• Home
  • Akhilesh Kumar Singh
Akhilesh Kumar Singh

Akhilesh Kumar Singh
Mahatma Gandhi Central University, Motihari, Bihar · Biotechnology

M.Sc.-Biotechnology (IIT-Roorkee); M.Tech.-Agricultural Biotechnology (IIT-Kharagpur) & Ph.D.-PHA Bioplastic (IIT-Kharagpur); CSIR-JRF(NET); ICAR-NET & GATE

About

120
Publications
45,813
Reads
How we measure 'reads'
A 'read' is counted each time someone views a publication summary (such as the title, abstract, and list of authors), clicks on a figure, or views or downloads the full-text. Learn more
2,339
Citations
Introduction
Dr. Singh is interdisciplinary trained applied microbiologist/ biotechnologist/ nanobiotechnologist and working as Assistant Professor in the Department of Biotech and Genome, Mahatma Gandhi Central University, Motihari, Bihar, India. Recipient of ICAR-NET, GATE and CSIR-JRF/SRF Fellowships, India; Editorial Board Member of Indo Global Journal of Pharmaceutical Sciences; Reviewer of Journals: Springer (APPL. BIOCHEM. BIOTECHNOL., etc.) Elsevier (ALGAL RES., J. CLEAN. PROD., etc.), Wiley (BIOTECHNOL. PROG), etc. Research areas: Microbial/Environmental Biotechnology, PHAs/Nanoparticles & Biofuels. Techniques: Biochemical separation techniques, GC-MS Spectrometry, HPLC, Statistical Modelling (RSM), etc.
Additional affiliations
October 2019 - March 2020
Mahatma Gandhi Central University, Motihari, Bihar
Position
  • Professor (Assistant)
Description
  • Role: Teaching & Research with other Academic and Administrative responsibilities
September 2014 - October 2019
Amity University Uttar Pradesh Lucknow India
Position
  • Professor (Assistant)
Description
  • Nature of work: Teaching/ Research/ Other academic activities
January 2013 - August 2014
Amity University Uttar Pradesh Lucknow Campus India
Position
  • Professor (Associate)
Description
  • Nature of work: Teaching/ Research/ Other academic activities

Publications

Publications (120)
Article
Full-text available
The response of Chlorella vulgaris to copper exposure was investigated under laboratory batch culture conditions. Increased toxicity of Cu with respect to photosynthetic carbon fixation, O(2) evolution, chlorophyll fluorescence, and oxidative burst was observed for N-NH(4)(+)-grown cultures. The addition of sodium nitroprusside, a nitric oxide (NO)...
Article
Full-text available
The present study focused on the green and sustainable synthesis of zinc oxide (ZnO) quantum dots (QDs) using zinc acetate (precursor) and Eclipta alba leaf extract as a reducing agent. The synthesis of ZnO QDs was monitored by ultraviolet-visible absorption spectroscopy at wavelength (λmax) 324 nm. The optimal synthesis of ZnO QDs was recorded at...
Article
Full-text available
An eco-friendly approach was developed for the fabrication of nickel (Ni)/nickel hydroxide (Ni(OH)2) nanoparticles (NPs) from nickel sulfate as a precursor using phytochemically rich Asparagus racemosus Linn. leaf extract. The impacts of pH, temperature, leaf extract, nickel sulfate concentrations, and incubation period on NP particle size and stab...
Article
Full-text available
The increasing utilization of nanoparticles (NPs) in agricultural practices has led to a surge in demand for nano-based products. Herein, we investigate the dose-dependent impacts of nickel hydroxide (Ni(OH) 2)/nickel (Ni) NPs, synthesized using Asparagus racemosus Linn. leaf extract, on the seed germination and growth of Vigna radiata (Linn.) Wilc...
Article
Full-text available
A simple green chemistry route has been developed for the synthesis of copper (Cu) quantum dots (QDs) from copper sulfate using leaf extract of Mangifera indica (L.) with assessment of their catalytic, antibacterial and antioxidant activities. The impact of quantities of leaf extract, concentrations of copper sulfate, incubation temperature, pH and...
Chapter
Organic waste management is an essential aspect of recycling resources and can contribute to mitigating climate change. The proper management of solid waste has become an increasingly alarming environmental concern in the current scenario due to the growth of population, rapid urbanization, and industrial development. Composting and vermitechnology...
Article
In biorefining, biomass is processed sustainably to produce multiple high-value products. The biorefinery concept has been acknowledged as the most promising tactic for creating a biomass-based business/ industry. Biomass from microalgae includes a variety of beneficial bioactive elements like pigments, proteins, polyunsaturated fatty acids, and po...
Article
Fructooligosaccharides (FOS) are essential components found in various vegetal biomass sources, including foods, agricultural residues, fruits, and vegetable waste. Comprising 3 to 10 monosaccharide units, they resist digestion in the human gastrointestinal tract and are recognized as prebiotics, fostering the proliferation of beneficial bacteria i...
Article
Full-text available
Recent insights have unveiled exciting opportunities to explore the intricate interplay among bacterial biofilms, tumor cells, and the immune system, thus offering new perspectives in cancer biology. The implications of bacterial biofilms in this context are remarkably multifaceted. Biofilms can promote tumor growth and invasiveness by inducing chr...
Article
Full-text available
Ammonia, a vital player in the global economy, propels economic growth through its key role in fertilizer production, boosting agricultural output significantly. While traditional methods dominate its production, recent efforts focus on sustainable pathways like green ammonia, produced using renewable energy. This colourless gas, beyond agricult...
Chapter
Carbon nanomaterials (CNs) possess unique physical, chemical, and physiological properties that make them highly valuable as carriers for biologically important molecules. However, their use is limited due to potential health and environmental effects. Nevertheless, CNs exhibit great potential in drug delivery owing to their high biocompatibility a...
Article
Full-text available
Excessive consumption of antibiotics like gentamicin (GEN) can lead to hostile effects as antibiotic resistance. Therefore, the detection is important for which, reduced graphene oxide-Gadolinium oxide nanocomposite (rGO@Gd2O3 NC) was composed through co-precipitation method for the detection of GEN. The structural, morphological and functional gro...
Chapter
The utilization of biostimulants is a cutting-edge technique that shows great promise for addressing food security issues. Biostimulants are considered solutions to the restrictions of old-fashioned techniques of crop production and to overcome the challenges of climate change issues. Protein hydrolysates are considered biostimulants that offer gre...
Article
Full-text available
New materials’ synthesis and utilization have shown many critical challenges in healthcare and other industrial sectors as most of these materials are directly or indirectly developed from fossil fuel resources. Environmental regulations and sustainability concepts have promoted the use of natural compounds with unique structures and properties tha...
Article
Full-text available
Importance of nanotechnology may be seen by penetration of its application in diverse areas including the food sector. With investigations and advancements in nanotechnology, based on feedback from these diverse areas, ease, and efficacy are also increasing. The food sector may use nanotechnology to encapsulate smart foods for increased health, wel...
Article
Full-text available
Food waste is a significant emitter of greenhouse gases (mostly methane) that causes environmental devastation. Further, nearly onethird of produced food goes to wastage during the supply chain and harvesting process. These can contribute to a yearly loss of US$ 1 trillion. Considering these, there is a great concern all over the world regarding su...
Article
Full-text available
Hydrogen, a form of energy that is both clean and renewable, is now being researched and developed as a potential source of alternative energy. There are many different kinds of microbial systems that have the potential to be utilised in the manufacturing of biohydrogen. Thermophiles are found as potential producers of hydrogen, at a high rate, in...
Chapter
Full-text available
Most of biological processes like fermentation are completed via cultivation of suitable microbial system that is specific and capable of producing the different type of metabolites (primary/ secondary). These processes require the specific media for cultivation of specificand over-producer microbial system such as bacterial, fungal and cyanobacter...
Chapter
Full-text available
Microbial biomass synthesis is a very important process via different types of microbial cells system and it is responsible for yield and titer of any metabolites and also others nutrient contents in their biomass synthesis. Microbial biomass is natural and laboratory induced processes and is affected by culture conditions, nutrient availability, b...
Chapter
Full-text available
Metabolites are organic compounds that are required for daily life of human. These compounds are normally synthesized by different types of microbial cells (bacteria, fungal, cyanobacterial or yeast cells), plant and animal cells that utilized the different metabolic pathways via consuming of different types of carbon and nitrogen sources. In ancie...
Article
Full-text available
In the current scenario in many cities, huge quantities of biowaste solid matter are generated, making it a big challenge to keep our cities smart/clean without creating health issues. The second challenge is to mitigate solid biowastes from municipalities, and it needs systematic valorization/conversion approaches to transform/generate them into c...
Article
Full-text available
The global energy generation market immensely depends on fossil fuels which balances our survival on this planet. Energy can be called as the “master element” for our daily needs, starting from household power supply, agricultural purpose, automobile and transportation, industrial workload to economic and research domains. Fuel switching initiative...
Article
Full-text available
The valorisation of food and fruit wastes has the potential for the production of sustainableenergy and biochemicals. Approximately 70% of the weight of the original jackfruit (Artocarpusheterophyllus L.) fruit is lost during its processing as waste in the form of peeled skin and core, both ofwhich have not been utilized and, thus these contribute...
Chapter
Alcohol dehydrogenases (ADHs) are oxidoreductases that break down alcohol. They catalyze the oxidation of a variety of substrates, which is followed by the reduction of appropriate electron acceptors, most commonly NAD+/NADP+, FAD or FMN. Alternatively, one or more hydride ions are transferred from substrates to oxidizing cofactors/electron accepto...
Article
Glycoconjugates are the ubiquitous components of mammalian cells, mainly synthesized by covalent bonds of carbohydrates to other biomolecules such as proteins and lipids, with a wide range of potential applications in novel vaccines, therapeutic peptides and antibodies (Ab). Considering the emerging developments in glycoscience, renewable productio...
Article
Full-text available
Since the impending warning of fossil fuel inadequacy, researchers' focus has shifted to alternative fuel generation. This resulted in the use of a wide variety of renewable biomass sources for making biofuels. Biofuels made from biomass are seen as the most promising long-term strategy for addressing issues associated with conventional energy sour...
Preprint
Full-text available
Valorization of food and fruit wastes has the potential for the production of sustainable energy and biochemicals. Approximately 70% of the weight of the original jackfruit (Artocarpus heterophyllus L.) fruit is lost during processing as waste in the form of peeled skin and core, both of which have not been utilized and, thus contribute to disposal...
Chapter
The ABCE classes of homeotic genes partially describe the hereditary connections that control the aspects of floral organ commencement, growth, and design, but little is understood on how these genes’ abilities were transformed into various cellular growth and morphogenesis that are responsible for the establishment of flower organs with specific s...
Chapter
Auxins are a class of compounds showing lower molecular weight with growth-promoting properties. Auxin, which is mostly characterized by indole-3-acetic acid (IAA), is a phytohormone that regulates plant development and growth. Despite the fact that IAA was the first plant hormone discovered, the biosynthesis pathway has remained a mystery at the g...
Chapter
Plants are usually encountered diverse stressors like intense temperature, water shortages, flooding, and salinity. These stressors ultimately result in physiological disturbances, enzyme inactivation, and changes in cellular redox homeostasis. These in turn hamper plant survival as well as crop productivity. However, plants have been found to evol...
Article
Full-text available
RNA viruses have been the most destructive due to their transmissibility and lack of control measures. Developments of vaccines for RNA viruses are very tough or almost impossible as viruses are highly mutable. For the last few decades, most of the epidemic and pandemic viral diseases have wreaked huge devastation with innumerable fatalities. To co...
Article
Full-text available
Worldwide, a huge production of agro-industrial wastes is observed every year in the milling, brewing, agricultural, and food industries. Biochemical and bioactive substances can be produced from these agricultural wastes. Pineapple by-products, which consist of the peeled skin, core, crown end, etc., account for 60% of the weight of pineapple frui...
Chapter
Toxic and poisonous effect of plants has been known since ages. Hemlock, sometimes referred as poison hemlock, is a nitrophilic plant of the Apiaceae (originally Umbelliferae) family. It is native to Europe, particularly the Mediterranean, and is well known for its severe toxicity to people and domestic animals. Poison had such a significant impact...
Chapter
Full-text available
An enhancement in crop productivity is one of the crucial requirements in order to circumvent the increasing food demands globally. Crop productivity may be improved via plant nanobiotechnology that involve the integration of plant biotechnology with nanotechnology. The plant nanobiotechnology exploits the nanoparticles (NPs) for boosting the agric...
Chapter
White biotechnology is a multidisciplinary branch of biotechnology dedicated to generating renewable fuels, chemicals, food and feed, enzymes, and other biobased products at the industrial level employing bioprocesses. The transition from lignocellulosic biomass (LCB) into a vast diversification of valuable chemicals as well as products such as org...
Chapter
The greater adaptability of the Parthenium hysterophorus L. over other weeds facilitates its growth and development under different ecological conditions, including agricultural fields. This toxic weed causes enormous loss to biodiversity, agriculture productivity, cattle health, and others. The physiochemical approaches that have been employed for...
Chapter
Full-text available
The greater adaptability of the Parthenium hysterophorus L. over other weeds facilitates its growth and development under different ecological conditions, including agricultural fields. This toxic weed causes enormous loss to biodiversity, agriculture productivity, cattle health, and others. The physiochemical approaches that have been employed for...
Chapter
Full-text available
Carotenoids are pigments having a proven role as food colorants, antioxidants, health-promoting substances, food additives, feed additives, vitamins, pharmaceuticals, etc. After experiencing the hazard of synthetic entities in human life, people are again trying to “go natural.” Being natural and part of a healthy ecosystem, microalgae may have imm...
Chapter
Full-text available
The utmost normally abiotic stress–triggered expression in plants involves the transcription factors activating stress responsive genes, thereby causing the formation of reactive oxygen species (ROS). ROS signaling pathways along with plant hormones act as key mediators culminating into activation of downstream metabolic routes and alterations at t...
Chapter
Full-text available
High salt concentration in arable soil/soil salinization poses an increasing agricultural problem all over the world. Such salt accrual is resulting from the sea water mixing with irrigation supply and naturally high content of salts in water used for agricultural irrigation. Further, concerning plants, the stress generated by salt salinization of...
Chapter
Full-text available
Being static, the plants are exposed to different kinds of external factors. Many external factors negatively influence the plant metabolism and physiology which cause stress. Stress is such a condition mainly created by external factors in which metabolism of cell is adversely regulated, so that normal functioning of the cell is disrupted. These e...
Chapter
Plants with therapeutic and medicinal characteristics have been used by mankind since ancient times. However, the introduction and use of contemporary synthetic medicines by the local people has resulted in the loss of traditional knowledge. As a result, it is essential to chronicle the knowledge of plant uses for the treatment of various diseases...
Article
Full-text available
In the current period, there is a high demand for the production of liquid fuel which is used for transport purposes all over the world. Therefore, the conversion of methane to methanol fuel is reported as an alternative option for natural gas. Some approaches such as the two-step syngas process, direct single step, and bacterial agent catalyzed re...
Article
Full-text available
Agricultural residues play a pivotal role in meeting the growing energy and bulk chemicals demand and food security of society. There is global concern about the utilization of fossil-based fuels and chemicals which create serious environmental problems. Biobased sustainable fuels can afford energy and fuels for future generations. Agro-industrial...
Article
Full-text available
The reduction of greenhouse gases in the automobile and industrial sectors has been a focus of global concern due to their adverse effects on the environment. This has led to a search for clean, green, and sustainable biobased energy sources. Green energy sources have a positive effect on the environment. Lignocellulosic waste biomass from various...
Chapter
Full-text available
Various abiotic stress conditions are one of the main constraints to crop production and food security throughout the globe. In this connection, numerous research evidence supports the role of hydrogen sulfide in higher plants as a gaseous molecule accountable for stress alleviation. Exposure of plants to hydrogen sulfide seems to afford supplement...
Chapter
Full-text available
Being static, both lower and higher plants are subjected to diverse kinds of stresses as a result of biotic/abiotic components. These adverse conditions upset plant growth and development. The tolerance response of the plant towards the aforesaid stress environments is attributed as a result of resilience mechanisms. Apart from proline as well as s...
Chapter
Full-text available
Globally, an unprecedented transformation in climatic conditions has substantially influenced the plants ability to adapt to changing climatic conditions. The alteration in the climatic environments has been caused owing to the combined outcome of increased population, urbanization, and globalization. The chemical-based fertilizers as well as pesti...
Chapter
Full-text available
In the era of rapid industrialization, there is increasing global concerns pertaining to anthropogenic activities mediated massive enhancement in atmospheric greenhouse gases like carbon dioxide, etc., thereby triggering global warming phenomenon. The global warming mediated climate change has been found to impose long-lasting detrimental impact on...
Book
Full-text available
This book provides up-to-date knowledge of the promising field of Nanobiotechnology with emphasis on the mitigation approaches to combat plant abiotic stress factors, including drought, salinity, waterlog, temperature extremes, mineral nutrients, and heavy metals. These factors adversely affect the growth as well as yield of crop plants worldwide,...
Chapter
Full-text available
In the epoch of global warming with climate change, various unprecedented challenges were encountered by the agricultural systems globally. The same was reflected in the response by the agricultural scientists and practitioners to combat the challenges. Many findings at the level of lab and improvising practices at the level of farm have influenced...
Chapter
Full-text available
Abiotic and biotic stresses are significantly affects the plant growth, thereby limiting agricultural productivity of crops. Agricultural plants/crops should be able to cope-up with both biotic and abiotic stresses by their innate biological mechanisms, failing which affect their growth, development and productivity. As per FAO, there is a need to...
Chapter
Full-text available
Nanoparticles application in plant science requires technological and theoretical amalgamation governed by features of nanoparticles as well as their molecular and physiological responses in each plant. Agriculture is the most important sector for human wellbeing as it provides resources for food and feed industries. Factors contributing to abiotic...
Chapter
Full-text available
Drought is one of the acute problems for crops with respect to crop productivity as per the concerned present scenario. Nowadays, this problem is gaining more attention due to the diverse and costly effects at economic levels. For a crop to adapt to drought conditions, several changes must occur in it to survive. High proline and glycine betaine co...
Article
Full-text available
Nanomedicine has emerged as a lucrative option, which attracts the attention of scientific and industrial stalwarts for its enormous potential and new business opportunities in the health sector. Since it encompasses physical, chemical, and biological interventions used for the transformation of bulk materials into nanomaterials (NMs) with particle...
Chapter
Full-text available
Presently, fossil fuels are consistent resource of energy for running ships, aircraft, trucks as well as automobiles that are key modes of transportation toward the efficient functioning of the society. However, rising greenhouse gas emissions and shrinking fossil fuel reserves lead to introduction of biofuels that offers many advantages to human r...
Chapter
Full-text available
Biogas is produced from organic substrates by anaerobic digestion (AD) process. Methanogenic microorganisms anaerobically degrade the organic materials primarily into (50–75%), CO2 (25–50%), N2 (0–10%), H2 (0–1%), H2S (0.1–0.5%), and O2 (0–0.5%). AD process could be performed by mesophilic or thermophilic microorganisms. Like natural gas, biogas ca...
Article
Full-text available
Cycles of light/ dark play a vital role in physiology/growth of plants by triggering different metabolic responses. Plants not only sense the commencement of dark stress environment but also utilize it for coordinating growth phenomenon. Likewise, copper as a vital micronutrient is needed by plants for mitochondrial respiration, antioxidant activit...
Article
Full-text available
Cycles of light/ dark play a vital role in physiology/growth of plants by triggering different metabolic responses. Plants not only sense the commencement of dark stress environment but also utilize it for coordinating growth phenomenon. Likewise, copper as a vital micronutrient is needed by plants for mitochondrial respiration, antioxidant activit...
Chapter
Full-text available
Adulteration is a term, where a food product fails to meet the legal standards. One form of adulteration is an addition of another substance to a food item in order to increase the quantity of the food item in raw form or prepared form, which may result in the loss of actual quality of food item. These substances may be either available food items...
Thesis
Full-text available
Traditional NPs fabrication approaches are non-environmentally friendly and the process of NPs fabrication involve substantial utilization of energy for maintaining the temperature as well as high pressure. The present investigation demonstrated an economical, quick, simple, and green synthetic protocol for the high bio-induced transformation of Cu...
Chapter
Full-text available
Soil fulfills a wide-range of ecological services such as a platform towards biomass generation, a filter/buffer for water, main store of carbon, important source of nutrients in our foodstuff as well as medicines like antibiotic and so on. However, currently, soil pollution has become one of the alarming issues in most of the developed/developing co...
Article
Full-text available
In present investigation, the selective removal of Al from the quasi-lattice sites of quasicrystalline alloy surface has been examined in order to produce the nano-particles of metal/metal oxides within the micro-porous network. Al was selectively etched from both the as-cast as well as annealed Al63Cu25Fe12 quasicrystalline alloys through the trea...
Article
Full-text available
Human malaria is a pathogenic disease mainly caused by Plasmodium falciparum, which was responsible for about 405,000 deaths globally in the year 2018. To date, several vaccine candidates have been evaluated for prevention, which failed to produce optimal output at various preclinical/clinical stages. This study is based on designing of polypeptide...
Chapter
Full-text available
The present trend of fabricating non-degradable conventional plastics, i.e., petroleum-based plastics from ever-diminishing and environmentally unfriendly fossil fuel sources is unsustainable. Therefore, substituting petroleum-based plastics with biodegradable plastics like polyhydroxyalkanoates (PHAs) can potentially diminish the release of greenh...
Article
Full-text available
Visceral leishmaniasis (VL) caused by Leishmania donovani is a fatal parasitic disease affecting primarily the poor population in endemic countries. Increasing number of deaths as well as resistant to existing drugs necessitates the development of an effective vaccine for successful treatment of VL. The present study employed a combinatorial approa...
Article
Full-text available
The emergence of lignocellulosic biorefineries (LBRs) over the past few decades has shown tremendous potential for the development of sustainable renewable resources. Lignocellulosic biorefineries not only meet energy needs but also mitigate environmental problems by replacing conventional petroleum sources. Round the year availability of lignocell...
Chapter
Full-text available
Drought stress conditions are imposing a foremost restraint to crop production as a result food security is becoming a most apprehension worldwide. The circumstances have intensified because of the extreme and swift variations in worldwide climatic conditions. Drought is certainly one of the utmost imperative stress situation causing vast impressio...
Chapter
Full-text available
Over the last decades, the exploitation of cutting-edge nanotechnology in forestry sector is in its infancy stage and, therefore presently, much efforts have been devoted in the same direction towards the development of nano-sized forest/fibre-based products, improved UV/water/pest resistant wood, etc. In forestry sector/industry, the nanotechnolog...
Article
Full-text available
The emergence of lignocellulosic biorefineries (LBRs) over the past few decades has shown tremendous potential for the development of sustainable renewable resources. Lignocellulosic biorefineries not only meet energy needs but also mitigate environmental problems by replacing conventional petroleum sources. Round the year availability of lignocell...
Chapter
Full-text available
Globally, nanotechnology has been materialized as a novel field of modern science in recent years owing to its exceptional properties with widespread applications. This field acts as an innovative platform for the tailoring of materials like metals at the atomic level so as to achieve exceptionally small size as well as large surface to volume rati...
Chapter
Full-text available
Water is indispensable element that is needed for survival of life on earth. However, increasing competition toward water sources as a result of agricultural, industrial, as well as domestic users has resulted into sharp increase in stress on aquatic as well as wetland ecosystems. In addition, prominent climatic changes and natural disasters along...
Chapter
Full-text available
Abiotic stresses are very important constraints that adversely affect the production of a crop. Plants are sessile organisms that are exposed to environmental variations and various stress factors throughout their life. Plants handle these stress conditions and develop various mechanisms to counteract adverse conditions. Nanotechnology is an emergi...
Chapter
Full-text available
The applicability of biomolecules can be considerably increased by combining them with “green solvents,” i.e., ionic liquids (ILs) instead of employing the usual organic solvents or water. In the present decade, ILs have been exploited for a number of biotechnological uses like solubilization as well as stabilization of biomolecules (DNA, protein/e...
Article
Full-text available
Visceral leishmaniasis (VL) is a dreadful protozoan disease caused by Leishmania donovani that severely affects huge populations in tropical and subtropical regions. The present study reports an unbiased genome based screening of 4 potent vaccine antigens against 8023 L. donovani proteins by following the criteria of presence of signal peptides, GP...
Article
Full-text available
Climate change is the one of the most emerging problem of today's world. It is the most potent threat to the existence of mankind. These sudden abrupt changes in the climate are affecting all the crops to a great extent. High concentrations of CO₂ are one of the leading reasons contributing to climate change due to the increasing level of greenhous...
Article
Full-text available
Biopolymeric polyhydroxyalkanoates (PHAs) are fabricated and accumulated by microbes under unbalanced growth conditions, primarily by diverse genera of bacteria. Over the last two decades, microbially engineered PHAs gained substantial interest worldwide owing to their promising wide-range uses in biomedical field as biopolymeric biomaterials. Beca...
Article
Full-text available
Background: In the current scenario, designing of world-wide effective malaria vaccine against Plasmodium falciparum remain challenging despite the significant progress has been made in last few decades. Conventional vaccinology (isolate, inactivate and inject) approaches are time consuming, laborious and expensive; therefore, the use of computati...
Chapter
Full-text available
Currently, the targeted drug delivery system that has a pivotal role in the future of personalized medicines has gained significant attention toward research as well as commercial ventures. Targeted drug delivery systems, which are also made up of nanoscale drug carrier molecules, are designed for improving the communication of cellular as well as...
Chapter
Full-text available
MicroRNAs (miRNA) are small noncoding oligoribonucleotides having potential of silencing/knocking out target genes by regulating posttranscriptional events of gene expression. Since many miRNAs have exhibited change in profile in disease conditions, researchers are attracted toward their role assignment in disease development and control, if any. W...
Chapter
Full-text available
Currently, the targeted drug delivery system that has a pivotal role in the future of personalized medicines has gained significant attention toward research as well as commercial ventures. Targeted drug delivery systems, which are also made up of nanoscale drug carrier molecules, are designed for improving the communication of cellular as well as...
Thesis
GABA transamination is an enzymatic reaction that completed by GABA-Transaminase enzyme via GABA shunt pathway, which potentially regulates the metabolism of GABA. GABA shunt pathway is comprises of three important enzymes:- Glutamate decarboxylase (GAD), GABA-transaminase (GABA-T) and succinic semialdehyde dehydrogenase (SSADH). During the senesce...
Chapter
Full-text available
The worldwide increasing environmental issues owing to fossil fuels and their anticipated shortage in near future have fueled the research towards the search and development of alternative fuels from renewable sources. Recently, the biomass-based transport fuels have turn out to be strategic attention for counties with intention to enhance the sust...
Chapter
Full-text available
Microorganisms especially bacteria and cyanobacteria have the ability to synthesize polyhydroxyalkanoates (PHAs) granules as carbon and energy storage compounds within their cells. Owing to eco-friendly, biodegradability, modifiable mechanical properties, non-toxicity, biocompatibility, hydrophobicity, cellular growth support, piezoelectricity, att...
Article
Full-text available
Lignocellulose biorefinery encompasses process engineering and biotechnology tools for the processing of lignocellulosic biomass for the manufacturing of bio-based products (such as biofuels, bio-chemicals, biomaterials). While, lignocellulose biorefinery offers clear value proposition, success at industrial level has not been vibrant for the comme...
Poster
The present study involved synthesis of Nickel nanoparticles (NiNPs) using “bottom-up” approach through biochemical reduction by leaf extract of Cannabis sativa with aqueous solution of hydrated Nickel sulphate heptahydrate (as precursor).
Poster
Nanotechnology deals with the study of materials in the range of nanometers (1-100 nm). The day to day development of nanotechnology creates a major interest in the development and fabrications of different dimensioned nanoparticles. The nanomaterials can be synthesized by different methods involving chemical, physical and biological approaches. Am...
Article
Full-text available
Polyhydroxyalkanoates (PHAs) have received much attention at the current scenario due to their attractive material properties, viz. biodegradability, biocompatibility, thermoplasticity, hydrophobicity, piezoelectricity, and stereospecificity. All these properties make them highly competitive for various industrial applications similar to non-degrad...
Book
Full-text available
Pseudomonas aeruginosa MTCC 7925, a sludge isolate, was found to accumulate a novel short-chain-length-long-chain-length (SCL-LCL) co-polymer composed of 3-hydroxybutyric acid (3HB), 3-hydroxyvaleric acid (3HV), 3-hydroxyhexadecanoic acid (3HHD) and 3-hydroxyoctadecanoic acid (3HOD) as components.The co-polymer production was enhanced to 49% on dry...
Article
Full-text available
Growing concerns over conventional plastic materials and their detrimental effects on the environment have paved the way for exploring alternative sources for the production of bioplastics/biodegradable polymers. Polyhydroxyalkanoates (PHAs), being eco-friendly, biodegradable and renewable, with material properties comparable to conventional plasti...
Chapter
Full-text available
PHA polymers have gained substantial interest in recent years as a result of rising environmental concerns over conventional plastics. Despite the basic attractiveness as an alternate for petroleum-derived polymers, the foremost obstacle facing triumphant commercialization of PHAs is the high price of bacterial fermentation, which brought photoauto...
Chapter
Full-text available
Conventional plastics such as polyethylene, polypropylene, polystyrene, poly(vinyl chloride) and poly(ethylene terephthalate) are high molecular weights polymeric materials vary from 50,000 to 1,000,000 Da. They have attained unique position in modern material technology. They are omnipresent in today’s society with range from ordinary to high-tech...
Chapter
Full-text available
Conventional plastics such as polyethylene, polypropylene, polystyrene, poly(vinyl chloride), and poly(ethylene terephthalate) are high-molecular-weight polymeric materials which vary from 50,000 to 1,000,000 Da. They have attained unique position in modern material technology. They are omnipresent in today’s society with range from ordinary to hig...
Article
Full-text available
The last decade has witnessed a tremendous impetus on biofuel research due to the irreversible diminution of fossil fuel reserves for enormous demands of transportation vis-a-vis escalating emissions of green house gasses (GHGs) into the atmosphere. With an imperative need of CO2 reduction and considering the declining status of crude oil, governme...
Poster
Biosynthesis of nanoparticles is considered to be one of the fastest developing research areas. The present study focused on the green synthesis of Zinc oxide quantum dots (ZnO QDs) from Zinc acetate using Eclipta alba leaf extract. UV-Vis absorption spectroscopy was used to monitor the production of zinc oxide nanoparticles in the range of 200-500...
Poster
Nanobiotechnology is emerging as one of the novel area of research in the science and technology that coupled with different viable applications such as cosmetics, pharmaceuticals, environmental, healthcare, food and feed including biomedical sciences. In this study an attempt is made to produce nickel nanoparticles by treating freshly prepared lea...
Poster
Nanobiotechnology is emerging as one of the novel area of research in the science and technology that coupled with different viable applications such as cosmetics, pharmaceuticals, environmental, healthcare, food and feed including biomedical sciences. In this study an attempt is made to produce nickel nanoparticles by treating freshly prepared lea...
Chapter
Full-text available
Modern world is experiencing energy insecurity because of extreme population pressure and depleting energy resources. Fossil fuels though have highly applauded for contributing to today’s development, are non renewable energy and debated for not sustainable. This has posed serious challenges to the scientific fraternity for finding the suitable alt...
Article
Full-text available
Ubiquitous conventional plastics, generally manufactured from finite, non-sustainable fossil fuels are non-biodegradable wonder entities but their ill effect on Mother Nature has subsequently raised major environmental concerns like their safe disposal, solid waste management and several potential hazards. Such concerns have fuelled initiatives for...

Questions

Questions (8)
Question
I just want to know which size range (1-100 nm) of Nickel or other metallic nanoparticles will depict maximum catalytic or antimicrobial activities. Your scientific explanation in the same direction will be highly appreciated.
Question
How to differentiate between the absorption peak of Nickel and Nickel nanoparticles? Which peak will be appeared first (Nickel or Nickel nanoparticles in the absorption spectrum of UV-Vis spectrophotometer?
Question
We will be highly thankful if scientist community help us to enhance the stability of our fabricated nickel nanoparticles using green chemistry approach. Please suggest which type of specific substances will be helpful for increasing the stability of Nickel nanoparticles.
Question
This question is related to the cost-effective production of value added chemicals/ products from lignocellulosic biomass (LCB). LCB is one of the abundant material present on the earth, which is polymer of glucose molecules. The major problem linked with the economical production of value added chemicals from such LCB is the efficient yield of fermentable sugars or unlocking of glucose molecules after suitable pretreatment process. In this context, which pretreatment techniques are most effective and economical for unlocking sugars from LCB?
Question
If I am not wrong, spectrophotometric determination and quantification of polyhydroxyalkanoate (PHA) will be cost-effective and time saving over highly expensive and sophisticated techniques such as GC etc.

Network

Cited By