Feng Lin

Egis Technology · Product Development

Blood glucose has been demonstrated to serve as prognostic indicators in various malignancies. This study aimed to explore the relationship between fasting blood glucose (FBG) levels and the prognosis in patients with gastrointestinal stromal tumor (GIST) undergoing complete resection. Data were retrospectively collected from 256 patients with prim...

Fecal immunochemical test (FIT) is often used for preselection for colonoscopy, but FIT has nonoptimal sensitivity. Selection of study participant for colonoscopy based on the result of combining FIT with risk factors could improve the sensitivity of a screening program. We aimed to develop a risk prediction system of colorectal neoplasia among asy...

Rakicidins G-I (1–3), three new cyclic depsipeptides including a long aliphatic chain without terminal methyl branching were isolated from culture broth of Micromonospora chalcea FIM 02–523, along with rakicidin E (4). Their structures were elucidated by extensive NMR and HR-ESI-MS analyses. Compounds 1–4 were evaluated for their cytotoxic activiti...

Objective To explore the performance of a protocol combining fecal immunochemical test (FIT) and a high-risk factor questionnaire (HRFQ) for selecting patients requiring colonoscopy as part of a population-based colorectal cancer (CRC) screening program in China. Methods From 2015 to 2016, we conducted a CRC screening program for all residents age...

Nuclear receptor binding protein 1 (NRBP1) is a ubiquitously expressed and highly conserved pseudokinase that has important roles in cellular homoeostasis. Despite recent advances in understanding the biology of NRBP1, the role of NRBP1 and its underlying mechanism in colorectal cancer (CRC) have not been fully elucidated. In the present study, we...

The Music and Culture Center (MCC) building, located in Shanghai, is a unique structure with three cabins suspended under the main structure by steel cables. A specific design approach involving progressive failure analysis was essential due to the structural characteristics such as less redundancy and safety sensitivity. An analysis strategy based...

Ground vibration induced by the collapse of large-scale cooling towers in nuclear power plants (NPPs) has recently been realized as a potential secondary disaster to adjacent nuclear-related facilities with demands for vibration mitigation. The previous concept to design cooling towers and nuclear-related facilities operating in a containment as is...

Force transfer in misaligned columns in building structures can be implemented using overlapping column transfer assemblies. Two 1/6 scaled models of overlapping column transfer assemblies were tested to investigate their mechanical behavior under monotonic loadings. Both specimens were constructed using reinforced concrete and had an overlapping r...

Nuclear power plants under expansion and under construction in China are mostly located in coastal areas, which means they are at risk of suffering strong earthquakes and subsequent tsunamis. This paper presents a safety analysis for a new reinforced concrete containment vessel in such events. A finite element method based model was built, verified...

Drop-weight tests were conducted on 10 pairs of reinforced concrete cubic blocks with a side length of 250 mm to investigate their motion states during the impact process. The collision type was face-to-face collinear impact which was primary collision type in structural collapse due to natural or man-made hazards. Incident velocity and reinforceme...

An aircraft crashing into a nuclear containment vessel may induce a series of disasters related to containment capacity, including local penetration and perforation of the containment, intensive vibrations, and fire ignited after jet fuel leakage. A procedure was presented for investigation of structural capacity of the containment of the newly dev...

Six new 16-membered macrolides with a rare branched octose unit, aldgamycins J-O (1-6), along with two known compounds, swalpamycin B (7) and chalcomycin (8), were isolated from Streptomyces sp. HK-2006-1. Their structures were determined by detailed spectroscopic and X-ray crystallographic analysis. Natural products containing branched sugar units...

Two new isocoumarin derivatives, talaisocoumarins A (1) and B (2), and three new related metabolites, talaflavuols A-C (3-5) were isolated from the wetland soil-derived fungus Talaromyces Away BYD07-13. Their structures were elucidated by spectroscopic (NMR) and MS analyses. The absolute configurations of 1 and 2 were determined by CD and an Rh-2(O...

One new dihydroisocoumarin, pericocin A (1), one new chromone, pericocin B (2), and two new cc-pyrone derivatives, pericocins C-D (3-4), together with two known compounds, 3-(2-oxo-2H-pyran-6-yl)propanoic acid (5) and (E)-3-(2-oxo-2H-pyran-6-yBacrylic acid (6), were isolated from the culture of the endolichenic fungus Periconia sp.. Their structure...

Pericoterpenoid A (1), a new cadinane-type sesquiterpene, was isolated from an endolichenic fungal strain Periconia sp. (No. 19-4-2-1). Its structure was characterized by analyzing the spectroscopic data (IR, MS, 1D- and 2D-NMR). The antimicrobial activity against Escherichia coli, Staphylococcus aureus, Aspergillus niger, and Candida albicans was...

Four new α-pyrone derivatives, nodulisporipyrones A-D (1-4), were isolated from the extract of an endolichenic fungal strain Nodulisporium sp. (65-12-7-1) that was fermented with rice. The structures of 1-4 were elucidated by extensive spectroscopic analysis, and the absolute configurations were determined by modified Mosher's method and electronic...