Daniëlle Otten

Universitätsmedizin der Johannes Gutenberg-Universität Mainz · Department of Psychosomatic Medicine and Psychotherapy

Background: Preterm birth is a risk factor for a variety of detrimental health outcomes. Previous studies have identified recalled (or remembered) parental rearing behaviour as a potential modifier of preterm individuals’ mental health in adulthood. However, no investigations to date have contrasted the parents’ and children’s views, explored wheth...

Background Depression is associated with an increased risk for type 2 diabetes mellitus. However, depression may take different courses, and it is not fully understood how these affect the development of diabetes. It is further to be determined whether sex modifies the association between depression and type 2 diabetes. Methods We analyzed data fr...

Previous studies on self-rated health and mortality have usually not differentiated between physical and mental health, respectively have not considered physical diseases. This study aims to determine self-rated physical and mental health from middle to old age, examine associations with mortality adjusted for objective risk factors and assess effe...

Introduction Stigma is an individual and societal process based on attitudes and power and relates to both spatial disparities and social distinction. In this study, we examined differences in desire for social distance toward people with mental illness within a city using social and spatial information. Methods ANOVAs and Scheffé post-hoc tests a...

Background Mental resources such as optimism and social support are important to face different stressors. The aim of this study is to identify groups in the population that are similar in terms of their mental resources. Methods For this purpose, a randomly selected general population community sample was used, representative for the city of Leip...

Loneliness is an established risk factor for impaired health. However, the evidence of whether increased alcohol consumption is a coping mechanism to alleviate loneliness for both genders remains sparse. The cross-sectional study included 8898 men and 8910 women (mean age of 56.2 ± 11.5 years) from three population-based cohort studies in Germany (...

Associations of preterm birth with later-life mental distress are well-established. A research gap concerns the role of psychosocial factors such as the family context. This study investigated associations of recalled parental rearing behavior with both preterm birth characteristics and psychological symptom burden later in life. Based on birth re...

Purpose Mental distress has become a major public health concern. Temporal trends in psychological distress are complex and depend on numerous factors. In this study, we examined age-period-cohort effects for mental distress including gender and German region over a 15 years’ time span. Methods Data on mental distress from ten cross-sectional surv...

Background: The present study aimed to investigate how depressive symptoms affect bodyweight change (gain and loss), and how this association is intertwined with other psychosocial and biomedical factors in the adult general population. Methods: In a population-based, prospective, observational single-center cohort study in the Rhine-Main-Region...

Aim: The present study investigated regional differences in response behaviour for the Patient Health Quetionnaire-9. We tested for measurement invariance and differential item and test functioning between formerly divided East- and West-Germany: the former German Democratic Republic and Federal Republic of Germany. Diverging socialization experie...

Zusammenfassung Ziel der Studie Das Ziel dieser Studie ist es, zu untersuchen, inwiefern innerdeutsche Migration (Binnenmigration) mit allgemeiner psychischer Belastung, Somatisierung, Depressivität und Angst assoziiert ist. Methode Daten aus zwei bevölkerungsrepräsentativen Befragungen (2020 und 2021; N=4922) wurden genutzt, um mit Hilfe von linea...

Zusammenfassung Erste Ergebnisse einer bundesweiten Studie deuten auf geschlechtsspezifische Muster mit weniger berichteten Fällen von Kindesvernachlässigung und Gewalt in den Neuen im Vergleich zu den Alten Bundesländern. Ziel der vorliegenden Studie war es diese Ergebnisse in zwei größeren regionalen Stichproben zu überprüfen. Methode: Prävalenze...

Chronic exhaustion is a consequence of detrimental working conditions and demands, as well as inadequate coping techniques, potentially resulting in burnout. Previous research has studied occupational environment and individual factors as predictors of exhaustion. Although these differ between former East and West German states, the regional distin...

Background: Depression, the most frequent and harmful mental disorder, has been associated with specific somatic diseases as the leading cause of death. The purposes of this prospective study were to predict incident chronic diseases based on baseline depressive symptoms and to test sex-dependent effects. Methods: In a representative German comm...

Background Suicidal ideation and behavior constitute important public mental health issues. In this study, we examined whether social integration prevents suicidal ideation over time and whether gender modifies this association. Methods Data from the Gutenberg Health Study (population-based representative community sample in midwest Germany) and t...

Objectives: Mental health differences between men and women can be attributed to sex or gender. Due to absence of brief assessments, contributions of gender expressions to the mental health gap between men and women have been understudied. The purpose of this study is to develop and validate a short screening measure of gender expression and test i...

Background : The association of depression with mortality and the significance of explanatory factors, in particularly gender, have remained an issue of debate. We therefore aimed to estimate the effect of depression on all-cause mortality, to examine potential explanatory factors and to assess effect modification by gender. Methods : We used Cox...

Zusammenfassung Fragestellung Welche Faktoren spielen für die psychische Gesundheit von Binnenmigrierten im Vergleich zu Nichtmigrierten eine Rolle?Methode Daten der Sächsischen Längsschnittstudie aus den Jahren 2010 und 2020 wurden benutzt, um mithilfe von Bootstrapping-basierten Mediationsanalysen Binnenmigrierte mit Nichtmigrierten in ihrem Grad...

Background: Sex and gender are important modifiers of mental health and behavior in normal times and during crises. We investigated whether they were addressed by empirical, international research that explored the mental health and health behavior ramifications after the onset of the COVID-19 pandemic. Methods: We systematically searched the datab...

Childhood maltreatment has been shown to relate to adult obesity. In this epidemiological study, we investigate the association between childhood maltreatment and waist-to-height-ratio (WHtR) in a sample of the German adult population, comprising of N = 2936 participants. WHtR, an indicator for risk of obesity, was the primary outcome. Childhood ma...

Background The Patient Health Questionnaire-9 (PHQ-9) has been proposed as a reliable and valid screening instrument for depressive symptoms with one latent factor. However, studies explicitly testing alternative model structures found support for a two-dimensional structure reflecting a somatic and a cognitive-affective dimension. We investigated...

In Germany, large, population-based cohort studies have been implemented in order to identify risk and protective factors for maintaining health across the life span. The purpose of this systematic review is to analyse findings from three large ongoing cohorts and to identify sex-specific prevalence rates, risk and protective factors for mental hea...

Depression has been associated with increased inflammation. However, only few large-scale, prospective studies have evaluated whether inflammation leads to new cases of depression and whether this association can be found in men and women. Longitudinal data of N = 10,357 adult participants with no evidence of depression at baseline (based on Patien...

Background Sex and gender are important modifiers of mental health and behavior in normal times and during crises. We investigated whether they were addressed by empirical, international research which explored the mental health and health behavior ramifications after the onset of the COVID-19 pandemic.Methods We systematically searched the databas...

Psychosomatic medicine in the Gutenberg Health Study (GHS) - research questions, measurement instruments, selected resultsGoal: Main questions from the Gutenberg Health Study (GHS) related to psychosomatic medicine are presented: (1) Prevalence and incidence of mental illnesses, (2) Sex-specific risk- and protective factors for mental health, (3) I...

Introduction Mental health is marked by gender differences. We formed a multi-cohort consortium to perform GEnder-Sensitive Analyses of mental health trajectories and study their implications for prevention (GESA). GESA aims at (1) identifying gender differences regarding symptoms and trajectories of mental health over the lifespan; (2) determining...