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Value creation in university-firm research collaborations: A matching approach

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University-based technological opportunities are often exploited through joint corporate and academic entrepreneurship activities such as university-industry research collaborations. This paper explores the partner attributes that drive the matching of academic scientists and firms involved in these relationships. The paper models the formation of firm-faculty partnership as an endogenous selection process driven by synergy between partners’ knowledge-creation capabilities. The main findings indicate that faculty-firm matching is multidimensional: firms and scientists complement each other in publishing capabilities but substitute each other in patenting skills. Furthermore, firms and scientists with specialized knowledge create more value by teaming with more knowledge-diversified partners. The paper contributes to the literature on university-industry knowledge transfer, and more generally, to the literature on alliance formation.
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Electronic copy available at: http://ssrn.com/abstract=1351904
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Value Creation in UniversityFirm Research Collaborations:
A Matching Approach
Denisa Mindruta
Assistant Professor of Strategy
HEC-Paris School of Management
1 rue de la Liberation
Jouy-en-Josas, 78350 France
mindruta@hec.fr
This version: February 2012
ABSTRACT
University-based technological opportunities are often exploited through joint corporate and
academic entrepreneurship activities such as universityindustry research collaborations.
This paper explores the partner attributes that drive the matching of academic scientists and
firms involved in these relationships. The paper models the formation of firmfaculty
partnership as an endogenous selection process driven by synergy between partners’
knowledge-creation capabilities. The main findings indicate that facultyfirm matching is
multidimensional: firms and scientists complement each other in publishing capabilities but
substitute each other in patenting skills. Furthermore, firms and scientists with specialized
knowledge create more value by teaming with more knowledge-diversified partners. The
paper contributes to the literature on universityindustry knowledge transfer, and more
generally, to the literature on alliance formation.
Keywords: Matching, Complementarity, Endogeneity, Value Creation,
universityindustry alliances
Electronic copy available at: http://ssrn.com/abstract=1351904
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INTRODUCTION
Universities have always been an important source of new knowledge, and long-standing
evidence shows that academic research has a significant impact on the productivity of private
sector R&D (e.g., Cohen, Nelson, and Walsh, 2002). Spillovers from published academic
research and informal collaboration are influential channels of knowledge transfer, but recent
studies suggest that firms also seek out new scientific knowledge and technological
opportunities by engaging in corporate entrepreneurship activities such as licensing academic
inventions and collaborative research (Thursby and Thursby, 2002). Of particular interest for
the management field is evidence showing that firms with direct research ties to universities
significantly increase their innovative performance (e.g., Cockburn and Henderson, 1998;
Zucker, Darby, and Armstrong, 2002; Belderbos, Carree, and Lokshin, 2004; Fabrizio, 2009).
While the economic benefits of collaboration are well documented in the literature, the
sources of value creation in universityindustry research alliances remain under-explored.
Much of the empirical work on alliances performance links an innovation output to an
indicator measuring the presence of these relationships, while a few studies go deeper to
examine the outcome of collaboration in relation to partner characteristics. This work
typically regresses performance on the observed attributes of firms, scientists, or universities.
However, this methodology is valid only when (1) all attributes of the partners that influence
performance are included in the model and measured without errors, or when (2) alliance
formation is a random process. The first condition is hardly ever satisfied in empirical
settings. In strategy research, where great emphasis is placed on strategic, i.e., non-random,
choices (Shaver, 1998), the second condition is particularly problematic.
At the core of this study is the idea that partnership formation is a strategic decision. If
partner choice is guided by preferences about whom to ally with, and motivated by the
expectation that collaboration with certain partners will lead to superior performance, the
Electronic copy available at: http://ssrn.com/abstract=1351904
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process of partner selection is neither random nor independent of performance considerations.
Put succinctly, if there are incentives whereby certain types of partners end up allying (i.e.,
they ‘match’ according to certain preferences), then partner attributes must be endogenous
choice variables in regressing alliance performance on the characteristics of the partners. As a
result, empirical models that do not account for the partner selection process will produce
biased estimates and even skewed normative conclusions. These econometric concerns have
been acknowledged in the alliance literature, but matching as a cause of endogeneity remains
poorly understood.
To illustrate the importance of matching and its implications, consider Zucker et al.’s
(1998, 2002) finding that partnerships with ‘star’ university scientists have a higher impact on
firms’ innovation performance than partnerships with non-star faculty. By concluding that the
differential productivity of firmstar alliances is due to the added value professors contribute
to the innovation process, these studies suggest that firms aspiring to increase performance
should pursue research ties with top faculty. This conclusion raises several questions. Firms
may prefer teaming-up with ‘stars’, but are such collaborations equally attractive to
scientists? Could scientists be equally productive no matter what firm or firms they
collaborate with? Further, if success is a result of partnering with ‘stars’, why would firms
partner with ‘non-star’ faculty?
The existing literature has also accumulated compelling evidence that scientists value
firms based on multiple factors, such as the strength of internal research, technological
expertise, and organizational culture. As this paper will show, if scientists care about the
quality of the firm, and firms care about scientists’ research excellence, the interaction of
these preferences will lead to a sorting of partners across alliances, causing ‘better’ scientists
to work with ‘better’ firms. The endogeneity arises when top faculty team with firms whose
qualities reinforce their expertise and effort in innovation (i.e., scientists and firms match on
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complementary attributes) but the regression model does not include all relevant firmquality
dimensions. The error term then captures the effect of the omitted firm attributes and
becomes correlated with faculty research status, overestimating star scientists’ contribution to
innovation. Conversely, when partners match on attributes that act as substitutes in
innovation, the omitted attributes of one party will bias downward the estimates of the
observed characteristics of the other party.1
The above example illustrates a large class of situations in which partner choice affects
performance estimates. Researchers typically attempt to control for the confounding effects
of partner selection through instrumental variables or experimental design. In contrast, this
paper argues that facultyfirm partnering reveals important information about the sources of
value creation driving cross-organizational alliances and, ultimately, their differential success
in innovation. It introduces a theoretical model and a methodology that examine alliance
formation as an endogenous matching process in which firms and scientists strategically
select each other based on attributes that are important for knowledge-creation. The model
predicts positive (i.e., top-down) sorting of scientists and firms on attributes that are
complements in the innovation process, and negative sorting on attributes that are substitutes.
I apply this approach to a proprietary database that contains the complete set of 447
discovery-type collaborations between professors at a top U.S. medical school and their
industry partners during 1995-2004. Employing recent developments in econometrics, I
estimate the model using a maximum score estimator (Fox, 2010). Parameters are identified
based on mathematical inequalities that compare the output created by observed and
1 In general, the bias depends on the relationship between the included and omitted variables and the impact of
the omitted variables on performance. In the example discussed here, the omitted variables measuring firms of
higher quality have, most likely, a positive effect on innovation. Thus, the direction of the bias rests on the
relationship between the omitted firm variables and scientists’ status. In the case of complementarity between
firms and top scientists, the omitted attributes of the firms will be positively related with scientists’ status,
leading to an upward bias impact of ‘stars’ on performance. In the case of substitution, attributes of the partners
will be negatively related, and the impact of ‘stars’ on performance will be biased downward.
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counterfactual matches. These inequalities are derived from the equilibrium outcome of the
matching model, which predicts that when partner choice occurs under rivalry constraints, the
observed matches should create (weakly) higher value than counterfactual partnerships. The
results show that firmfaculty research alliances create more value when partners
complement each other in publishing capabilities and substitute each other for lack of
patenting capabilities. There is also evidence of complementarity between knowledge-
diversified and knowledge-specialized partners.
This paper extends the prior literature in several ways. The theoretical approach, rooted in
the management theories that recognize heterogeneity in capabilities as a central feature of
firms (e.g., Helfat et al., 2007), builds upon the conceptualization of two-sided matching
markets to include strategic aspects of partner choice (Mortensen, 1988). Unlike previous
work that focused on firms or universities, this paper considers alliance formation from the
perspective of both partners. Furthermore, the analysis of partner choice goes beyond
considerations of mutual attractiveness at the dyad-level and takes into account the
competition between participants on the same side of the market to ally with the most
desirable exchange partners on the other side of the market.
This approach generalizes previous findings and explains empirical regularities that other
models fail to clarify. While prior literature has emphasized the value-added contribution of
star faculty to the innovativeness of partner firms, this paper draws attention to partner
sorting in the market for research. The multidimensional sorting model captures the
differences between participants’ preferences and ability to attract partners more than other
simpler, univariate models. Within this perspective, firm collaboration with non-star faculty
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is not a simple story of top-down sorting but a more nuanced reflection of heterogeneity in
preferences and synergy types (complementarity vs. substitution) in innovation.2
THEORETICAL BACKGROUND
This paper examines how new knowledge is created when actors deliberately form new ties
across organizations or sectors. Thus, although linkages between universities and industry
can take multiple forms, here I focus specifically on formal research collaboration between
university scientists and firms intended for scientific discovery.
Main Concepts
To key concepts are complementarity and substitutability. The mathematical definitions of
these terms stipulate that two inputs are complements in production if the cross-partial
derivative of the production function with respect to the two inputs is positive, and substitutes
if the cross-partial derivative is negative.3
For this study, the research alliance ‘production function’ can be framed as a knowledge
output whose inputs are partner attributes. Indeed, the objective of a research alliance is to
create value (in the form of new knowledge or cross-learning among partners) beyond what
scientists and firms would yield separately. The joint output depends on the combination of
partner attributes, which may include strengths building upon strengths or the strengths of
one partner substituting for the other partner’s shortcomings. Conceptualizing the production
function in this way implies that two attributes are complements in knowledge creation if
having a higher level of one raises the return from having a higher level of the other.
2 For example, the finding of negative sorting on patenting skills predicts, ceteris paribus, that partnerships
between firms with higher patenting activity and ‘non-star’ patenting scientists (i.e. scientists with fewer or no
patents) are better matches than alliances between partners that both patent a lot. Thus, these partnerships are not
the result of firms not having access to ‘star patenting’ scientists, but they reflect preferences for partner choice
on dimensions that are substitutes in innovation.
3 These terms have been used with many other meanings in the strategy literature (e.g., complementarity has
been equated with compatibility, non- similarity, or non-overlap), but this paper employs the formal economic
definition of these concepts. The formal definition has been applied to the study of organizational decisions
related to firm boundaries (Parmigiani and Mitchell, 2009), the relationship among various organizational
practices (Milgrom and Roberts, 1995), and among firm internal resources and R&D alliances (Arora and
Gambardella, 1994; Cassiman and Veugelers, 2006).
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Conversely, two attributes are substitutes if having a higher level of one decreases the
marginal value of having a higher level of the other.
The term market for research refers collectively to all transactions in which professors
and firms agree upon joint research activities leading to the creation of new knowledge and
technologies, without changing organizational boundaries or asset ownership. This study also
advances the idea that the market for research is a two-sided matching market. Two-sidedness
indicates that agents involved in a transaction belong to one of two disjoint sets (here, firms
and universities). By contrast, in a typical commodity market, an agent might be a buyer at
some price and a seller at another price. Matching reflects the bilateral nature of exchange.
For example, in labor markets, an employee works for a firm, and the firm employs the
worker. As Roth and Sotomayor (1990:1) explain, this is in contrast with the markets for
goods, ‘in which someone may come to market with a truck full of wheat, and return home
with a new tractor, even though the buyer of wheat doesn’t sell tractors, and the seller of
tractors didn’t buy any wheat.’ The concept of a two-sided matching market captures the
theoretical underpinnings of the markets involving exchanges of heterogeneous and
indivisible goods (Mortensen, 1988). In this regard, universityindustry partnerships are a
typical example. The inputs each partner brings to the relationship are highly differentiated:
the expertise of university scientists is not a commodity, and neither are the capabilities of
individual firms. Moreover, in this particular context, an exchange involves an indivisible
bundle of distinctive characteristics that parties on one side of the market offer to parties on
the other side. These two aspectsheterogeneity and indivisibilitylead to an important
theoretical distinction. While the identity of agents who trade in commodity markets does not
matter, it is important to understand whether agents in matching markets trade with the right
partners. The critical question in these markets is who trades with whom.
A matching model of alliance formation
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The following three features of universityindustry alliances define the matching process:
(1) University-industry research alliances are voluntary relationships that form with the
expectation of mutual gains. One of the professors interviewed for this paper described his
decision to collaborate with industry in the following way:
[…] because I only have so much time, I’m not going to spend my time on something
that I don’t think is going to be productive. And I certainly will not have students and
people in my group spend time on something that’s not productive. So, I think that’s
where it comes down to. There is the mutual interest and then there have to be mutual
benefits. And, if those aren’t there, then there is no reason to do it.
Likewise, as Stephan notes: ‘firms can ill afford to fund research that has little promise of
eventually relating to the company’s objectives’ (1996: 1211). Most commonly, research
projects involving university partners go through a competitive selection process along with
internal projects. Thus, it is reasonable to believe that only projects with justifiable benefits to
the firm will be approved.
(2) The value of innovation generated through collaboration is determined, at least in
expectation, by the identity of the university scientists and firms involved in a relationship.
Consequently, both professors and firms have preferences about with whom they collaborate.
In discovery-type collaborations, preferences are driven by the belief that joint work with
partners of a certain type (such as those with high research productivity and expertise in a
particular scientific field) will have a higher probability of generating new knowledge.
(3) Alliance partners are restricted in the number of collaborations they can undertake at
one time. On the academic side, time constraints are one of the main reasons for a careful
screening of the number and quality of industry partners. Moreover, research contracts often
impose confidentiality conditions that prevent scientists from collaborating with multiple
companies simultaneously (Kenney, 1986). Firms have a better ability to manage multiple
contracts with external parties, up to the point where over-embeddedness becomes a liability
(Uzzi, 1996). The management of alliances is a complex process facing numerous challenges,
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such as managing coordination among partners and creating an appropriate organizational
structure for inter-partner learning and knowledge transfer. These constraints limit the
number of simultaneous alliances firms can pursue.
Taken together, preferences for potential partners and restrictions on the number of
collaborations suggest that, in the market for research, agents on each side of the market will
compete to ally with the most desirable partner on the other side of the market. While prior
literature has examined inter-firm competition in innovation races, and scientists’ competition
for funding and academic prestige (Stern, 1995), firms’ (respectively, scientists’) competition
for teaming up with the ‘best’ alliance partner has been largely ignored. This type of rivalry is
extremely important in matching markets, where ‘transactions’ involve differentiated bundles
of indivisible resources in limited supply.
From a theory standpoint, firmscientist alliance formation belongs to a more general
class of models (known as assignment games) that address the formation of voluntary
partnerships among complementary agents under conditions of rivalry (Mortensen, 1988).4
Economists have typically studied matching in marriage and labor markets. More recently,
scholars have begun to apply these models to the study of various business relationships,
including those between firms and IPO underwriters (Fernando, Gatchev, and Spindt, 2005),
start-ups and VC investors (Sorensen, 2007), buyer-supplier contracting (Fox, 2009; Chatain,
2010), or the assignment of resources to firms (Lippman and Rumelt, 2003).
4 An outcome in assignment games consists of an assignment (i.e., the identity of the matching parties) and a
vector of payoffs (i.e., a division of surplus between the members of a matched pair). The equilibrium concept is
that of pairwise stability, a notion that captures the idea that none of the partners to a match have an incentive to
separate and team with other partners. Optimality means that un-matched agents could not form a partnership
and make one better off without making the other worse off. Assignment games study questions such as which
partnerships will form given the agents’ preferences and the rules governing the market. These models are
appropriate for studying the ex ante process of partnership formation. In contrast, prisoners’ dilemma and
assurance games are appropriate for studying the ex post dynamics of alliances, where partners decide how
much to contribute to joint activity (Agarwal, Croson, and Mahoney, 2010).
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Matching theory explains what happens when all features of alliance formation
voluntary collaboration, two-sided decision-making, and competition for better partnersare
considered in interaction. From this perspective, partnership formation is a two-sided process.
Each agent on one side of the market evaluates, and is simultaneously evaluated by, potential
partners on the other side of the market. At the dyad level, and in isolation from the rest of
the market, the decision rule is simple: a partnership occurs when both partners expect that
collaborating will create more value than remaining single. However, under rivalry for
partners and preferences on both sides, synergy at the dyad level is no longer a sufficient
condition for an alliance if any of the partners could create a higher surplus with another
agent on the other side of the market. At the market level, dyad-level decisions interact to
constrain each other. On the one hand, the likelihood that an agent (firm or scientist) teams
with his or her preferred partner is influenced by the existence of other agents on the same
side of the market wishing to ally with the same partner. On the other hand, the likelihood of
teaming with the preferred partner is also influenced by the alternative opportunities the
partner might have to forego by entering a particular deal. In short, the decision of two
individual agents to collaborate depends not only upon their preferences, but also on their
effective choice set, which is constrained by the decisions made by all other agents in the
market. Ultimately, it is the interaction of preferences and competition at the market level that
leads to the final matching.
The core theoretical properties of matching, in which the attributes of the partners are
complements or substitutes in the match production function, were introduced to the literature
by Becker (1973).5 Becker’s results lead to the following prediction: Ceteris paribus, if two
inputs or attributes (capabilities of a scientist and a firm, respectively) are complements in
5 Becker considers the unidimensional case (one attribute on each side) and shows that if two inputs/attributes
are complements (substitutes) in production, then positive (negative) assortative matching is stable and optimal.
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knowledge-production, in equilibrium, firms and scientists scoring highest on these
dimensions will work together, leaving firms and scientists scoring second to select each
other, and so forth until the least-endowed agents select each other. Conversely, if two
attributes are substitutes, then firms (scientists) scoring high on one attribute will match with
scientists (firms) scoring low on the other attribute.6
The set of theorems proven by Becker (1973) constitute the basis for the empirical
matching model. Drawing from innovation literature, I examine the matching of scientists
and firms along three key dimensions in collaborative research: publishing capability,
patenting capability, and the degree of knowledge specialization (focused versus broad).
Hypotheses
As most fields of modern science, biomedical research considered in this study is
simultaneously motivated by scientific interest and considerations of usefulness and
applications (Stephan, 2010). In this context (typically referred to as Pasteur’s Quadrant)
discoveries have dual scientific and applied/commercial value, providing opportunities for
inventors to disclose their ideas through scientific publications, patented inventions, or both
(Murray and Stern, 2007). As I discuss below, the choice of disclosure regime sends differing
signals about inventors’ research abilities and motivations (Hicks, 1995; Anton and Yao,
2003), and plays an important role in facilitating knowledge exchanges among academics and
firms (Hellmann, 2007; Gans and Stern, 2010).
The norms of ‘Open Science’ reward priority in advancing novel ideas and provide
incentives for full disclosure of scientific findings in the public domain. The scientific merit
of a discovery is decided by the research community through the peer-review process and
citations. Publishing is the hallmark of academia, but articles published by corporations have
6 Some partnerships might look ‘suboptimal’ from the perspective of the dyad, such as, for example, alliances
between two less-endowed agents (as in the case of positive assortative matching), or alliances between one
highly endowed agent and one less-endowed agent (as in the case of negative assortative matching). However,
these partnerships are ‘optimal’ when all linkages in the market are taken into account.
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increased significantly in the last decades (Stephan, 2010). A salient motivation for corporate
publishing is firms’ desire to participate in knowledge exchanges within the broader scientific
community (Hicks, 1995; Henderson and Cockburn, 1998). These publications serve two key
roles. First, they indicate a firm’s willingness to abide by the norms of reciprocation and full
information disclosure (Murray, 2011). Second, they signal a firm’s research quality
(including the existence of tacit knowledge and unpublishable resources) and thus, provide
the necessary ‘credentials’ for the firm to find exchange partners in the scientific community
(Hicks, 1995).
The norms of ‘Commercial Science’ reward priority in producing ideas that are novel,
useful and non-obvious. The choice of patent disclosure regime indicates that the inventor
seeks to secure monopoly rights on ideas and will follow the logic of commercial practices in
exchanges involving these ideas (Murray, 2011). Like publishing, patenting has a strong
signaling value (Anton and Yao, 2003) and is practiced both in the industry and academia.
Patents signal to other market participants the strength of a firm’s proprietary knowledge and
technical expertise in a field (Ahuja, 2000). In academia, patents indicate that a scientist’s
ideas have useful marketable applications, and are often perceived as a ‘symbol of
commercial savvy’ (Murray, 2011).
Building on this literature, I refer to publishing and patenting capabilities to denote the
ways firms and university scientists deploy their knowledge capital to signal expertise and
preferences for the ‘open’, respectively, ‘commercial science’ regime.7 8 By patenting or
7 Patenting and publishing take different roles in different markets (labor, capital, product, or ideas market) and
the variation in patent and publication records of firms and faculty reflects more than differences in capabilities.
For example, firms might patent aggressively when they engage in ‘patent blocking’ and patent races, or seek to
improve their bargaining power (e.g. Hall and Ziedonis, 2001).In academia, patenting might be driven by
strategic and reputational calculations, as well as social influences (Murray, 2011). I focus on knowledge-related
interpretations because participants in the market for research use observable patent and publication outputs to
make inferences about potential partners’ expertise.
8 To my knowledge, Murray and co-authors (e.g. Gans, Murray and Stern (2008) and Murray (2011)) were the
first to systematically use the terms ‘open’ vs. ‘commercial science’ to emphasize that the main difference
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publishing in a narrower or a broader territory of the knowledge space, firms and scientists
also convey the breadth of their knowledge base. Specialization implies that an innovator’s
knowledge is concentrated in a narrow territory of the knowledge space, and diversity or
‘breadth’ of knowledge indicates familiarity with a broad range of scientific or technological
components.
Patenting and publishing capabilities. A number of findings in the innovation literature are
consistent with the idea that corporate publishing is driven by firms’ desire to participate in
networks of scientific knowledge. In particular, firms that provide ‘pro-publication’
incentives and promote scientists based on their scientific standing are more likely to
collaborate with universities and to rely on academic research in their innovation activities
(Cockburn and Henderson, 1998). In contrast with prior studies that looked exclusively at the
relationship between corporate publishing and firms’ propensity and degree of collaboration
with universities, I focus here on the quality of firms and faculty involved in these
relationships. Specifically, if publications signal scientific merit, I propose to examine the
extent to which firmfaculty alliances are driven by complementarity between partners’
publishing capabilities, such that firms and faculty select each other assortatively based on
their ability to generate high-quality scientific work. Survey studies reinforce the idea that
firms aim to partner with professors with outstanding scientific record (Blumenthal et al.,
1986). Particularly in basic research collaboration, firms perceive professors’ research quality
as being more important than their geographic proximity or other factors (Mansfield and Lee,
1996; Audretsch and Stephan, 1996). Preliminary interviews for this study also indicated that
faculty value firms with superior records of publication. Thus, I propose to test:
Hypothesis 1: Ceteris paribus, firms’ and university scientists’ publication
capabilities are complements in value creation.
between publishing and patenting lies neither in the type of knowledge disclosed (basic vs. applied), nor in the
locus of production (academia vs. industry), but rather in the institutional norms of the two disclosure regimes.
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A long line of research in the innovation literature views academic science and
technological innovation as complementary and co-evolving. Numerous examples of key
discoveries corroborate the idea that technological development happens faster in areas with
strong science, while scientific progress emerges as a response to the challenges posed by
new technologies (Nelson, 2004). Furthermore, large-scale empirical studies done at high-
levels of aggregation have found a complementary relationship between public and industrial
R&D (David, Hall, and Toole, 2004). Scholars have also argued that due to the research cost
structure and the nature of incentives in universities and firms, it is more appropriate to have
the earlier stages of a research process done by universities, and the later, more applied and
more commercially viable innovation stages, in the industry (Aghion, Dewatripont, and Stein,
2008; Lacetera, 2009). These arguments suggest that alliances between faculty and firms are
driven by partners’ motivation to build on each other’s strengths in basic and applied
research. Thus, professors with a better record of scientific publications should be more
productive when teaming with firms with a better record of patenting, and vice-versa. Very
few studies exist at the alliance level, but those that do tend to support this perspective.
Orsenigo (1989) argues that, in the early years of the biotechnology industry, prominent
scientists preferred to collaborate with firms with higher number of patents. Studying a
broader range of industries in the mid 1990s, Mansfield and Lee (1996) found that
universityindustry collaboration was driven by the synergy between professors’ research
and firms’ efforts to create new products and processes. I therefore propose the following
hypothesis:
Hypothesis 2: Ceteris paribus, firms’ patenting capabilities and university
scientists’ publication capabilities are complements in value creation.
Prior literature tells us little about whether the relationship between the patenting
capabilities of faculty and firms are complements or substitutes in innovation. Recent work
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has identified a variety of individual and contextual factors that prompt professors to disclose
inventions and become further involved in their commercial development (Bercovitz and
Feldman, 2008; Stuart and Ding, 2006). However, although university professors might
occasionally disclose inventions in an attempt to seize immediate opportunities (Azoulay,
Ding, and Stuart, 2007), they need to build a track record of disclosures to credibly signal
expertise in converting scientific ideas to useful, marketable applications. For example,
Elfenbein (2007) showed that professors with a higher patenting reputation were more likely
to have their inventions licensed (although not necessarily for higher proceeds) than first-time
patentees.
A question of interest here is which firms are better positioned to harness professors’
patenting expertise? Two opposite scenarios are conceivable. On the one hand, firms with
superior patenting capabilities could contribute with technological skills and resources,
accelerating scientists’ inventions to commercialization. If scientists interested in the
commercial prospects of their ideas find collaboration with these firms valuable, we should
observe the following relationship:
Hypothesis 3a: Ceteris paribus, patenting capabilities of firms and scientists are
complements in value creation.
On the other hand, firms with a better in-house stock of patents also face higher
opportunity costs from working on inventions generated externally, particularly when those
inventions are in early stages, as is typical with inventions originating from universities
(Jensen and Thursby, 2001). On the contrary, firms with relatively lower technical capital
have lower opportunity costs from working on external ideas, and are more willing to take the
risks and exert the effort necessary to develop early-stage inventions (Lowe, 2001). I argue
that these aspects might be important for university scientists interested in the commercial
prospects of their ideas. The more technologically astute the scientist is, the more likely it is
that the research done with external partners is close to the scientist’s core agenda, and the
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more likely it is that the project’s success depends more on the scientist’s knowledge than on
his partner’s patenting skills. Under this scenario, we should observe collaboration between
professors with patenting expertise and firms with a shorter history of patenting.
A substitution relationship between partners’ patenting capabilities is only credible if the
parallel story is credible, too: that scientists with lower or no patenting skills will team-up
with firms with higher patenting capabilities. Indeed, for a professor with little experience in
capitalizing on the technological opportunities of scientific research, partnering with a firm
with higher expertise in patenting makes it possible to learn how early-stage ideas develop
into marketable innovations. Conversely, firms with an established patenting record are well
positioned to utilize scientific information towards more applied goals (Arora and
Gambardella, 1994). By deciding to do joint research with universities, these firms
effectively ‘buy an option’ in early stage research ideas that might later be commercializable.
For these firms with high patenting capabilities, it is less important that a prospective faculty
partner has patenting expertise. Thus,
Hypothesis 3b: Ceteris paribus, firms’ and university scientists’ patenting
capabilities are substitutes in value creation.
Knowledge breadth and specialization. Knowledge attributesbreadth and
specializationrepresent another set of potential sources of complementarities in research.
From the perspective of a party endowed with a diversified knowledge base, there is value in
partnering with a specialized external collaborator who can fill particular knowledge gaps.
Equally, a specialized agent will seek to ally with a more diversified external partner who
will envision new applications of the agent’s knowledge. While it is difficult to construct
irrefutable arguments against alternative combinations (between two broad or two specialized
partners, for example), numerous arguments suggest such combinations are less likely to
systematically drive the formation of firmscientist alliances. The rationale behind this
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assertion stems from the mechanisms through which breadth and specialization contribute to
the discovery process.
Consider firms with a diversified knowledge base. Their innovation performance stems
from their ability to capitalize on economies of scope from internal know-how and external
knowledge spillovers (Henderson and Cockburn, 1996). However, capabilities and resource
allocation priorities that enhance the development of breadth tend to conflict with those
required to develop depth (Wang and Tunzelmann, 2000). Diversification enables firms to
absorb and recombine outside know-how. Thus, firms keep up with the latest advances in a
field through alliances with specialized suppliers rather than through internal development
(Brusoni, Prencipe, and Pavitt, 2001).
Likewise, for a specialized university scientist (i.e., an ‘expert’ in a field), teaming with a
firm with a broader knowledge base constitutes a productive opportunity. Because diversified
firms already have mechanisms to internalize focused scientific information, professors’
interactions with diversified firms will require less effort. More importantly, formal work on
downsides of specialization has shown that reliance on multi-disciplinary teamwork helps
innovators with narrower expertise overcome the limitations of specialization (Jones, 2009).
Thus, exposure to diverse knowledge through teamwork or alliances tends to benefit
specialized inventors. However, assembling teams and capitalizing on diverse expertise can
be compromised by communication and coordination costs (Dahlin, Weingart, and Hinds,
2005). Faced with the trade-off between forming a partnership with multiple specialized
partners and a firm with a diverse array of knowledge, narrowly specialized scientists more
likely prefer the latter. These arguments imply cross-fertilization in innovation between
specialized scientists and firms with a diverse knowledge base. Hence:
Hypothesis 4a: Ceteris paribus, a complementarity relationship exists between firms
with a diversified knowledge base and university scientists with
focused expertise.
18
The complementarity between specialized firms and faculty with broad expertise becomes
evident when we examine these agents’ motivations for entering a research alliance. To
reduce the risk of technological exhaustion, specialized firms must pursue various boundary-
spanning activities (Rosenkopf and Almeida, 2003). Prior work has shown that building
alliances and relying on university research are methods of exploration (Bercovitz and
Feldman, 2007). Here, I propose that specialized firms have higher chances of successful
exploration when they partner with scientists whose expertise is broad rather than narrowly
specialized. This argument builds on prior research showing that scientific knowledge
increases the rate of invention by: (a) helping innovators identify useful directions of search,
(b) preventing them from wasting time with dead-ends, and (c) encouraging them in the face
of failure (Fleming and Sorenson, 2004). The returns from working with broader partners will
be higher when at least the first two mechanisms are considered. A partner with broader
expertise provides immediate access to multiple potentially relevant pieces of information.
This enables firms to become aware of possible linkages among various knowledge domains
and helps them more rapidly identify ways to leverage their knowledge. In addition, broader
scientists can deploy a larger set of information-processing filters, which in turn reduce the
uncertainty around possible applications of firms’ knowledge and eliminate inefficient
experimentation (Nelson, 2004).
I also conjecture that broader scientists are attracted to collaborations with specialist firms
who could enrich the scientist’s understanding of a particular scientific area. Working with
diversified firms is less likely to bring higher benefits to these scientists. Diversified firms
and scientists excel at recombination and new knowledge integration, and, if one alliance
partner possesses such skills, it is less necessary for the other partner to contribute the same
skill set. As noted before, potential benefits from increasing expertise diversity are subject to
diminishing returns. Thus, I propose:
19
Hypothesis 4b: Ceteris paribus, a complementarity relationship exists between
specialized firms and university scientists with broader expertise.
DATA AND METHOD
Because research contracts between firms and scientists are typically considered confidential
by both parties, prior researchers have used co-authorship as a proxy for collaboration.
However, many joint contracts do not result in co-authorship; co-authorship may also be a
result of informal ties between scientists. I overcame these problems by using first-hand
information from the Grants and Contracts Office of a top-ranked, private U.S. medical
school located on the East Coast. The sample contains the full set of facultyindustry
research contracts from 1995 (the earliest date for which this information was available) until
2004. The office released the following information: the name of the principal investigator,
the name of the firm, the project title, the start and end date of the contract, and the award
(contract) money. I supplemented this primary information with numerous secondary sources
detailed in the ‘variables’ section.
This empirical context is suitable for studying research collaboration between faculty and
firms for multiple reasons. Medical schools have a long history of collaboration with
industry, and research done in medical domains has been shown to have a strong impact on
industrial R&D (Cohen et al., 2002). Professors in medical schools patent more and are more
involved in technology transfer than professors in other fields equally important for the
private sector. The medical school studied here began collecting systematic data on research
contracts much earlier than other universities, allowing me to study a larger sample of
collaborations over a longer time span. Furthermore, all contracts in the sample reflect a clear
intent to generate innovation (i.e., they are referred to as discovery-type collaborations).
The sample consists of 447 contracts between 238 firms and 217 professors. The number
of contracts per year varied from 32 to 54. Almost 25 percent of the scientists and firms
collaborated with more than one partner during the observed decade, but there were no
20
instances of multiple scientists (or firms) working simultaneously with a firm (scientist) on
the same project. This data aspect implies a ‘one-to-one’ matching of firms and scientists.9
Variables
I collected firms’ stock of publications during a ten-year window (up to the collaboration
date) and scientists’ life-time publications from the ISI Science Citation Index. I chose a ten-
year window to allow a sufficiently long time for firms’ publication output to translate into
reputational effects. I weighted all publications by the number of citations they received in
the Web of Science database (as of April 2010). As is typical in innovation studies, I applied
a yearly depreciation rate of 10 percent.
I collected firms’ and scientists’ patents over a six-year window prior to the contract time.
I controlled for the variation in patent quality by weighting patents by citations received as of
June 2010, with a 10 percent annual depreciation rate.10
I measured the breadth of a firm’s knowledge base using an entropy index of
diversification based on the distribution of a firm’s patents in technology domains defined by
the inventive IPCR patent classes. The formula for this index is: ))/1ln(*(
1
N
ii ff , where N
represents the total number of technological domains (here, inventive IPCR) in which a firm
has been patenting and fi represents the fraction of patents in ith category. The index takes
higher values as firm knowledge becomes more diversified.
9Both the theory and the estimation method can be used to study ‘one-to-many’ and ‘many-to-many’ matching.
The assumption here is that projects are independent. Thus, treating alliance formation as ‘one-to-one matching’
is a better model for the current data and not the result of theoretical or methodological constraints. In contrast, a
‘one-to-many matching’ would imply, for example, that one firm collaborates with multiple scientists on the
same project. In this case, the choice of a particular professor is dependent on the choice of other faculty, and
the production function needs to be modified to include this aspect. There are no instances of such
collaborations in my sample. For a typical example of ‘many-to-many matching’, see Fox (2008).
10 Corporate publications and patents were aggregated at parent level after carefully considering the corporate
structure of the firm during the relevant time window. I took into account mergers and acquisitions, divestitures,
and name changes. I also performed several sensitivity analyses, and the final results are very similar even if I
use an alternative time window for patents (e.g., five or four years) or publications (e.g., nine or eight years).
21
The knowledge-diversification index of the academic scientists is similarly defined,
but technological domains were replaced with scientific domains. I identified the scientific
domains from the MEDLINE database of the National Library of Medicine (NLM). NLM
specialists classify each article according to a scheme known as the Medical Subject
Headings (MESH) thesaurus. The classification of articles based on the MESH thesaurus
insures consistency in classifying scientists’ expertise. The MESH thesaurus has a
hierarchical structure composed of descriptors (main headings), qualifiers (subheadings), and
Supplementary Concept Records. Descriptors indicate the main themes discussed in the
article, and qualifiers indicate a specific aspect of the descriptor. I treated a combination of
MESH descriptors and MESH qualifiers as constituting a scientific domain.11
Controls I included several control variables that might influence partner choice and the
matching of firms and scientists. Firm size (measured by the number of employees), as an
indicator of resources, and firm age (years since founding), as an indicator of experience, are
likely to play a role in alliance formation. I also included the size of the lab (measured by the
number of people associated with the principal investigator’s lab) and academic age (the
number of years since the scientist obtained her highest degree). I controlled for scientists’
academic titles by adding dummy variables for associate professor, full professor, and
chairman/chief (the excluded category was assistant professor). In a robustness checks
analysis, I also included a dummy variable for biotechnology firms (the excluded categories
were pharmaceutical firms and a small number of medical device firms). Table 1 describes
variables and their sources. Table 2 explains the relationship between variables and
hypotheses.
11 For example, ‘Coronary vessels’ and ‘Cardiac surgical procedures’ are descriptors, while ‘Injuries’ and
‘Adverse effects’ are subheadings. Accordingly, the combinations ‘Coronary vessels/injuries’ and ‘Cardiac
Surgical Procedures / adverse effects’ represent two different subject areas. I eliminated all MESH categories
that do not reflect substantive scientific information (e.g. the type of research support, the publication format,
the geographic location, etc.) The complete list of descriptors can be accessed from the NLM.
22
[Insert Table 1 here]
[Insert Table 2 here]
Model specification and estimation
The challenge in estimating a matching model arises from the fact that partner choice
depends on all other relationships formed in the market. Thus, there are as many endogenous
variables as the observed matches. When alliances are treated as independent decisions, as in
standard discrete-choice models, the choice probability that an agent chooses a particular
partner can be factored into a product of low-dimensional integrals. In a matching situation,
the choice probability is a multidimensional integral over the joint density of error terms. The
dimension of this integral is equal to all possible arrangements of pairings in the market. For
example, in one-to-one matching involving 100 agents on each side, the dimension is 100! =
9.33 * 1015. Integrating over such a high-dimensional integral is currently not feasible.
To overcome these problems, I estimated the model using a semi-parametric estimator
developed by Fox (2010), which generalizes Becker (1973)’s unidimensional analysis to the
multidimensional case. The estimator is semi-parametric in the sense that it requires the
specification of a production function but does not impose a distribution on the error terms.
The method relies on a property known as the ‘local production maximization’, which Fox
(2010) proved is satisfied whenever the observed matches are the equilibrium outcome of an
assignment game. The local production maximization condition states that the output created
by any two observed matches is greater than the output created by counterfactual matches
formed from an exchange of partners. 12
12Although the existence and the uniqueness of the equilibrium in one-to-one matching games are well known, a
general analytical solution for characterizing the matching of agents with multidimensional attributes does not
exist in the literature. However, because the local production maximization is a necessary condition, the
estimator does not require computing an equilibrium solution to a matching game (Fox, 2010).
23
To illustrate how the method works, I denote by (F, S) a firmscientist pair in the sample,
and by g (F, S |β) the output (or surplus) created by the pair working together. The
production function that describes the match output takes the following form:
g (F, S |β)= β [XF *YS] + εSF (1)
where XF represents the vector of firms’ characteristics, YS the vector of scientists’
characteristics, εSF is the error term, and β is the vector of parameters to be estimated.
I consider that each of the 10 years in the sample represents a separate matching market.
For any two observed collaborations in a market, (Fi, Si) and (Fj, Sj), the corresponding
match output is g (Fi, Si |β) and, respectively, g (Fj, Sj |β). The counterfactual pairings are
obtained by switching partners such that Fi pairs with Sj to generate g (Fi, Sj |β) and Fj pairs
with Si to generate g (Fj, Si |β). The local production maximization implies that the following
inequality is true:
g (Fi, Si |β) +g (Fj, Sj |β) > g (Fi, Sj |β) +g (Fj, Si |β) (2)
The estimation procedure requires checking the local production maximization inequality
(1) for all 9,996 possible combinations of firm-scientist in the sample and the corresponding
counterfactuals. The parameters β are estimated by choosing the values that predict the
highest number of inequalities. Formally, the estimator maximizes the following objective
function:
Q(β) = * ,
where 1[ . ] denotes an indicator function which takes a value of 1 if the expression between
parentheses is true and 0 otherwise, Nh is the number of pairs in each individual market, and
h is a market index that here takes values from 1 to 10. 13
13 Note that the production function g (F, S |β) and the objective function Q(β) contain only interaction terms.
Production levels are also affected by the ‘main’ effects of XF and YS. However, the main effects cancel out in
the local maximization inequality (2). This property is consistent with the theoretical model, which asserts that
24
Each time the inequality (2) holds for a trial guess of the vector of parameters β, the score
of correct prediction increases by 1. The vector of parameters that yields the highest score of
correct predictions Q(β) provides a consistent estimator of the parameters β (Fox, 2010).
Note that adding a constant to the match output or multiplying it by a positive constant
will not affect the inequality (2). To take account of this aspect, the scale of the production
function must be normalized. I normalized the scale of the match output by setting to |1| the
coefficient β0 of the interaction term between two control variables: the size of the firm and
the lab size. 14 As Stephan (2010) points out, biomedical research relies increasingly on
sophisticated equipment and expensive material, which makes access to resources a necessary
condition for doing research in this field. In this context, a partner of larger size is more
valuable because it provides the possibility to undertake more complex research projects at
lower costs. In addition, a larger partner gives access to a broader network of people. I
conjectured that these aspects are important on both sides of the market. Thus, I chose the
interaction term |1|*FirmSize * LabSize to play the role of a ‘benchmark’ relationship,
relative to which I assessed the magnitude of the other relationships in the model. Following
a standard approach in the literature (e.g. Fox, 2009; Yang, Shi, Goldfarb, 2009), I ran
separate analyses for both +1 and 1 and I chose the sign that produced a higher value for the
objective function.
Hypothesis testing requires sub-sampling, a procedure that involves random sampling
without replacement and generating 95% confidence intervals for the estimated coefficients.
The reported confidence intervals were obtained from 200 random samples. The appendix
offers a more detailed description of the method.
matching is driven entirely by the interaction between partners’ attributes, while the ‘un-interacted’
characteristics cancel out because all potential partners value them equally.
14 All choice models impose a scale normalization of the utility function. Typically, the variance of the error
terms is set to a number chosen for convenience (e.g. the variance of the error terms is set to π2/ 6 in logit
models and to 1 in probit models). A standard way to normalize the scale in a maximum score estimator is to set
one coefficient to be equal to |1|.
25
RESULTS AND DISCUSSION
Table 3 provides the descriptive statistics and the correlation matrix. All of the key variables
have a substantial amount of variation. While prior research has focused on the contribution
of public research for start-ups and large, established firms (see Cohen et al., 2002), current
data show that universityindustry research collaborations involve firms that vary
considerably in age, size, and publication and patenting activity. On average, firms in the
sample published 230 publications and applied for 82 patents every year.15 Faculty published
on average 3.8 articles yearly and 70 articles over a career. Faculty in the top decile of the
distribution had more than seven patents, and 42 percent of contracts involved a scientist with
at least one patent application. The sample mean is equal to two faculty patents.
[Insert Table 3 here]
Because the interpretation of results is not meaningful when variables have different units
of measurement and differ greatly in scale magnitude, I standardized the variables using the
z-score transformation. Table 4 presents the estimated sign of the baseline and the estimated
values of β coefficients and their 95% confidence intervals.
[Insert Table 4 here]
Model 1 focused on the relationships predicted in H1-H4, controlling for several other
determinants of matching. As the correlation matrix showed, larger firms tended to generate
patents and publications of better quality. Thus, I controlled for potential confounding effects
of firm size by including the interaction terms between firm size and scientists’ capabilities.
Likewise, I controlled for lab size effects by interacting this variable with firms’ capabilities.
Because experience and seniority in an industry/ field are likely to matter in alliance
formation, I added in the model the interaction between firm age and academic age.
15 To make the comparison easier, I discuss here yearly averages, while Table 3 reports the statistics for the
stock of patents and publications as described in Table 1.
26
However, the variable academic age might reflect both the experience and the academic
status of the scientist. To disentangle these effects, I included separately the interaction
between firm age and scientists’ title. Lastly, to separate the effects of firm age from those of
firm size, I also interacted firm size with scientists’ age and title variables.
The results of the multivariate matching analysis strongly corroborate the relationships
hypothesized in H1, H3b, H4a, and H4b. As predicted in H1, firms’ and scientists’ publishing
capabilities are complements in innovation. As conjectured in H3b, there is a negative
relationship between partners’ patenting capabilities, consistent with the idea that patenting
capabilities are substitutes. The fourth interaction term shows that firms and scientists whose
research is concentrated in fewer scientific domains create more value by teaming up with
more knowledge-diversified partners. An unexpected result is the negative relationship
between firms’ patenting capabilities and professors’ publishing capabilities, while H2
predicted a positive relationship. This finding echoes Gittelman and Kogut (2003), who found
that biotechnology firms’ high-impact patents did not build on important scientific papers, a
result the authors attributed to the fact that valuable inventions and valuable scientific
knowledge follow different and conflicting evolutionary selection ‘logics’. While Gittelman
and Kogut’s study was based on patents and publications by biotechnology firms, their
arguments offer a possible explanation for the negative relationship between firms with
higher stock of important patents and faculty with a higher stock of important publications.
However, I cannot rule out a simpler argument that the operationalization of variables did not
capture all relevant aspects for the division of innovation labor between firms and scientists.
The inclusion of various controls in the equation revealed interesting aspects of matching.
All other things being equal, faculty with a higher stock of important patents create higher
synergies by partnering with firms of smaller size. This result reinforces the arguments
behind the finding that scientists’ and firms’ patenting capabilities are substitutes. Contrarily,
27
professors with a better publication record create higher synergies with more resourceful
firms. This finding echoes a longstanding view in the literature that universityindustry
collaboration is driven by scientists’ need to obtain resources from industry partners.
However, this result also shows that, all else equal, access to firms with more resources is
given to (and more valued by) prominent scientists.
We can also observe a negative relationship between lab size and firms’ publishing
capabilities, suggesting that firms with higher publication capabilities get more rewards from
collaborating with individual scientists or smaller teams. Likewise, it shows that firms’
publishing capabilities are more important for smaller labs than for larger ones.
The relationship between firm age and academic age is negative, an indication that more
experienced partners are substitutes for less experienced partners. Other interesting effects
can be observed when the role of firm experience (age) and resources (size) are examined in
interaction with faculty academic title.16 In particular, both larger firms and younger firms
create higher synergies by partnering with professors of high standing, such as chairmen and
chiefs of various divisions. Thus, both large and startup firms compete for higher status
faculty. These findings suggest that on the one hand, professors that can manage larger-scale
projects match with firms that can provide an appropriate level of resources; on the other
hand, faculty with higher standing in administration match with younger firms, which are
riskier but potentially, more rewarding partners.
The estimated sign of the baseline is positive, indicating complementarity between
partners’ resources. In terms of economic significance, the baseline represents the marginal
effect on the innovation output created by increasing the size of the firm and the lab by one
standard deviation. In Model (1), the baseline effect on the production function was
16 A model where I included the relationship between firm age, respectively, firm size with a variable measuring
the academic title on a scale from 1 (assistant professor) to 4 (chairman or chief) did not produce significant
coefficients, which is not surprising given that age/size and academic title interact in a non-monotonic way.
28
normalized to +1 and it represents the scale to which we can interpret the magnitude of other
coefficients. The results show that increasing the publication capabilities of both partners by
one unit (i.e., one standard deviation in the stock of quality-adjusted publications), has a nine-
times-higher effect on the innovation output than the baseline. Further, in absolute value, the
marginal impact of a one-standard-deviation change in partners’ patenting capabilities is 15
times more important than the baseline, and the marginal effect of a unit change in
knowledge-diversity is four times more important. 17
As well as being significant, the variables measuring partners’ capabilities explain a fair
amount of the variation in the data. Model (1) predicts 74% of inequalities.18 For comparison,
Model (2) shows the results of an equation that has only control variables; few coefficients
were significant and the model explained 59% inequalities. Model (3) contained all
relationships except those predicted by the main hypotheses and explained 61% inequalities.
Robustness checks
I performed several robustness checks to test the sensitivity of results to alternative model
specifications and variable transformations. Models (4) and (5) test whether the main
relationships predicted in H1 to H4 remain robust when firm age, respectively, industry
effects are taken into account. In relative terms, the impact of the main relationships on the
alliance output is smaller in these specifications, but previous results remain significant and
of the same sign. The analysis in Model (4) shows that firm age does not play an important
role when considered in combination with scientists’ publishing and patenting capabilities,
17 Because of the substitution relationship, the impact is positive in absolute terms when one unit increase in
patenting capabilities of one partner is associated with one unit decrease in patenting capabilities of the other
partner. The same reasoning applies for knowledge diversity: in absolute terms, one unit increase in knowledge
diversity on one side of the market, together with one unit decrease in knowledge diversity on the other side of
the market has a four times higher impact on the alliance output than the baseline.
18 In a market with k agents on each side, the maximum number of inequalities predicted by a random
configuration where k-2 pairs are identical to ones in the ‘true’ model is: (k-2) (k-3)/k(k-1). For the 10 markets
in the sample, we obtain (by multiplying the corresponding number of inequalities for each market) .386 or
38.6% inequalities. However, the expected value for such arrangement to occur is equal to (k-2)(k-3)/k(k-
1)*(1/(k!-1)), which is close to zero in the data.
29
but younger firms and more knowledge-diversified scientists create higher synergies together.
In Model (5), the results remain robust to the inclusion of a dummy variable for
biotechnology firms. Interestingly, scientists with higher patenting capabilities and those with
a more diversified knowledge base create higher synergies by collaborating with
biotechnology firms. However, the relationship between faculty publishing capabilities and
biotech dummy is not significant. Finally, Models (6) and (7) in Table 4 show that results of
the empirical test are robust to the log transformation of variables.19
Limitations and future research
The results of the matching analysis presented here are based on several assumptions. The
model discounts search costs (e.g., the cost of finding a partner), the potential initial
uncertainty about the match value (e.g., adverse selection), and other types of market
frictions, such as institutional policies of technology transfer that might impede the formation
of public-private partnerships. These factors should be taken into account for a more
comprehensive approach to match formation. For example, with high search costs,
geographical location might be an important consideration in partner choice. Because
collaboration contracts in this paper are from one university, all scientists in the sample are
equally located from the firms’ point of view. Data from more universities would allow us to
examine the role of geography in universityindustry partnerships. Likewise, data from
universities with different technology-transfer policies would allow researchers to determine
if frictions created by technology transfer terms (e.g. rigid rules on intellectual property
rights) might preclude some matches from happening.
19 A small constant of 0.001 was added before logging to insure that values equal to zero remained in the
estimation. The constant shifts the distribution to the right and the log transformation minimizes the importance
of extreme values. The baseline now represents the marginal effect on the innovation output generated by
increasing the size of the firm and the lab size by 1%. Because of the log transformation, the interpretation of
coefficients is in terms of ‘percentage change’. For example, Model (7) in Table 4 indicates that relative to 1%
increase in firm size and lab size, a 1% increase in publishing capabilities of both partners (measured on the
new scale) yields a 4% increase in the alliance output. Additional analyses (available upon request) show that
results are not driven by the presence in the sample of firms and scientists without publications or patents.
30
This paper was based on the premise that the objective of a research alliance is to
generate new knowledge. Future work could examine if considerations other than research
productivity, such as perceptions of social status or affiliation with a particular social
network, provide additional explanatory power or change the understanding of matching
observed here.
The theoretical model presented in this paper addressed questions related to value
creation and abstracted away the costs of governance, value appropriation, and partnership
evolution. The connection between matching and these important aspects of alliances creates
an interesting opportunity for additional research.
Contribution to the literature of university-industry knowledge transfer
This study made a first step toward unpacking the dimensions of firmscientist matching in
research collaboration. The empirical analysis showed that research partners complement
each other in publishing capabilities, but substitute each other in patenting capabilities.
Knowledge diversity also matters in partner choice, as shown by the complementary
relationship between knowledge-specialization and knowledge-diversification.
These findings are interesting both in the context of universityindustry knowledge
transfer and, more generally, for the literature on alliance partner selection. The results
corroborate previous work that found a performance-enhancing effect for firms connected
with university professors with an outstanding research record. However, this study
contributes to a better understanding of the underlying causes of these effects. While previous
work has focused the value-added contribution of ‘stars’ in the innovation process, I show
that, through the ex-ante matching process, ‘star’ scientists team-up with firms that also have
outstanding publication records. Further, although publishing capabilities are important in the
market for research, I show that firmscientist alliance formation is driven by a more
31
complex set of considerations, notably, by anti-assortative matching based on patenting
capabilities.
Contribution to the literature on alliance formation
Despite the importance of matching in partner choice, theoretical and empirical work in this
area is in an early stage. This paper argued that the drivers of alliance performance cannot be
fully understood without taking into account the matching process that precedes the
formation of research alliances, and it provided a rigorous approach for examining
partnership formation. The paper introduced a theoretical model that explicitly deals with the
endogeneity problem created by the self-selection of ties in specific partnerships. The model
demonstrated that anticipating synergistic gains and competing to ally with better partners
leads to sorting in the market, which, in turn, explains why certain firmscientist alliances
create more value and enjoy higher innovation performance. The empirical analysis followed
the theoretical model closely and focused on identifying the underlying sorting patterns
created by complementarity and substitutability of partner attributes. Both the theoretical
framework and the methodology can be applied to settings other than knowledge creation.
ACKNOWLEDGEMENTS
This paper has significantly benefited from comments and suggestions by the members of my dissertation
committee, Rajshree Agarwal, David Audretsch, Janet Bercovitz, Glenn Hoetker and Joseph Mahoney. I am
also thankful to the editor Will Mitchell and three anonymous referees for their suggestions for improvement
during the reviewing process. Several people have provided useful comments at various stages of this project, in
particular, Gautam Ahuja, Thomas Astebro, Pierre Azoulay, Dan Elfenbein, Alfonso Gambardella, Bernard
Garrette, Shane Greenstein, Nicola Lacetera, Kristina McElheran, Deepak Somaya and Scott Stern. I am grateful
to Janet Bercovitz for generously sharing data for this project. The Ewing Marion Kauffman Foundation and the
Academy for Entrepreneurial Leadership at the University of Illinois at Urbana-Champaign have provided
invaluable financial support. Any remaining errors are my own.
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35
Table 1.Variable Definition
Firms
Size
(FIRM SIZE)
Number of employees at contract year.
Source: Factiva; Corporate Affiliations; Thomson One
Publishing
Capabilities
(FIRM PUB CAP)
Ten-year stock of publications weighted by the number of citations (as of April 2010) and
a 10% yearly depreciation rate.
Source: ISI Web of Science *, combined with Corporate Affiliations to account for
organizational structure at the publication time
Note that ISI is the only collection of medical journals that contains information on
authors’ institutional affiliations during the sample timeframe. However, ISI provides this
information only for the first ten authors. Thus, this measure constitutes an accurate, albeit
conservative record of firms’ publications.
Patenting
Capabilities
(FIRM PAT CAP)
Six-year stock of patents weighted by citations (as of June 2010) and a 10% yearly
depreciation rate.
Source: Delphion combined with Corporate Affiliations to account for organizational
structure at the patent application time
Knowledge breadt
h
(FIRM BREADTH
Entropy measure of knowledge diversification based on inventive IPCR patent classes.
Higher values indicate higher degree of knowledge diversity. I used the full range of
inventive IPCR patent classes, not just the main patent class.
Source: Firms’ patent stock (see above)
Age
(FIRM AGE)
Number of years since founding.
Source: Corporate Affiliations; Factiva; Companies’ web pages
Biotechnology firm
(BIOTECH)
Coded 1 if the firm’s main activity was in the biotechnology industry
Source: Corporate Affiliations; Factiva; Companies’ web pages
Principal Investigators (PI)
Lab Size
(LAB SIZE)
Number of people associated with Principal Investigator’s lab.
I obtained accurate information on the lab size for 40% of the sample. For the remaining
scientists, I estimated the lab size from corroborating various sources (e.g. faculty web
sites, local news articles), and in particular, from carefully identifying the investigator’s
co-authors at the same university during a three-year window prior to the contract date.
Although not perfectly measured, this variable captures the variation in the human capital
resources that principal investigators could mobilize for a project.
Source: Elsevier’s Scopus; ISI Web of Science; Scientists’ web pages; Lexis-Nexis
Publishing
Capabilities
(PI PUB CAP)
Cumulative number of publications weighted by the number of citations (as of April
2010). A 10% yearly depreciation rate has been applied.
Source: ISI Science Citation Index Expanded
Patenting
Capabilities
(PI PAT CAP)
Number of patents and patent applications in which the scientist appears as inventor
cumulated over a six-year window prior to collaboration and weighted by patent citations
(self-cites excluded) as of June 2010. A 10% yearly depreciation rate has been applied.
Source: Delphion
Knowledge breadt
(PI BREADTH)
Entropy measure of diversification based on MESH descriptor/qualifier keyword
combination.
Source: Medline and Medical Subject Headings thesaurus of the National Library of
Medicine
Academic age
(PI AGE)
Number of years since the highest degree was obtained.
Source: Professors’ CV; University Registrar
Academic title Dummy variables for each title category: Assistant; Associate; Professor; Chairman/Chief
Source: Professors’ CV; University Registrar
36
Table 2. Variable measurement and empirical predictions
Hypothesis Firm Side Scientist Side Theoretical
Prediction
Relationship between Variable Measurement
and Expected Sign
Expected
s
ign
H 1 Publishing
Capabilities
Publishing
Capabilities
Complementarity High values on both variables indicate superior
publishing capabilities. A positive sign is consistent
with a complementary relationship.
+
H2 Patenting
Capabilities
Publishing
Capabilities
Complementarity High values indicate superior patenting, respectively,
publishing capabilities. A positive sign is consistent
with a complementary relationship.
+
H3a Patenting
Capabilities
Patenting
Capabilities
Complementarity High values on both variables indicate superior
patenting capabilities. A positive sign implies
complementarity.
+
H3b Patenting
Capabilities
Patenting
Capabilities
Substitution High values on both variables indicate superior
patenting capabilities. Hence, a negative sign (where
high levels on one side of the market are associated
with lower levels on the other side of the market)
implies substitution in patenting capabilities.
-
H4a Knowledge
Breadth
Knowledge
Specialization
Complementarity On both sides, the entropy-based ‘Knowledge
diversification’ measure increases with the diversity of
knowledge, such that high values imply ‘breadth’ or
‘diverse knowledge’ and lower values indicate
‘specialization’ or ‘focused expertise’. Theoretically,
complementarity is expected between breadth (i.e. high
values of the “Knowledge diversification” index) on
the firm side and specialization (i.e. low values of the
‘Knowledge diversification’ index) on the scientist
side. Hence, when the direction of measurement of the
‘Knowledge diversification’ variables is taken into
account, a negative sign indicates complementarity.
-
H4b Knowledge
Specialization
Knowledge
Breadth
Complementarity From a theoretical perspective, complementarity is
expected between specialization (i.e. low values of the
‘Knowledge diversification’ index) on the firm side
and breadth (i.e. high values of the ‘Knowledge
diversification’ index) on the scientist side. Thus, a
negative sign is consistent with the predicted
complementarity relationship.
-
37
Table 3. Descriptive Statistics and Correlations
Mean Std. Dev. Min Max 1 2 3 4 5 6 7 8 9 10 11 12 13 14
1.Size 23110.73 34486.16 1 156400 1
2
.Publishing Capabilities 37835.48 57591.10 0 221509 0.71 1
3
.Patenting Capabilities 5041.54 8551.80 0 65582 0.26 0.30 1
4
.Knowledge breadth 4.41 2.09 0 7.19 0.64 0.61 0.43 1
5
.Age 47 46.84 1 155 0.52 0.31 0.16 0.64 1
6. Biotechnology firm 0.26 0.43 0 1 -0.54 -0.29 -0.31 -0.52 -0.4 1
7
.Lab Size 17.40 13 1 41 -0.10 -0.09 -0.09 -0.10 -0.11 0.00 1
8
.Publishing Capabilities 1219.06 1383.27 1 12671.43 -0.06 0.04 -0.01 0.09 0.02 -0.04 0.55 1
9
.Patenting Capabilities 41.97 293.22 0 4382.99 -0.04 -0.09 -0.07 -0.05 -0.01 0.05 -0.06 0.31 1
10.Knowledge breadth 4.75 0.52 2.20 5.79 -0.09 -0.06 -0.12 -0.09 -0.14 0.09 0.56 0.37 0.26 1
11.Academic age 17.12 7.35 3 53 -0.09 -0.13 -0.13 -0.09 -0.10 0.07 0.40 0.12 0.01 0.50 1
12.Associate Professor 0.29 0.45 0 1 0.07 0.06 0.12 0.08 0.07 -0.06 -0.08 -0.05 -0.10 0.04 -0.06 1
13.Full Professor 0.35 0.48 0 1 -0.13 -0.10 -0.13 -0.06 -0.06 0.05 0.44 0.43 0.13 0.44 0.39 -0.36 1
14.Chair/Chief 0.12 0.32 0 1 0.01 0.03 -0.02 0.04 -0.04 0.05 0.26 0.40 0.23 0.31 0.34 -0.23 -0.20 1
38
Table 4. Point Estimates and 95% Confidence Intervals
Z-Score Transformation Log Transformation
Relationship Model 1
Model 2
Model 3
Model 4
Model 5
Model 6 Model 7
Baseline FIRM SIZE *
LAB SIZE 1 -1 -1 1 1 1 1
H1 FIRM PUB CAP *
PI PUB CAP
9.22
(5.33; 11.97) … …
3.56
(2.97; 7.10)
6.78
(3.00; 9.95)
3.35
(1.25; 4.72)
4.03
(1.66; 5.77)
H2 FIRM PAT CAP*
PI PUB CAP
-1.01
(-3.18; 2.17) … …
-1.02
(-2.96; 3.21)
-0.87
(-3.03; 3.88)
-1.04
(-5.60; 1.02)
-1.26
(-6.49; 2.95)
H3 FIRM PAT CAP*
PI PAT CAP
-15.91
(-18.78; -10.36) … …
-7.23
(-11.35; -5.32)
-4.61
(-9.71;-2.18)
-2.83
(-5.42; -1.07)
-2.66
(-5.49; -1.43)
H4 FIRM BREADTH*
PI BREADTH
-4.78
(-6.65; -1.24) … …
-1.93
(-4.91; -0.84)
-2.89
(-5.12; -0.71)
-4.24
(-10.98; -3.46)
-13.67
(-16.88; -7.79)
5 FIRM SIZE*
PI PUB CAP
5.26
(3.21; 8.15) 9.72
(3.05; 12.30)
3.97
(1.64; 5.86)
6.61
(2.75; 9.36)
0.17
(-0.66; 3.24)
1.35
(0.92; 3.02)
6 FIRM SIZE*
PI PAT CAP
-21.54
(-23.85; -17.25) -12.85
(-18.81; -4.23)
-9.37
(-11.47; -5.11)
-3.21
(-6.95; -1.43)
-1.02
(-3.19; 0.99)
-0.45
(-4.29; 1.53)
7 FIRM SIZE*
PI BREADTH
-0.31
(-4.40; 1.15) -6.09
(-7.54; -2.18)
-0.35
(-3.28; 1.63)
-5.86
(-8.17; -2.27)
-19.74
(-24.40; -15.71)
-10.25
(-16.68; -7.83)
8 FIRM PUB CAP *
LAB SIZE
-3.66
(-6.45; -1.16) -1.25
(-6.45; -0.37)
-3.94
(-7.86; -1.43)
-7.48
(-10.60; -3.54)
-2.23
(-5.88; -1.05)
-2.64
(-6.76; -1.15)
9 FIRM PAT CAP *
LAB SIZE
-0.78
(-2.59; 4.06) 0.23
(-4.77; 2. 57)
-0.64
(-5.77; 2.41)
-0.32
(-3.15; 4.16)
1.46
(-4.48; 3.80)
1.01
(-3.65;5.16)
10 FIRM BREADTH*
LAB SIZE
-0.24
(-2.40; 5.73) 0.10
(-3.30; 4.81)
0.68
(-3.60; 5.94)
0.85
(-2. 55; 5.48)
8.92
(2.55; 9.28)
6.61
(1.73; 8.33)
11 FIRM AGE *
PI AGE
-0.93
(-3.92; -0.08)
0.04
(-5.90; 2.87)
-0.60
(-4.63; 2.39)
-0.63
(-3.90; 1.11)
-0.89
(-4.20; -0.12)
-2.86
(-5.90; -0.53)
-5.89
(-9.33; -2.98)
12 FIRM SIZE *
PI AGE
-1.11
(-4.07; -0.52)
-0.24
(-4.78; 3.49)
-1.36
(-3.10; -1.06)
-0.98
(-4.01; -0.50)
-0.60
(-3.27; 0.29)
-5.06
(-10.77; -2.78)
-3.06
(-6.50; -0.75)
13 FIRM AGE *
ASSOCIATE
1.77
(-0.84; 4.15)
0.56
(-1.64; 4.22)
1.98
(-4.39; 3.25)
3.97
(-0.53; 5.58)
3.46
(-0.49; 5.83)
2.54
(-0.93; 5.36)
2.60
(-3.30; 5.27)
14 FIRM AGE *
PROFESSOR
5.84
(1.13; 6.42)
0.30
(-0.84; 4.87)
0.63
(-4.64; 2.81)
1.72
(0.74; 4.63)
2.63
(1.40; 6.14)
11.51
(9.65; 17.56)
3.90
(1.34; 8.56)
15 FIRM AGE *
CHIEF
-4.87
(-7.58; -2.21)
-0.65
(-6.70; 0.26)
-1.84
(-6.90; -1.39)
-4.15
(-8.42; -2.22)
-6.33
(-8.90; -3.93)
-9.00
(-16.26; -4.64)
-8.00
(-13.59; -5.23)
39
16 FIRM SIZE *
ASSOCIATE
-0.02
(-2.67; 3.50)
0.35
(-5.88; 3.11)
0.69
(-3.87; 3.83)
1.86
(-4.24; 3.13)
0.82
(-3.48; 2.40)
4.24
(-2.37; 6.41)
-0.47
(-4.81; 5.31)
17 FIRM SIZE *
PROFESSOR
-17.01
(-19.77; -11.34)
-2.12
(-6.96; -1.50)
-8.64
(-13.52; -4.96)
-3.73
(-7.13; -1.76)
-8.85
(-10.48, -3.55)
-5.45
(-8.89; -2.57)
-4.11
(-9.82; -2.63)
18 FIRM SIZE*
CHIEF
5.78
(3.30; 8.12)
2.01
(1.89; 7.28)
3.26
(0.92; 5.32)
7.53
(4.34; 9.85)
6.41
(2.80; 8.33)
4.92
(1.76; 7.08)
3.13
(1.17; 6.55)
19 FIRM AGE*
PI PUB CAP
0.60
(-2.30; 3.19) ……… 0.81
(-4.30; 3.23) ………
20 FIRM AGE*
PI PAT CAP
-0.42
(-4.20; 3.62) ……… -2.56
(-5.06; 2.47) ………
21 FIRM AGE*
PI BREADTH
-3.52
(-8.30, -1.92) ……… -23.72
(-27.31; -16.63) ………
22 BIOTECH*
PI PUB CAP
-1.76
(-4.26; 2.85) -6.36
(-8.19; 3.09)
23 BIOTECH *
PI PAT CAP
2.33
(1.26; 6.79) 11.99
(5.52; 14.13)
24 BIOTECH *
PI BREADTH
2.52
(1.49; 5.25) 8.80
(6.45; 12.30)
% Inequalities
predicted 74% 59% 61% 75% 76.5% 73.5% 74%
Note: Parameters in bold are significantly different than zero.
To estimate the model, I adapted Santiago and Fox (2008)’s template in Mathematica software for the particular production functions that are
tested here. For optimization, I used the standard differential evolution procedure in Mathematica 7.0.
40
Appendix
I illustrate how the method works by taking two random matches from the sample and
estimating a model based only on the main four hypotheses. Below, I denote the two matches
as Match 1= {Firm 1, Scientist 1} and Match 2= {Firm 2, Scientist 2}.
MATCH 1 MATCH 2
ATTRIBUTES Firm 1 Scientist 1 Firm 2 Scientist 2
Size
(Firm, respectively, Lab)
21000 18 140 4
PubCap
Publishing Capabilities
29000 2700 700 1200
PatCap
Patenting Capabilities
2500 0 200 10
KDiv
Knowledge Diversity
5 4 2.5 3
The match output (i.e. alliance production function) takes the following functional
form:
g (F,S |β)= β0 FirmSize * LabSize + β1 PubCapf * PubCaps + β2 PatCapf *
PubCaps + β3 PatCapf * PatCaps + β4 KDivf * Kdivs
Note that we don’t have information on the left hand side of the equation (we don’t
know how much innovation/knowledge output each alliance generates). On the right hand
side, the only relevant relationships for estimating complementarity and substitution are the
interaction terms between the capabilities of the partners.
To generate the point estimates, the method compares the output generated by any
two observed matches - as above, {Firm 1, Scientist 1} and {Firm 2, Scientist 2} - with the
counterfactual matches obtained by exchanging the alliance partners: {Firm 1, Scientist 2}
and {Firm 2, Scientist 1}.
The match production functions of the observed matches are:
{Firm 1, Scientist 1} generate together:
(β0 21000*18 + β1 29000 *2700 +β2 2500 *2700 + β3 2500 *0 + β4 5 *4) (1)
41
{Firm 2, Scientist 2} generate together:
(β0 140* 4+ β1 700 *1200+ β2 200 *1200 + β3 200 * 10 + β4 2.5 *3 ) (2)
The match production functions of the counterfactual matches are:
{Firm 1, Scientist 2} generate together:
(β0 21000 * 4 + β1 29000*1200 + β2 2500 * 1200+ β3 2500*10 + β4 5 *3) (3)
{Firm 2, Scientist 1} generate together:
(β0 140 *18+ β1700*2700+ β2 200 * 2700+ β3 200*0 + β4 2.5*4 ) (4)
The inequality that lies at the core of the estimation procedure is the following:
(1) + (2) > (3) + (4)
This relationship translates into:
(378000 β0 + 78300000 β1 +6750000 β2 + 20 β4) + (560 β0 + 840000 β1 + 240000 β2 + 7.5
β4) > (84000 β0 +34800000 β1 + 3000000 β2 + 25000 β3 + 15 β4) + (2520 β0 + 1890000 β1 +
540000 β2 + 10 β4)
Equivalently: (292040 β0 + 42450000 β1+ 3450000 β2 - 25000 β3 + 2.5 β4) > 0
Similar inequalities are written for all other observed pairs in a market and the
corresponding counterfactuals. As explained in the paper, each year constitutes a market in
this empirical context (up to a total of ten markets from 1995 to 2004). Note that partner
exchanges occur only among pairs belonging to the same market-year.
The method estimates both the sign and the magnitude of the coefficients β1 to β4 but
only the sign of β0. The coefficient β0 represents the ‘scale’ of the match production output.
The estimated values of β coefficients are those that maximize the number of
inequalities satisfied. The significance of the coefficients is given by the 95% confidence
intervals obtained from generating a large number of subsamples of matches.
... Matching theory postulates that healthy relationships equally consider all members' preferences, opportunities, and constraints by using information "on the characteristics or resources that each side values in the other" (Logan, 1996: 117). Matching theory has been widely applied to study different types of social matches, such as employer-employee matching (Fujiwara-Greve & Greve, 2000), alliance formation (Mitsuhashi & Greve, 2009), between entrepreneurs and potentially valuable contacts (Vissa, 2011), and between firms and research scientists (Mindruta, 2013). When firms from developing economies enter the markets of developed countries, they not only face extremely complex environmental pressures (Schilke, 2018;Wei & Clegg, 2015), but are also subject to disadvantages in terms of internationalization experience, technology accumulation, and knowledge reservation (Deng, 2009;Thomas et al., 2007). ...
... In this case, an organization can easily coordinate the relationships with each other and develop consistent tactics to achieve common goals (Thornton et al., 2012). This is in line with the notion of compatibility in matching theory, where compatibility helps to improve the quality of the match through similarities in management, operations, culture, and goals of both parties (Mindruta, 2013;Mitsuhashi & Greve, 2009;Vissa, 2011). Cross-border mergers and acquisitions can be viewed as corporate decisions in a complex environment where each firm's actions are favored by groups governed by some institutional logics (Henrich et al., 2017). ...
... Finally, we have made some contributions to the matching theory. Previous studies have already tried to use matching theory to explain employer-employee matching (Fujiwara Greve & Greve, 2000), alliance formation (Mitsuhashi & Greve, 2009), entrepreneurs and potentially valuable contacts (Vissa, 2011), and firms and research scientists (Mindruta, 2013), problem searching and solving (Haas et al., 2015). A major difference between this and our study is that while previous studies assumed matching processes that occur in the external environment (outside organizational boundaries), we apply matching theory to the internal organization, examining the matching of different institutional logics. ...
Article
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When cross-border acquisitions take place, whose institutional logics should dominate the control in the daily operation of the acquired entity — the acquirer or the acquiree? To answer this question, this paper investigates how Geely, a Chinese automaker, successfully acquired Volvo from Sweden, a developed country, and managed the differences in the institutional logics of the two firms by transforming its dominant institutional logic. Through the lens of matching theory, we employ an inductive approach and conduct a longitudinal case study of Geely’s acquisition. We find that matching commercial and social logic is an inevitable requirement to cope with external institutional pressures in cross-border acquisitions. We further reveal that the structured interaction between compatibility and complementarity facilitates the matching process between commercial logic and social logic, resulting in a synergistic logic via the three different mechanisms of compatibility, complementarity, and co-evolution. Our findings challenge previous research that focuses on conflicts as the foremost drivers of the transformation of different institutional logics in organizations. Based on our findings, we develop a matching process model that offers insights for firms from developing economies to navigate dominant institutional logic transformation and thrive in the marketplace through their strategic cross-border acquisitions.
... In other words, many prior studies have skipped an intermediate-level outcome (impactful versus non-impactful innovations) in terms of innovation performance and jumped to financial performance. Furthermore, even the few studies that have examined the effects of market-based alliances and science-based alliances on innovation performance have not explored the boundary conditions for those relationships-specifically the role of the top management, which plays a key role in strengthening, or weakening, the effects of science-based vs. market-based alliances on innovation (Gretsch et al., 2019;Lee, 1996;Mindruta, 2013). We address the aforementioned gaps. ...
... We controlled for several alternative explanations for the variation in the dependent variable. First, we included firm age, measured as the number of years from the firm's original establishment (George et al., 2002;Mindruta, 2013). Second, prior studies have suggested that firm size matters with respect to both the types of relationships that firms have with universities as well as their strategic implications (Ettlie et al., 1984;Rothaermel & Thursby, 2005;Santoro & Chakrabarti, 2002). ...
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Drawing on the open innovation literature, we examine the relationship between alliances with science-based and market-based partners on the one hand, and impactful and lower-impact innovations, on the other hand. Specifically, we predict that alliances with science-based partners will boost impactful innovations while alliances with market-based partners will boost low-impact innovations. We also examine how the social capital of the Board of Directors moderates these relationships. We base our analyses on a large dataset of Chinese firms constructed from diverse sources and find strong support for our hypothesized relationships. We identify the theoretical and managerial implications of our study.
... Studies have pointed to characteristics of the institutional environment in explaining the difficulties academic founders face to start and grow their venture (Klingbeil et al., 2018). Researchers have pointed out that institutional characteristics at the national level (e.g., intellectual property rights legislation) and at the level of the university (e.g., whether entrepreneurial activities are being rewarded, and how technology-transfer and industry collaboration are being organized) can hinder the creation and economic performance of academic start-ups (Fini et al., 2017;Huyghe and Knockaert, 2015;Lacetera, 2009;Mindruta, 2013;Ziedonis, 2007). They have also advocated that the economic success of academic ventures can only be improved if institutional changes at the university level are consistent with the broader institutional environment to which start-ups are exposed (Eesley et al., 2016). ...
... Many ventures keep hovering around breakeven for extended periods of time, being labelled as technology zombies by some observers (Pisano, 2006). Researchers have identified institutional factors at the level of nations, regions, and universities that hinder academic founders in starting and growing their venture (Eesley et al., 2016;Fini et al., 2017;Huyghe and Knockaert, 2015;Klingbeil et al., 2018;Lacetera, 2009;Mindruta, 2013;Ziedonis, 2007). However, the decision to start and grow an academic spin-off is an individual decision (Balven et al., 2008). ...
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... [15], [3], [28], [30], [31] ID Critical Success factors Description References CF.08 Effective Change Management Ability to handle unexpected changes or deviations in the original project plan; flexibility promoting the creativity of stakeholders. ...
... [6], [24], [25], [27], [30] ID Critical Success factors Description References ...
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University-industry R&D collaborations (UICs) play a vital role in stimulating open innovation that leads to new products, processes, and services that creates value for customers and broader societal impact. UICs, however, commonly fail to meet these stakeholders' benefits. This study identifies thirty-four critical success factors (CSFs) for improving UIC success. The study includes a systematic literature review and a longitudinal UIC case study between Bosch Car Multimedia in Portugal and University of Minho, a multi-million Euro R&D collaboration from 2013 to 2021. The importance of the CSFs is discussed in the context of the UIC lifecycle. A survey among researchers and industry practitioners involved in R&D collaborative projects was completed to confirm the analysis of the empirical results. This paper provides UIC managers with CSFs, which, when addressed competently, can provide a basis for successful UIC projects and sustainable university-industry collaborations.
... However, their small size constrains their ability to develop internal resources and capabilities, posing challenges to their innovation efforts (Vanacker et al., 2014). To compensate, SISMEs often turn to universities as major sources of advanced knowledge (Mindruta, 2013) and initiate formal and/or informal U-F interactions to acquire scientific knowledge and technological resources (Díez-Vial and Montoro-Sánchez, 2016;Schaeffer et al., 2020). U-F formal interactions are established through contractual agreements, including R&D alliances and patent licensing (Azagra-Caro et al., 2017;Landry et al., 2010), whereas U-F informal interactions are comprised of non-contractual linkages, such as individual contacts between firm employees and university staff, and participation in academic events (e.g., seminars, conferences, workshops, etc.) (Azagra-Caro et al., 2017;Dahl and Pedersen, 2004;Diánez-González and Camelo-Ordaz, 2019). ...
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This study examines how university-firm (U-F) interactions affect innovation speed in science-intensive small and medium-sized firms (SISMEs). We distinguish between formal and informal U-F interactions and build on dynamic capability theory to argue that (1) U-F R&D alliances enhance innovation speed through firm-level entrepreneurial orientation (EO), and (2) frequent U-F informal contacts weaken the effects of U-F R&D alliances on innovation speed. Analyzing a sample of 268 SISMEs from 10 science parks in China, the results of the partial least squares structural equation modeling (PLS-SEM) support our hypotheses. Furthermore, fuzzy-set qualitative comparative analysis (fsQCA) identifies various configurations of U-F R&D alliances, U-F informal contacts and EO, along with other organizational, science park and environmental conditions, that lead to higher or lower innovation speed in SISMEs. Our findings offer valuable theoretical and practical insights, advancing our understanding of the complex relationship between U-F interactions and innovation speed in SISMEs.
... Gulbrandsen and Thune (2017) have posited that non-academic experience was positively related to academic engagement and asserted there was no effect on academic productivity of the collaborating faculty members. Mindruta (2013) found the publishing capabilities of the firms and university scientist were complementary for innovation but substitute patents. According to study, more specialized individual firms create more value by teaming up with more knowledge diversified partners. ...
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The collaborative relationship between university and industry is becoming crucial research phenomena for professors, students, industrial leaders, government and the general public in the advanced developing as well as underdeveloped economies. It has become more imperative to the management schools and institutes and research centers. In the prevailing knowledge economy universities are called to produce innovative and creative manpower ready to job in the organizations. This research was conducted in Nepalese business management schools operating under the three leading universities, namely Tribhuvan University, Pokhara University and Kathmandu University. Apart from the students and professors, the perception of business community leaders also has been included in regard to attainability of the objectives of university industry collaboration in Nepal. The objective of the study was to find the perception of students, course facilitators and industrial leaders about the level of attainability of the stated objective of UIC. With some differences all respondentsfound the objectives of UIC are attainable in Nepal. Such kind of research is important to the universities, especially business management educators, the industries and the government to frame education policy and curriculum.
... Future research should study the effects of startup visions and applicant characteristics using data that allow two-sided matching models (for guidelines and examples, see Honoré and Ganco 2020, Mindruta 2013, Mindruta et al. 2016. ...
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For-profit social ventures are proliferating. They often communicate social visions, presenting an ideal future where the ventures resolve environmental or societal issues. We study whether social vision communication helps a startup to recruit talent—a fundamental problem for growth. We argue that jobseekers are less likely to apply to ventures communicating a social vision as they perceive reduced career advancement opportunities. We conducted two complementary studies to test our theory. Study 1 enlisted data from a job board for startups to show that ventures communicating a social vision receive 46.3% fewer job applications. Study 2 replicated this finding in a field experiment that further reveals the underlying mechanism: social vision communication limits jobseekers’ perceived career advancement opportunities. Both studies show that higher remuneration can compensate the negative effect of social vision communication. Our findings advance research on purpose-driven organizations, human resources, entrepreneurship, and vision communication to caution entrepreneurs against social vision communication as a recruitment strategy. Supplemental Material: The online appendix is available at https://doi.org/10.1287/orsc.2023.1671 .
... Tidd et al. introduced the matching theory in the field of economics into the field of management and proposed that the process of enterprise innovation was not only the process of managing the knowledge of enterprises, but also the process of continuously matching and integrating external knowledge and improving and expanding their own knowledge stock of enterprises [17]. Mindruta further explored the knowledge matching mechanism behind the formation of enterprise research cooperation from the perspective of knowledge resources according to the different knowledge attributes of knowledge supply and demand [18]. Yan and Bian start the research from knowledge complementarity, revealed how knowledge matching could meet the needs of both supply and demand of knowledge resources and transform knowledge resources into effective resources of enterprises, and divided knowledge matching into different levels of source knowledge, knowledge carrier, and application environment [19]. ...
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Taking unicorn enterprises as the research objects, this study constructs the conceptual model of function mechanism of intellectual property capability on relay innovation performance and introduces knowledge matching as the mediating variable and relationship learning as the moderating variable. Hybrid methods composed of fusion of rough set and binary firefly algorithm based on community weak connection mechanism (CWLBGSO), directed acyclic graph (DAG), and Bootstrap structural equation modeling (Bootstrap SEM) are used to carry out empirical analysis of the conceptual model of function mechanism. The empirical analysis results show that strong intellectual property capability has a positive role in promoting the relay innovation performance of unicorn enterprises, knowledge matching plays the positive mediating role between intellectual property capability and relay innovation, relationship learning plays the moderating role of the relationships between intellectual property capability and relay innovation, relationship learning plays the moderating role of the relationships between intellectual property capability and knowledge matching, and relationship learning plays the moderating role of the relationships between knowledge matching and relay innovation.
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This paper experimentally examines the determinants of the deviation between potential and realized value creation in strategic alliances. To better understand how decision making in alliances may influence success, we use an experimental design that juxtaposes two important factors that affect alliance members' decisions: economic incentives and communication. The evidence from our experiment sheds light on the relative impact of each, and more importantly, how both factors interact to explain successful outcomes.
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