Alaa Labeeb

Menoufia University · Department of Rheumatology

ObjectivesTo assess the level of awareness among primary health care physicians toward musculoskeletal complications among type2 diabetic patients in Gharbia Governorate, Egypt.BackgroundDiabetes mellitus is a major public health problem worldwide. Most diabetic patients will develop functional disabilities owing to multiple factors, including musc...

Abstract: Background: Worldwide, leflunomide is a commonly used Disease-Modifying Anti-Rheumatic Drugs (DMARDs). It can be used as a monotherapy or in combination with other DMARDs to inhibit the production of inflammatory cells and accordingly reduce inflammation. Objectives: CLEAR is a multi-centric study that aims to assess the clinical efficacy...

Key words: CTLA-4, IL-1β, polymorphism, SLE Background: SLE is an autoimmune disease with complex etiology. Genetic aberrations disrupting the immune regulatory mechanisms may initiate autoimmune disease development. As CTLA-4 is a negative regulator of T-cell immune response and IL-1β is a potential pro-inflammatory cytokine, their allelic polymor...

Background Around 50% of women receiving Aromatase Inhibitors (AIs) develop musculoskeletal symptoms which may become severe causing interruption of treatment. Patients with AI-induced arthralgia had higher rates of joint effusions and fluid in the tendons, so use of diuretics may be helpful. Methods This prospective phase II study was conducted i...

Aim of the work: To evaluate three subtypes of CD4⁺Foxp3⁺ T cells, interleukin-35 (IL-35) and IL-10 in systemic lupus eryhtematosus (SLE) patients and study their relation to disease activity. Patients and methods: Fifty SLE patients were included and divided according to the SLE disease activity index (SLEDAI) into 2 equal groups with activity or...

Aim of the study: To investigate the effects of preoperative physical and respiratory therapy on pulmonary functions and complications after elective laparoscopic upper abdominal surgery in obese patients. Methodology: Patients were randomly assigned to receive respiratory and general exercise for 2 weeks before operation (group I; n = 26) two phys...

Background The majority of rheumatoid arthritis (RA) patients develop symptoms related to their foot or ankle.¹ Extraarticular manifestations occur in 10–20% of patients. Symptoms of neuropathy may be overlooked or overestimated in case of severe joint disease, restriction, pain and deformities.² Objectives This study aimed to evaluate neuropathic...

Acupuncture or dry needling, in clinical practice have been used successfully in the treatment of pain associated with muscle tone alterations. However a possible direct effect on muscle tone has never been clearly separated from its analgesic action. The H-reflex is a recognised neurophysiological index of the excitability of spinal motor neuron p...

Aim This study aimed to evaluate neuropathic foot pain in patients with rheumatoid arthritis (RA) using electrophysiological studies and musculoskeletal ultrasound (MSUS) to address the association between these findings and disease activity. Evaluation of the usefulness of this combination was undertaken. Design The present study was designed as a...

Objective The aim of our study is to determine serum 25(OH)-vitamin D level in patients with fibromyalgia syndrome and its relation to pain. Patients and methods Fifty-three women with fibromyalgia syndrome diagnosed according to the American College of Rheumatology 1990 fibromyalgia diagnostic criteria and 50 age-matched healthy women as a contro...

Objective The aim of this study was to ascertain the existence of contralateral painful muscle areas mirroring phantom pain and to evaluate the short-term effects of anaesthetics versus saline, injected contralaterally to control phantom and phantom limb pain. Design This was a double-blinded cross-over study. Participants This study included eight...

The rehabilitation of the amputated patient is based on a coordinated sequence of diagnostic, prognostic and therapeutic procedures carried out by an interdisciplinary rehabilitation team, that works globally on all patient problems. The objectives of the different phases of the rehabilitation treatment were reviewed. Due to their relevance in cond...

This paper reviewed the various hypotheses on phantom limb and phantom limb pain as well as all the related rehabilitation techniques to control these symptoms. The uncertainty in their pathophysiology strongly affects all the rehabilitation approaches so far used, as no single parameter has been found to predict or control phantom limb pain as wel...

To ascertain the existence of contralateral painful muscle areas mirroring phantom pain and to evaluate the short-term effects of anaesthetic vs saline, injected contra notlaterally to control phantom and phantom limb pain. Double-blinded cross-over study. Inpatients; rehabilitation institute. Eight lower limb amputees with phantom limb pain in the...