features of breast cancer in patients aged under 40 years of age. The relationship between radiological characteristics and histopathological features was also investigated. Materials and methods: The study included 131 patients aged under 40 years, diag...

Objective: Magnetic resonance imaging (MRI) and ultrasonography (US) are commonly used in the pre-surgery determination of tumor size and the follow-up of breast cancer patients treated with neoadjuvant chemotherapy (NAC). The aim of this study was to compare the efficiency of preoperative MRI and US in tumor size evaluation of patients with breas...

Learning objectives: To review nonmammary breast malignancies with radiopathological correlation. To recognize imaging features of “metastatic lesions to the breast” and “breast involvement by hematologic malignancies”. To distinguish nonmammary breast malignancies from primary breast lesions.

To review the reasons of thickening of the tracheal wall with a systematic approach. To be familiar with the imaging findings of the tracheal wall diseases. To be able to differentiate tracheal tumors from tumorlike conditions

: Introduction: Inguinal hernias can be seen in childhood approximately with a range between 0.8 and 4.4 %. In female patients, in 15% to 20% of cases there is an ovary with or without Fallopian tube in the inguinal hernia. Case Report: In this paper, a case of 6 months old female patient presented with ovary containing inguinal hernia and ovarian...

Objectives: The aim of this study was to evaluate any association between histological grade, molecular subtypes of breast cancer, and strain elastography, and to investigate whether microcalcification affects the stiffness of tumor in breast cancers with the same histological grade. Methods: Between April 2015 and March 2016, 94 lesions of 94 p...

The aim of this study was to investigate the differences of placental elasticity between intra-uterine growth restriction (IUGR) and normal pregnancies to show whether or not there is any association between histopathological changes and placental elasticity. Fifty-five human placentas were collected at delivery, including 25 with IUGR and 30 contr...

Background: Granulomatous mastitis (GM) is a rare inflammatory breast disease that may mimic the clinical characteristics and radiologic imaging findings of breast carcinoma. Considering the importance of making a correct diagnosis, careful radiologic evaluations and recognition of imaging features are necessary. Objectives: The aim of this stud...

Purpose: Cigarette smoking has been associated with increased occurrence of multiple sclerosis (MS), as well as clinical disability and disease progression in MS. We aimed to assess the effects of smoking on the white matter (WM) in patients with clinically isolated syndrome (CIS) using diffusion tensor imaging. Methods: Smoker patients with CIS...

The neutrophil-to-lymphocyte ratio (NLR) is clinically accepted as one of the markers of systemic inflammatory response. In breast cancer patients, NLR can be used as an important prognostic indicator of survival. In routine laboratory tests, the platelet-to- lymphocyte ratio (PLR) can also be examined besides the NLR. Although the effect on surviv...

Background: Arterial dissection is defined as the cleavage of the arterial wall by an intramural hematoma. Reports of dissection of the celiac and/or superior mesenteric artery are rare; as far as we know, only 24 cases of spontaneous isolated celiac trunk dissection, and 71 cases of spontaneous isolated superior mesenteric artery dissection have...

Smoking has been associated with an increased risk of developing multiple sclerosis, disease progression and clinical disability. We detected the effects of smoking on regional brain volumes and lesion load in patients with clinically isolated syndrome using quantitative magnetic resonance imaging. Smoker patients (n = 16), smoker healthy controls...

To determine effectiveness of coronary artery calcium score (CACS) alone and combined with Systematic Coronary Risk Evaluation (SCORE) in adult patients for significant coronary artery stenosis by using computed tomography coronary angiography (CTCA) as reference standard. Two thousand twenty-one patients with suspected coronary artery disease (CAD...

Pyelolymphatic backflow phenomenon, which is a subtype of pyelorenal backflow, is a rare condition that occurs during the acute phase of urinary obstruction. Pyelorenal backflow has already been described in humans with retrograde pyelography. Our report presents a rare case of pyelolyphatic backflow demonstrated by a computed tomography. A 67-year...

This retrospective study was designed to investigate the transcatheter mesenteric angiography of patients with gastrointestinal (GI) bleeding and to determine the most important variables that should be monitored in patients with GI bleeding prior to transcatheter arteriography. In this study, we evaluated the transcatheter mesenteric angiography r...