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Recovery and Prediction of Physical Functioning Outcomes During the First Year After Total Hip Arthroplasty

Authors:
  • Bærum Hospital Vestre Viken Hospital Trust and OSLO and Akershus University College (HiOA)

Abstract and Figures

Objectives: To investigate recovery of physical functioning in patients during the first year after total hip arthroplasty (THA), and to predict postoperative walking distance outcomes from preoperative measures. Design: A longitudinal prospective design was used. Data were analyzed by repeated-measures analysis of variance and multivariate regression analyses. Setting: Two hospitals. Participants: Patients with hip osteoarthritis were consecutively included and assessed preoperatively (n=88), at 3 months (n=88), and at 12 months (n=64) after THA. Interventions: Not applicable. Main outcome measures: Physical functioning was assessed by objective measures-the 6-minute walk test (6MWT), stair climbing test, Index of Muscle Function, figure-of-eight, and active hip range of motion-and the subjective measures by Harris Hip Score and Hip dysfunction and Osteoarthritis Outcome Score. Results: In objective measures, improvements were found from preoperatively to 3 months in 6MWT (P<.01) and stair climbing test (P<.05) scores, while all measures had improved from 3 to 12 months (P≤.001). In contrast, all the subjective measures showed substantial improvements at 3 months, but small further improvements from 3 to 12 months (P<.001). Age, sex, preoperative 6MWT distance, and hip range of motion predicted 6MWT outcomes at 3 and 12 months (P≤.01). Conclusions: The objective measures of physical functioning improved gradually during the first postoperative year, while the subjective measures showed large early improvements, but little further improvements. Younger age, male sex, and better scores of walking distance and hip flexibility before surgery predicted better score in walking distance at both 3 and 12 months after surgery.
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ORIGINAL ARTICLE
Recovery and Prediction of Physical Functioning Outcomes
During the First Year After Total Hip Arthroplasty
Kristi Elisabeth Heiberg, MSc,
a,b
Arne Ekeland, PhD,
c
Vigdis Bruun-Olsen, MSc,
b
Anne Marit Mengshoel, PhD
b
From the
a
Department of Physiotherapy, Bærum Hospital, Vestre Viken Hospital Trust, Sandvika;
b
Department of Health Sciences, Institute of
Health and Society, University of Oslo, Oslo; and
c
Martina Hansen’s Hospital, Sandvika, Norway.
Abstract
Objectives: To investigate recovery of physical functioning in patients during the first year after total hip arthroplasty (THA), and to predict
postoperative walking distance outcomes from preoperative measures.
Design: A longitudinal prospective design was used. Data were analyzed by repeated-measures analysis of variance and multivariate regression
analyses.
Setting: Two hospitals.
Participants: Patients with hip osteoarthritis were consecutively included and assessed preoperatively (nZ88), at 3 months (nZ88), and at
12 months (nZ64) after THA.
Interventions: Not applicable.
Main Outcome Measures: Physical functioning was assessed by objective measuresdthe 6-minute walk test (6MWT), stair climbing test, Index
of Muscle Function, figure-of-eight, and active hip range of motiondand the subjective measures by Harris Hip Score and Hip dysfunction and
Osteoarthritis Outcome Score.
Results: In objective measures, improvements were found from preoperatively to 3 months in 6MWT (P<.01) and stair climbing test (P<.05)
scores, while all measures had improved from 3 to 12 months (P.001). In contrast, all the subjective measures showed substantial
improvements at 3 months, but small further improvements from 3 to 12 months (P<.001). Age, sex, preoperative 6MWT distance, and hip
range of motion predicted 6MWT outcomes at 3 and 12 months (P.01).
Conclusions: The objective measures of physical functioning improved gradually during the first postoperative year, while the subjective
measures showed large early improvements, but little further improvements. Younger age, male sex, and better scores of walking distance and hip
flexibility before surgery predicted better score in walking distance at both 3 and 12 months after surgery.
Archives of Physical Medicine and Rehabilitation 2013;94:1352-9
ª2013 by the American Congress of Rehabilitation Medicine
Patients with hip osteoarthritis (OA) suffer from pain and disabil-
ities. When conservative treatment no longer is effective, total hip
arthroplasty (THA) is the treatment of choice. During the last couple
of decades, the evaluation of outcomes after THA has shifted from
focusing on success or failure of the implant to evaluate pain relief,
improvements in physical functioning, and quality of life.
1,2
A systematic review showed that patients with THA may exper-
ience considerable pain relief already a few days after surgery,
3,4
and
after 3 months pain intensity measures were reduced by approxi-
mately 60%.
5
Recovery of physical functioning has been evaluated
by objective measur es of performance, such a s walking distance,
6
and
by subjective measures, such as the Western Ontario and McMaster
Universities Osteoarthritis Index.
2,7
Compared with preoperative
scores, a deterioration in objective measures of walking distance
within the first postoperative weeks, small improvement at 3 months,
and further gradual increase to 12 months postoperatively have been
reported.
8-11
A different pattern has been revealed when the recovery
of physical functioning was assessed by subjective measures.
Approximately 50% improvement in Western Ontario and McMaster
Universities Osteoarthritis Index physical functioning score was
Supported by the South-Eastern Norway Regional Health Authority.
No commercial party having a direct financial interest in the results of the research supporting
this article has or will confer a benefit on the authors or on any organization with which the authors
are associated.
0003-9993/13/$36 - see front matter ª2013 by the American Congress of Rehabilitation Medicine
http://dx.doi.org/10.1016/j.apmr.2013.01.017
Archives of Physical Medicine and Rehabilitation
journal homepage: www.archives-pmr.org
Archives of Physical Medicine and Rehabilitation 2013;94:1352-9
reported from preoperatively to 3 months postoperatively,
5,10
with
further small improvements found at6 and 12 months.
5,11,12
Thus, the
pattern of recovery seems to be different depending on whether it is
evaluated by objective or subjective measures.
Studies examining the recovery of physical functioning after
THA have mostly applied either subjective or objective measures.
13
Two studies applied both subjective and objective measures to assess
the outcomes at least twice.
14,15
In these studies, most of the
improvementsin both objective measures and subjective measures of
physical functioning occurred within the first 3 months and only
small further improvements were found thereafter. These results are
in contrast to the aforementioned studies. Thus, it cannot be
concluded what to expect with regard to the course of recovery of
physical functioning.To address this issue further, our patient sample
was assessed by both subjective and objective measures of physical
functioning preoperatively and during the first year after THA.
For patients and health professionals to give realistic expec-
tations and set attainable therapeutic goals, it is important to know
whether the patients’ preoperative physical functioning is of any
significance to how their physical functioning will become post-
operatively. Prior studies have shown that advanced age, female
sex, multiple comorbidities, low patient expectations, high levels
of preoperative pain, and poor preoperative self-reported physical
functioning scores predict worse postoperative self-reported
physical functioning after THA.
16-20
Many patients desire to
improve their walking ability after surgery, and walking ability is
an important factor for living an active life and being independent
in daily activities.
21
We have, however, not found any studies
predicting the outcome in an objective measure of walking
distance after THA. Presently, we assumed that a patient’s walking
ability before surgery was related to the outcome in walking
ability after surgery. Furthermore, patients applying for THA have
often impaired hip flexibility and balance, which we think may
influence walking ability. We also presumed that patients who lead
a physically active life before surgery may achieve a good result
from surgery. Thus, these variables were entered as plausible
predictive factors in a regression model together with age, sex, and
preoperative pain severity.
The aims of this study of patients with THA were as follows:
first, to examine the changes in physical functioning assessed
before surgery and at 3 and 12 months after surgery by objective
and subjective measures, and second, to examine which preoper-
ative measures of physical functioning could predict walking
distance outcomes at 3 and 12 months after THA.
Methods
Study design, participants, and ethics
This article reports analysis of longitudinal data collected preopera-
tively and at 3 and 12 months after THA. The 12-month data were also
applied to evaluate the long-term effects of an exerciseprogra m.
22
This
exercise program showed a minor effect on walking after 1 year. Thus,
we have controlled for the exercise group in the statistical analysis.
Patients approved for primary THA were recruited from 2
hospitals in the Oslo area. They were enrolled from October 2008
to June 2010. Inclusion criteria were diagnosis of hip OA and
residence within a radius of approximately 30 kilometers to the
hospital, so that attending an exercise program after surgery could
be possible. The exclusion criteria were OA in a knee or contra-
lateral hip that restricted walking, as well as neurologic disease,
heart disease, dementia, drug abuse, or inadequate ability to read
and understand Norwegian. The study was approved by The
Regional Committee for Medical Research Ethics and the
Norwegian Social Science Data Services.
Patient characteristics
Before surgery, the patients completed a questionnaire including
items on age, sex, body height and weight, educational level,
marital status, and comorbidities.
Objective measures
6-minute walk test
The 6-minute walk test (6MWT) is a measure of walking ability. It
measures the distance in meters walked indoors at a comfortable
speed within 6 minutes.
23
The patients walked back and forth
along a 40-meter corridor. A clinically relevant improvement is
50 meters.
24
The 6MWT is considered to be an adequate measure
of physical functioning in subjects with OA and THA
11,25
and is
found to be reliable and valid.
26
Stair climbing test
The stair climbing test (SCT) also assesses walking ability. The
patients ascended and descended 8 steps, each 16 centimeters
high, as fast as they could without running. They used alternate
legs and were allowed to support themselves by holding onto the
stair rail. The time was measured in seconds.
Figure-of-eight test
The figure-of-eight test is a measure of balance. The patient walks
within a double set of circles. The outer circles are 180 centi-
meters in diameter, and the inner circles are 150 centimeters in
diameter. There is a 15-centimeter space between the lines in
which the feet must be placed during walking. Every step on and
outside the lines was registered, and the higher the number the
worse the score. The figure-of-eight test is reported to be reliable
and valid.
27
Index of Muscle Function
Index of Muscle Function (IMF) consists of tests of general
mobility, muscle strength, balance/coordination, and endurance.
The assessor evaluated the patient’s performance on a 3-point
scale (range, 0e2).
28
The total score ranges from 0 (best) to
40 (worst). The IMF is considered to be a valid and reliable
measurement tool for patients with OA.
28,29
Active hip range of motion
The degree of active hip range of motion (ROM) in flexion and
extension was measured by a goniometer,
30
summarized and
reported as the total score for active hip ROM.
List of abbreviations:
HOOS Hip dysfunction and Osteoarthritis Outcome Score
IMF Index of Muscle Function
OA osteoarthritis
ROM range of motion
SCT stair climbing test
THA total hip arthroplasty
6MWT 6-minute walk test
Recovery and prediction after total hip arthroplasty 1353
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Subjective measures
Harris Hip Score
The Harris Hip Score is a disease-specific measure of hip disabil-
ities. The topics included are pain, functions of daily living, and
gait.
31
The rating scale is from 0 (worst) to 100 points (best). The
Harris Hip Score is considered to have good validityand reliability.
32
Hip dysfunction and Osteoarthritis Outcome Score, version
LK 2.0
This disease-specific questionnaire consists of 5 subscales: pain,
other symptoms, activities of daily living, functions of sport and
recreation, and hip-related quality of life. The scores reach from
0 (worst) to 100 points (best). A change of more than 8 to 10
points in the Hip dysfunction and Osteoarthritis Outcome Score
(HOOS) is considered to be clinically relevant.
33
We translated the
Swedish HOOS 2.0 version into Norwegian using standard
procedures.
34
The Swedish questionnaire has been found to be
valid and responsive to changes.
35
Norway and Sweden are
culturally close. Therefore, the psychometric properties of the
Norwegian version were not tested.
Surgery and physiotherapy
Cemented hip prostheses by either Exeter
a
or Spectron
b
were used,
both with a posterolateral approach.
36
All the patients received
daily routine physiotherapy care while hospitalized,
37
and
69 patients (78%) continued with physiotherapy after discharge.
From 3 to 5 months postoperatively, approximately half of the
patients participated in an exercise program.
Statistical analysis
Descriptive data are presented as mean and its 95% confidence
interval or in number and percentage. The continuous data were
mainly normally distributed. The data analyses were conducted
with and without the outlier shown in figures 1 and 2, but the
outlier did not change our results. Changes in physical functioning
and symptoms over time were analyzed by repeated-measures
analysis of variance, with participation in an exercise program
(yes/no) included as a covariate. If Mauchley’s test of sphericity
was violated, we applied a Greenhouse-Geisser correction. Post
hoc tests were run with Bonferroni corrections.
The differences between men and women were analyzed by
independent sample ttests. The associations between the different
candidate predictors and between the predictors and the outcome
variables were analyzed by the Pearson’s correlation analysis.
Candidate predictors for the regression analysis were sex and the
variables that showed significant correlations (P.05) in the
bivariate analysis to the outcomes in the 6MWT at 3 and
12 months. When predicting the outcome in the 6MWT at 12
months, it was controlled for whether the patients had participated
in an exercise program or not.
38
If the correlation coefficient
between the independent variables was more than 0.7, they were
assumed to measure the same dimensions, and only the one with
the highest correlation coefficient with the dependent variable was
entered into the regression analysis.
39
The variables that fulfilled the correlation criteria were
included in the multiple regression analysis. The predictors with
the smallest contribution to explain the variance of the dependent
variable were excluded from the model by manual backward
stepwise procedure. Thereby, the best subsets of statistically
significant predictors were selected. For a final check of the
variables’ contribution within the model, the variables removed
from the models were individually re-entered. The scatter plots of
the distribution of the residuals for the models were acceptable.
The regression coefficients are reported with 95% confidence
interval. Pvalues of .05 or less were considered statisti-
cally significant.
Fig 1 Relation between the patients’ preoperative walking distance
in the 6MWT and change in walking distance from preoperatively to
3 months after THA (nZ88).
Fig 2 Relation between the patients’ preoperative walking distance
in the 6MWT and change in walking distance from preoperatively to
12 months after THA (nZ64).
1354 K.E. Heiberg et al
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Results
Patients
Before surgery 139 eligible patients were asked to participate.
Thirty-six patients declined, leaving 103 patients to be assessed
preoperatively. Fifteen patients withdrew from the study during
the first 3 months. They were mostly women and clinically worse
than those included in the study in preoperative measures of
6MWT, SCT, IMF, Harris Hip Score, and HOOS pain and activ-
ities of daily living (P<.05). Thus, 88 patients constitute the data
material preoperatively and at 3 months. Twenty-four patients
withdrew from the 12-month assessments. They did not differ at
preoperative- or 3-month assessments from the 64. At 12 months,
64 patients were left to be analyzed. The patient characteristics of
those participating in the study are presented in table 1.
Recovery of physical functioning
Recovery of physical functioning and symptoms from before
surgery and throughout the first year after surgery are presented in
table 2. The 6MWT distance improved by a mean of 9% and the
SCT score by 7% from preoperatively to 3 months postoperatively
(P<.05), and further improvements of 17% and 15% were found
from 3 to 12 months (P<.001). In the other objective measures, no
early improvement was shown at 3 months (P>.05), but from 3 to
12 months, figure-of-eight test score improved in mean by 30%,
IMF by 33%, and hip ROM by 12% (P.001). No statistically
significant difference in 6MWT outcome at 12 months was found
between those participating and those not participating in an
exercise program (P>.05) (fig 3). In the subjective measures, the
mean improvements in scores of physical functioning and symp-
toms varied from 49% to 127% from preoperative to 3 months
(P<.001). From 3 to 12 months, further improvements of 8% to
23% were found (P<.001).
The preoperative 6MWT was correlated with changes in the
6MWT at 3 months (rZ.59, P<.001) and with changes at
12 months (rZ.55, P<.001). Patients with low preoperative
6MWT score were likely to do better than preoperatively in the
6MWT at 3 months (see fig 1), while those with a high preoper-
ative 6MWT score needed a longer time to regain their score (see
figs 1 and 2). At 12 months, nearly all the patients had regained
and improved their preoperative 6MWT score. Those with low
preoperative scores achieved the largest gains (see fig 2).
Predictors of walking distance at 3 and 12 months
after THA
There were statistically significant differences between men and
women in preoperative scores of the 6MWT (PZ.05); SCT (PZ.01);
HOOS pain (PZ.04), activities of daily living (PZ.03), and sport
(PZ.03); and body mass index (PZ.04) and the 6MWT score at 3
(P<.001) and 12 months (PZ.04). The variables of patient charac-
teristics and preoperative measures of physical functioning, which
correlated statistically significantly with the 6MWT at 3 months, are
shown in table 3. The correlations showed almost a similar picture at
12 months (data not shown). Based on the correlation analyses, 5
predictive variables were included in the regression analyses.
Age, sex, preoperative 6MWT, and hip ROM were associated
with the outcome in the 6MWT at 3 and 12 months (P.01), and
in addition, the exercise program contributed at 12 months
(P<.001) (table 4). The total adjusted models explained 37% of
the variance at 3 months and 47% at 12 months (P<.001).
Discussion
The objective measures of physical functioning showed small but
gradual improvements during 12 months, while the subjective
measures of physical functioning had improved substantially at
3 months with small further improvements at 12 months. Age, sex,
preoperative walking distance, and hip flexibility explained 37%
of the variance in the 6MWT score at 3 months, and at 12 months,
the exercise program, age, sex, preoperative walking distance, and
hip flexibility explained 47% of the variance.
The present discrepancy in the recovery patterns evaluated by
objective and subjective measures is in accordance with some
previous studies,
6,8,12,40
but in contrast to 2 studies in which most
improvements in both objective and subjective measures occurred
during the first 3 months after surgery.
14,15
In these 2 studies, the
preoperative walking distance appeared to be shorter than for the
total sample in our study. We also found that the subgroup that had
the most limited walking distance preoperatively got the most
considerable gain at 3 months, while less improvement occurred
further on in the recovery course. Thus, it seems that the recovery
pattern in objective measures may differ depending on the
preoperative status of physical functioning. With respect to
subjective measures, there was an agreement across prior
studies
5,10
and our study that a large early improvement in
subjective measures can be expected after surgery. We agree with
prior authors that a plausible explanation can be that the
Table 1 Characteristics of patients with THA
Characteristics
Participants
Completing
Assessments
at 3mo (nZ88)
Participants
Completing
Assessments
at 12mo (nZ64)
Age (y), mean (95% CI) 66 (64e68) 65 (64e67)
Body mass index, mean
(95% CI)
27 (26e27) 27 (26e28)
Females 51 (58) 34 (52)
Educational level 12y 39 (44) 27 (42)
Educational level 13y 49 (56) 37 (58)
Married/cohabiting 61 (69) 50 (77)
Exeter prosthesis 66 (75) 47 (73)
Spectron prosthesis 22 (25) 17 (27)
Physiotherapy 0e3mo 69 (78) 46 (71)
Physiotherapy 3e5mo NA 32 (50)
Comorbidity
Heart attack 2 (2) 0 (0)
Angina 1 (1) 0 (0)
Diabetes 1 (1) 0 (0)
Cancer 4 (5) 3 (5)
Osteoporosis 4 (5) 2 (3)
Musculoskeletal disorders 10 (11) 9 (14)
Stomach/intestinal
problems
5 (6) 4 (6)
Lung disease 2 (2) 1 (2)
Psychological disorder 1 (1) 1 (2)
NOTE. Values are n (%) or as otherwise indicated.
Abbreviations: CI, confidence interval; NA, not applicable.
Recovery and prediction after total hip arthroplasty 1355
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substantial pain relief obtained in our study may have influenced
how the patients evaluated their physical functioning.
12
Moreover,
the high preoperative pain score and the pain relief at 3 months
may also explain the limitation in walking distance in a subgroup
of our patients before surgery and the early substantial improve-
ment in walking distance after surgery.
One question is whether the changes found in both objective
and subjective measures at 3 and 12 months are of any clinical
relevance. According to Perera et al,
24
the change in the 6MWT
score from preoperative to 3 months was considered to be a small
meaningful change, and the change from 3 to 12 months was
substantial. According to Roos and Lohmander,
33
the changes in
the subjective measures of HOOS from preoperative to 3 months
were considered as considerable meaningful changes, while the
changes from 3 to 12 months were of little clinical relevance.
However, the changes in both the objective and subjective
measures after 1 year compared with preoperative scores are of
substantial clinical relevance.
Presently, predictors of postoperative outcome in the 6MWT
were consistently identified among the preoperative objective
measures, while the subjective measures did not contribute in the
models. Better preoperative scores in the 6MWT and hip ROM
were associated with better postoperative scores in the 6MWT. We
have found only 1 recent study that is comparable to our study.
Nankaku et al
41
found that good scores on the objective measure
of ambulation, the timed “Up & Go” test, predicted the likelihood
of not using walking aids 6 months postoperatively. Thus, this
study and ours both suggest that patients’ preoperative physical
functioning matters for how the outcome is likely to become after
surgery. These results indicate that objective measures of physical
functioning can be useful in helping clinicians to set attainable
therapeutic goals. One can also speculate how exercises to
improve physical functioning may have an influence on outcome
in ambulation after surgery. Our model explained approximately
half of the variance in walking distance, and several other plau-
sible aspects, such as psychological and social aspects, may play
an additional role.
20
More research is needed to examine how
people’s physical functioning and other variables may predict the
postoperative outcome, and whether preoperative intervention
may have an influence on outcome after THA.
Study limitations
The internal validity of the study has to be discussed. In our
design, we have measured the outcomes only 3 times, and it is
likely that we may have overlooked an early postoperative decline,
but more importantly, a plateau of the improvements between 3
and 12 months, as reported by others.
6,42
With respect to the subjective measures, a ceiling effect may
have occurred because the patients tended to have early high
scores on subjective measures, leading to only limited possibilities
for a similar increase at 12 months. In these self-reports, several
questions address the ability to perform self-care activities, but
other subjective measures including more questions about the
Fig 3 Mean (95% CI) walking distance in the 6MWT preoperatively
(nZ64), at 3 months (nZ64), and at 12 months after THA in the
nonexercise group (black, nZ32) and the exercise group (white,
nZ32). Abbreviation: CI, confidence interval.
Table 2 Recovery of physical functioning in patients from before to 3 and 12mo after THA (nZ64)
Variables
Mean (95% CI) PValue for:
Before Surgery 3mo After Surgery 12mo After Surgery Overall Time Effect
Differences From
Before Surgery to 3mo
Differences
From 3 to 12mo
Objective measures
6MWT (m) 401 (377e425) 437 (416e458) 512 (490e534) <.001 .007 <.001*
SCT (s) 14 (13e16) 13 (12e13) 11 (10e12) <.001 .046 <.001
Fig. 8 (steps) 10 (6e14) 10 (6e13) 7 (4e10) .002 1.000 .001
IMF 13 (11e15) 12 (11e14) 8 (7e10) <.001 .722 <.001
Hip ROM () 81 (77e85) 84 (81e87) 94 (91e98) <.001 .068 <.001
Subjective measures
HHS 57 (53e61) 85 (82e87) 94 (92e96) <.001 <.001 <.001
HOOS symptoms 48 (45e52) 77 (75e80) 86 (83e89) <.001 <.001 <.001
HOOS pain 52 (48e55) 87 (84e90) 94 (92e96) <.001 <.001 <.001
HOOS ADL 56 (53e60) 84 (81e86) 92 (89e94) <.001 <.001 <.001
HOOS sport 35 (30e40) 64 (59e70) 79 (74e84) <.001 <.001 <.001
HOOS QOL 30 (26e34) 68 (64e73) 82 (78e86) <.001 <.001 <.001
Abbreviations: ADL, activities of daily living; CI, confidence interval; Fig. 8, figure-of-eight test; HHS, Harris Hip Score; QOL, quality of life.
* Significant interaction between the 6MWT at 12mo and the exercise variable (PZ.002).
1356 K.E. Heiberg et al
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patients’ ability to participate in more demanding leisure activities
may have depicted another recovery pattern.
One important issue to be discussed is how the participation
in a 6-week exercise program starting 3 months postoperatively
may have influenced our conclusions. In the statistical analysis,
we adjusted for the role of the exercise program. No statistically
significant differences between the exercise and nonexercise
groups were found at 12 months, and figure 3 illustrates that
the difference between groups was small. Therefore, it seems
unlikely that this has undermined the validity of our
conclusions.
Another important question is whether our results can be
generalized. The patients were asked to participate in a training
study, which may have given us a selected group that was healthier
and more motivated for physical activity than the general THA
population. They had few comorbidities and performed relatively
well on preoperative 6MWT when compared with patients in other
studies.
4,11
With respect to age, they were a few years younger than
Table 3 Bivariate correlation matrix between the 6MWT at 3mo postoperatively and the control variables and plausible preoperative
predictive variables in patients with THA (nZ88)
Variables 6MWT at 3mo 6MWT SCT Fig. 8 Hip ROM HOOS Pain HOOS ADL
HOOS
Sport HHS BMI
Age .22*.10 .08 .33
y
.17 .13 .09 .12 .03 .21
BMI .04 .24*.15 .06 .28
y
.15 .28
y
.18 .23*
HHS .24*.60
z
.47
z
.11 .21 .65
z
.67
z
.53
z
HOOS sport .33
y
.47
z
.37
z
.15 .16 .63
z
.72
z
HOOS ADL .29
y
.50
z
.33
y
.05 .18 .75
z
HOOS pain .15 .41
z
.30
y
.01 .25*
Hip ROM .23*.27
y
.11 .27*
Fig. 8 .27*.28
y
.14
SCT .42
z
.59
z
6MWT .47
z
Abbreviations: ADL, activities of daily living; BMI, body mass index; Fig. 8, figure-of-eight test; HHS, Harris Hip Score.
* Pearson’s correlation coefficient; P<.05.
y
Pearson’s correlation coefficient; P<.01.
z
Pearson’s correlation coefficient; P<.001.
Table 4 Preoperative predictors of walking distance outcomes in patients at 3mo (nZ88) and at 12mo (nZ64) after THA
Variables
Crude Estimates Adjusted Estimates
b95% CI Pb95% CI P
6MWT at 3mo
Age (y) 2.2 4.2 to 0.2 .030 2.5 4.3 to 0.6 .009
Sex (women [reference]/men) 61.5 30.4 to 92.5 <.001 65.3 34.8 to 95.9 <.001
Harris Hip Score 1.0 2.2 to 0.3 .119
Preoperative physical functioning variables
6MWT 0.2 0.0 to 0.4 .069 0.3 0.1 to 0.4 .002
SCT (s) 2.6 6.0 to 0.8 .126
Figure-of-eight test (steps) 0.6 1.8 to 0.7 .393
Active Hip ROM () 1.1 0.2 to 2.1 .017 1.2 0.3 to 2.1 .010
HOOS sport/recreation 0.6 0.2 to 1.4 .157
6MWT at 12mo
Age (y) 2.1 4.8 to 0.6 .118 3.1 5.5 to 0.8 .009
Sex (women [reference]/men) 60.5 21.4 to 99.5 .003 60.3 22.9 to 97.7 .002
Harris Hip Score 0.4 1.0 to 1.8 .582
Exercise (yes [reference]/no) 69.8 108.3 to 31.3 .001 70.3 104.8 to 35.8 <.001
Preoperative physical funtioning variables
6MWT 0.2 0.1 to 0.4 .189 0.3 0.1 to 0.5 .004
SCT (s) 2.3 6.3 to 1.6 .242
Figure-of-eight test (steps) 1.3 2.8 to 0.2 .089
Active Hip ROM () 1.5 0.2 to 2.9 .025 2.0 0.8 to 3.3 .002
HOOS sport/recreation 0.3 1.2 to 0.6 .534
NOTE. Unstandardized beta, 95% CI, and Pvalue given for crude and adjusted estimates in the multiple regression analyses. The total model explained
37% of the variance in the 6MWT at 3mo (adjusted R
2
Z.37) and 47% of the variance in the 6MWT at 12mo after surgery (adjusted R
2
Z.47).
Abbreviation: CI, confidence interval.
Recovery and prediction after total hip arthroplasty 1357
www.archives-pmr.org
the Norwegian THA population.
43
However, the patients included in
a review examining recovery seemed to cover almost the same age
span as our patients.
13
Thus, our study seems comparable to other
studies, and it may also reflect that hip arthroplasty is offered to
younger and healthier patients than previously described.
44
A high number of patients did not turn up for assessments,
which may have biased the results. At 3 months, those with the
worse preoperative pain and functioning withdrew, but those not
turning up for the 12-month assessments did not differ from the
others either at preoperative or 3-month scores. Anyway, we
believe that our patients represent a relatively healthy and physi-
cally fit sample and that these results can be generalized to
similar patients.
Conclusions
After THA, the patients’ objective measures of physical func-
tioning improved slowly throughout the first postoperative year,
while the subjective measures showed early substantial improve-
ments and only slight further improvements the following months.
Younger age, male sex, and better scores on walking distance and
hip flexibility before surgery predicted better score on walking
distance following THA.
Suppliers
a. Exeter Hip Unit, Princess Elizabeth Orthopaedic Hospital,
RD&E, Barrack Road, Exeter, EX2 5DW.
b. Smith & Nephew, Advanced Surgical Devices, 1450 Brooks
Rd, Memphis, TN 38116.
Keywords
Arthroplasty, replacement, hip; Recovery of function;
Rehabilitation; Walking
Corresponding author
Kristi Elisabeth Heiberg, MSc, Department of Health Sciences,
Institute of Health and Society, University of Oslo, P.O. Box 1089,
Blindern, N-0317 Oslo, Norway. E-mail address: k.e.heiberg@
medisin.uio.no.
Acknowledgments
We thank physiotherapist Mary Deighan Hansen, RPt, at Martina
Hansen’s Hospital and physiotherapist Anne Gunn Kallum, RPt,
at Bærum Hospital, Vestre Viken Hospital Trust, for all their
efforts in recruiting the patients, performing the measurements,
and collecting the data. We also thank the physiotherapy staff at
the hospitals for their participation.
References
1. Bijlsma JW, Berenbaum F, Lafeber FP. Osteoarthritis: an update with
relevance for clinical practice. Lancet 2011;377:2115-26.
2. Ahmad MA, Xypnitos FN, Giannoudis PV. Measuring hip outcomes:
common scales and checklists. Injury 2011;42:259-64.
3. Jones CA, Beaupre LA, Johnston DW, Suarez-Almazor ME. Total
joint arthroplasties: current concepts of patient outcomes after surgery.
Rheum Dis Clin North Am 2007;33:71-86.
4. Naylor JM, Harmer AR, Heard RC, Harris IA. Patterns of recovery
following knee and hip replacement in an Australian cohort. Aust
Health Rev 2009;33:124-35.
5. Bachmeier CJ, March LM, Cross MJ, et al. A comparison of outcomes
in osteoarthritis patients undergoing total hip and knee replacement
surgery. Osteoarthritis Cartilage 2001;9:137-46.
6. Kennedy DM, Stratford PW, Hanna SE, Wessel J, Gollish JD.
Modeling early recovery of physical function following hip and knee
arthroplasty. BMC Musculoskelet Disord 2006;7:100.
7. Ashby E, Grocott MP, Haddad FS. Outcome measures for orthopaedic
interventions on the hip. J Bone Joint Surg Br 2008;90:545-9.
8. Stratford PW, Kennedy DM. Performance measures were necessary to
obtain a complete picture of osteoarthritic patients. J Clin Epidemiol
2006;59:160-7.
9. van den Akker-Scheek I, Stevens M, Bulstra SK, Groothoff JW,
van H Jr, Zijlstra W. Recovery of gait after short-stay total hip
arthroplasty. Arch Phys Med Rehabil 2007;88:361-7.
10. Lindemann U, Becker C, Unnewehr I, et al. Gait analysis and
WOMAC are complementary in assessing functional outcome in total
hip replacement. Clin Rehabil 2006;20:413-20.
11. Boardman DL, Dorey F, Thomas BJ, Lieberman JR. The accuracy of
assessing total hip arthroplasty outcomes: a prospective correlation
study of walking ability and 2 validated measurement devices.
J Arthroplasty 2000;15:200-4.
12. van den Akker-Scheek I, Zijlstra W, Groothoff JW, Bulstra SK,
Stevens M. Physical functioning before and after total hip
arthroplasty: perception and performance. Phys Ther 2008;88:
712-9.
13. Vissers MM, Bussmann JB, Verhaar JA, Arends LR, Furlan AD,
Reijman M. Recovery of physical functioning after total hip arthro-
plasty: systematic review and meta-analysis of the literature. Phys
Ther 2011;91:615-29.
14. de Groot IB, Bussmann HJ, Stam HJ, Verhaar JA. Small increase of
actual physical activity 6 months after total hip or knee arthroplasty.
Clin Orthop Relat Res 2008;466:2201-8.
15. Laupacis A, Bourne R, Rorabeck C, et al. The effect of elective total
hip replacement on health-related quality of life. J Bone Joint Surg
Am 1993;75:1619-26.
16. Wang W, Morrison TA, Geller JA, Yoon RS, Macaulay W. Predicting
short-term outcome of primary total hip arthroplasty: a prospective
multivariate regression analysis of 12 independent factors. J Arthro-
plasty 2010;25:858-64.
17. Nilsdotter AK, Petersson IF, Roos EM, Lohmander LS. Predictors of
patient relevant outcome after total hip replacement for osteoarthritis:
a prospective study. Ann Rheum Dis 2003;62:923-30.
18. Mahomed NN, Liang MH, Cook EF, et al. The importance of patient
expectations in predicting functional outcomes after total joint
arthroplasty. J Rheumatol 2002;29:1273-9.
19. Judge A, Javaid MK, Arden NK, et al. Clinical tool to identify patients
who are most likely to achieve long-term improvement in physical
function after total hip arthroplasty. Arthritis Care Res (Hoboken)
2012;64:881-9.
20. Brueilly KE, Pabian PS, Straut LC, Freve LA, Kolber MJ. Factors
contributing to rehabilitaion outcomes following total hip arthroplasty.
Phys Ther Rev 2012;17:301-10.
21. Mancuso CA, Jout J, Salvati EA, Sculco TP. Fulfillment of patients’
expectations for total hip arthroplasty. J Bone Joint Surg Am 2009;91:
2073-8.
22. Heiberg KE, Bruun-Olsen V, Ekeland A, Mengshoel AM. Effect of
a walking skill training program in patients who have undergone total
hip arthroplasty: follow-up one year after surgery. Arthritis Care Res
(Hoboken) 2012;64:415-23.
23. Guyatt GH, Sullivan MJ, Thompson PJ, et al. The 6-minute walk:
a new measure of exercise capacity in patients with chronic heart
failure. Can Med Assoc J 1985;132:919-23.
1358 K.E. Heiberg et al
www.archives-pmr.org
24. Perera S, Mody SH, Woodman RC, Studenski SA. Meaningful change
and responsiveness in common physical performance measures in
older adults. J Am Geriatr Soc 2006;54:743-9.
25. Kennedy DM, Stratford PW, Wessel J, Gollish JD, Penney D.
Assessing stability and change of four performance measures:
a longitudinal study evaluating outcome following total hip and knee
arthroplasty. BMC Musculoskelet Disord 2005;6:3.
26. Harada ND, Chiu V, Stewart AL. Mobility-related function in older
adults: assessment with a 6-minute walk test. Arch Phys Med Rehabil
1999;80:837-41.
27. Noren AM, Bogren U, Bolin J, Stenstrom C. Balance assessment in
patients with peripheral arthritis: applicability and reliability of some
clinical assessments. Physiother Res Int 2001;6:193-204.
28. Ekdahl C, Andersson SI, Svensson B. Muscle function of the lower
extremities in rheumatoid arthritis and osteoarthrosis: a descriptive
study of patients in a primary health care district. J Clin Epidemiol
1989;42:947-54.
29. Ekdahl C, Englund A, Stenstro
¨m CH. Development and evaluation of
the Index of Muscle Function. Adv Physiother 1999;1:45-53.
30. Norkin CC, White DJ. Measurement of joint motion: A guide to
goniometry. 2nd ed. Philadelphia: F.A. Davis; 1995.
31. Harris WH. Traumatic arthritis of the hip after dislocation and
acetabular fractures: treatment by mold arthroplasty. An end-result
study using a new method of result evaluation. J Bone Joint Surg
Am 1969;51:737-55.
32. Soderman P, Malchau H. Is the Harris hip score system useful to study the
outcome of total hip replacement? Clin Orthop Relat Res 2001;384:189-97.
33. Roos EM, Lohmander LS. The Knee injury and Osteoarthritis
Outcome Score (KOOS): from joint injury to osteoarthritis. Health
Qual Life Outcomes 2003;1:64.
34. Beaton DE, Bombardier C, Guillemin F, Ferraz MB. Guidelines for
the process of cross-cultural adaptation of self-report measures. Spine
2000;25:3186-91.
35. Nilsdotter AK, Lohmander LS, Klassbo M, Roos EM. Hip disability
and osteoarthritis outcome score (HOOS)evalidity and respon-
siveness in total hip replacement. BMC Musculoskelet Disord 2003;
4:10.
36. Arthursson AJ, Furnes O, Espehaug B, Havelin LI, Soreide JA.
Prosthesis survival after total hip arthroplasty edoes surgical
approach matter? Analysis of 19,304 Charnley and 6,002 Exeter
primary total hip arthroplasties reported to the Norwegian Arthro-
plasty Register. Acta Orthop 2007;78:719-29.
37. Brander VA, Mullarkey CF. Rehabilitation after total hip replace-
ment for osteoarthritis. Phys Med Rehabil State Art Rev 2002;16:
415-30.
38. Moons KG, Royston P, Vergouwe Y, Grobbee DE, Altman DG.
Prognosis and prognostic research: what, why, and how? BMJ 2009;
338:b375.
39. Kvien TK, Kaasa S, Smedstad LM. Performance of the Norwegian
SF-36 Health Survey in patients with rheumatoid arthritis, II:
a comparison of the SF-36 with disease-specific measures. J Clin
Epidemiol 1998;51:1077-86.
40. Hodt-Billington C, Helbostad JL, Vervaat W, Rognsvag T, Moe-
Nilssen R. Changes in gait symmetry, gait velocity and self-reported
function following total hip replacement. J Rehabil Med 2011;43:
787-93.
41. Nankaku M, Tsuboyama T, Akiyama H, et al. Preoperative prediction
of ambulatory status at 6 months after total hip arthroplasty. Phys Ther
2013;93:88-93.
42. Kennedy DM, Stratford PW, Robarts S, Gollish JD. Using outcome
measure results to facilitate clinical decisions the first year after total
hip arthroplasty. J Orthop Sports Phys Ther 2011;41:232-9.
43. Norwegian Arthroplasty Register. Available at: http://nrlweb.ihelse.
net/Rapporter/Rapport2012.pdf. Accessed October 11, 2012.
44. Learmonth ID, Young C, Rorabeck C. The operation of the century:
total hip replacement. Lancet 2007;370:1508-19.
Recovery and prediction after total hip arthroplasty 1359
www.archives-pmr.org
... Approximately 10-25% of people with bilateral degenerative joint disease of the hip undergo bilateral total hip replacement surgery [3,[7][8][9]11]. There is no 'gold standard' for the management of patients with bilateral osteoarthritis of the hip [3][4][5][6][7][8][9][10][11][12][13][14][15][16][17][18][19][20]. Some orthopedic surgeons prefer a simultaneous (one-stage) bilateral total hip arthroplasty [6,9,10,[12][13][14][15]20], whereas others prefer a two-stage procedure, which involves operating on one hip joint at a time [3,4,7]. ...
... There is no 'gold standard' for the management of patients with bilateral osteoarthritis of the hip [3][4][5][6][7][8][9][10][11][12][13][14][15][16][17][18][19][20]. Some orthopedic surgeons prefer a simultaneous (one-stage) bilateral total hip arthroplasty [6,9,10,[12][13][14][15]20], whereas others prefer a two-stage procedure, which involves operating on one hip joint at a time [3,4,7]. ...
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Background: Approximately 10–25% of total hip replacement patients undergo a bilateral procedure. The purpose of this study was to compare selected parameters associated with the first and second hip arthroplasty in patients undergoing two-stage treatment due to bilateral hip osteoarthritis and establish the predictive factors for the second procedure. Methods: This study compared the data on bilateral total hip replacement surgeries conducted in the period between 2017 and 2021 (42 patients). The following parameters from the first and second procedure were compared: the prosthetic stem, head, and insert cup size; type of cup insert; duration of anesthesia; duration of hospitalization; and the number of complications. Results: The mean duration of hospital stay at the time of the first total hip arthroplasty was 5.83 days and 5.4 days during the second stay. The mean stem sizes used during the first and second total hip replacement procedures were 7.11 and 7.09, respectively. The mean sizes of endoprosthetic cups used at the first and second total hip replacement procedures were 52.64 and 53.04, respectively. There were no significant differences between the mean prosthetic head size at the first and second surgery. The cup type used during the first and second surgery showed no difference. The mean duration of anesthesia used during the first and second total hip replacement surgery was 108.09 min and 104.52 min, respectively. We recorded a mean of 0.07 complications per patient at the first surgery and 0.02 at the second surgery. Conclusions: Our study results showed symmetry duration of anesthesia, length of hospital stay, number of complications per patient, stem size, prosthetic head size, cup insert size, and cup insert type at the first and second surgery in patients with two-stage bilateral total hip arthroplasty. We observed a strong correlation between the stem sizes of the first and second hip endoprostheses. There was also a strong correlation between the cup sizes used during the first and second surgery.
... Total hip arthroplasty (THA) is a successful procedure that provides pain relief, restores function, and improves quality of life (QOL) for patients with advanced arthritis in their hip joint [1][2][3]. Measures of physical functioning show very positive outcomes of THA [4,5]. The recovery trajectory for THA is rapid for physical impairment (by 2 weeks), and almost all patients report improved mood by 1-2 months. ...
... This study examined the role of cognitive appraisal processes in THA outcomes in the first year post-surgery. We focused on one outcome with documented responsiveness to THA (i.e., physical functioning) [4,5] and one that seems to yield relatively small effects after THA (i.e., mental-health functioning) [15]. We hypothesized that appraisal processes would help to explain differences over time in the responsive outcome, and that underlying changes in appraisal processes would clarify lack of change on the non-responsive outcome. ...
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Background Total hip arthroplasty (THA) is a successful procedure that provides pain relief, restores function, and improves quality of life (QOL) for patients with advanced arthritis in their hip joint. To date, little research has examined the role of cognitive appraisal processes in THA outcomes. This study examined the role of cognitive appraisal processes in THA outcomes in the first year post-surgery. Methods This longitudinal cohort study collected data at pre-surgery, 6 weeks post-surgery, 3 months post-surgery, and 12 months post-surgery. Adults (n = 189) with a primary diagnosis of osteoarthritis were consecutively recruited from an active THA practice at a Canadian academic teaching hospital. Measures included the Hip Disability and Osteoarthritis Outcome Score (HOOS), the Mental Component Score (MCS) of the Rand-36, and the Brief Appraisal Inventory (BAI). Analysis of Variance examined the association between BAI items and the HOOS or MCS scores. Random effects models investigated appraisal main effects and appraisal-by-time interactions for selected BAI items. Results HOOS showed great improvement over the first 12 months after THA, and was mitigated by three appraisal processes in particular: focusing on problems with healthcare or living situation, and preparing one’s family for health changes. MCS was stable and low over time, and the following appraisal processes were implicated by very large effect sizes: not comparing themselves to healthier people, focusing on money problems, preparing their family for their health changes, or trying to shed responsibilities. Conclusions Appraisal processes are relevant to health outcomes after THA, with different processes coming into play at different points in the recovery trajectory.
... The late assessments provided additional time for postoperative changes in spinopelvic motion to occur. However, recovery from THA primarily occurs within 12 months or earlier [7,15,33], and further improvements in ROM are unlikely to continue after this date. In fact, postoperative complications and unrelated pathology may reduce ROM. ...
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Background Spinopelvic stiffness (primarily in the sagittal plane) has been identified as a factor associated with inferior patient-reported outcomes (PROs) and increased dislocation risk after THA. Incorporating preoperative spinopelvic characteristics into surgical planning has been suggested to determine a patient-specific cup orientation that minimizes dislocation risk. Sagittal plane radiographic analysis of static postures indicates that patients exhibit a degree of normalization in their spinopelvic characteristics after THA. It is not yet known whether normalization is also evident during dynamic movement patterns, nor whether it occurs in the coronal and axial planes as well. Questions/purposes (1) Does motion capture analysis of sagittal spinopelvic motion provide evidence of normalization after THA? (2) Do changes in coronal and axial plane motion accompany those in the sagittal plane? Methods Between April 2019 and February 2020, 25 patients agreed to undergo motion capture movement analysis before THA for the treatment of hip osteoarthritis (OA). Of those, 20 underwent the same assessment between 8 and 31 months after THA. Five patients were excluded because of revision surgery (n = 1), contralateral hip OA (n = 1), and technical issues with a force plate during post-THA assessment (n = 3), leaving a cohort total of 15 (median age [IQR] 65 years [10]; seven male and eight female patients). A convenience sample of nine asymptomatic volunteers, who were free of hip and spinal pathology, was also assessed (median age 51 years [34]; four male and five female patients). Although the patients in the control group were younger than those in the patient group, this set a high bar for our threshold of spinopelvic normalization, reducing the possibility of false positive results. Three-dimensional motion capture was performed to measure spinal, pelvic, and hip motion while participants completed three tasks: seated bend and reach, seated trunk rotation, and gait on a level surface. ROM during each task was assessed and compared between pre- and post-THA conditions and between patients and controls. Statistical parametric mapping (SPM) was used to assess the timing of differences in motion during gait, and spatiotemporal gait parameters were also measured. Results After THA, patients demonstrated improvements in sagittal spinal (median [IQR] 32° [18°] versus 41° [14°]; difference of medians 9°; p = 0.004), pelvis (25° [21°] versus 30° [8°]; difference of medians 5°; p = 0.02), and hip ROM (21° [18°] versus 27° [10°]; difference of medians 6°; p = 0.02) during seated bend and reach as well in sagittal hip ROM during gait (30° [11°] versus 44° [7°]; difference of medians 14°; p < 0.001) compared with their pre-THA results, and they showed a high degree of normalization overall. These sagittal plane changes were accompanied by post-THA increases in coronal hip ROM (12° [9°] versus 18° [8°]; difference of medians 6°; p = 0.01) during seated trunk rotation, by both coronal (6° [4°] versus 9° [3°]; difference of medians 3°; p = 0.01) and axial (10° [8°] versus 16° [7°]; difference of medians 6°; p = 0.003) spinal ROM, as well as coronal (8° [3°] versus 13° [4°]; difference of medians 5°; p < 0.001) and axial hip ROM (21° [11°] versus 34° [24°]; difference of medians 13°; p = 0.01) during gait compared with before THA. The SPM analysis showed these improvements occurred during the late swing and early stance phases of gait. Conclusion When restricted preoperatively, spinopelvic characteristics during daily tasks show normalization after THA, concurring with previous radiographic findings in the sagittal plane. Thus, spinopelvic characteristics change dynamically, and incorporating them into surgical planning would require predictive models on post-THA improvements to be of use. Level of Evidence Level II, prognostic study.
... 19 From the patients' perspective, perceived physical function and satisfaction with the outcome of THA are essential aspects to consider, primarily as it is known that objectively measured physical function shows only moderate correlations with perceived physical function. [24][25][26][27] Therefore, perceived physical function and satisfaction are the primary outcomes of interest. ...
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Introduction Total hip arthroplasty (THA) is the treatment of choice for end-stage osteoarthritis of the hip. Management of THA differs between countries, and it is hypothesised that this can influence patients’ expectations and self-efficacy. Using Chen’s intervening mechanism evaluation approach, this study aims to explore how structure of care influences expectations and self-efficacy of patients undergoing THA, and how expectations and self-efficacy in turn influence outcome in terms of perceived physical function and satisfaction. Methods and analysis A mixed-methods study will be conducted in two German and two Dutch hospitals near the Dutch-German border. In the quantitative part, patients will complete questionnaires at three timepoints: preoperatively and at 3 and 6 months postoperatively. Data analysis will include multiple regression analysis and structural equation modelling. In the qualitative part, interviews will be held with patients (preoperatively and 3 months postoperatively) and healthcare providers. Analysis will be performed using structured qualitative content analysis. Ethics and dissemination The study is approved by the Institutional Review Boards of both Carl von Ossietzky University Oldenburg (2021–167) and University Medical Center Groningen (METc 2021/562 and METc 2021/601). The results will be disseminated in the international scientific community via publications and conference presentations. Trial registration number The study is registered in the German Clinical Trials Registry (DRKS: DRKS00026744).
... Many of these studies, use a variety of Patient-Reported Outcome Measures (PROMs) as the basis to assess functional outcomes [26,27,30] . Although various PROMs have been widely used due to cost-effectiveness and ease of administration, it can be argued that the reported results may be constrained by the subjective nature, ceiling effect, and inadequate sensitivity of various PROMs to determine the true extent of the patient's functional ability [26][27][28][29][30][34][35][36][37][38][39][40] . Additionally, regardless of the type of approach used, several studies report persistent pain, muscle strength deficits, and abnormal movement patterns post-operatively though the patients are considered "rehabilitated" [32,[41][42][43][44][45][46][47] . ...
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Background: Persistent functional abnormalities and strength deficits are commonly reported despite the advances in surgical approaches for primary total hip arthroplasty (THA). Understanding the influence of different approaches on hip muscle strength changes following THA may play a crucial role in optimizing post-operative recovery. Aim: Systematic review and meta-analysis of between-approach comparison of directly measured hip muscle strength following primaryTHA. Method: A comprehensive online database search was performed, identifying studies that compare muscle strength between at least two different THA approaches. Based on Cochrane guidelines, a qualitative and quantitative analysis was completed along with a meta-analysis of the eligible studies. ROBINS-i and ROB-2 were used to analyse the risk of bias, and the Pedro tool was used for quality appraisal. Results: 881 publications were appraised, yielding 23 eligible publications. Sufficient data for analysis was found only between posterior and lateral approaches for hip abduction strength in all categories. No statistically significant difference was found between the two approaches at 12 months and over time-period following THA (Z=1.51, P=0.13, Std Mean diff = 0.24, 95% CI [-.07,.56]). However, the results slightly favoured posterior approach. Additionally, no statistically significant difference found in the strength ratio of the operated side to the unoperated side (U = 15, z = -0.52, p = 0.69) or in the percentage change in muscle strength at 3 months (U=10, z=-.577, p=0.686) and 12 months (U = 10, z=-.577, p = 0.686) from pre-operative baseline. Conclusion: This systematic review and meta-analysis found no statistically significant difference between posterior and lateral approaches for directly measured hip muscle strength measured. Despite the increasing popularity of AA, ALA, and other minimally invasive or modified approaches, and the relationship between muscle strength and function, a sparsity was identified in published studies that performed a comparison between approaches of hip muscle strength.
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Unlabelled: Traditional risk factors used for predicting poor postoperative recovery have focused on postoperative complications, adverse symptoms (nausea, pain), length of hospital stay, and patient quality of life. Despite these being traditional performance indicators of patient postoperative "status," they may not fully define the multidimensional nature of patient recovery. The definition of postoperative recovery is thus evolving to include patient-reported outcomes that are important to the patient. Previous reviews have focused on risk factors for the above traditional outcomes after major surgery. Yet, there remains a need for further study of risk factors predicting multidimensional patient-focused recovery, and investigation beyond the immediate postoperative period after patients are discharged from the hospital. This review aimed to appraise the current literature identifying risk factors for multidimensional patient recovery. Methods: A systematic review without meta-analysis was performed to qualitatively summarize preoperative risk factors for multidimensional recovery 4-6 weeks after major surgery (PROSPERO, CRD42022321626). We reviewed three electronic databases between January 2012 and April 2022. The primary outcome was risk factors for multidimensional recovery at 4-6 weeks. A GRADE quality appraisal and a risk of bias assessment were completed. Results: In total, 5150 studies were identified, after which 1506 duplicates were removed. After the primary and secondary screening, nine articles were included in the final review. Interrater agreements between the two assessors for the primary and secondary screening process were 86% (k = 0.47) and 94% (k = 0.70), respectively. Factors associated with poor recovery were found to include ASA grade, recovery tool baseline score, physical function, number of co-morbidities, previous surgery, and psychological well-being. Mixed results were reported for age, BMI, and preoperative pain. Due to the observational nature, heterogeneity, multiple definitions of recovery, and moderate risk of bias of the primary studies, the quality of evidence was rated from very low to low. Conclusion: Our review found that there were few studies assessing preoperative risk factors as predictors for poor postoperative multidimensional recovery. This confirms the need for higher quality studies assessing risk for poor recovery, ideally with a consistent and multi-dimensional definition of recovery.
Article
Objective: To determine the reproducibility, criterion-related validity, and minimal clinically important difference (MCID) of the stair negotiation test (SNT) after total hip arthroplasty (THA). Methods: Sixty patients who underwent THA were included in this study. They performed the SNT and rated their difficulty in stair negotiation (question 7 of the Oxford Hip Score [OHSQ7]) before and 6 months after surgery. The SNT determined the time taken by a patient to ascend, turn around, and descend the stairs (15 cm × 4 steps) and was measured twice each time. As a measure of reproducibility, the intraclass correlation coefficient (ICC1,1) was calculated using the preoperative SNT. As an index of criterion-related validity, Spearman's rank correlation coefficient was used to evaluate the relationship between the better score of two trials in the preoperative SNT and the OHSQ7. The MCID of the SNT was calculated using the distribution-based method and the anchor-based method. The change in the OHSQ7 between before and after surgery was used as an anchor in the latter method. Results: The ICC1,1 of the SNT was 0.97. The SNT was significantly correlated with the OHSQ7 (r = 0.40, p < .05). Moreover, the anchor-based MCID of the SNT was 1.98 seconds. Conclusion: The SNT is an objective assessable test of stair negotiation ability in post-THA patients that has good reproducibility and moderate criterion-related validity. Changes in the SNT beyond the MCID (1.98 seconds) represent clinically important changes in stair negotiation ability.
Article
Introduction: Hip osteoarthritis (OA) with acetabular dysplasia negatively affects pelvic alignment and muscle function. We aimed to investigate the changes in muscle atrophy and fatty infiltration of the hip and trunk muscles 1 year after total hip arthroplasty (THA) in patients with hip OA with acetabular dysplasia. Methods: This study included 51 female patients who underwent THA for unilateral hip OA with acetabular dysplasia. The cross-sectional area (CSA) and muscle density of the gluteus maximus, gluteus medius, gluteus minimus, piriformis, iliopsoas, rectus abdominis, and abdominal oblique muscles using computer tomography and pelvic inclination angle using radiographs were assessed before and 1 year after THA. Results: At the 1-year follow-up, the CSA and muscle density of the gluteus medius (2,078 to 2,522 mm2 and 30.3 to 39.4 hounsfield units [HU]), iliopsoas (715 to 901 mm2 and 40.3 to 50.8 HU), and rectus abdominis (336 to 363 mm2 and 28.6 to 30.6 HU) of the affected limb had increased significantly (P < 0.05). The CSA and muscle density of the gluteus maximus (2,429 versus 2,884 mm2 and 23.7 versus 32.6 HU), gluteus minimus (636 versus 785 mm2 and 14.3 versus 37.1 HU), piriformis (505 versus 607 mm2 and 23.4 versus 31.6 HU), and iliopsoas (901 versus 997 mm2 and 50.8 versus 54.5 HU) in the affected limb were lower than those in the unaffected limb (P < 0.01). Postoperatively, the CSA and muscle density of the rectus abdominis were not significantly different between the limbs, and the pelvic inclination angle (35.2° to 32.1°, P < 0.01) was significantly decreased. Discussion: Compared with the nonoperated limb, substantial atrophy and fatty infiltration of most hip muscles persisted in the operated limb 1 year after THA in patients with acetabular dysplasia; asymmetry in the rectus abdominis muscle fully resolved. In patients with acetabular dysplasia, the surgical technique and postoperative rehabilitation should be further considered to optimize hip muscle recovery.
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Patients after joint arthroplasty tend to be less physically active; however, studies measuring objective physical activity (PA) and sedentary behavior (SB) in these patients provide conflicting results. The aim of this meta-analysis was to assess objectively measured PA, SB and performance at periods up to and greater than 12 months after lower limb arthroplasty. Two electronic databases (PubMed and Medline) were searched to identify prospective and cross-sectional studies from 1 January 2000 to 31 December 2020. Studies including objectively measured SB, PA or specific performance tests in patients with knee or hip arthroplasty, were included in the analyses both pre- and post-operatively. The risk of bias was assessed using the Scottish Intercollegiate Guidelines Network (SIGN). After identification and exclusion, 35 studies were included. The data were analyzed using the inverse variance method with the random effects model and expressed as standardized mean difference and corresponding 95% confidence intervals. In total, we assessed 1943 subjects with a mean age of 64.9 (±5.85). Less than 3 months post-operative, studies showed no differences in PA, SB and performance. At 3 months post-operation, there was a significant increase in the 6 min walk test (6MWT) (SMD 0.65; CI: 0.48, 0.82). After 6 months, changes in moderate to vigorous physical activity (MVPA) (SMD 0.33; CI: 0.20, 0.46) and the number of steps (SMD 0.45; CI: 0.34, 0.54) with a large decrease in the timed-up-and-go test (SMD −0.61; CI: −0.94, −0.28) and increase in the 6MWT (SMD 0.62; CI: 0.26–0.98) were observed. Finally, a large increase in MVPA (SMD 0.70; CI: 0.53–0.87) and a moderate increase in step count (SMD 0.52; CI: 0.36, 0.69) were observed after 12 months. The comparison between patients and healthy individuals pre-operatively showed a very large difference in the number of steps (SMD −1.02; CI: −1.42, −0.62), but not at 12 months (SMD −0.75; −1.89, 0.38). Three to six months after knee or hip arthroplasty, functional performance already exceeded pre-operative levels, yet PA levels from this time period remained the same. Although PA and functional performance seemed to fully restore and exceed the pre-operation levels at six to nine months, SB did not. Moreover, PA remained lower compared to healthy individuals even longer than twelve months post-operation. Novel rehabilitation protocols and studies should focus on the effects of long-term behavioral changes (increasing PA and reducing SB) as soon as functional performance is restored.
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Background: Total hip arthroplasty (THA) is an effective procedure that provides patients with long-term relief from pain and enables them to resume their normal daily activities. Preoperative instruction about the functional outcomes and optimum goal of rehabilitation is helpful for patients undergoing THA. Objective: The purposes of this study were: (1) to examine the relationships between preoperative physical functions and ambulation following THA and (2) to identify optimal cutoff values for estimating ambulatory status at 6 months after THA. Design: This was a retrospective study. Methods: The study participants were 204 patients who underwent a unilateral THA. Hip abductor and knee extensor strength were measured and the Timed "Up & Go" Test (TUG) was conducted preoperatively. The patients were divided into 2 groups according to self-reported walking ability at 6 months postoperatively: an independent ambulation group (n=118) and a cane-assisted ambulation group (n=86). Differences between the 2 groups were examined using an unpaired t test or the chi-square test. A stepwise multiple logistic regression analysis was performed with walking ability at 6 months postoperatively as a dependent variable and age, sex, contralateral hip osteoarthritis (ie, whether a participant had contralateral hip osteoarthritis or not), body mass index, hip abductor strength, knee extensor strength, and TUG score as independent variables. Receiver operating characteristic curve analysis was used to identify a cutoff point for classifying the participants into the 2 groups. Results: A stepwise multiple logistic regression analysis selected 3 factors (age, knee extensor strength, and TUG score) as significant variables affecting the midterm ambulatory ability after THA. Moreover, receiver operating characteristic curve analyses revealed that the midterm (ie, 6-month) ambulatory status after THA was more accurately predicted by the patient's TUG score (cutoff point=10 seconds, sensitivity=76.7%, specificity=93.2%, area under the curve=0.93) than by age and knee extensor strength. Limitations: The categorization of ambulatory status in this study was based solely on self-reported walking ability. Conclusion: The findings indicate that patients with a preoperative TUG score of less than 10 seconds are likely to walk without an assistive device at 6 months after THA.
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Background: Hip arthroplasty (HA) is a common surgical procedure with estimated 230 000 procedures performed in the USA in 2008. Projections indicate that the number of procedures will increase to 572 000 by 2030, thus it is important for rehabilitation professionals involved in the care of these individuals to recognize factors that may influence outcomes a priori . Objectives: The objective of this manuscript is to review variables that influence patient outcomes following HA. All relevant literature will be reviewed for interpretation by the healthcare provider to design optimal plans of care and for determining an accurate patient prognosis. Major findings: Evidence suggests that age, gender, body mass index, depression, and smoking status may influence outcomes. Additionally, pre-operative functional ability, type of pain medication, and the use of a clinical pathway appear to influence post-operative outcomes. Further research is needed to determine the effect of specific interventions commonly employed in the rehabilitation setting. Conclusions: Evidence suggests that no one factor may determine an individual’s prognosis following HA. Rather, an individual’s ability to achieve outcomes must be viewed from a multifactorial perspective that takes into account both intrinsic and extrinsic variables.
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To identify an assessment tool and its cut-off point for indicating ambulatory status 6 months after total hip arthroplasty (THA). Cross-sectional study. Kyoto University Hospital. Eighty-eight patients who underwent unilateral THA. Lower-extremity muscle strength, hip range of motion and hip pain were measured 6 months after THA. The patients were divided into two groups according to their ability to walk 6 months after THA: an independent ambulation group and a cane-assisted ambulation group. A stepwise multiple logistic regression analysis indicated that age and lower-extremity maximal load were significant variables affecting mid-term ambulatory status following THA. Receiver operating characteristic curve analyses revealed that ambulatory status following THA was indicated more accurately by leg extension strength (cut-off point=8.24N/kg, sensitivity=92%, specificity=82%, area under the curve=0.93) than age. Lower-limb load force with a cut-off point of 8.24N/kg is a reliable assessment tool for indicating ambulatory status 6 months after primary THA.
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The Western Ontario and McMaster University Osteoarthritis Index (WOMAC) and the SF-36 are used to assess subjective outcome after total hip arthroplasty (THA). Although these indices have been validated, neither the WOMAC nor the SF-36 has been tested for accuracy against objective data in this clinical setting. Thirty osteoarthritic patients undergoing elective primary THA were subjectively evaluated preoperatively and 1 year posteoperatively with the WOMAC and the SF-36 and objectively evaluated at the same interval with basic stride analysis and the 6-minute walk test. Correlation analysis of the subjective and objective data (both perioperative improvement and postoperative absolute scores) yielded Pearson coefficients of r = 0.05–0.81. This work demonstrates a sound statistical relationship between walking ability and the functional aspects of the WOMAC and the SF-36, supporting the use of these instruments in assessing the functional outcome after THA.
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An end-result analysis is presented of thirty-nine mold arthroplasties performed at the Massachusetts General Hospital between 1945 and 1965 in thirty-eight consecutive private patients for arthritis of the hip following fractures of the acetabulum or dislocations of the hip. Of the nineteen unilateral cases in the second half of the series, sixteen were rated good or excellent. Results in the second half of the series were significantly better statistically than those in the first half of the series. Possible reasons for this improvement are discussed. No significant deterioration occurred with the passage of time. Among the thirty-nine hips, three revisions were required. One patient had postoperative sepsis after arthroplasty. Four patients who had had intra-articular sepsis prior to arthroplasty showed no evidence of sepsis postoperatively. Factors influencing the choice between hip fusion and hip arthroplasty in these cases are presented. A new system for rating hip function is proposed and is compared with the systems of Larson and Shepherd.
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Evaluation of functional capacity is important when defining needs for therapy as also is the evaluation of rehabilitation effects in patients with rheumatic diseases. The aim of this overview is to describe the development and initial evaluation of the Index of Muscle Function (IMF), a battery of functional performance tests focusing mainly on the muscle function of the lower extremities. In addition, new data concerning reliability and validity are presented. The IMF total index can be divided into four separate areas: pre-tests of general functioning, muscle strength, muscular endurance and balance/coordination. Results indicate that the IMF is simple to use both at the clinic and at the patient's home, that it possesses sufficient properties with respect to reliability and validity, that it discriminates between different groups, and that it detects changes within rehabilitation in patients with rheumatoid arthritis.
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Evaluation of functional capacity is important when defining needs for therapy as also is the evaluation of rehabilitation effects in patients with rheumatic diseases. The aim of this overview is to describe the development and initial evaluation of the Index of Muscle Function (IMF), a battery of functional performance tests focusing mainly on the muscle function of the lower extremities. In addition, new data concerning reliability and validity are presented. The IMF total index can be divided into four separate areas: pre-tests of general functioning, muscle strength, muscular endurance and balance/coordination. Results indicate that the IMF is simple to use both at the clinic and at the patient's home, that it possesses sufficient properties with respect to reliability and validity, that it discriminates between different groups, and that it detects changes within rehabilitation in patients with rheumatoid arthritis.
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To develop a clinical risk prediction tool to identify patients most likely to experience long-term clinically meaningful functional improvement following total hip arthroplasty (THA). We studied 282 patients from 2 health districts in England (Portsmouth and North Staffordshire) who were ≥45 years of age and undergoing THA for primary osteoarthritis. Baseline data on age, sex, comorbidity, body mass index (BMI), functional status (Short Form 36 [SF-36]), and preoperative radiographic severity were collected by interview and examination. The outcome was a clinically significant (30-point) improvement in SF-36 physical function score assessed ~8 years after THA. Logistic regression modeling was used to identify predictors of functional improvement. Improvement in physical function was less likely in patients with better preoperative functioning (odds ratio [OR] 0.73 [95% confidence interval (95% CI) 0.60, 0.89]), older people (OR 0.94 [95% CI 0.90, 0.98]), women (OR 0.37 [95% CI 0.19, 0.72]), those with a previous hip injury (OR 0.14 [95% CI 0.03, 0.74]), and those with a greater number of painful joint sites (OR 0.61 [95% CI 0.46, 0.80]). Patients with worse radiographic grades were most likely to improve (OR 2.15 [95% CI 1.17, 3.93]). We found no influence of BMI or patient comorbidity on functional outcome. Predictors of good outcomes were the same as those of bad outcomes, acting in the opposite direction. A clinical risk prediction tool was developed to identify patients who are most likely to receive functional improvement following THA. This prediction tool has the potential to inform health care professionals and patients about functional improvement following THA (as distinct from driving rationing or commissioning decisions regarding who should have surgery); it requires introduction into clinical practice under research conditions to investigate its impact on decisions made by patients and clinicians.