Elizabeth R. Drake

University of Tennessee | UTK · Department of Small Animal Clinical Sciences

Background Demodex gatoi is a contagious ectoparasite that causes pruritic dermatitis in otherwise healthy cats. The diagnosis of this mite can be difficult, and its prevalence is unknown. Objectives The goal of this study was to identify the prevalence of D. gatoi in a population of cats with no known previous exposure to treatments using real‐ti...

Background Testing for hyperadrenocorticism is commonly pursued in adult dogs with dermatological disease, and adrenocortical suppression has been well‐documented following the use of topical corticosteroids in otic preparations. An otic suspension that contains florfenicol, terbinafine and mometasone furoate, and lasts for 30 days after a single a...

Background Feline inflammatory aural polyps (IP) have been reported as solitary growths, yet bilateral polyps may occur more commonly than described previously. Objectives To identify the prevalence and risk factors associated with bilateral feline IP within a population of cats evaluated at a veterinary teaching hospital over a 10 year period. A...

Background Approved treatments for canine otitis externa are limited in variety and may contain ototoxic ingredients. With bacterial resistance an ongoing concern, it would be ideal if non‐ototoxic agents combined with antibiotics resulted in a synergistic effect, requiring lower antibiotic concentrations to treat infections. Evidence of synergism...

Background Schipperkes develop bilaterally symmetrical alopecia preceded by lightening of the hair coat not associated with systemic clinical signs. The alopecia is presumptively diagnosed as Alopecia X but has never been investigated. Hypothesis/Objectives The purpose of this study was to describe clinical features, histopathological and laborato...

A nine-year-old, male, neutered Tibetan terrier was evaluated for unilateral otitis externa associated with the history of a dog bite injury to the pinna five years prior. Examination findings of the left ear included severe inflammation, abundant purulent exudate and a polypoid mass, obscuring view of the horizontal ear canal and tympanic membrane...

Background: Dermatophilus congolensis is a facultative anaerobic actinomycete that causes papular to exudative dermatitis with crusting in horses. This organism is frequently implicated as a cause of pastern dermatitis, but few data are available validating the organism's association with this disease. Hypothesis/objectives: The aim of this stud...

Background: Cutaneous adverse food reaction (CAFR) is diagnosed by performing an elimination diet trial utilizing prescription or home-cooked diets followed by provocative challenge. Objectives: To report findings of PCR analysis of a prescription vegetarian diet (RCV) for undeclared proteins of animal origin, as well as to describe its utilizat...

Background: Mycoplasma spp. are commensal organisms found in association with the mucus membranes of all mammalian species and are implicated in bacterial infections of many different locations. Mycoplasma spp. as a primary pathogen associated with otitis media in cats has not been reported. Objectives: To describe three cats with Mycoplasma inf...

Background: Mycophenolate mofetil (MMF) is a lymphocytotoxic immunosuppressive agent used in human and companion animal medicine for the treatment of immune-mediated disease. Mycophenolate mofetil is reported to have reduced myelotoxicity and hepatotoxicity when compared to azathioprine. Objectives: It was hypothesized that treatment with MMF as...

Background N‐Acetylcysteine (NAC) has the potential to be a useful therapeutic agent for the treatment of otitis externa due to its antimicrobial and mucolytic properties, as well as its ability to disrupt bacterial biofilm. Hypothesis/Objectives To determine the antibacterial activity of NAC against common bacterial isolates associated with canin...

This report describes a dog that developed erythema multiforme in temporal association with administration of the sulphonamide-based anticonvulsant drug zonisamide. Similar adverse drug reactions have been associated with sulphonamide antimicrobial drugs. Caution should be exercised when prescribing this medication for dogs with known hypersensitiv...

In veterinary medicine, Staphylococcus schleiferi was previously assumed to be an inhabitant of carnivore skin, however, more recently, it has been repeatedly documented in the literature as both an inhabitant and as a pathogen. In order to determine the frequency of nasal carriage, and the methicillin susceptibility pattern of S. schleiferi from h...

Terbinafine is an allylamine antifungal prescribed for the treatment of mycoses in humans. It is increasingly being used in veterinary patients. The purpose of this study was to evaluate the pharmacokinetic properties of terbinafine in dogs after a single oral dose. Ten healthy adult dogs were included in the study. A single dose of terbinafine (30...

A 7-year-old-spayed female standard poodle dog presented to the Iowa State University Veterinary Teaching Hospital with an 8-day history of lethargy, left hind limb lameness, ptyalism and peripheral lymphadenomegaly. On physical examination, the dog was lethargic, febrile (40.5 degrees C) and had multifocal to coalescing erythematous papular to pus...

Dermatophytosis is a frustrating and difficult disease to treat. In single-patient environments, the infection is usually cleared with traditional therapeutic strategies, in multiple-patient environments (e.g., multiple household pets, shelters, pet stores, breeders), the infection can be cleared only if aggressive and global surveillance and treat...

Staphylococcus intermedius and, less commonly, Staphylococcus aureus have been associated with most cases of bacterial skin disease in the dog and cat. Recently published information suggests that newly reported Staphylococcus organisms as well as coagulase-negative Staphylococcus species should be considered in addition to S intermedius and S aure...

To determine the frequency of isolation and susceptibility patterns of Staphylococcus schleiferi from healthy dogs and dogs with otitis, pyoderma, or both that had or had not received antimicrobial treatment. Prospective study. 50 dogs. Dogs were allocated to 1 of 4 groups: healthy dogs (n=13), dogs without otitis but with pyoderma (10), dogs with...

To evaluate effects of trimethoprim-sulfamethoxazole (T/SMX) on thyroid function in dogs. 6 healthy euthyroid dogs. Dogs were administered T/SMX (14.1 to 16 mg/kg, PO, q 12 h) for 3 weeks. Blood was collected weekly for 6 weeks for determination of total thyroxine (TT4), free thyroxine (fT4), and canine thyroid-stimulating hormone (cTSH) concentrat...

Staphylococcal pyoderma is the most common skin disease in dogs. Approximately 80% of allergic dogs have a secondary bacterial infection at diagnosis. Canine pyoderma is caused almost exclusively by Staphylococcus intermedius. However, the increasing prevalence of Staphylococcus aureus infections and the emergence of a new species, Staphylococcus s...

To determine whether the stress of an ultrasonographic procedure would interfere with the suppressive effect of dexamethasone during a low-dose dexamethasone suppression test (LDDST) in healthy dogs. 6 clinically normal adult dogs. In phase 1, an LDDST was performed 5 times at weekly intervals in each dog. Serum samples were obtained 0, 2, 4, 6, an...