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17
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Introduction
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September 2009 - June 2012
September 2009 - June 2012
Publications
Publications (17)
This is a protocol for a Cochrane Review (Intervention). The objectives are as follows: To assess the efficacy and safety of Neuroaid for improving recovery after ischaemic stroke. © 2017 The Cochrane Collaboration. Published by John Wiley & Sons, Ltd.
This is a protocol for a Cochrane Review (Intervention). The objectives are as follows: To assess the efficacy and safety of WBV therapy for improving activities of daily living and qualify of life in people with stroke.
Aims:
To assess the effectiveness of edaravone for acute stroke including ischemic stroke and intracerebral hemorrhage (ICH).
Methods:
We identified randomized controlled trials with comprehensive searches and performed systematic reviews according to the Cochrane methods of systematical reviews.
Results:
Edaravone can reduce the rate of death...
This is the protocol for a review and there is no abstract. The objectives are as follows: To assess the efficacy and safety of WBV therapy for improving activities of daily living and qualify of life in people with stroke. © 2013 The Cochrane Collaboration. Published by John Wiley & Sons, Ltd.
Cerebral ischemia, traumatic brain injury, intracerebral hemorrhage and other brain insults trigger neurogenesis in the subventricular zone and hippocampal subgranular zone, and newly formed blood vessels promote the migration of these new neuronal cells to damaged brain regions. The molecular steps involved in brain injury-induced angiogenesis and...
Background and purpose:
FTY720 (fingolimod) is a known sphingosine-1-phosphate (S1P) receptor agonist, which has been used in clinical trials for treating multiple sclerosis, renal transplantation, and decreasing reperfusion injury in heart, liver, and kidney. Most of these clinical trials have showed a positive effect. Especially, the trials of M...
Neural stem cells, which reside mainly in the subventricular and subgranular zones of the hippocampus, can regenerate new neuroblasts after various brain insults. Aided by vascular remodeling, these new neuroblasts migrate long distances to injured brain regions. Studies have suggested that high-mobility group box1 (HMGB1), a nonhistone nuclear DNA...
High-mobility Group Box1 (HMGB1) protein is massively released into the cytoplasm induces inflammation following various insults such as sepsis, acute cerebral ischemia, and pancreatitis. However, whether HMGB1 can act as an early proinflammatory cytokine to promote inflammation after intracerebral hemorrhage (ICH) is unclear. We explored this ques...
Background:
Randomized controlled trials (RCTs) are the most important evidence to guide clinical practice in the treatment of acute stroke. This study aims to evaluate the changes of quantity and methodological quality of acute stroke RCTs in Mainland China published in recent 15 years.
Method:
We included un-confounded RCTs on acute stroke fro...
Background:
The optimal therapy for preventing recurrent stroke in people with cryptogenic stroke and patent foramen ovale (PFO) has not been defined. The choice between medical therapy (antithrombotic treatment with antiplatelet agents or anticoagulants) and transcatheter device closure has been the subject of intense debate over the past several...
The sudden loss of blood supply in ischemic stroke is associated with the increase of calcium ions within neurons. Inhibiting this increase could protect neurons and hence might reduce neurological impairment, disability and handicap after stroke.
To determine whether calcium antagonists reduce the risk of death or dependency after acute ischemic s...
In patients with acute ischemic stroke (AIS), platelets are activated in the acute phase, releasing neurotoxic, and thrombogenic eicosanoids, which may reduce the brain blood flow and cause brain damage. Sodium ozagrel (ozagrel), a thromboxane A2 synthase inhibitor, is one of the most studied drugs which may reduce the risk of neurological impairme...
Objective:
To assess the efficacy and safety of human urinary kallidinogenase injection (HUK) in treating patients with acute ischemic stroke.
Methods:
We searched the Chinese Stroke Trials Register, the Cochrane Stroke Group Trials Register, CENTRAL, Medline, EMBASE, the China Biological Medicine Database(CBM), and the China National Knowledge...
