Question
Asked 25th Mar, 2015

Are there similarities between Neural crest cells & Cancer cells?

Can be considered the neural crest cells is the only somatic cells that contain the ability to migration during the embryonic development ? and is there any type of cancer cells that have the similar ability in it?

Most recent answer

Ricardo Castilho Garcez
Federal University of Santa Catarina
Hello Saleh Alkarim,
The NC cells indeed share many characteristics with the tumor cells but are not the only ones. Epithelial-mesenchymal transition and migration are common features during embryonic development. They are present in gastrulation (epiblast cells), in the formation and differentiation of mesoderm too.

All Answers (4)

I am not sure what you meant by "custom" cells. please explain and I may be able to answer.
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Saleh Alkarim
King Abdulaziz University
Hello
How are you brother Mohammad Asim , I mean " Neural crest cells " This  cells are a band of specialized cells from the neuroectoderm that lies along the outer surface of each side of the neural tube in the early stages of embryonic development. The cells migrate laterally throughout the embryo and give rise to certain spinal, cranial, and sympathetic ganglia. They also influence the ectomesenchyme to form dental tissues.
thank you
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Kulvinder kochar kaur
Dr kulvinder kaur centre for human reproduction,Jalandhar,Punjab,India.
although reD A LOT ABOUT NEURAL CREST cells and its role along with olfactory shealhing cells in Gn RH neuronal migration to understand development of origin of Gn RH cells AND VARIOUS SYNDROMES LKE charge syndrome ASSOCIATED WITH IT dont have any idea regarding cancer stem cells similar to neural crast cells capablwe of similar differentiation.
Ricardo Castilho Garcez
Federal University of Santa Catarina
Hello Saleh Alkarim,
The NC cells indeed share many characteristics with the tumor cells but are not the only ones. Epithelial-mesenchymal transition and migration are common features during embryonic development. They are present in gastrulation (epiblast cells), in the formation and differentiation of mesoderm too.

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