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12j Healed skin grafts 12 months after placement. The loss of a great volume of tissue makes the defect more pronounced though the surrounding soft tissues have healed well despite the life-threatening infection.
Source publication
Dentofacial defects can be small or very large, consisting of defects in the craniomaxillofacial region with missing soft tissue, bony and other hard tissue components. Such combined mucosal, osseous and even cartilaginous defects can be reconstructed using flaps and bone grafts, or hopefully, in the future with bone graft substitutes or even tissu...
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There is an increasing demand for bone graft substitutes that are used as osteoconductive scaffolds in the treatment of bone defects and fractures. Achieving optimal bone regeneration requires initial cell seeding of the scaffolds prior to implantation. In order to achieve an efficient seeding of the scaffolds, a novel cell seeding chamber was deve...
Nowadays, millions of people worldwide are affected by problems of bones and articulations. These conditions represent about a half of the chronic diseases developed in individuals over 50 years, leading to problems of prolonged pain and physical inability, which usually require surgery, where bone grafts or implants are used. Nonetheless, despite...
Recently, techniques have been reported that involve the preparation of extracted teeth from patients used as particulated bone graft materials for bone graft purposes. For implant placement and bone graft, autogenous teeth bone graft materials were used in 15 patients, and clinically excellent results were obtained. In histological examination, fa...
The authors installed implants combined with guided bony regeneration (GBR) using autogenous tooth bone graft material in the patients. In one patient, GBR and simultaneous implant placement were performed. In two patients, GBR was performed and the implants were placed after 6 months. All patients achieved favorable clinical outcomes. Excellent os...
The aim of this study was to histologically evaluate the potential for vertical bone augmentation of the Bio-Oss® graft compared to a blood clot in conjunction with an occlusive barrier in the rabbit calvaria defect model. Metallic dome shaped barriers with 4.5 mm width and 3.5 mm height were positioned in six adult rabbit skulls. At the right side...
Citations
This chapter explores the possible use of stem cells in the context of cleft lip and palate reconstruction. Cleft defects by their very nature are associated with missing tissue, whether it is bone, cartilage, muscle, mucosa, or skin and its adnexal structures. The chapter focuses on the reconstruction of cranio-maxillofacial bones formed by intramembranous ossification, in part to serve as a future stepping stone toward understanding the complex problems faced by long bones in the axial skeleton. To understand bone reconstruction, the surgeon must fully understand bone healing and the healing of the surrounding soft tissues. The chapter discusses the use of allogeneic, alloplastic materials and growth factors. The addition of pluripotent mesenchymal stem cells (MSCs) has the promise of reconstructing larger bone defects with predictable results. Adipose-derived adult MSCs may be useful in future bone regeneration and tissue engineering efforts using autogenous adipose-derived stem cells, growth factors, and resorbable.
