Aman Singh

National Institute of Technology Rourkela | NITR · Department of Mining Engineering (MN)

Solvent-free reductive amination of aldehydes and ketones with aliphatic and aromatic amines in high-to-excellent yields has been achieved with sub-stoichiometric trimethyl borate as promoter and ammonia borane as reductant.

The strength of artificial neural networks (ANN) for prediction of output welding process parameters for given input welding process parameters is shown in this work. Some important concepts of ANN are discussed. A model for weld bead geometry relating to input process parameters is made with the help of a computer program in C++. Feed-forward back...

A comparative study of various techniques which can be used for summarization of Videos i.e. Video to Video conversion is presented along with respective architecture, results, strengths and shortcomings. In all approaches, a lengthy video is converted into a shorter video which aims to capture all important events that are present in the original...

Oxy-acetylene welding and cutting processes are popular, easily available and one of the cheapest methods of working with metals. Welding process is used by many construction and manufacturing firms. There are several welding processes to join materials to achieve the desired purpose. Gas welding is one of the cheapest processes of welding and gene...

Friction stir welding is a solid state joining process that welds two or more similar or dissimilar materials having different melting points through a blend of heat created by friction and mechanical mixing of the materials in the locale of the joint. Different alloys having elements like aluminium, magnesium etc and hard materials like steels are...

The proper implementation of any welding process depends upon its input process parameters. The principle aim of this review research paper is to make analysis of various parameters of submerged arc welding process as examined by several researchers for optimum output values. These parameters are welding current, welding speed, welding current, wir...

If a high quality of welding joint in thick metal is required, submerged arc welding process is preferably used. There are several welding input process parameters which influence the quality of the weld. Some important input process parameters in the case of submerged arc welding process are welding current, welding voltage, wire feed and carriage...

Present work aim to study the influence of feed rate, cutting speed and depth of cut on MRR and surface roughness of AISI 316 stainless steel during turning process. The tool used in the study was a generally used uncoated carbide tool. The experimental trial was planned by using full factorial method of design of experiments. Further the ANOVA ana...

Acyldepsipeptides are a unique class of antibiotics that act via allosterically dysregulated activation of the bacterial caseinolytic protease (ClpP). The ability of ClpP activators to kill non-growing bacteria represents a new opportunity to combat deep-seated biofilm infections. However, the acyl depsipeptide scaffold is subject to rapid metaboli...

Background: India is witnessing a rapid health transition with a rising burden of Non-Communicable Diseases (NCDs) which account for around 5.8 million or 61% of all deaths annually. The Government of India has launched the world’s largest government-funded health Programme “Ayushman Bharat” to strengthen comprehensive primary health care, reduce o...

The rapid digital transformation without security considerations has resulted in the rise of global-scale cyberattacks. The first line of defense against these attacks are Network Intrusion Detection Systems (NIDS). Once deployed, however, these systems work as blackboxes with a high rate of false positives with no measurable effectiveness. There i...

REV1 is a DNA damage tolerance protein and encodes two ubiquitin-binding motifs (UBM1 and UBM2) that are essential for REV1 functions in cell survival under DNA-damaging stress. Here we report the first solution and X-ray crystal structures of REV1 UBM2 and its complex with ubiquitin, respectively. Furthermore, we have identified the first small-mo...

Antibiotics with novel bactericidal mechanisms of action are urgently needed. The antibiotic acyldepsipeptide 4 (ADEP4) activates the ClpP protease and causes cells to self-digest. The effects of ADEP4 and ClpP activation have not been sufficiently characterized for the enterococci, which are important pathogens known for high levels of acquired an...

The paper presents an analytical study of noise in Van der Pol oscillator output subjected to an external force noise assumed to be characterized by delta function (white noise). The external fluctuations are assumed to be small in comparison to the average response of the noise free system. The autocorrelation function and power spectrum are calcu...

Injection of fluids continuously into the reservoir at higher flow rates can create channels for preferential movement of fluids. Zones of higher permeability, leading to higher injectivity in selective zones, can also exist because of various lithological conditions and rock structures comprising of naturally occurring fractures or fissures (Vasqu...

The constitutive androstane receptor (CAR) and pregnane X receptor (PXR) are xenobiotic sensors that regulate the expression of drug-metabolizing enzymes and efflux transporters. CAR activation promotes drug elimination, thereby reducing therapeutic effectiveness, or causes adverse drug effects via toxic metabolites. CAR inhibitors could be used to...

In an effort to develop new fluoroquinolones, we synthesized eight compounds and tested them against a panel of bacteria. The design of these compounds was guided by the introduction of the isothiazoloquinolone motif. The three most active compounds in this series, 8-10, demonstrated good antibacterial activity against methicillin-sensitive Staphyl...

For decades, the oil and gas exploration industry evaluated assets and screened them for future development based on certain characteristic requirements/pay cutoffs such as shale percentage, water saturation, and porosity. Reservoirs that did not meet these specific requirements were considered uneconomical and not considered for further developmen...

Alcohol consumption exacerbates liver injury in chronic hepatitis C, and enhanced mitochondrial oxidative stress is one possible mechanism. The aim of this study was to determine whether hepatitis C virus core protein and alcohol-inducible cytochrome P450 2E1 contribute to reactive oxygen species production and cytotoxicity in human hepatoma cells....