Aynur sarı

Istanbul University · Department of Pharmacognosy

Background and Aims: Scorzonera ketzkhowelii Sosn. ex Grossh. (Asteraceae) was reported as a new species in the Flora of Turkey in 2010. However, there have been no prior biological or chemical investigations conducted. Methods: This study aims to investigate the antimicrobial activities of the petroleum ether, dichloromethane, ethyl acetate, and...

Leaves of Scorzonera incisa DC. (Asteraceae) are eaten raw against diabetes and headache. Evaluation of medicinal, edible plants using profiling methods has become a common phenomenon. Petroleum ether (PE), ethyl acetate (EA), and n‐butanol (BU) fractions were prepared from ethanol extract of the aerial parts of the plant. Isolation by HPLC and phe...

A phytochemical investigation of the aerial parts of Taraxacum gracilens Dahlst. (Asteraceae) yielded two coumarins (esculetin (1) and cichorin (2)), two flavonoids (luteolin (3) and chrysoeriol (4)) and four phenolic acids (caffeic acid (5), ferulic acid (6), chlorogenic acid (7) and 3,5-dicaffeoylquinic acid (8)). The presence of these compounds...

Petroleum ether (PE), chloroform (CH), ethyl acetate (EA) and n-butanol (BU) fractions were obtained from ethanol extracts of the roots (SPR) and the above ground (SPH) parts of S. pygmaea. PE fractions were evaluated by GC-MS for profiling the terpenoids and the fatty acids of the plant. 29 compounds in total including saturated (major palmitic ac...

Ethnobotanical and ethnomedicinal studies have become increasingly recognised as a valuable source of information on the use and possible pharmacological activity of many plant species. There is no study presenting traditional herbal remedies used for kidney diseases in Turkey. The purpose of the paper is to compile herbal remedies used in kidney d...

More than 50 species of the genus Scorzonera L. grow naturally in Turkey. Members of this genus, belonging to the Asteraceae family, are used both as food and folk medicine in many regions of the world. In this study, anti-Alzheimer activity of Scorzonera pygmaea Sibth. & Sm., one of Turkey's endemic plant, has been subjected. Ethanol extract from...

Boils are a painful inflammatory skin disease, often accompanied by swelling and redness of the hair follicle and its surroundings by Staphylococcus aureus bacteria. Antimicrobial agents are used in its clinical treatment. In addition to clinical treatment, the treatment applications with herbs continue among the public. In this study, which was pr...

The genus Taraxacum Wigg. is a member of the family Asteraceae. This genus is represented by about 49 species in Turkey. Taraxacum species are commonly used as a diuretic and for the treatment of various diseases such as dyspepsia, reflux, spleen and liver disorders, and anorexia. Compounds from the group of sesquiterpene lactones, triterpenes, phy...

Plants of the genus Taraxacum Wigg., have long been used as medicinal herbs. A phytochemical investigation of the aerial parts of Taraxacum bessarabicum (Hornem.) Hand.-Mazz. subsp. bessarabicum (Hornem.) Hand.-Mazz. (Asteraceae) yielded two coumarins [esculetin (1), cichoriin (2)], three flavonoids [ luteolin (3), luteolin 7-O-β-D-glucoside (4), g...

Scorzonera L. (Asteraceae) species are widespread and utilised as traditional medicine and edible plant. A phytochemical study on ethyl acetate fraction obtained from the ethanol extract of Scorzonera hieraciifolia Hayek (an endemic species of Turkey) roots resulted in isolation of nine compounds; 5-O-feruloyl quinic acid methyl ester (1), 1,5-di-O...

Turkey is one of the richest countries in terms of flora in the world with its extraordinary plant diversity. Its flora consists of about 10000 vascular plants and approximately one third of them (34.4 %) is endemic to the country. In recent years, the use of ethnobotanical information obtained from medicinal plant research has gained attention all...

Phytochemical composition of ethyl acetate fraction and total phenolic content, in vitro antioxidant, anti-inflammatory, antimicrobial activities of petroleum ether, chloroform, ethyl acetate and n-butanol fractions of the ethanol extract obtained from the subaerial parts of Scorzonera pygmaea Sibth. & Sm. (Asteraceae) were investigated. Nine compo...

Due to its geographic location, variable climate and traditional culture, Turkey has a rich flora and the use of plants in folk medicine is very favorable. That practice and knowledge have been passed down from generation to generation. Ethnobotanical surveys are carried out to record traditional treatment methods of plants. In this study, which wa...

In this study, antioxidant, antiacetylcholinesterase, anti-inflammatory, and DNA protecting activities of the aerial parts of Glaucium grandiflorum var. grandiflorum were evaluated. The lyophilized methanolic extract of the aerial parts of G. grandiflorum var. grandiflorum was investigated for potential in-vitro antioxidant properties in thiobarbit...

The genus Scorzonera (Asteraceae) has several species which are used as a vegetable and in folk medicine all around the world. A phytochemical study was carried out on petroleum ether fraction of methanol extract obtained from the roots of Scorzonera veratrifolia Fenzl (Bitlis / Turkey) to investigate the terpenoid composition of the plant. Column...

The Scorzonera genus (Asteraceae) is represented by around 160 species in the world. There are 52 species in Turkey and 31 of them are endemic. Scorzonera species’ roots and fresh shoots are consumed raw or cooked as vegetable and used in traditional medicine as analgesic, antirheumatic, anthelmintic, diuretic, wound healer, in the treatment of inf...

Dünya üzerinde, Scorzonera L. cinsi (Asteraceae familyası), yaklaşık 160 tür ile temsil edilmektedir. Türkiye’de ise 31 tanesi endemik olmak üzere 52 tür bulunmaktadır. Bu cinsin bazı türlerinin kök ve taze sürgünleri, çiğ veya pişmiş halde sebze olarak tüketilmektedir. Scorzonera L. türleri, halk arasında, analjezik, antiromatizmal, antihelmentik,...

Asteraceae familyasına ait, Scorzonera L. cinsi, Avrupa, Asya ve Kuzey Afrika bölgelerinde yayılmış olarak yaklaşık 160 tür ile temsil edilmektedir. Türkiye ise bünyesinde barındırdığı 31 adeti endemik olmak üzere toplam 52 türü ile bu cins açısından zengin çeşitlilik sunmaktadır. Bu cinsin bazı türlerinin kültürü yapılarak kök ve toprak üstü kısım...

Glaucium grandiflorum Boiss. et Huet. (Papaveraceae) türü Orta Doğu’nun Doğu Akdeniz’den İran’a kadar uzanan değişik bölgelerinde yetişen çok yıllık otsu bir bitkidir. Flora of Turkey’de, G. grandiflorum türünün iki varyetesi bildirilmiştir; var. grandiflorum ve var. torquatum, bunlardan sonuncusu Türkiye için endemiktir. Glaucium türleri halk aras...

A new 3-benzylphthalide, scorzoveratrin 4'-O-β-glucoside (1), together with the known 3-benzylphthalides, scorzoveratrin (2) and scorzoveratrozit (3), the caffeoyl derivatives, chlorogenic acid methyl ester (4), 4,5-dicaffeoylquinic acid (5), 4,5-dicaffeoylquinic acid methyl ester (6), 3,5-dicaffeoylquinic acid (7) and caffeic acid (8) were isolate...

A phytochemical investigation of Scorzonera veratrifolia Fenzl (Asteraceae) yielded two new 3-benzylphthalides, scorzoveratrin (1) and scorzoveratrozit (2), together with five known compounds, chlorogenic acid (3), chlorogenic acid methyl ester (4), cryptochlorogenic acid (5), 4,5-dicaffeoylquinic acid (6) and 3,5-dicaffeoylquinic acid (7). All sec...

The antimicrobial activities of the ethanolic extracts and petroleum ether, ethyl acetate and n-butanol tractions obtained from the subaerial parts of two Scorzonera species (5. latifolia and 5. veratrifolia) (Asteraceae) have been tested against Staphylococcus aureus ATCC 6538, Staphylococcus epidermidis ATCC 12228, Escherichia coli ATCC 8739, Kle...

From the subaerial parts of S. tomentosa L. (Asteraceae), two new dihydroisocoumarins, compounds 1 and 2, a new phthalide, 3, and a new stilbene derivative, 4, were isolated, together with four known compounds, (±)-hydrangenol (5), (−)-hydrangenol 4′-O-β-glucoside (6), (±)-hydramacrophyllol A (7), and (±)-hydramacrophyllol B (8). All secondary meta...

Alkaloidal extracts of the aerial parts of the samples of Glaucium grandiflorum Boiss. et Huet var. grandiflorum collected from three different parts of Turkey and their major alkaloids allocryptopine, protopine, (+)-isocorydine, (+)-corydine were screened for their cytotoxicity using brine shrimp lethality test. All the samples of Glaucium grandif...

From the aerial parts of Papaver triniifolium Boiss. (Papaveraceae) collected from Erzincan (Eastern Anatolia), two new benzylisoquinoline alkaloids, miltanthoridine and miltanthoridinone were isolated. Their structures were established through the use of UV, EIMS, and NMR techniques.

The two main quaternary alkaloids of Papaver cylindricum are the new phthalideisoquinoline (+)-N-methyl-α-narcotine [1] and the known (-)-N-methylthebaine. Papaver pseudo-orientale provided (-)-α-N-methopapaverberbine [2], isolated as the iodide, which is the first N-methoprotoberberine salt hydroxylated at C-13, as well as the bicyclic cotarnine [...

A new dehydroaporphine alkaloid (-)-6a,7-dehydrofloripavidine has been isolated from the aerial parts of Papaver fugax Poir. (Papaveraceae) collected from Erzurum (Eastern Anatolia). (-)-Floripavidine (aporphine) and (-)-mecambrine (proaporphine) were isolated as major alkaloids. Other bases present were (+)-salutaridine (promorphinane) and argenti...

The constituents of Glaucium grandiflorum var. grandiflorum collected from Doruksaray (Erzincan) have been investigated and the major alkaloids of the aerial parts were identified to be allocryptopine and protopine. In addition (-)-α-N-methylcanadine, (-)-β-N-methylcanadine, (+)-reticuline and berbithine have been isolated as minor alkaloids. The o...

New alkaloids, (+)-triniifoline, (+)-O-ethyltriniifoline (rhoeadine type), and (+)-miltanthaline (benzylisoquinoline type) have been isolated from aerial parts of Papaver triniifolium Boiss, (Papaveraceae). The major alkaloids were medicinally important (-)-alpha-narcotine and papaverine together with (-)-mecambrine in the species whereas narceine...