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Mugla Üniversitesi · Faculty of Engineering

The major shortcoming of aqueous calcium phosphate suspensions used in biomedical applications is their unstable flow during delivery by mechanical means. In this study, microstructural changes and the resulting flow instabilities of aqueous β-TCP suspensions are demonstrated under both pressure-induced and drag-induced flow regimes and then remedi...

Over the past few decades, calcium phosphate cement has been used successfully for bone reconstruction applications. As percutaneous surgical methods have developed, there is an increased interest in calcium phosphate cement injection behavior. The aim of this study is to minimize percolation (liquid phase migration under pressure) and maximize inj...

In the last years, the precision and personalized medicine is pushing the biomedical research efforts towards the direction of implant surgery requiring only 1-step approach: this goal has been achieved after the introduction of resorbable implants. The resorbable prosthetic support is indicated for temporary prosthetic applications, such as bone f...

Direct Writing (DW), also known as Robocasting, is an extrusion-based layer-by-layer manufacturing technique suitable for manufacturing complex geometries. Different types of materials such as metals, composites, ceramics, biomaterials, and shape memory alloys can be used for DW. The simplicity and cost-efficiency of DW makes it convenient for diff...

Modification of the setting process of brushite cements by varying the concentration of ions that alter calcium phosphate crystallization kinetics, is known to enable control on the monetite conversion extent and the accompanying microporosity. This is useful because monetite serves as a suitable matrix in macroporous scaffolds due to its higher ph...

The effects, modes and method of preshearing

The flow behavior and injectability of calcium phosphate cements are outcomes of the complex interplay between time dependent processes of dissolution, nucleation and crystal growth. Their dependence on shear strains, frequencies and rates have been revealed by rheological investigation of the setting processes of a brushite cement under torsional...

Biomaterials utilized in biomedical applications are of various characteristics and cements are unique in their in situ, biomimetic formation ability. They present the most topographically complex surfaces that usually elicit a favorable cellular response for tissue regeneration. In addition their composition may provide an effective chemical gradi...

Calcium phosphate cements are osteoconductive biomaterials that are widely used for bone repair and regeneration applications, including spinal fusion, vertebroplasty, khyphoplasty, cranioplasty and periodontal surgeries. The flow and deformation behavior (rheology) and injectability of the calcium phosphate bone cements to the treatment site are g...

Brushite forming calcium phosphate cements receive growing interest in hard tissue scaffold applications due to their high surface area and high bioresorbability. The finer microstructure of monetite, the dehydrated form of brushite, has attracted attention for bone tissue engineering applications. The reduction in brushite content of the beta-tric...

Brushite forming calcium phosphate cements (CPCs) have received growing interest for scaffold applications due to their high surface area and high bioresorbability. The dehydrated form of brushite, monetite, has a finer microstructure with higher surface area, higher strength and bioresorbability comparable to brushite, making it a viable alternati...

In this study, the effect of activator ZnO and heating time at 190°C on foaming, gelation, and dehydrochlorination of poly(vinyl chloride) (PVC) plastisol was investigated. For this purpose, a PVC plastisol was prepared by mixing PVC, dioctyl phthalate (DOP), azodicarbonamide (ADC), ZnO, and the heat stabilizers calcium stearate (CaSt2) and zinc st...