Emilian Damian Popovici

Victor Babes University of Medicine and Pharmacy of Timisoara | UMFT · Discipline of Epidemiology

Purpose The COVID-19 pandemic has severely impacted healthcare workers, a professional category at risk of infection in both hospital and community settings. The aim of the study was to compare morbidity among hospital staff and that in general population, as well as the factors predicting non-vaccination and reinfection. Patients and Methods The...

Trichinellosis is a public health problem and an economic issue in porcine animal production and food safety. The aim of this retrospective study was to evaluate the current epidemiologic, laboratory, clinical and therapeutic aspects of human trichinellosis in Western Romania. We retrospectively investigated the medical records of patients hospital...

The rapid advancement in vaccine development represents a critical milestone that will help humanity tackle the COVID-19 pandemic. However, the success of these efforts is not guaranteed, as it relies on the outcomes of national and international vaccination strategies. In this article, we highlight some of the challenges that Romania will face and...

Toxoplasmosis is caused by a single-celled parasite called Toxoplasma gondii which is an obligate, intracellular, protozoan. T. gondii is found worldwide, being one of the most common parasites. Although these infections are usually asymptomatic, or associated with flu-like symptoms, occasionally they occur during the first few weeks following expo...

Purpose: This study shows the epidemiological profile of the first gastroenteritis outbreak of GII.P17 in the Romanian territory. An outbreak with such large amplitude in a European territory was previously undocumented. Patients and methods: Using a cross-sectional design, with the susceptible-infected-recovered (SIR) deterministic compartmenta...

The aim was to estimate the odds ratio and burden of disease from nontraumatic upper and lower-extremity amputations attributable to diabetes and skin disorders in Arad County, Romania, from 2014 to 2018. A descriptive epidemiological study was chosen by calculating disability-adjusted life years (DALY). Odds ratio for amputations in diabetic patie...

Introduction. Clostridium difficile infection (CDI) was previously considered a nosocomial infection associated with antibiotic exposure, but now is more present in the communities and is obviously associated with acid-suppressive therapies. CDIs are common both in hospitalized and ambulatory patients, in nursing homes residents, being initiated by...

The novel GII.P17-GII.17 norovirus genotype has been reported as cause of gastroenteritis outbreaks in China and Japan since the winter season 2014/15, replacing the pandemic strain GII.4 Sydney 2012. These emergent strains have also been sporadically reported on other continents than Asia. GII.P17-GII.17 isolates, similar to Kawasaki308 2015, were...

The recent emergence of Clostridium difficile infections has included this condition among top nosocomial infections, due to its incidence, complications and important fatality, as well as to significant economic costs. A prospective surveillance study of Clostridium difficile enterocolitis cases was performed in "Victor Babeş" Infectious Diseases...

Background: In the context of immunosuppression associated with other risk factors, HIV-infected patients develop various respiratory comorbidities. This study aims to assess the impact of active smoking and the frequnecy of respiratory infections in adult HIV-infected. Methods: The authors have retrospectively analyzed the hospital records of 38 s...

Background: The treatment with pegylated-Interferon (peg-IFN) in patients with chronic hepatitis C induces neutropenia, associated with multiple infections. This study aims to evaluate the frequency of respiratory infections and its relations with neutropenia in patients treated with peg-IFN. Methods: The Authors included in the study 64 patients w...

Carpathian Journal of Earth and Environmental Sciences, February 2011, Vol6, No 1,p. 5-12

With all benefits of highly active antiretroviral therapy (HAART) therapy in Human Immunodeficiency Virus (HIV)-infected patients, oral candidiasis (OC) remains a significant health problem in these patients. The aim of the study was to determine the impact of smoking on oral candidiasis in HIV patients. We retrospectively analysed a group of 84 HI...

Purpose Fragility hip fractures represent a major health and social burden. To date, there are no reports regarding mortality and factors that influence outcomes after osteoporotic hip fractures in Romania. Material and methods The electronic database of the largest healthcare provider in the western part of the country was searched for hip frac...

On a global scale, pathogenic contamination of drinking water poses the most significant health risk to humans. In order to meet the drinking water criteria the classic water treatment processes include: coagulation/decantation, filtration and disinfection. Chlorination is the most widely used technique for disinfection of drinking water, it determ...

Prostaglandin endoperoxide synthases, commonly referred as cyclooxygenases (cyclooxygenase-1 and cyclooxygenase-2), catalyze a key step in the synthesis of biologically active prostaglandins. Recently, a cyclooxygenase-1 variant protein, named cyclooxygenase-3 was discovered and characterized. The three cyclooxygenases (COX-1, COX-2, COX-3) isoenzy...

As a fundamental human right "sufficient, safe, acceptable, physically accessible and affordable water for personal and domestic uses" is vital for all. Drinking water must have a quality that promotes and protects public health, the safe water expressing the accordance to the maximum admissible limits of the relevant water parameters for human hea...

Estrogens represent risk factors for endocrine-related cancers and play also an important role in the development and progression of other malignancies. In order to analyze the associations between estrogen receptor gene alpha polymorphisms and cancers susceptibility, we genotyped six single nucleotide polymorphisms (SNPs) in 163 Caucasian cancer p...

Polymorphisms in estrogen receptor alpha gene (ESR1) have been previously associated with breast cancer risk; however, the results were not fully consistent. Our purpose was to study interactions between common genotypes in ESR1, breast cancer risk and tumor phenotypes. 6 ESR1 single nucleotide polymorphisms (SNPs) were genotyped in 103 breast canc...

Accurate genotyping of hepatitis C virus (HCV) has clinical implications for treatment orientation and epidemiological impact in tracing the contamination sources. The aim of the study was to compare a genotyping assay by restriction fragment length polymorphism (RFLP) in the HCV 5'untranslated region (5'UTR) with sequencing in the 5'untranslated a...

The present study aims to analyse the risk factors involvement in the cross infectious pathology determined by multiresistant Enterobacteriaceae, in hospitalised patients in the Intensive Care Unit at the County Emergency Clinical Hospital in Timişoara. We carried out a case-control study with 3 groups of adult inpatients--200 patients with no supe...