Christoph Wagner

Martin Luther University Halle-Wittenberg | MLU · Institute of Chemistry

Recently, glycogen synthase kinase-3β (GSK-3β) has been considered as a critical factor implicated in Alzheimer’s disease (AD). In a previous work, a 3D pharmacophore model for GSK-3β inhibitors was created and the results suggested that derivative ZINC67773573, VIII, may provide a promising lead for developing novel GSK-3β inhibitors for the AD’s...

Treatment of 3-formyl­acetyl­acetone with the amines benzyl­amine, tert-butyl­amine and (S)-methyl­benzyl­amine led to the formation of the corresponding Schiff bases 3-[(benzyl­amino)­methyl­idene]pentane-2,4-dione, C13H15NO2 (1), 3-[(tert-butyl­amino)­methyl­idene]pentan-2,4-dione, C10H17NO2 (2) and 3-{[(S)-benz­yl(meth­yl)amino]­methyl­idene}pen...

A series of Pd(II) complexes containing ortho-cyano-aminothiophenolate (ocap) ligands have been prepared and their molecular structures elucidated. Hg(II) ocap complexes, [Hg{SC6H3XN(CN)}]n (X = H, Me) (1), react with Na2S to afford HgS and Na2[ocap] which reacts in situ with K2[PdCl4] to afford palladium ocap complexes [Pd{SC6H3XN(CN)}]n (2). A...

Three thioether functionalized formamidines RNHC(H)NR (R=2‐SMe‐C6H4, 2‐StBu‐C6H4, 2‐SPh‐C6H4) were prepared from the corresponding amines RNH2 and triethyl orthoformate. X‐ray crystal structure determinations revealed the typical E configuration about the amidine C=N bond for all three compounds. The 2‐SMe and 2‐StBu derivatives exhibit the most fr...

Addition of 2-aminobenzothiazole (abt) and substituted derivatives to Hg(OAc)2 leads to the high yield formation of ortho-cyano-aminothiophenolate (ocap) complexes [Hg{SC6H3XN(C≡N)}]n (X = H, Me, Cl, Br, NO2) resulting from dehydrogenation...

Two thione and thionate based complexes were synthesized by simply reacting the ligand 2-mercapto-5-methyl-1,3,4-thiadiazole (HmtzS) with palladium(II) salt in a neutral or basic medium in 2:1 molar ratio. Reacting of resulting complex [Pd(mtzS)2] (2) with Ph2P(CH2)nPPh2 (n = 1-4), dppf, Ph3P or Ph3PS yielded mononuclear complexes, [Pd(mtzS)2(Ph2P(...

The Front Cover shows a synthetic step and example molecule of one of the most toxic compounds against the single most lethal bacterial pathogen, Mycobacterium tuberculosis, depicted microscopically in human macrophages and macroscopically on a culture plate. The beauty of the bacterial colonies is deceptive as it causes the White Plague aka Consum...

The reaction of [Hg(mbm)2] (mbm = o-SC6H4CONH2) with Na2S releases Na[mbm] which reacts with Pd(II) salts to give [Pd(mbm)2]. While its precise molecular structure is unknown, [Pd(mbm)2] reacts with two equivalents of PPh3 to afford trans-[Pd(κ¹-mbm)2(PPh3)2] in which the mbm ligands bind through a sulfur atom. With dppf, a similar complex, [Pd(κ¹-...

Treatment of 3-formylacetylacetone with the isomeric o -, m - and p -aminobenzoic acids led to the formation of the corresponding Schiff bases, namely, 3-[(2-carboxyphenylamino)methylidene]pentane-2,4-dione, 1 , 3-[(3-carboxyphenylamino)methylidene]pentane-2,4-dione, 2 , and 3-[(4-carboxyphenylamino)methylidene]pentane-2,4-dione, 3 , all C 13 H 13...

8‐Nitrobenzothiazinones (BTZs) are a promising class of antimycobacterial agents currently under investigation in clinical trials. Starting from thiourea derivatives, a new synthetic pathway to BTZs was established. It allows the formation of the thiazinone ring system in one synthetic step and is applicable for preparation of a wide variety of BTZ...

Reaction of mercury(II) acetate [Hg(Ac)2] or mercury(II) chloride [HgCl2] with two moles equivalent of Na[bit] (bit = benzisothiozolinate) afforded [Hg(bit)2] as white solid in 96 and 70% yield respectively. Treatment of [Hg(bit)2] with the bidentate ligands; 2,2-bipyridine (bipy), 1, 10-phenanthroline (phen) or ethylene diamine (en) in absolute et...

The addition of sodium hydroxide to a mixture of phenyl mercury acetate and 2-aminobenzothiazole in warm ethanol led to the high yield (84%) formation of [Ph-Hg(LH)]n (1), LH = the 2-cyanoaminothiaphenolate anion (SC6H4NHCN)⁻, resulting from monodeprotonation of 2-aminobenzothiazole and facile carbon–sulfur bond breakage. Reaction of 1 with Ph3P or...

C 24 H 60 Mo 2 N 6 , trigonal, R 3 ‾ $R\bar{3}$ (no. 148), a = 16.7680(8) Å, c = 9.7523(4) Å, V = 2374.7(2) Å ³ , Z = 3, R gt ( F ) = 0.0205, wR ref ( F ² ) = 0.0517, T = 213 K.

A lethal combination Although many human activities have clear negative effects on the natural world, there are also unforeseen consequences. Bald eagle mass death events in the southeastern United States may be one such downstream effect of human activity. After considerable effort, Breinlinger et al. identified the cause of these events as an ins...

The complex [Pb(tsac)2H2O] has been used as a synthon for the synthesis of a series of lead(II) thiosaccharinate mixed ligand complexes with the tertiary phosphines; PPh3, Ph2P(CH2)nPPh2, n = 1, dppm; n = 2, dppe; n = 3, dppp or the heterocyclic; 2-aminobenzothiophene (abtH), 2-acetamidopyrimidine (aampH) and 2-benzimidazolethiol (bimsH). The prepa...

Treatment of o ‐(diphenylphosphino)aniline with 3‑formylacetylacetone led to the formation of the ketimine type Schiff base 3‐(( o ‐diphenylphosphino‐phenylamino)‐methylene)‐pentane‐2,4‐dione ( o ‑PPh 2 ‐C 6 H 4 ‐NH‐CH=C(COCH 3 ) 2 , HL). Complexes [ML 2 ] (M = Fe, Co, Ni, Cu) were obtained from the reaction of HL with the corresponding metal aceta...

Eight palladium(II) pyrrolidine dithiocarbamate complexes were prepared and fully characterized. Reactions of the dimeric cyclopalladated complexes, [Pd(ppy)(μ-Cl)]2 (ppyH= phenylpyridine) or [Pd(N-BAZ)(μ-Cl)]2 (N-BAZH = N,N-dimethylbenzylamine) with two moles equivalent of ammonium pyrrolidine dithiocarbamate NH4(PyDT) afford [Pd(PyDT)(ppy)] and [...

The title compound, sodium ammonium sulfate dihydrate (SASD), NaNH 4 SO 4 ·2H 2 O, a synthetic analogue of the mineral lecontite, is a well known ferroelectric. The crystal structure of the paraelectric phase has been re-refined at 170 K on the basis of single-crystal X-ray data, improving the previous study [Arzt & Glazer (1994). Acta Cryst. B 50...

Treatment of molybdenum(II) chloride with the difunctional silylamide Li 2 Me 2 Si(NPh) 2 led to the formation of the tetranuclear cluster compound [Mo 4 {Me 2 Si(NPh) 2 } 4 ]. According to the X‐ray crystal structure determination, the central core of the cluster consists of four molybdenum atoms in a nearly rectangular arrangement. There are two...

Several 3-O-acetyl-platanic carboxamides were converted by an aqueous solution of sodium hydroxide to novel δ−lactams in excellent yields. These reactions proceed via an epimerization at C-19 of the platanic acid skeleton followed by a condensation reaction. The structure of the products was confirmed by extensive NMR studies and single crystal X-r...

Trans-[PdCl2(bzta)2] (bzta = 2-acetylaminobenzothiazole) (1a), trans-[PdCl2(bzmta)2] (bzmtaH = 2-acetylamino-6-methylbenzothiazole) (1b), trans-[PdCl2(bzcta)2] {bzcta = 2-acetylamino(6-chlorobenzothiazole)} (1c), cis-[PtCl2(bzta)2] (2a), cis-[PtCl2(bzmta)2] (2b) and cis-[PtCl2(bzcta)2] (2c) have synthesized and fully characterized; the molecular st...

The complexes bis(acetylacetonato-κ ²O , O ′)( N , N , N ′, N ′-tetramethylethylenediamine-κ ²N , N ′)manganese(II), [Mn(C 5 H 7 O 2 ) 2 (C 6 H 16 N 2 )], bis(acetylacetonato-κ ²O , O ′)( N , N , N ′, N ′-tetramethylethylenediamine-κ ²N , N ′)iron(II), [Fe(C 5 H 7 O 2 ) 2 (C 6 H 16 N 2 )], and bis(acetylacetonato-κ ²O , O ′)( N , N , N ′, N ′-tetra...

Treatment of molybdenum(II) acetate with thioether functionalized silylamides R2Si(NLi‐C6H4–2‐SR′)2 leads to the formation of dinuclear MoII complexes [Mo2{R2Si(NC6H4‐2‐SR′)2}2]. According to X‐ray crystal structure analyses the complexes [Mo2{Me2Si(NC6H4‐2‐SMe)2}2] and [Mo2{Ph2Si(NC6H4‐2‐SPh)2}2] comprise a Mo2‐unit which is coordinated by two μ‐κ...

For the first time, the pigment composition of basidiocarps from the Chilean mushroom Cortinarius pyromyxa was studied under various aspects like phylogeny, chemistry and antibiotic activity. A molecular biological study supports the monotypic position of C. pyromyxa in subgenus Myxacium, genus Cortinarius. Four undescribed diterpenoids, named pyro...

Phosphines react with the benzisothiazolinate (bit) paddlewheel dimer, [Ni2(m-bit)4.2H2O], resulting in sulfur-nitrogen bond scission and a series unexpected transformations leading to novel Ni(II) complexes containing 2-cyanophenylthiolate and related thiolate ligands.

Addition of sodium benzisothiazolinate, Na(bit), to metal salts MX⁠2·nH⁠2O (M=Mn, Co, Ni, Cu) affords a simple high yielding route to benzisothiazolinate-bridged paddlewheel dimers [M⁠2(μ-bit)⁠4·2H⁠2O]. Upon reaction with amines these serve as useful synthons to access benzisothiazolinate chemistry. Addition of 4-aminopyridine (4-ampy) in ethanol l...

Thioether-functionalized aminosilanes R 2 Si(NH-C 6 H 4 -2-SR′) 2 with R=Me, Ph and R′= t -Bu, Me, Ph were synthesized from the corresponding dichlorosilanes R 2 SiCl 2 and lithiated aniline derivatives LiNH-C 6 H 4 -2-SR′. Treatment of the functionalized aminosilanes R 2 Si(NH-C 6 H 4 -2-SR′) 2 with two eq. of n -BuLi and subsequent reaction with...

The trifunctional silylamine MesSi(NHPh) 3 (Mes: 2,4,6-trimethylphenyl) was prepared by standard methods from MesSiCl 3 and LiNHPh. Lithiation of MesSi(NHPh) 3 and subsequent reaction with copper(I) benzoate afforded the nonanuclear cluster complex [Cu 9 {MesSi(NPh) 3 } 2 (PhCO 2 ) 3 ]·2toluene. The cluster core consists of three copper atoms which...

A set of eight derivatives of betulinic acid (2) and 12 derivatives of platanic acid (3) has been prepared and screened for their cytotoxic activity using SRB assays. First synthetic approaches were focused on the preparation of augustic acid (4) analogs of 2 and 3 by introducing a second hydroxyl group on the A-ring of both triterpenoic acids lead...

Reactions of [Pd(Me2NCH2C6H4-κ²N,C)(μ-Cl)]2 with two equivalents of sodium saccharinate (Nasac), thiosaccharin (Htsac) or sodium benzisothiozolinate (Nabit) results in the stepwise substitution of the bridging halides to form sequentially [Pd2(Me2NCH2C6H4-κ²N,C)2(μ-Cl)(μ-X)] (X = sac, tsac) and [Pd(Me2NCH2C6H4-κ²N,C)(μ-X)]2 (X = sac, tsac, bit). Th...

The reaction of FcSeSiMe3 (Fc = Fe(η⁵-C5H5)(η⁵-C5H4)) (1) with equimolar amounts of the acid chlorides Cl(O)C-2-cC4H3X (2a, X = O; 2b, X = NMe) gave the ferrocenyl selenoesters FcSe(C(O)-2-cC4H3X) (3a, X = O; 3b, X = NMe). Upon exposure to silica gel compounds both 3a and 3b underwent an intermolecular conversion followed by transesterification wit...

Diiodido- (6a/6b) and dichloridoplatinum(II) complexes (7a/7b) with fluorescence ligands 2-[(2-aminoethyl)amino]ethyl 2-(methylamino)benzoate (5a) and 2-amino-1-(aminoethyl)ethyl 2-(methylamino)benzoate (5b) were prepared and characterized by elemental analysis, ESI-MS analysis, fluorescence spectrometry, as well as 1H, 13C and 195Pt NMR spectrosco...

Treatment of R2SiCl2 (R = Me, Ph) with 2-aminopyridine in the presence of NEt3 led to the formation of the bis(N-2-pyridylamino)silanes R2Si{NH(2-Py)}2, which were isolated as pale yellow solids. Crystal structure analyses revealed that both compounds exhibit tetrahedrally coordinated silicon atoms which are linked to two 2-pyridylamido moieties an...

A comparative study of reactions of saccharinate (sac), thiosaccharinate (tsac) and benzisothiozolinate (bit) with trans-[PdCl2(H2NBz)2] is reported. While in all cases substitution of both chlorides occurs, product types differ for the three closely related ligands. With sodium saccharinate, trans-[Pd(N-sac)2(H2NBz)2] results in which the sac liga...

A range of new cadmium(II) thiosaccharinate (tsac) complexes have been prepared from reactions of the synthon [Cd(tsac)2.H2O] with a variety of two-electron donor ligands including amino- and acetyl-amino heterocycles, 2-mercaptobenzoimidazole, 2-mercaptobenzothiozole and 2-phenylpyridine, as well as the bidentate small bite-angle diphosphane, bis(...

Pyrofomins A-D, four polyoxygenated sesquiterpenoids have been isolated from the methanolic extract of the fruit bodies of Pyrofomes demidoffii. Their structures are elucidated by IR, HR-FTICR-MS, and 2D NMR spectroscopy. Furthermore, the cedrane carbon skeleton of pyrofomin A (1) is confirmed by X-ray crystallographic analysis. The sesquiterpenoid...

Treatment of CuCl with the lithiated silyl amides RSi(NLiPh)3 (R = Me, Ph, Vin) in THF as solvent led to the formation of the novel CuI cluster compounds [Li(THF)4]2[Cu10{RSi(NPh)3}4]. For each of the three compounds the X-ray crystal structure analysis revealed similar Si4N12Cu10 cores which are based on cubane like Cu8 cores bearing two additiona...

Addition of 2-aminobenzothiazole and substituted derivatives to mercuric acetate in warm ethanol leads to the high yield formation of [Hg{SC6H3XN(C[triple bond, length as m-dash]N)}]n resulting from loss of hydrogen and sulfur-carbon bond cleavage. Addition of phosphines affords a series of complexes in which the new ortho-cyano-aminothiophenolate...

Treatment of the cluster compounds [Cp2(CO)4Mo2ESbCl] (E = S, Se) with GaCl3 in thf as solvent leads to the compounds [Cp2(CO)4Mo2ESb]GaCl4. [Cp2(CO)4Mo2SSb]GaCl4 crystallizes in the monoclinic system, space group P21/c with a = 815.64(6), b = 1094.31(5), c = 2503.7(2) pm, and β = 92.505(6)°. The selenium derivative [Cp2(CO)4Mo2SeSb]GaCl4 forms iso...

Reaction of Na-2[PdCl4] with two equivalents of amino- or acetylamino-pyridines (LH) affords trans-[PdCl2-(LH)(2)] {LH = 2-amino-3-methylpyridine (2-ampyH), 3-aminopyridine (3-apyH), 2-acetylamino-3-methylpyridine (2-acmpyH), 3-acetylamino-pyridine (3-acpyH)}. An X-ray crystal structure of trans-[PdCl2(2-ampyH)(2)] shows that the 2-ampy-H ligands a...

Treatment of copper(I) chloride with R2Si(NLiPh)2 (R = Me, Ph) in thf led to the formation of the octanuclear cluster compounds [Cu8{(R2Si(NPh)2}4] [R = Me (1), Ph (2).] Compound 1 crystallizes in the tetragonal space group P4/n, with a = 1505.41(5) and c = 1911.32(7) pm. The X-ray crystal structure determination revealed a cube shaped Cu8 cluster...

The new platinum(II) complexes cis-[Pt(sac)2(NH3)2] (sac = saccharinate) and cis-[Pt(tsac)2(NH3)2] (tsac = thiosaccharinate) have been prepared, the X-ray crystal structure of cis-[Pt(sac)2(NH3)2].H2O reveals that both saccharinate anions are N-bound in a cisarrangement being inequivalent in both the solid-state and in solution at room temperature....

X-Ray diffraction analysis of 1-methyl-2-thiocytosine (1-MeSCy, 1) revealed that its crystals contain two structurally very similar independent molecules (A, B). These molecules are connected through a complex network of hydrogen bonds. Centrosymmetric di- and tetrameric units AAʹ and BAAʹBʹ, respectively, are formed through N-H...N hydrogen bonds...

A previously unknown dimer of the well-established analgesic flupirtine has been found, and its structure was revealed by ESI-MS, NMR spectroscopy and an independent synthesis. Thus, starting from 2-amino-6-chloro-3-nitro-pyridine the target compound was obtained in a four-step synthesis. Key-step of this synthesis is a nickel-mediated aryl-aryl co...

II) saccharinate (sac) and thiosaccharinate (tsac) complexes with supporting amino-and acetylamino-thiazole ligands: Crystal structures of trans-[PdCl 2 (abzt) 2 ]Ádmf (abzt = 2-aminobenzothiazole), trans-[PdCl 2 (bzta) 2 ].dmf (bzta = 2-acetylaminobenzothiazole) and trans-[Pd(sac) 2 (abzt) 2 ]Á2dmf a b s t r a c t Treatment of Na 2 PdCl 4 with two...

C48H42ClIrO8P2, orthorhombic, P212121 (No. 19), a = 21.146(3) Å, b = 11.198(2)Å, c= 18.200(4)Å, V=4309.6Å3, Z = 4, Rgt(F) = 0.021, wRref(F2) = 0.040, T=220 K.

Three novel chiral Schiff Base ligands (H2L) were prepared from the condensation reaction of 3‐formyl acetylacetone with the amino acids L‐alanine, L‐phenylalanine, and L‐threonine. X‐ray single crystal analyses revealed that the Schiff Base compounds exist as enamine tautomers in the solid state. The molecular structure of the compounds is stabili...

The reaction of the platina-β-diketone [Pt2{(COMe)2H}2(μ-Cl)2] (1) with quinoline-8-carbaldehyde (C9H6NCHO) in MeOH/H2O (Pt/C9H6NCHO = 1/2) leads to the cleavage of the chloride bridges in 1 with acetaldehyde displacement and to the formation of the acetylacyl(hydroxyalkyl)platinum(IV) complex [Pt(COMe)Cl(C9H6NCO-κN,κC)(C9H6NCHOH-κN,κC)] (3) as a s...

The dinuclear platina-β-diketone [Pt2{(COMe)2H}2(μ-Cl)2] (1) reacted with 2-pyridyl-functionalized monoximes and with dioximes in the presence of NaOMe to yield oxime–diacetyl platinum(II) complexes [Pt(COMe)2(2-pyCR═NOH)] (R = H, 4a; Me, 4b; Ph, 4c) and [Pt(COMe)2(HON═CR–CR═NOH)] (R/R = Me/Me, 5a; Ph/Ph, 5b; (CH2)4, 5c; NH2/NH2, 5d), respectively....

The difunctional aminosilanes Ph2Si(NHCH2CH2NMe2)2 (1), Me2Si(NHCH2CH2NiPr2)2 (2) and Ph2Si(NHCH2CH2NiPr2)2 (3) were prepared by aminolysis of the chlorosilanes R2SiCl2 (R = Ph, Me) and the corresponding ethylenediamine derivatives H2NCH2CH2NR'2 (R' = Me, iPr). The trifunctional aminosilane MeSi(NHCH2CH2NiPr2)3 (4) was synthesized from MeSiCl3 and...

Simple palladium(II) and platinum(II) complexes, ML2 (1–2), of N-phenyl-(2-thiazoyl)thiourea have been prepared and fully characterized. The structure of Pd(S2N3C10H8)2 (1) is monoclinic P21/c, a = 12.510(2), b = 5.6963(6), c = 15.322(2) Å, b = 90.07(2)o and Pt(S2N3C10H8)2 (2) is orthorhombic P2 1 2 1 2 1 , a = 7.3021(5), b = 11.8025(9), c = 25.628...

A previously unknown dimer of the well-established analgesic flupirtine has been found, and its structure was revealed by ESI-MS, NMR spectroscopy and an independent synthesis. Thus, starting from 2-amino-6-chloro-3-nitro-pyridine the target compound was obtained in a four-step synthesis. Key-step of this synthesis is a nickel-mediated aryl-aryl co...

In the title compound, [Na(C(6)H(5)NH)(C(4)H(10)O(2))], the Na(+) cation is coordinated by the N atoms of two anilide anions, two O atoms of a chelating 1,2-dimeth-oxy-ethane (dme) ligand and one O atom of an adjacent dme ligand. The coordination polyhedron around Na(+) corresponds to a distorted square pyramid with the N atoms of the anilide group...

Treatment of [MCl2(κ2-dppf)] (M = Pd or Pt) with two equivalents of potassium heterocyclic thionate salts (KL) affords mixed ligand complexes [ML2(κ2-dppf)] [L = 5-phenyl-1,3,4-oxadiazole-2-thionate (Phozt), 4,5-diphenyl-1,2,4-triazole-3-thionate (Ph2tzt), benz-1,3-thiazoline-2-thionate (bztzt) and benz-1,3-oxazoline-2-thionate (bzoxt)]. X-ray stru...

The Zeise's salt type cyclooctyne compound [K(18C6)][PtCl(3)(COC)] (1; COC = cyclooctyne; 18C6 = 18-crown-6) was found to react in chloroform solution at room temperature within several weeks yielding the dinuclear cyclooctadiene compound [K(18C6)](2)[(PtCl(3))(2)(μ-η(2):η(2)-1,3-COD)] (2; 1,3-COD = cycloocta-1,3-diene) and non-coordinated cyclooct...

In the title compound, [Sn(C(6)H(5))(3)(C(10)H(13)OS)]·0.17C(6)H(6), the Sn(IV) atom exhibits a slightly distorted tetra-hedral coordination geometry built up by four C atoms, which are the three ipso-C atoms of the phenyl rings and the α-C atom of the deprotonated γ-O-functionalized propyl phenyl sulfide. The benzene mol-ecule lies about a threefo...

The title compound, C(6)H(8)NO(3)P, is isostructural with p-arsanilic acid. It exists as the zwitterion H(3)N(+)C(6)H(4)PO(3)H(-). In the crystal, mol-ecules are linked by O-H⋯O and N-H⋯O hydrogen-bond bridges, giving a three-dimensional network structure. The strongest hydrogen bonds are formed between adjacent PO(3)H groups with O⋯O distances of...

The title compound, C6H8NO3P, is isostructural with p-arsanilic acid. It exists as the zwitterion H3N+C6H4PO3H−. In the crystal, mol­ecules are linked by O—H⋯O and N—H⋯O hydrogen-bond bridges, giving a three-dimensional network structure. The strongest hydrogen bonds are formed between adjacent PO3H groups with O⋯O distances of 2.577 (2) Å.

The reaction of ECl3 (E = Al, Ga) with two equivalentsof Li2Me2Si(NPh)2 (in diethyl ether/n-hexane) leads to the formation of bis-chelate complexes [Li(OEt2)3][E{Me2Si(NPh)2}2] (E = Al (1), Ga (2)). Compounds 1 and 2 crystallize isotypically in the monoclinic system with a = 1136.42(6), b = 3267.9(1), c = 1360.37(8) pm, β = 94.320(7)° for 1 and a =...

Zeise’s type alkyne complexes [K(18C6)][PtCl3(RC≡CR′)] (R/R′ = Me/Me, 3; Et/Et, 4; Me/t-Bu, 5; t-Bu/t-Bu, 6; Me/Ph, 7; Me/CO2Me, 8; RC≡CR′ = COC, 9; COC = cyclooctyne; 18C6 = 18-crown-6) were obtained from the cis-but-2-ene complex [K(18C6][PtCl3(cis-but-2-ene)] (2) and the requisite alkyne via a ligand substitution reaction. 1H NMR spectroscopical...

In the title compound, [Pd(C5H8NO4)2], the Pd(II) atom is coordinated by two O atoms and two N atoms of two N,O-chelating hydrogen l-glutatmate ligands in a square–planar geometry with the N and O atoms in a mutually trans arrangement. The complex units are embedded in a network of N—H⋯O and O—H⋯O hydrogen-bonding inter­actions that stabilize the t...

Rhodium(I) complexes of type I bearing κP coordinated ω-phosphinofunctionalized alkyl phenyl sulfide (x = 0), sulfoxide (x = 1) and sulfone (x = 2) ligands Ph2P(CH2)nS(O)xPh (n = 1–3) were found to react with Ag[BF4] to yield cationic complexes of type II. Furthermore, addition of sodium bis(trimethylsiliyl)amide to complexes of type I afforded zwi...

Reaction of [{Cp(CO)3Mo}2SbCl] with S8 or Se8 leads to the formation of cluster compounds [{Cp(CO)2Mo}2ESbCl] (E = S, Se). [{Cp(CO)2Mo}2SSbCl] crystallizes monoclinic, space group P21/n with a = 812.28(3), b = 855.65(4), c = 2441.01(9) pm and β = 90.149(3)°; [{Cp(CO)2Mo}2SeSbCl]·CH2Cl2 crystallizes triclinic, space group P with a = 828.82(9), b = 1...

The reaction of the electronically unsaturated platina-β-diketone [Pt2{(COMe)2H}2(μ-Cl)2] (1) with Ph2PCH2CH2CH2SPh (2) leads selectively to the formation of the acetyl(chlorido) platinum(II) complex (SP-4-3)-[Pt(COMe)Cl(Ph2PCH2CH2CH2SPh-κP,κS)] (4) having the γ-phosphinofunctionalized propyl phenyl sulfide coordinated in a bidentate fashion (κP,κS...

The crystal structures of potassium and silver cyanamidonitrate are reported. In both the potassium and the silver salt metal anion contacts via the atoms cyano-N, amide-N and oxygen are observed. The structural parameters of the ion [NO2NCN] are only slightly influenced by the different environments (potassium, silver). K[NO2NCN] forms a coordinat...

Investigations of the metabolic conversion of the phytohormone 24-epicastasterone ( 1 ) in the cockroach Periplaneta americana (L.) required the synthesis of 2,24-diepicastasterone ( 4 ), 3,24-diepicastasterone ( 7b ) and 2-dehydro-3,24-diepicastasterone ( 9 ) as reference standards. 2,24-Diepicastasterone ( 4 ) was synthesized from 2α,3α-epoxy der...

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.

In the title hydrate, [Fe(2)Sn(C(5)H(5))(2)(OH)(2)(CO)(4)]·H(2)O, the central Sn atom is tetra-hedrally coordinated by two {Cp(CO)(2)Fe} fragments and two hydroxide groups. The [{Cp(CO)(2)Fe}(2)Sn(OH)(2)] and water mol-ecules are linked by O-H⋯O hydrogen bridges, giving two-dimensional arrays with 4.8(2) topology that stack along the c axis.

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Reactions of dinuclear chloridorhodium(I) complexes [(RhL₂)₂(μ-Cl)₂] (L₂ = P[symbol: see text]P: Me₂P(CH₂)₂PMe₂, dmpe, 7a; Ph₂PCH₂PPh₂, dppm, 7b; Ph₂P(CH₂)₂PPh₂, dppe, 7c; Ph₂P(CH₂)₃PPh₂, dppp, 7d; L₂ = cycloocta-1,5-diene, cod, 5) with lithiated γ-phosphino- and γ-aminofunctionalized propyl phenyl sulfones (Li[CH(SO₂Ph)CH₂CH₂PPh₂], 2; Li[CH(SO₂Ph)...

Treatment of MSO4·7H2O (M = Fe, Co, Zn) with Ba(Hsb)2·3H2O (Hsb = 4-carboxylbenzenesulfonate) under hydrothermal conditions led to the formation of the corresponding 4-carboxylbenzenesulfonates [M(H2O)6](Hsb)2 [M = Fe (1), Co (2), Zn (3)]. The compounds crystallize triclinic in the space group P\bar{1} with the lattice parameters (at 220 K) a = 544...

In the title hydrate, [Pt(CH(3))(3)(CH(3)COO)(C(10)H(8)N(2))]·H(2)O, the Pt(IV) atom exhibits a distorted octa-hedral coordination geometry built up by three methyl ligands in a facial arrangement, a bipyridine ligand and a monodentately bound acetate ligand. In the crystal structure, inter-molecular O-H⋯O hydrogen bonds are observed between the wa...

The reaction of [PtMe3(bpy)(Me2CO)](BF4) (2) (prepared from [PtMe3I(bpy)] (1) plus Ag(BF4)) with MeSSMe resulted in the formation of [PtMe3(bpy)(MeSSMe-κS)](BF4) (3). A single-crystal X-ray diffraction analysis revealed in the octahedral Pt(IV) complex (configuration index: OC-6-33), a conformation of the monodentately κS bound MeSSMe ligand (C–S–S...

In the title hydrate, [Pt(CH3)3(CH3COO)(C10H8N2)]·H2O, the PtIV atom exhibits a distorted octahedral coordination geometry built up by three methyl ligands in a facial arrangement, a bipyridine ligand and a monodentately bound acetate ligand. In the crystal structure, intermolecular O—H...O hydrogen bonds are observed between the water molecule and...

In the title hydrate, [Fe2Sn(C5H5)2(OH)2(CO)4]·H2O, the central Sn atom is tetrahedrally coordinated by two {Cp(CO)2Fe} fragments and two hydroxide groups. The [{Cp(CO)2Fe}2Sn(OH)2] and water molecules are linked by O—H...O hydrogen bridges, giving two-dimensional arrays with 4.82 topology that stack along the c axis.

The platina-β-diketones [Pt2{(COMe)2H}2(μ-Cl)2] (1), [PPh4][Pt{(COMe)2H}Cl2] (2) and [Pt{(COMe)2H}-(acac)] (3) were found to catalyze the hydrosilylation of alkynes (hex-1-yne, hex-2-yne, hex-3-yne) and alkenes (hex-1-ene, styrene, trimethylvinylsilane) with methyldiphenylsilane (nsilane:nsubstrate:nPt=3000:3000:1, T=27°C, in C6D6). The comparison...

Reactions of the platinum(IV) complexes [PtMe(3)(OCMe(2))(3)](BF(4)) (1(BF(4))), [(PtMe(3)I)(4)] (2), and [PtMe(3)I(py)(2)] (3) with the N,N-heterocyclic carbene 1,3-dimethylimidazol-2-ylidene (N,N-hc, 4) resulted in a rapid reductive elimination of ethane, yielding platinum(II) complexes [PtMe(N,N-hc)(3)](+) (7), trans-[PtMeI(N,N-hc)(2)] (8), and...

The bis(acetyl)-bridged complex [{Pt(COMe)2}n] (2) has been prepared from the platina-β-diketone [Pt2{(COMe)2H}2(μ-Cl)2] (1) with hexamethyldisilazane. Reactions of complex 2 with the monodentate P and N donors PPh3, pyrazole (Hpz), pyridine (py), 4-methylpyridine (4-Mepy), and benzylamine (BnNH2) resulted in the formation of the cis-diacetylplatin...

The reaction of K2[PdCl4] with (S,S)-(i-Pr)2eddip diester (diiso-propyl (S,S)-2,2’-(1,2-ethanediyldiimino)dipropanoate) resulted in {PdCl2[(S,S)-(i-Pr)2eddip-κ2N,N’]} (1) and {PdCl[(S,S)-(i-Pr)eddip-κ2N,N’,κO]} (2) with one hydrolyzed ester group. The compounds were characterized by spectroscopic methods and it was proved that the reaction is diast...

A number of complexes of the types [PtBr2Me2(N⌢N)] (N⌢N=4,4′-di-Me-2,2′-bpy (1); 4,4′-di-t-Bu-2,2′-bpy (2); 2,2′-bpz (3); bpym (4)) and [PtBr2Me2(L)2] (L=H-pz (5); 4-Me-H-pz (6); H-idz (7); H-im (8); H-bim (9); quaz (10)) are reported. Characterization by NMR (1H, 13C and 195Pt), IR and EI-MS is given. In addition, crystal structures of several of...

Diacetylplatinum(II) complexes [Pt(COMe)2()] (=bpy, 3a; 4,4′-t-Bu2-bpy, 3b), obtained by the reaction of [Pt(COMe)2X(H)()] with NaOH in CH2Cl2/H2O, were found to undergo oxidative addition reactions with halogens (Br2, I2) yielding the platinum(IV) complexes (trans, OC-6-13)/(cis, OC-6-32) [Pt(COMe)2X2()] (=bpy, X=Br, 4a/4b; I, 4c/4d; =4,4′-t-Bu2-b...

The reaction of [PtMe3(MeOH)(bpy)][BF4] (1) with the thionucleobases 2-thiocytosine (SCy, 2) and 1-methyl-2-thiocytosine (1-MeSCy, 3) resulted in the formation of the complexes [PtMe3(bpy)(SCy-κS)][BF4] (4) and [PtMe3(bpy)(1-MeSCy-κS)] [BF4] (5), respectively. The complexes were characterized by 1H and 13C NMR spectroscopy as well as by single-crys...