The True Cause of Coronary Artery Disease; Cholesterol is Irrelevant

Abstract

This report is a synthesis of 22 studies which concludes that coronary artery disease is caused by free radical damage to tumor suppressor genes, which mutation allows cells to proliferate out of control to create benign mini tumors between the endothelium lining and the smooth muscle walls of arteries. As these tumors grow, they cause tiny tears in the endothelium that are patched with interlacing filaments of fibrin. This rough scar tissue traps minerals (especially calcium), heavy metals, macrophages, and cellular debris. The final smooth layer of cholesterol that is applied over this arterial plaque plays no causal part in its development. Recent studies indicate that nearly 75 percent of patients hospitalized for a heart attack had cholesterol levels which indicate they were not at high risk for a cardiovascular event, according to current national cholesterol guidelines. Thus, there is no causal relation between serum cholesterol levels and coronary artery disease.

Full text

The True Cause of Coronary Artery Disease;
Cholesterol is Irrelevant
David Rowland




   
              
  
  ! "
#                  
#$# 
%&   '   ( #  
       (   # #      
       #

Keywords: coronary artery disease, cardiology, atherosclerosis, arteriosclerosis, free radicals,
cholesterol

Introduction
) ##   
 
 * +,,- 
37,38
. /01 
     1 2  
( #$((
 
%&'(
 #            (    # #
2 (
#

  #
#3
Cholesterol is a Vital Bodily Substance
   3                       
                         (   
!"# (
 3
                &   
  #
#44(
#
 #51
      1                  5
*             +11        

The Cholesterol Myth
+,15+,+-6,7
2##' $ '
 #+11 
  ##             
#  '3
 (    #         6
## 
   8
  +,&-    7                  
 3 9
7 # 
 3               3 
)      .
7                  #      #   
 

 89 '8
  10
)(  !,:";
<  !9+:#&5:";
< ( !5:#-+:"
Free Radical Hazards
  11  
  (##
     
 #12
   <                 
)3
12,22
=3  #  (
#!>8 "'( 
12#
##13,14,15 ? #
                    @  A    
 3' '
(#+,11
      / 
       #     (     +1     
( 14
.        
  +,&&  
#342+,91(
 36
  +,9+                      
35B ( 8+,9136

The Structure of Arterial Plaque

A #.#$
###
#
)(  16,19-21,23-25 #
 (  (
 #33@
                              
  
  
     #     ##
 ( A #
    (    #$ #
26
)  # 
17,27 @ 
  3
$$
 28 
@#AA
     # #   
 (

) 
  18 )  
 # 
 (# 
     
8(  3
 ! "#  29-31 
 
  #                   
 3   ##      <
$

                3'        (32
##C!+" #
  ;!"# 
 
Conclusion
                   
                           
      
        
  !  "#   
   #$
# 0 3#;#

Declarations
=#D<
D<
 D 
)D<
6D# 
( D<
References
+ E=E0 1CAmerican
Journal of Medicine1+F;!+%"C51%85+
 )G0#B(6#
(American Heart Journal?E+11,/#
4
- HI2 
F @2B02  8
##AFAmerican
Journal of Geriatric Psychiatry115;+9!,"C%5+8%5&
& HBIHarvard Special Health Report.#B0
9 (  JS Peterb Izviest Imp
Voyenno-Med Akad.J+,15;+9C+&FD+%-
% (<0/3 8
'Zentrbl Allg Pathol Anat+,+-;FC+D,

5 #(#/The Cholesterol Myths@111C<?+-%8
+-5
, 7C Journal of Mount Sinai Hospital
+,&-;1C++58+-,
+1 #(#/8;$
 British Medical Journal+,,;!-1&"C+&8+,
++ H@I4#0 
+ ?E2? 4)C
 #Indian Journal of Clinical Biochemistry1+&E;-1!+"C++89
+- 0K42 #
 British Medical Journal1+,;-9FC(&F1
+F <EE67E. 89##C
3'Open Heart1+5;&
+& K$4H IB-11+-4#0 
+9 @B7G#7=Medical Principles
and Practice11-;!+"C+8,
+% HBITaber’s Cyclopedic Medical Dictionary (ed 23)1+%)# 
+FF8+FF-
+5 H)ITaber’s Cyclopedic Medical Dictionary (ed 23)1+%)# ,-
+, B30D 3
 Basic Research Cardiology111;,&!0+"C+9&8+%+
1 7)2)#Proc Royal College Physicians
Edinburgh+,,5;5C+18++1
+ 20B)3#
Internet Journal of Medical Updates 119E8*+<
 2(7B*Clinics in Laboratory
Medicine+,,-E;+-!"CF9-8F51
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11&;&C,8-5
F 0#0G C
88Diabetes Metab Res Rev1+&);-+!"C++-8+9
& <(=L43
# =#Journal of Clinical Biochemistry and Nutrition1++E;F5!+"C-8%
9 H?I2/#B
% H) I@(
5 (E<0E22?$Arteriosclerosis, Thrombosis, and
Vascular Biology1+,;-,!+1"
, #BE 8$New England Journal of Medicine
+,,%;-9C+-+8+-+F
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 C#Journal of the American College of Cardiology
1+F;9-!+9"C+91F8+9+9
-+ 7KG. # # #
International Journal of Medical Science1++;5!9"CF&98F91

- # B3' 
3Eur J Clin Chem Clin Biochem+,,9;-F!5"C&,,8
915
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#  Food and Nutrition Sciences
1+&;1%!15"C95,8%1
-& 24.E  8- 89
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-9 E0GEC
 American Journal of Public Health1+-E;+1-!%"C+1%8++5
-% ?(MB#0?3#
International Journal for Vitamin and Nutrition Research
11E%
-5 <#(0B0B48  (
 3#C 
Archives of physiology and biochemistry11+,C+85