Alexandra Michelon

Alexandra Michelon
Universidade Estadual do Oeste do Paraná | UNIOESTE · Centro de Ciências Médicas e Farmacêuticas

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3
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Publications

Publications (3)
Article
Full-text available
Besides being scarce, the drugs available for treating cutaneous leishmaniasis have many adverse effects. Ozone is an option to enhance the standard treatment due to the wound-healing activity reported in the literature. In this study, we evaluated the efficiency of ozonated sunflower oil as an adjuvant in treating cutaneous lesions caused by Leish...
Article
Full-text available
Aims: This study aimed to characterize and evaluate leishmanicidal and trypanocidal action as well as cytotoxicity on macrophages and antioxidant ability of extracts, obtained by supercritical CO2 and ultrasound-assisted extractions of Uvaia (Eugenia pyriformis) leaves. Methods: Leaves from E. pyriformis were submitted to supercritical CO2 (E1)...
Article
Full-text available
Extratos das sementes de Eugenia pyriformis têm mostrado uma promissora atividade contra Leishmania (parasita atualmente negligenciado) em ensaios in vitro, assim, estabelecer a sua relação com o sistema imune mamífero é importante para futuros experimentos in vivo. Este trabalho propõe o uso dos extratos de folhas de E. pyriformis, obtidos por ext...

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