Archana Keche

All India Institute of Medical Sciences, Raipur · MICROBIOLOGY

Invasive Aspergillosis (IA) is a severe and fatal infection, especially in immunocompromised patients. Galactomannan is a polysaccharide antigen present in the cell wall of Aspergillus species, which is secreted into the blood and other body fluids during hyphal growth. Therefore, detecting galactomannan antigen is very useful in diagnosing IA, alo...

Knowing the spectrum, prevalence, and modes of diagnosis of pulmonary aspergillosis (PA) will be beneficial to clinicians for its early diagnosis and management. This study aims to estimate the prevalence, spectrum, and role of serological tests and radiological findings in the diagnosis of PA. A total of 150 patients were suspected of having PA af...

Primary cutaneous blastomycosis is very rare in non-endemic regions like India. Only few cases have been reported from India. Herein, we are reporting a rare case of chronic cutaneous blastomycosis in a young immunocompetent male presenting as mycetoma with multiple discharging sinuses in the anterior abdominal wall with no significant travel histo...

Background Sudden upsurge in cases of COVID-19 Associated Mucormycosis (CAM) following the second wave of the COVID-19 pandemic was recorded in India. This study describes the clinical characteristics, management and outcomes of CAM cases, and factors associated with mortality. Methods Microbiologically confirmed CAM cases were enrolled from April...

Keratomycosis is common in Indian subcontinent. Diagnosis of the causal agent and successful management is a challenge for the clinician. Scedosporium is a rare fungus species, and it is relatively rare in causing keratomycosis. We report the case of a 29-year-old male who presented with complaints of redness, watering, and white lesion over his le...

Background Candida parapsilosis infection has recently emerged as an important antifungal-resistant nosocomial pathogen having the unique ability to grow on inanimate objects and surfaces. The aim of this study was to analyze the predisposing conditions, outcome, and antifungal susceptibility pattern of candidemia due to C. parapsilsosis complex....

Lophomonas infection is an emerging parasitic disease-causing respiratory infection. Although common in immunocompromised patient, it has been observed also in some immunocompetent cases. We report the case of a 45-year-old male who presented with productive cough, fever, and chest pain, with marked eosinophilia and cavitary lesion in the X-ray che...

Background Increased occurrence of mucormycosis during the second wave of COVID-19 pandemic in early 2021 in India prompted us to undertake a multi-site case–control investigation. The objectives were to examine the monthly trend of COVID-19 Associated Mucormycosis (CAM) cases among in-patients and to identify factors associated with development of...

A case of Acanthamoeba rhinorrhea in a 32 years female, who was recently recovered from COVID-19 infectionat a tertiary care institute in India. Though, there was no standard treatment protocol for management of amoebic-meningo encephalitis. The patient was managed successfully with combination therapy of amphotericin B and miltefosine. Agents havi...

Poster session 3, September 23, 2022, 12:30 PM - 1:30 PM Objectives To study the Candida pelliculosa isolates, from the blood culture of neonates admitted to district hospital SNCUs in the state of Chhattisgarh, their antifungal susceptibility pattern, risk factors, and clinical co-relation. Although Candida species remain the leading cause of inv...

Poster session 1, September 21, 2022, 12:30 PM - 1:30 PM Objectives 1. To isolate and identify various species of Dermatophytes from clinical specimens 2. To perform and analyze the antifungal susceptibility testing of isolated Dermatophytes for commonly used antifungal agents; terbinafine and itraconazole. Methods A prospective study was conduct...

Poster session 2, September 22, 2022, 12:30 PM - 1:30 PM Objective To assess the burden of fungal etiology of clinically suspected mycotic keratitis amongst the patient presented to the Ophthalmology department in a tertiary care hospital in Chhattisgarh. Methods This is a laboratory-based retrospective study of the corneal scrapings received for...

Poster session 2, September 22, 2022, 12:30 PM - 1:30 PM Objectives Candida parapsilosis infection has recently emerged as an important antifungal-resistant nosocomial pathogen having the unique ability to grow on inanimate objects and surfaces. Very limited studies from low and middle-income countries are available on the association of risk fact...

Poster session 3, September 23, 2022, 12:30 PM - 1:30 PM Introduction: A rare finding of abdominal wall clinical presentation of persistent progressive tumefaction with draining sinus with no granules caused by Nocardia brasiliensis. Methods History: A 22-year-old presented to the Dermatology OPD with complaints of swelling and tenderness and disc...

Poster session 2, September 22, 2022, 12:30 PM - 1:30 PM Aims and Objective To identify the causative agents of suspected subcutaneous mycosis patients attending to a tertiary care hospital, Chhattisgarh, India. Introduction Subcutaneous mycoses are a group of fungal infections of dermis and subcutaneous tissue caused by both melanized and hyalin...

Various kinds of fungal agents have been observed in the environment. Fungi can enter the human body by penetration following trauma and are responsible for various types of subcutaneous mycotic lesions. In this case report, we present the case of a 47-year-old female patient who presented with swelling on the lateral aspect of the left lower leg a...

Background: Increased occurrence of mucormycosis in India during the second wave of the COVID-19 pandemic in early 2021 in India subsequently prompted us to undertake a multi-site case-control investigation. The objectives were to examine the monthly trend of Covid-19 Associated Mucormycosis (CAM) cases among in-patients and to identify factors ass...

Objective: To describe the clinical pattern of invasive fungal sinusitis in COVID-19 and post-COVID-19 cases. Methods: All patients affected by COVID-19 or having a history of COVID-19 infection with an invasive fungal lesion (mucormycosis/aspergillosis) of the paranasal sinuses, orbit, palate, brain, lung, skin/cheek, and dental has been evalua...

The study aimed to determine clinical presentation, contributing factors, medical and surgical management, and outcome of patients with coronavirus disease 2019 (COVID-19)-associated mucormycosis (CAM). A cross-sectional, single-center study was conducted on patients receiving multidisciplinary treatment for mucormycosis following the second wave o...

A fifty-nine-year-old female with corneal ulcer with a history of trauma in the past having clinical presentation of fungal keratitis visited the Ophthalmology outpatient department with a history of redness, watering, pain and white discoloration of the right eye cornea for two months. Sample was cultured on non-nutrient agar medium and revealed A...

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Parasitic infections do not usually present with rapidly progressive renal failure but can provoke glomerular lesions which are mostly proliferative. In filarial infection, glomerular involvement is usually mild and transient, and presentation with renal failure is rare. We report occult filariasis presenting as rapidly progressive renal failure du...

Background An appropriate specimen is of paramount importance in Real Time reverse transcription-polymerase chain reaction (rRT-PCR) based diagnosis of novel coronavirus (nCoV) disease (COVID-19). Thus, it’s pertinent to evaluate various diversified clinical specimens’ diagnostic utility in both diagnosis and follow-up of COVID-19. Methods A total...

Keratitis is a very serious clinical condition caused by bacteria, fungi or parasites. It is associated with serious complications like blindness or endophthalmitis if remained undiagnosed. A 42-year-old male patient with the history of foreign body inoculation presented with mild pain and redness. After clinical examination, fungal keratitis was d...

Mycetoma is disorder of subcutaneous tissue, skin, and bones, mainly the feet. Etiologically divided in Eumycetoma and actinomycetoma, since the treatment of both is different, the diagnosis is mandatory. This is the case of 35-year-old lady with swelling in left foot with multiple discharging sinuses for 5 years that was none responding to antifun...

Rhinoentomophthoromycosis due to Conidiobolus coronatus is a rare, chronic, granulomatous disease, occurring mainly in tropical countries including India. We report two cases of rhinoentomophthoromycosis in an 18-year-old female and a farmer of 35 years residents of Chhattisgarh shifted from Madhya Pradesh and Orrisa. It was diagnosed by microscopy...

BACKGROUND: Enteric fever is the most common cause of community acquired blood stream infections in under developed and developing countries. The enteric fever is exclusive to humans and transmitted through the faeco-oral route. Though India is an endemic zone for enteric fever, the data is very scarce from Central India. The present study was unde...

Background: Surgical site infections are associated with prolonged hospital stays and increased cost of therapy. Prophylactic use of antimicrobials is to prevent the incidence of postoperative wound infection. To generate data on postoperative use of antimicrobials this study was planned.Methods: The information was collected in semi-structured que...

Wound infection can be caused by variety of organisms like bacteria, virus, fungi and protozoa and may co-exist as poly microbial communities. Even though the bacterial profile of pus samples in many studies remain the same, the antibiotic resistance pattern of these isolates has shown a lot of variations. This study was conducted in the department...

Background: Staphylococcus aureus is a pathogen causing wide spectrum of infections. It has tendency for the development of multidrug resistance thereby exposing the selection of appropriate treatment. Therefore, the present study was undertaken to find out the antibiotic susceptibility pattern of Staphylococcus aureus isolated from various clinica...

Acanthamoeba species cause granulomatous Acanthamoeba encephalitis in immunocompromised patients. We report a case of acute purulent meningoencephalitis with a focal neurological deficit caused by Acanthamoeba species in a 2 years immunocompetent child.

Non-tubercular mycobacterial infections (NTM-Non-tubercular mycobacterial infections) are becoming increasingly common. Mycobacterium abscessus is a rare cause of human infection and is difficult to diagnose unless suspected for the same. A 31-year-old patient, diagnosed to have right breast abscess associated with axillary lyphadenopathy with feve...

Background: Onychomycosis is commonly caused by dermatophytic group of fungi. Non dermatophytic group of fungi are rarely isolated from nail Onychomycosis due to non dermatophytic molds Cladosporium spp. Aim of the study was to isolate and identify fungal agents from nail clipping of patient clinically having onycomycoses. Methods: Clinical sample...

Objectives: Urinary Tract Infections (UTIs) are the most common serious bacterial infections which are seen during infancy. The aim of the present study was to evaluate aetiology, and antimicrobial resistance patterns among infants and children who approached our hospital for treatment of UTIs. Methods: In this observational study which was carr...

Seventeen year young male patient presented with complain of burning micturation, fever since 8 days and ulcer in genital area. After clinical examination impression smear and swab from ulcer were received. Gram stain showed presence of pus cells, gram negative plump coccobacilli. Even though primary isolation of Haemophilus ducreyi is difficult we...

A 4-year-old young male child was investigated for spinal tuberculosis (TB) and Mycobacterium tuberculosis was isolated from the sample. In another case, a 2-year-old male patient with Potts spine, M. tuberculosis was isolated from the pus sample. In both cases, Bacillus Calmette-Guιrin (BCG) scar was absent. BCG vaccination may prevent bone TB.

HIV constitutes major health problem worldwide. Indicator diseases will help in early diagnosis & management of HIV. Cutaneous diseases are common in patients infected with HIV. In many patients skin is the only organ affected throughout the course of disease. The aim of this study is to estimate the prevalence of different skin diseases in HIV inf...

We report a case of a 26-year-old female patient diagnosed with chronic otomastoiditis caused due to Mycobacterium fortuitum. Definitive identification of pathogen was done on the basis of growth characteristics and biochemical reaction. M. fortuitum was isolated from the lesion. M. fortuitum is a rarely reported cause of otitis media and mastoidit...

This study was carried out in Indira Gandhi Government Medical College Nagpur to find out different marketing strategies used by pharmaceutical companies to influence to change the prescription of drug by doctors. Study was carried out with the help of structured questionnaire. The prescribing doctors and medical representatives were study particip...