Faten Mohamed Ibrahim

National Research Center, Egypt | NRC · Department of Medicinal Aromatic Plants Research

Background Quinoa seeds (Chenopodium quinoa Willd.) have gained interest due to their naturally occurring phytochemicals and antioxidants. They possess potent anticancer properties against human colorectal cancer. Methods and Results: Fatty acids in quinoa oil were studied using gas chromatography-mass spectrometry. Rats were used to test the acute...

Recently, hand sanitization has gained attention for preventing disease transmission. Many on-the-market convenient dermal sanitizers contain alcohol, which can be detrimental to the skin. Therefore, three nanoemulgel formulations (LN-F1, LN-F2, LN-F3) incorporating lemon peel extract (LE), and with various increasing concentrations of xanthan gum...

Grapefruit (GF) processing generates significant nutrient and economic losses due to the production of 50% by-products, primarily peels. GF peels are a rich and sustainable source of bioactive compounds (BCs), such as essential oils (EOs) and phenolic compounds. Thus, finding value-added solutions based on a circular economy is paramount. This rese...

The purpose of this study was to investigate the potential of pectin extracted from orange waste by acid hydrolysis and prepared Pectin/ hydroxyethyl cellulose (HEC)/ZnO nanoparticles (ZnO-NPs) biofilm for food packaging applications. The pectin/HEC/ZnO biofilms were prepared in an aqueous solution at room temperature using solvent casting method a...

Quinoa seeds (Chenopodium quinoa Willd.) have grown in interest due to their naturally occurring phytochemicals and antioxidants. It was stated that it has a powerful anticancer effect against human colorectal cancer. Gas chromatography-mass spectrometry was used to analyze the quinoa oil fatty acids. Sodium alginate was used as a loading agent to...

Citrus peels are an important by-product of citrus processing industries, but a large part is considered waste. There has been increased attention in the last five years on these industrial by-products, especially those containing residual essential oils (EOs). Lemon, orange, and mandarin peels from Egypt were subjected to hydro-distillation to obt...

Background The second most common cancer in the world is breast cancer. Chemotherapy is used to treat breast cancer, but instances of multidrug resistance, targets that are not selective, and physicochemical issues raise doubts about its efficacy. So, the exploration of chemopreventive agents from efficient natural sources has been required. The ch...

Background: Obesity is complicated to treat and is a significant risk factor for some health problems such as diabetes and cardiovascular disease. Since drug treatment of obesity induces many side effects and has little long-term efficacy, natural plant extracts have been suggested to use as an alternative for long-term weight control. Cyanidin 3-g...

Background The second most common cancer in the world is breast cancer. Chemotherapy is used to treat breast cancer, but instances of multidrug resistance, targets that are not selective, and physicochemical issues raise doubts about its efficacy. So, the exploration of chemopreventive agents from efficient natural sources has been required. The ch...

Background: Exopolysaccharides are extremely powerful molecules with a wide range of uses in pharmaceuticals due to their structural and compositional complexity. Marine microorganisms often produce bioactive substances with novel functions and structures because of their special living conditions. Polysaccharides from marine microorganisms are of...

Blood clotting has become one of the most dangerous side effects associated with Corona virus, as well as the high level of cholesterol and triglycerides in the blood. Therefore, it has become necessary to use medicinal plants that are biologically safe and containing anti-clotting compound. Feijoa sellowiana represents a prolific source diverse co...

The food industries are interested in developing functional products due to their popularity within nutritional and healthy circles. Functional fruit-based beverages represent one of the fast-growing markets due to the high concentrations of bioactive compounds (BCs), which can be health promoters. Hence, functional beverages based on citrus fruits...

Physalis peruviana is an edible fruit becoming of increasing economic interest for its nutritional and beneficial health effects that even several countries targeted its cultivation recently to fulfill export demands taking the advantage of its adaptable nature to different soil types. Despite previous reports on its chemical content, little or no...

Background Chia oil is high in omega-3 fatty acids, which have been linked to a lower risk of many diseases, including cancer. Oil encapsulation is a method that holds promise for maintaining oil content while enhancing solubility and stability. The purpose of this study is to prepare nanoencapsulated Chia oil and investigate its suppressive effect...

Topiramate has multiple pharmacological mechanisms that are efficient in treating epilepsy and migraine. Ginger has been established to have gingerols and shogaols that cause migraine relief. Moreover, Topiramate has many off-label uses. Thus, it was necessary to explore the possible neurotoxicity of Topiramate and the role of ginger oil in attenua...

Chia oil is high in omega-3 fatty acids, which have been linked to a lower risk of many diseases, including cancer. Oil encapsulation is a promising method for preserving oil content and improving solubility and stability. This study aims to prepare nano-encapsulated Chia oil and explore its suppressive role against chemically induced breast cancer...

Raphanus raphanistrum L. is an edible flowering plant that belongs to the Brassicaceae family and is also known as wild radish. Recently, it was reported as a sustainable source of bioactive compounds and nutrients. For comprehensive metabolites profiling of R. raphanistrum whole plant, three types of extracts; aqueous ethanol (AEE), dichloromethan...

Background: Topamax® ® has multiple pharmacological mechanisms that are efficient to treat epilepsy and migraine. Ginger has been demonstrated to have gingerols and shogaols compounds that proven to cross the blood-brain barrier causing migraine relief, implying that it is useful in the treatment of migraines. Moreover, Topamax has many off-label u...

Diabetes is a worldwide public health disease. Currently, the most effective way to treat diabetes is to mitigate postprandial hyperglycemia by inhibiting carbohydrate hydrolysis enzymes in the digestive system. Plant extracts are rich in bioactive compounds, which can be used in diabetes treatment. This study aims to evaluate the polyphenols conte...

Introduction: Obesity is the major pathogenesis of the non-alcoholic fatty liver disease (NAFLD). The combination of low-level laser therapy (LLLT) and Mediterranean diet (MD) is a new approach for improving liver function. Methods: 60 obese older adults (65-75 years old) with NAFLD were randomly assigned equally to two groups: a study group and a...

Introduction: Obesity is the major pathogenesis of non-alcoholic fatty liver disease (NAFLD). The combination of low-level laser therapy (LLLT) and Mediterranean diet (MD) is a new approach for improving liver function. Methods: 60 obese older adults (65-75 years old) with NAFLD were randomly assigned equally to two groups: a study group and a cont...

Acrylamide (ACR) has been previously associated with male sexual dysfunction and infertility. Eruca sativa (L.) (arugula or rocket) have been widely used in traditional remedies in Mediterranean region and western Asia and was known for its strong aphrodisiac effect since Roman times. The current study was designed to investigate LC/MS analysis of...

Alzheimer’s disease (AD) and Parkinson disease (PD) are notorious neurodegenerative diseases amongst the general population. Being age-associated diseases, the prevalence of AD and PD is forecasted to rapidly escalate with the progressive aging population of the world. These diseases are complex and multifactorial. Among the different events, amylo...

Vitex agnus-castus, is a famous botanical remedy and a nutritional supplement to manage a panoply of human ailments. The impact of V. agnus-castus fruits aqueous-alcoholic crude extract and its fractions were evaluated for possible in vitro antioxidant, anti-inflammatory, and in vivo antitumor efficacy. The inhibitory action of the tested extract a...

Myrtus communis L. (MC) family Myrtaceae, is cultivated in Egypt as an ornamental plant. The essential oil (EO) isolated from different parts of the plant reported for many pharmacological activities. Myrtus black and white (MB &MW) are two varieties of Myrtus diverse from each other in the color of berries; the EO was prepared from the fresh ae...

Background The multidrug resistance (MDR) of cancer cells is a major obstacle to cancer treatment. Glutathione S-transferase Pi (GSTP1-1) catalyzes the conjugation of glutathione with anticancer drugs and therefore reduces their efficacy. Phenolic compounds have the potential to inhibit GST P1-1 activity, which is a promising goal to overcome MDR a...

Nigella sativa L. is an annual herb of the Ranunculaceae family. The seeds called black cumin seed which contains 34–39% oil. Its oil has many purposes in traditional medicine and food industries. Black seed oil is a significant source of essential fatty acids, tocopherols, phytosterols, phenolics, essential oils, and other bioactive compounds. Thy...

Vegetable oils are characterized by their bioactive phytochemicals including fatty acids, tocols, and phenolic compounds. In the current study, turnip (Brassica rapa) oil was evaluated for its fatty acid profiles, tocol composition, and total phenolic content. The radical scavenging properties of oil against DPPH· and galvinoxyl radicals were also...

The target of this study was to estimate the efficacy of garden cress seed oil in the treatment of osteoporosis in rats. Seventy adult female Sprague-Dawley albino rats were used that were divided into seven groups (n-10/ group). Methotrexate (MTX) was subcutaneously injected (0.65 mg/kg) for two separate 5 days courses (5 days on/9 days off), to i...

The target of this study was to estimate the efficacy of garden cress seed oil in the treatment of osteoporosis in rats. Seventy adult female Sprague Dawley albino rats were used that were divided into seven groups (n-10/ group). Methotrexate (MTX) subcutaneously injected (0.65 mg/kg) for two separate 5 days courses (5 days on/9 days off), to induc...

Liver and kidney role in detoxification and drug metabolism increases the risk of their poisonous injury. Topiramate (TMP) is an effective popular migraine prophylaxis that is accepted for utilize in adults and teenagers. Therefore, the target of this research is to estimate the potential toxic effects of TMP on liver and kidney in male mice. Thirt...

This study is intended to assess the Satureja montana L. and Mentha piperita L. var. citrata antiradical potential and elucidate their molecular mechanisms underlying the cytotoxic induction in HepG2 cells. The total phenolic and flavonoids of the selected plants were determined. Their antioxidant activity was evaluated using 2, 2-diphenyl-1-picryl...

Sexual dysfunction in the epileptic patient is difficult to confirm whether it is ailment or therapy related. Antiepileptic drugs often use in reproductive age, through reproductive progress and maturation. On the other side, cold-pressed oils are rich in bioactive phytochemicals with health-promoting traits. The target of this work was to appraise...

Microalgae provide a wealthy natural resource of bioactive compounds, which have many biological activities. Monosodium glutamate is a food additive that acts either as food preservatives or as tastiness enhancer. It was confirmed that monosodium glutamate poses a serious responsibility in the pathogenesis of anovulatory infertility. Therefore, the...

Context: Cold-pressed oils (CPO) are commercially available in the market and characterized by their health-promoting properties. Objective: Clove oil (CLO), coriander seed oil (COO) and black cumin oil (BCO) were evaluated for their bioactive lipids. Pharmacological screening was performed to evaluate acute toxicity, anti-inflammatory and ulceroge...

In order to add a new species of medicinal and aromatic plants to be cultivated in Egypt for export we decided to study the plant of Nepeta cataria L, by identifying the best ways to increase the proportion of seed germination, vegetative measurements and identify productivity of essential oil. Seeds germination of Nepeta cataria L plant as affecte...

Egypt presents a distinctive example of the drought problem faced in some arid and semi-arid regions. Water deficiency which often linked with other major abiotic stress such heat stress, salinity stress, etc. so, it is considered as one of the main factors responsible for crop productivity reduction. Thus, water conserving is becoming a crucial co...

The idea of this study was carried out to investigate the link between nutritional supplements rich in antioxidants and fertility. Punica granatum and Citrus aurantium peel extracts effects on fertility were studied in New Zealand rabbit ducks. Study was conducted by investigation of semen physical characters, hormonal analysis, gene expression of...

Egypt presents a distinctive example of the drought problem faced in some arid and semi-arid regions. Water deficiency which often linked with other major abiotic stress such heat stress, salinity stress, etc. so, it is considered as one of the main factors responsible for crop productivity reduction. Thus, water conserving is becoming a crucial co...

Background: The traditional herbal, medicinal plants, drugs are used in treating many diseases. The herbal treatment commonly used in treating most type of ulcers. Different extracts of Illicium verum were investigated for their anti-gastro ulcerogenic effect on rats. Aims: Evaluation of Illicium verum extracts as anti-ulcerogenic agent in rat mode...

Compost can enhance water holding capacity and fertility of soil and thus increase soil water availability and nutrient uptake by plants, but it is not clear whether it can also improve the ability of plants to recover after salinity stress. Quinoa plant was grown in soil with or without compost either with foliar spray Nigella sativa extract (25 &...

Inflammation is a process involving multiple factors acting in a complex network, where a distinct cytokine cascade of pro-inflammatory and inflammatory mediators unfolds. Substantial levels of bioactive phytochemicals were found in cold-pressed oils (CPO). Objective: To evaluate the antiradical and anti-inflammatory potential of CPO including Nige...

Chlorella vulgaris (CH) and Spirulina platensis (SP) are microalgae being touted as functional foods with a number of health benefits. CH and SP have potent antioxidant activity and provoke a free radical scavenging enzyme system. The present study was sought to assess the potential protective activities of CH and SP aqueous extracts against MSG to...

Camelina sativa is an oilseed crop and known as gold of pleasure and false flax. It holds promise as a source of human food and animal feed products and it is considered as a new source of essential fatty acids, particularly n-3(omega-3) fatty acids. The seed of Camelina can contain more than 40 % oil, 90 % of which is made up of unsaturated fatty...

The adverse effect of cypermethrin on the liver and kidney of weanling female rats and the protective effect of ethanolic extract of grape pomace were investigated in the present study. Weanling female rats were given cypermethrin oral at a dose of 25 mg kg −1 body weight for 28 consecutive days. An additional two Cyp-trated groups received extract...

The objective of this study is to evaluate the safety of Moringa oleifer leaves aqueous extract and its role on fertility of New Zealand rabbit bucks. Two doses of Moringa oleifera leaves extract (200 and 400 mg/kg/day) were administrated to rabbit bucks via gavage for 21 days. Sildenafil citrate at dosage of 5mg/kg was used as reference drug. Liver...

Tulsi is medicinal plant has been successfully adapted, propagated and cultivated under Egyptian conditions. The plant is promoted in relieving sore throats, toothaches, colds, coughs, laryngitits, bronchitis, nasal congestion and inflammation of the mouth and throat. They have many biological activities such as antipyretic, anti-inflammatory and a...

Nutrition is a key factor for growth and development of plants. Among the main nutrients is calcium (Ca). Calcium, uptaken as Ca2+, is essential element for the growth of the plants and fruit development, and it is important in the resistance of the plants to diseases due to with base in the protection of the cell wall. Ca plays important biochemic...

Chemical analysis of the air dried flowering aerial parts of N. cataria showed moisture (6.2%); ash (7.9%); crude fiber (15.57%); crude protein (9.13%); crude lipid (4.88%) and carbohydrate (62.5%).Fixed oil extracted from the air dried flowering aerial parts of N. cataria contained lauric (3.7%); myristic (7.2%); palmitic (20.3%); stearic (18.6%);...

Camelina sativa is an oilseed crop and known as gold of pleasure and false flax. It holds promise as a source of human food and animal feed products and it is considered as a new source of essential fatty acids, particularly n-3(omega-3) fatty acids. The seed of Camelina can contain more than 40% oil, 90% of which is made up of unsaturated fatty ac...

Marrubium vulgare L. (white horehound) belongs to Lamiaceae family. The plant is formerly much esteemed in hepatic affections and in phthisism. This work was conducted to investigate hepatoprotective and therapeutic effects of Marrubium vulgare aqueous ethanolic and petroleum ether extracts on CCL 4 induced liver cell toxicity in mice. The aerial p...

Salvia has been used since ancient times in folk medicine and many pharmaceutical industries. Salvia langiera Poir herbs, growing wild in Egyptian desert, are among nine endemic wild species native to Egypt. The essential oil of Wild Egyptian Salvia langiera has not been previously investigated in Egypt. The aim of the present study was to assess t...

This research was performed to investigate in vitro the biological activities of successive as well as 70% ethanol extracts of Nepeta cataria on some biochemical parameters including oxidative markers and carbohydrate-hydrolysing enzyme activities (α-amylase, β-galactosidase and α-glucosidase). Powdered N. cataria and its successive extracts were s...

The present research is design to evaluate the pharmacological effects of successive as well as 70% ethanolic extracts of Nepeta cataria on some biochemical parameters in Streptozotocin diabetic rats compared to the currently used Glicalized drug. The investigated parameters included, glucose, insulin, carbohydrate hydrolyzing enzymes; α –amylase,...

Using the experience derived from a screening programme of all school-going children in the Al Ain District, United Arab Emirates, this article reports on a cost-effective model that can be used in other developing countries. The need for training child health and school professionals in identifying mental and developmental disorders is discussed.

Using the experience derived from a screening programme of all school-going children in the Al Ain District, United Arab Emirates, this article reports on a cost-effective model that can be used in other developing countries. The need for training child health and school professionals in identifying mental and developmental disorders is discussed.