Chinedum Ogbonnaya Eleazu

Federal University Ndufu Alike Ikwo | FUNAI · Department of Chemistry/Biochemistry/Molecular Biology

Objective: The effect of Syzygium malaccense methanol leaf extract (SMLE) on some parameters of testosterone-estradiol valerate induced benign prostatic hyperplasia (BPH) in rats was assayed. Materials and Methods: Thirty male albino rats were used and they were grouped as: Control: received 1 mL/kg olive oil (oral and subcutaneous); BPH: received...

The effect of different doses of unripe plantain or their combinations with ginger (25 g/kg) on some parameters in streptozotocin (STZ)-induced diabetic rats was studied. Following diabetes induction, 45 male albino rats were divided into nine groups of five rats each: groups 1 and 2 (control and diabetic) received rat pellets, group 3 received 200...

ANTI-LIPOMA POTENTIAL OF FRESH PALM FRUITS EXTRACT 3Okorie Uchechukwu, 1,2Uro-Chukwu Henry Chukwuemeka, 3Eleazu Chinedum Ogbonna 1National Obstetric Fistula Centre, Abakaliki, Ebonyi State, Nigeria 2Institute for Nutrition, Nutraceutical & Public Health Research & Development, Nigeria, 3Department of Biochemistry, Alex-Ekwueme Federal University Nd...

Background: It has been observed that most malaria patients especially G6PD-deficient patients usually experience oxidative stress and severe anemia when treated with primaquine. This calls for the need to search for a treatment option that will ameliorate these side effects. Objective: The effect of co-treatment of malaria with aqueous extract of...

The effect of 21% fructose drinking water (FDW) (w/v) on some parameters of metabolic syndrome, hepatic, and skeletal muscular histology of rats was studied using standard techniques. Twenty male albino rats were divided into four groups of 5 rats each in this in vivo study. Group I received distilled water, group 2 received FDW, group 3 received F...

The burden of ischemic heart disease in Nigeria calls for an evidence-based, innovative, and interdisciplinary approach towards decreasing health inequalities resulting from individual lifestyle and poor socioeconomic status in order to uphold the holistic health of individuals to achieve global sustainability and health equity. The poor diagnosis...

Obesity, a disorder of body weight regulatory systems that is characterized by the accumulation of excess body fat is increasingly becoming a global pandemic. Despite several approaches that have been applied to mitigate obesity, they have not been able to totally reverse the obesity and its mediated complication. Advanced glycation end products (A...

Purpose This study aims to report the phytochemical screening and anti-diarrhoea properties of methanol extract of Diodia sarmentosa Swartz (DSS) leave (at 200, 400 and 600 mg/kg) in albino rats. Design/methodology/approach Three types of diarrhoea models (castor oil-induced diarrhoea, castor oil-induced gastrointestinal motility and castor oil-in...

Background: The pituitary-gonadal axis plays an important role in steroidogenesis and spermatogenesis and by extension, fertility. Objectives: The aim of this study was to investigate the protective role of bee bread, which is a natural bee product, against obesity-induced decreases in steroidogenesis and spermatogenesis. Methods: Thirty-two a...

Purpose – This study aims to design to assess the traditional, complementary and alternate medicine (TCAM) usage and its association with the quality of life (QOL) of Type 2 diabetic patients in a tertiary hospital (Hospital Universiti Sains Malaysia) in Malaysia. Design/methodology/approach – A total of 300 respondents included in this study were...

Anaemia is a serious health challenge in developing countries. This study evaluated the chemical composition of Combretum dolichopetalum (CD) leaves, the effect of its methanol extract on the body weights and haematological indices of phenylhydrazine induced-anaemic rats. Fresh matured leaves of CD were collected, identified and authenticated. Phyt...

Doxorubicin (DOX) is a broad-spectrum chemotherapeutic drug used in the treatment of cancers. It acts by generating reactive oxygen species in target cells. The actions are, however, not limited to cancerous cells as it attacks healthy cells, killing them. This study investigated the benefits of the antioxidant, tert-butylhydroquinone (tBHQ), on te...

The increased global prevalence of benign prostatic hyperplasia (BPH) and the promising potentials of functional foods in ameliorating it led to this study which reported the effect of aqueous ethanol extract of cocoyam (Colocasia esculenta) tuber on some biochemical indices in testosterone propionate (TP) induced benign prostatic hyperplasia (BPH)...

The effect of bee bread (BB) on the biochemical parameters—body weights, calorie intake, Lee obesity indices, serum amylase, aspartate and alanine amino transferases, skeletal muscle activities of creatine kinase, superoxide dismutase, glutathione peroxidase, catalase, malondialdehyde, glutathione‐S‐transferase, total antioxidant activity, endogeno...

This study reported the chemical composition of Tualang honey and its effect on the lung surfactants and histology of male rats exposed to cigarette smoke. Thirty-two adult male Sprague-Dawley rats were used and they were randomly divided into 4 groups of eight rats each: control, honey-treated (Honey), cigarette smoke-exposed (CS) and honey-treate...

The effect of processing on the proximal, amino acid, micro-and macromineral, heavy metal, vitamin, antinutrient, and phenolic profiles of maize (Zea mays) was investigated using standard techniques. Boiling decreased the total amino acid content unlike frying and roasting, but they did not affect the total phenolic content of maize. Boiling increa...

Options currently being used for the treatment of obesity abound, however, few have successfully and sustainably reversed the disease and its comorbidities. This has led to the search for alternative approaches. Targeting of the signaling of the soluble and endogenous secretory receptors for advanced glycation end products (sRAGE and esRAGE) could...

We studied the acute and sub-acute toxicity of Combretum dolichopetalum leaves in experimental mice and rats respectively using standard techniques. The LD50 of the methanol extract of Combretum dolichopetalum leaves as carried out in experimental mice was obtained as more than 5000 mg/kg body weight. Administration of graded doses (100, 200, 400 a...

Oxidative stress, chronic inflammation and apoptosis are associated with obesity. Herein, we investigated the potential protective effect of bee bread, a natural bee product, on testicular oxidative stress, inflammation and apoptosis, as well as lactate transport in the testis of high-fat diet (HFD)-induced obese rats. Adult male Sprague-Dawley rat...

Context: Global prevalence of obesity is increasing. Objective: To study the effect of bee bread (BB) on serum renal function parameters, oxidative stress, inflammatory and B-cell associated protein X (Bax) in the kidneys of high fat diet (HFD) obese rats. Methods: Thirty-six male Sprague Dawley rats were used. Control: received rat diet and w...

Cyclophosphamide is an alkylating anticancer agent with strong efficacy; however, its clinical use is constrained because of its off-target multiple organ toxicity, and one of them is testicular injury. We assayed to explore whether garlic oil (GO) could prevent cyclophosphamide (CYP)-induced testicular oxidative stress and hormonal deficit in male...

Oxidative stress, inflammation and apoptosis are major complications that trigger organ failure in diabetes mellitus (DM), and are proven to adversely affect the male reproductive system. Clinical and experimental studies have demonstrated the promising protective effects of propolis in DM and its associated systemic effects. Herein, we investigate...

Zinc abrogates anticancer drug tamoxifen-induced hepatotoxicity by suppressing redox imbalance, NO/iNOS/NF-ĸB signalling and caspase-3-dependent apoptosis in female rats Abstract Tamoxifen (TAM) is used in breast cancer chemotherapy since its approval by the Food and Drug Administration in 1977. However, TAM therapy is accompanied with hepatotoxici...

[This corrects the article DOI: 10.3389/fphys.2019.00787.].

Obesity, a chronic multifaceted disease, predisposes its patients to increased risk of metabolic disorders such as: diabetes mellitus, cardiovascular diseaseas, dyslipidemia, etc. Recent studies reported it to be amongst the leading causes of deaths in the world. Although several treatment options for obesity abound, many of them have not been able...

The nutrients, heavy metals and pesticide concentrations of an imported (Gold) and three locally produced and marketed rice varieties (Samples B-mass, C-R8 and D-CP) in Nigeria were investigated using standard techniques. All the rice varieties contained considerable amounts of moisture, ash, protein, lipid and carbohydrate but were low in crude fi...

Background: Research studies that holistically investigated the effect of administration of virgin coconut oil (VCO) on diabetic humans or animals are limited in literature. Objective: To investigate the effect of administration of VCO on lipid profile, markers of hepatic and renal dysfunction, and hepatic and renal antioxidant activities of all...

The proximate, phytochemical, mineral and vitamin composition of the processed urena lobata leaves were analyzed using Association of Official Analytical Chemist (AOAC) method, Arisa, Onwuka, Pearson, Harboure ,and Atomic Absorption spectrophotometry, Okwu and Josiah procedures respectively. This study is aimed at investigating the nutrition and an...

The effect of cooking (boiling) on the starch digestibility, polyphenol contents and in vitro α-amylase inhibitory properties of two varieties of cocoyam: Colocassia esculenta (taro) and Xanthosoma mafafa (Tania) were investigated. The total starch contents of the raw and cooked tubers ranged from 25.3 to 35.6 g 100 g−1; resistant starch ranged fro...

The incidence of type 2 diabetes mellitus (T2DM) has been on the increase in recent times. Although several oral treatments for T2DM are available, some of them have been found to elicit undesirable side effects. This therefore underscores the need for new treatment options with lesser side effects than the existing ones for people with T2DM. Free...

Background: There is a paucity of information in the literature on the effect of Cnidoscolus aconitifolius on the hematological, coagulation activities, electrolyte balance and antioxidant activities of humans or animals. Objectives: To determine the ameliorative potentials of methanol fractions of Cnidoscolus aconitifolius on hematological, coagul...

The effect of ethanol extracts of boiled Treculia africana seed on the oral glucose tolerance (OGTT), lipid profile, and body weight of normoglycemic albino rats was determined. Fifteen male albino rats were used and were divided into three groups of five rats each. Groups 1 and 2 received 100 and 200 mg/kg of the extract, while group 3 (control gr...

The effect of processing on the biochemical contents of Acanthus montanus leaves was investigated. The moisture, crude protein, lipid, fiber, ash, and total carbohydrate contents of the raw vegetable were 59.15, 1.85, 2.32, 3.76, 2.04, and 34.65 g/100 g, respectively. The saponin, alkaloid, tannin, flavonoid, phenol, and anthocyanin contents of the...

The effect of cooking on starch hydrolysis, polyphenol contents, and in vitro α-amylase inhibitory properties of mushrooms (two varieties Russula virescens and Auricularia auricula-judae), sweet potato (Ipomea batatas), and potato (Solanum tuberosum) was investigated. The total, resistant, and digestible starch contents of the raw and cooked food s...

The total and free cyanide levels in fresh peels, pulps and leaves of three cassava (Manihot escu-lenta Crantz) varieties: TMS 01/1368 (UMUCASS 36), TMS 01/1412 (UMUCASS 37) and TMS 01/1371 (UMUCASS 38) were determined using standard enzymatic methods. Results showed that the total cyanide levels in the peels, pulps and leaves of these cassava vari...

The effect of processing on starch digestibility, predicted glycemic indices (pGI), polyphenol contents and alpha amylase inhibitory properties of beans (Phaseolis vulgaris) and breadfruit (Treculia africana) was studied. Total starch ranged from 4.3 to 68.3 g/100 g, digestible starch ranged from 4.3 to 59.2 to 65.7 g/100 g for the raw and processe...

The incidence of benign prostatic hyperplasia (BPH) is gradually on the increase. While conventional drugs such as the α1-adrenergic receptor antagonists and 5α-reductase inhibitors have been found to be useful in the treatment of BPH, the adverse side effects associated with their usage, have led to increased search for alternative means of managi...

Background. Although African breadfruit (Treculia africana) is said to be useful in the dietary management of diabetes, the effect of cooking on its glycemic index has not been reported. Hence this study has investi- gated the effect of a dietary intake of boiled breadfruit on the serum glucose, glucose tolerance, body weights and relative organ we...

The incidence of erectile dysfunction (ED) is on the increase and it is estimated that it will affect about 322 million men globally by the year 2025 if adequate measures are not taken to curb it. Natural polyphenols in plant based diets have gained public interest in recent times due to their roles in the prevention of various disease that implica...

Background: No study to date has investigated the effect of different polar solvent extracts from Cnidoscolus aconitifolius leaves on glycemic control as used in folk medicine. Hence this study which investigated the effect of ethanol extract and fractions of C. aconitifolius leaves on body weights, relative organ weights, serum levels of glucose,...

This study investigated the effect of fractions of kolaviron on some biochemical parameters in benign prostatic hyperplasia (BPH) rats and also characterized the most active fraction (F1) using GC-MS. BPH was induced in the rats by sub-cutaneous injection of dihydrotestosterone and estradiol valerate (10 : 1) daily for 28 days. Rats were euthanized...

The starch digestibility, α-amylase and α-glucosidase inhibitory capacities of the flours from raw and processed (boiled and fried) tubers of three varieties (riyom, beebot and langaat) of P. esculenta were investigated using standard techniques. The range of the chemical constituents of the flours (expressed in g/100 g, dry weight) were: lipids (0...

Background: This article examines the concepts of low glycemic indices (GIs) and glycemic load (GL) foods as key drivers in the dietary management of type 2 diabetes as well as their shortcomings. The controversies arising from the analysis of glycemic index (GI) and GL of foods such as their reproducibility as well as their relevance to the dieta...

Context: There is paucity of information in literature on the natural products in cocoyam [Colocasia esculenta Linn (Araceae)] that confer it with biological properties. Objectives: This study investigated the antioxidant properties of C. esculenta and also reported for the first time the natural products in C. esculenta that justify its biological...

The metabolism of yellow cassava (variety TMS 01/1368) was investigated in male albino rats fed a diet containing yellow cassava for 7 to 28 days. There were significant increases (P < 0.05) in total and free cyanide and thiocyanate in the sera and urine samples of the experimental rats compared with the control, significant increases (P < 0.05) in...

The nutrients, natural products and antioxidant capacity of flour from Living-stone potato (Plectranthus esculentus) tubers were investigated. The flour contained 8.26 ± 0.20% moisture, 2.58 ± 0.18% ash, 2.60 ± 0.07% dietary fiber, 5.30 ± 0.17% lipid, 7.87 ± 0.04% protein and 76.00 ± 2.33% carbohydrate, but contained low amount of thiamine, ribofla...

The bioactive constituents and antioxidant activities of raw, fried and decoctions of cocoyam (Colocasia esculenta) tubers were investigated. The raw form contained considerable amounts of proximates, phytochemicals, minerals, vitamins, amylose, amylopectin and antioxidants (determined from carotenoid, reducing power and 2,2 diphenyl-1-picryl hydra...

In Michael Okpara University of Agriculture, Umudike, Nigeria (MOUAU) and surrounding environments, table water of different brands is commercially hawked by vendors. To the best of our knowledge, there is no scientific documentation on the quality of these water samples. Hence this study which evaluated the quality of different brands of water sam...

The bioactive constituents and antioxidant activities of raw, fried and decoctions of cocoyam (Colocasia esculenta) tubers were investigated. The raw form contained considerable amounts of proximates, phytochemicals, minerals, vitamins, amylose, amylopectin and antioxidants (determined from carotenoid, reducing power and 2,2 diphenyl-1-picryl hydra...

The total protein, calcium (Ca), magnesium (Mg), potassium (K), sodium (Na), phosphorous (P), zinc (Zn), copper (Cu) and lead (Pb) composition of the peels of unripe plantain, ripe plantain, unripe banana and ripe banana were investigated using standard techniques. All the peel samples studied contained considerable amounts of Ca, Mg, K, Na, P, Zn,...

The possibility of combining unripe plantain [Musa paradisiacae Linn (Plantaginaceae)] and cocoyam [Colocassia esculenta Linn (Araceae)] in the management of diabetes has not been investigated. The objective of this study is to evaluate the antihyperglycemic and antihyperlipidemic actions of unripe plantain and cocoyam. Diabetes was induced in rats...

The phytochemical composition and antioxidant capacities of 6 new NRCRI turmeric (Curcuma longa L) accessions (39, 35, 60, 30, 50 and 41) were determined using standard techniques. The moisture contents of the tumeric samples ranged from 15.75 to 47.80% and the curcumin contents of the turmeric samples fell within the range of curcumin obtained fro...

Although unripe plantain (Musa paradisiaca) and ginger (Zingiber officinale) are used as single plants to manage diabetes mellitus in Nigeria, the possibility of combining them in a typical diabetic diet and the glycemic response elicited as a result of such combination has not been investigated. To determine the effect of unripe plantain and ginge...

This study aims to investigate the effect of unripe plantain (Musa paradisiaca) on markers of hepatic dysfunction in streptozotocin induced diabetic rats. Blood glucose; relative liver weight (RLW); relative kidney weight (RKW); relative heart weight (RHW); relative pancreatic weight (RPW); serum and hepatic serum aspartate transaminase (AST), alan...

To determine the effect of unripe plantain (Musa paradisiaca) and ginger (Zingiber officinale) on blood glucose (BG), feed intake (FI) and weight of streptozotocin (STZ) induced diabetic rats. Twenty four male albino rats were used and were divided into 4 groups of 6 rats each. Group 1 (non-diabetic) and Group 2 (diabetic) received standard rat fee...

The effect of livingstone potato (Plectranthus esculenthus N.E.Br) on serum glucose, glycated hemoglobin (HbA1C), serum triglyceride, total cholesterol, high density lipoprotein (HDL), low density lipoprotein (LDL), very low density lipoprotein (VLDL), hepatic malic enzyme (ME), isocitrate dehydrogenase (IDH) and catalase activities of Streptozotoc...

Background The effect of livingstone potato (Plectranthus esculenthus N.E.Br) on diabetes and its complications in Streptozotocin induced diabetic rats was investigated. The duration of the experiment was 4 weeks.Methods The blood glucose level of the rats was measured with a glucometer, the protein and glucose and specific gravity in the urine sam...

Objective: To investigate the biochemical basis of the anti-diabetic action of cocoyam [Colocassia esculenta (C. esculenta)] in streptozotocin diabetic rats. Methods: Blood glucose of the rats was measured with a glucometer. The relative heart weight, relative pancreatic weight, serum proteins, urea, creatinine, albumin, amylase, lipase, serum and...

Context: To determine the effect of Livingstone potato (Plectranthus esculentus N.E.Br) on hepatic G6PD in streptozotocin induced diabetic rats. Methods: The G6PD activities in the liver homogenates of the rats and chemical analysis of the test feeds were determined using standard techniques. Results: The diabetic control rats had significant...

Background: The aim of the paper was to compare the food qualities of 2 varieties (SME 1 and 2) of high quality cassava flour (HQCF) produced from indigenous technology and that of some commercially sold wheat/HQCF samples. Material and methods: The pH, proximate, phytochemical, antioxidant, functional properties and starch yield of the flours w...

In many countries of the world, much attention has been paid to find novel types of natural anti-diabetic drugs from various medicinal plants due to their effectiveness, limited side effects and relatively low costs. This search for novel plants that could be useful in the management of diabetic complications led to the study of the effect of livin...

IN THE CURRENT STUDY, WHEAT FLOUR WAS MIXED WITH HIGH QUALITY CASSAVA FLOUR (HQCF) IN SEVERAL RATIOS: 90:10, 80:20, 70:30, and 60:40, and used to prepare 10%, 20%, 30%, and 40% National Root Crops Research Institute (NRCRI) cassava bread, respectively. 100% wheat bread was prepared as a control (100% wheat bread). Five bread samples were prepared p...

Objective To investigate the ameliorating potentials of cocoyam (Colocasia esculenta (C. esculenta) L.) and unripe plantain (Musa paradisiacae (M. paradisiacae) L.) incorporated feeds on renal and liver growth of STZ induced rats.Methods The blood glucose level of all the rats was measured with a glucometer, the protein and glucose levels in the ur...

Streptozotocin (STZ) (2-deoxy-2-({[methyl(nitroso)amino]carbonyl}amino)-beta-D-glucopyranose) is a naturally occurring diabetogenic compound, produced by the soil bacterium streptomyces achromogenes, that exhibits broad spectrum of antibacterial properties. Streptozotocin functions as a DNA synthesis inhibitor in both bacterial and mammalian cells....

Objective To investigate the effect of Gnetum africanum on its pharmacopotency as well as its nutritional properties. Methods The total chlorophyll, carotenoids, proximates, phytochemicals, minerals, vitamins as well as antioxidant assays were performed using standard techniques. Results The raw leaves of the vegetable (Gnetum africanum) possesse...

The phenolic composition and antifungal actions of aqueous and ethanolic extracts of the peels of Dioscorea bulbifera and Dioscorea alata were investigated using standard techniques. The aqueous extract of the peel of Dioscorea bulbifera, contained 1.80 ± 0.14% flavonoids, 2.21 ± 0.16% tannins, 0.38 ± 0.04% alkaloids and 3.72 ± 0.03% saponins, whil...

The ameliorating potentials of ginger incorporated feed (10%) on the relative organ weights of Streptozotocin (STZ) induced diabetic rats was investigated. The experiment lasted for three weeks. Results show that administration of 10% ginger feed to the diabetic rats of group 3, resulted in a 29.81% decrease in their resulting hyperglycemia with a...

The ameliorating potentials of cocoyam (Colocasia esculenta L.), ginger (Z.officinale Roscoe) and unripe plantain (Musa paradisiacae L.) incorporated feeds on the relative pancreatic weights of streptozotocin induced diabetic rats was investigated. The blood glucose level of all the rats was measured with a glucometer, the assay of the phytochemica...

The ameliorating potentials of cocoyam (Colocasia esculenta L.), ginger (Z.officinale Roscoe) and unripe plantain (Musa paradisiacae L.) incorporated feeds on the relative pancreatic weights of streptozotocin induced diabetic rats was investigated. The blood glucose level of all the rats was measured with a glucometer, the assay of the phytochemica...

The physicochemical composition, functional properties, inhibitory actions and energy value of the flour of a cream fleshed sweetpotato variety (TIS/87/0087) that is high yielding and commercially sold in South Eastern Nigeria were investigated using standard techniques. The flour was observed to have good functional properties with a pH of 5.32±0....

The polyphenolic composition, oleoresin contents and antioxidant activities of 10 elite accessions of ginger (Zingiber officinale Roscoe) were investigated using standard procedures. The accessions of ginger contained significant quantities of polyphenols and oleoresin which suggested their therapeutic potentials. The antioxidant activities of extr...

Background and Aim: Despite the pharmacological relevance of Water leaf (Talinum triangulare), there is paucity of information in literature on the effect of boiling on its pharmacopotency as well as nutritional properties. Methodology: The total chlorophyll, carotenoids, proximates, phytochemicals, minerals, vitamins and antioxidant assays of the...

Aim: To investigate the ameliorating potentials of cocoyam (Colocasia esculenta L.) and unripe plantain (Musa paradisiaca L.) incorporated feeds on the renal and liver growths of diabetic rats, induced with 55 and 65 mg/kg body weight of Streptozotocin. Method: The blood glucose level of the rats was measured with a glucometer, the protein and g...

The effect of aqueous extract of mistletoe on the blood glucose, electrolytes, transaminases and phosphatase activities of alloxan induced diabetic rats was investigated using their respective kits. Twenty male rats, weighing between 90 and 120 g kg -1 b.wt. were used. Alloxan was injected into the experimental animals at a dosage of 100 mg kg -1 b...

The effect of the colour of five samples of honey (A,B,C,D,E) on their physico-chemical composition, microbial quality and antioxidant activities was studied using standard techniques. The samples had low pH, moderate moisture, ash contents but significant quantities of phenols, flavonoids with higher scavenging activities on 2,2 diphenyl-1-picrylh...

Fifteen turmeric genotypes from the germplasm held at National Root Crops Research Institute Umudike, Nigeria, were evaluated during the season of 2012-2013 at four locations—Jos (8.3833°N, 7.1833°E, 1,200 m a.s.l.), Otobi (7.11667°N and 8.08333°E), Umudike (5.4758°N, 7.5489°E) and Igbariam (6.4°N and 6.93333°E)—in order to select high yielding and...

The physicochemical composition and microbial quality of 7 different water sources (Umudike ukwu bore hole (B5), Umuariaga borehole (B3), Nidoro spring water (S2), Umudike bore hole (B4), Umudike school borehole A (B7), Umudike school bore hole B (B6) and Ahiaeke bore hole (B9) used for root and tuber crop processing in Umudike, Nigeria were invest...

The proximate composition, essential oils and energy value of 10 new varieties of ginger from National Root Crops Research Institute, Umudike, Nigeria were investigated. Results show that all the varieties of ginger analyzed, contained significant quantities of protein, fat and carbohydrates, indicating their nutritive potentials. The significant q...

The extractable sugars and nutritive quality of 10 elite accessions of ginger (Zingiber officinale Roscoe) from National Root Crops Research Institute, Umudike and Nigeria were investigated. The percentage reducing sugar (RS) contents of the ginger accessions were observed to be low and they ranged from 0.28 to 0.65 (%) with UG II 7-24 having the h...

The extractable sugars, moisture contents and microbial quality of 5 honey samples from Umudike farms (Eastern and Western) and different locations in the South Eastern parts of Nigeria (Ahiaeke, Amoaba and Nsukka) were investigated. All the honey samples investigated were observed to contain moderate amounts of reducing sugars (P > 0.05) and non r...

The proximate composition, total carotenoid, reducing sugars and residual cyanide levels of flours of 6 elite yellow and white cassava varieties: UMUCASS 38, UMUCASS 36, UMUCASS 37, TMS0510473, TMS0511636 and TMS9810505 were determined using standard techniques. Results indicated that all the cassava varieties had low moisture contents with TMS9810...

The dry matter, minerals, crude protein, polyphenolic contents and free radical scavenging activities of honey from Umudike farms (Eastern and Western) and different locations in the South Eastern parts of Nigeria (Nsukka, Amoaba and Ahiaeke) were carried out. Results indicate that except the honey from Nsukka, all other samples had high dry matter...

The percentage phytochemical composition of the leaves of pawpaw, bitter kola, tetrapleura, neem and ginger was investigated using the methods of the Association of analytical chemists, Harbone and the Alkaline picrate method. The saponin content of pawpaw, though not significantly different from bitter kola, was the highest among other plants whil...

The phenolic content, antioxidant activity and toxicity of three varieties of extracts of rizga flour on white albino male rats was evaluated. The antioxidant activities of the extracts as determined by the quantities of phenols present and scavenging activities on 2,2-Diphenyl-l-picrylhydrazyl (DPPH) radical indicated that all three varieties of r...

The physico-chemical composition and antioxidant potentials of 6 new varieties of Ginger was evaluated. Analysis of the percentage phenol, oleoresin, lipid, dry matter, crude fibre and ash contents of the ginger varieties using the Association of analytical chemists methods indicated that UGII7GY25 had the highest phenolic content (5.69±0.06) while...

The chemical composition of mistletoe and the effect of its aqueous extract on the protein, lipid metabolism and the antioxidant status of diabetic rats was investigated. Twenty male rats, weighing between 90 and 120 g were used. Alloxan was induced into the experimental animals at a dosage of 100 mg/kg body weight. The rats were divided into 5 gro...

One hundred and ninety pregnant women attending Plateau State Specialist Hospital, Jos, were screened to detect the prevalence of IgM antibodies in their serum using the Biotech Diagnostic Enzyme Linked Immunosorbent Assay Antigen Kit Method. A well-structured questionnaire was administered to the subjects to obtain socio-demographic data. Results...