Aron D Rose

Yale University | YU · Department of Ophthalmology and Visual Sciences

I stifle a gasp as the young woman lifts her blouse. There, her baby son struggles to suckle, his access to the breast nearly obstructed by a hideously engorged, phallus-like tumor that grows out of his eye socket. She looks at me, her only hope, with unbearable shame. Treating patients at this Buddhist monastery–run hospital in central Myanmar is...

Performing surgery in the developing world presents unique challenges and dilemmas for the visiting physician from an industrialized country. Language barriers, widespread, profound pathology, and lack of adequate facilities are obvious hurdles. A more subtle problem, though every bit as significant, is that the principles and procedures we routine...

To assess intraoperative thermal levels at the wound site during divide-and-conquer phacoemulsification with the Sovereign with WhiteStar (SWS) system or the Legacy with AdvanTec and NeoSoniX (LAD) system. Prospective, randomized, parallel-group, comparative study. Twenty-six subjects from a private clinical practice underwent divide-and-conquer ph...

To compare the postoperative outcomes of cataract surgery performed with the Sovereign 4.0 system or the Sovereign system with WhiteStar power modulation. Ambulatory surgery centers at 4 sites in the United States. This was a 3-month, open-label, randomized, parallel-group comparative clinical trial in patients with visually interfering cataract. S...

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Acute lymphocytic leukemia can be associated with an occlusive microvascular retinopathy. There is a potential for worsening of this occlusive microvascular retinopathy by radiation damage to the retinal vasculature (radiation retinopathy) and by the toxic effects of chemotherapy. An 18-year-old woman with T-cell acute lymphocytic leukemia received...

In a three-month, double-masked, randomized clinical trial, we evaluated the once-daily ocular hypotensive efficacy of 0.25% levobunolol and 0.25% timolol in 80 patients with open-angle glaucoma or ocular hypertension. Thirty-seven of the 39 patients (95%) in the 0.25% levobunolol group and 35 of the 41 patients (85%) in the 0.25% timolol group suc...

Glaucoma was induced in cynomolgus monkeys by photocoagulating the trabecular meshwork with the argon laser. Repeat treatments were often necessary and wide intraocular pressure fluctuations were characteristic. Baseline intraocular pressure was measured with a calibrated pneumatonometer hourly for six hours. On a succeeding day a baseline measurem...