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gNET patients' prognostic curves of different G grade in the same TNM stage. Prognostic curves of gNET patients with different G grade were shown in the 8th AJCC TNM stage I, p < 0.05 (A). Prognostic curves of gNET patients with different G grade were shown in the 8th AJCC TNM stage II. Prognosis of gNET patients (G1 vs. G2; G1 vs. G3) showed statistical difference (p < 0.05), but prognosis of patients (G2 vs. G3) did not (p = 0.266) (B). Prognostic curves of gNET patients with different G grade were shown in the 8th AJCC TNM stage III. Prognosis of gNET patients (G1 vs. G3) showed statistical difference (p < 0.05) (C). Prognostic curves of gNET patients with different G grade were shown in the 8th AJCC TNM stage IV, p < 0.05 (D). gNET, gastric neuroendocrine tumor; TNM, tumor–node–metastasis.

gNET patients' prognostic curves of different G grade in the same TNM stage. Prognostic curves of gNET patients with different G grade were shown in the 8th AJCC TNM stage I, p < 0.05 (A). Prognostic curves of gNET patients with different G grade were shown in the 8th AJCC TNM stage II. Prognosis of gNET patients (G1 vs. G2; G1 vs. G3) showed statistical difference (p < 0.05), but prognosis of patients (G2 vs. G3) did not (p = 0.266) (B). Prognostic curves of gNET patients with different G grade were shown in the 8th AJCC TNM stage III. Prognosis of gNET patients (G1 vs. G3) showed statistical difference (p < 0.05) (C). Prognostic curves of gNET patients with different G grade were shown in the 8th AJCC TNM stage IV, p < 0.05 (D). gNET, gastric neuroendocrine tumor; TNM, tumor–node–metastasis.

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Background: The 8th tumor-node-metastasis (TNM) classification of the American Joint Committee on Cancer (AJCC) can be used to estimate the prognosis of gastric neuroendocrine tumor (gNET) and gastric neuroendocrine carcinoma (gNEC) patients but not gastric neuroendocrine neoplasms (gNENs). Methods: First, in the SEER (training) dataset, a TNMG...