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expressed as deaths prevented relative to FuR. 239

expressed as deaths prevented relative to FuR. 239

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Figure 1: Allocation proportions within the full cohort and within each...
Figure 5: Expected power at each trial stage using subgroup-specific...
expressed as deaths prevented relative to FuR. 239
Should RECOVERY have used Response Adaptive Randomization? Evidence from a simulation study
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  • Aug 2021
Background The Randomised Evaluation of COVID-19 Therapy (RECOVERY) trial is aimed at addressing the urgent need to find effective treatments for patients hospitalised with suspected or confirmed COVID-19. The trial has had many successes, including discovering that dexamethasone is effective at reducing COVID-19 mortality, the first treatment to r...
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High-Dose Dexamethasone Versus Tocilizumab in Moderate to Severe COVID-19 Pneumonia: A Randomized Controlled Trial
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Background and objectives: Recent randomized controlled trials (RCTs) have indicated potential therapeutic benefits with high-dose dexamethasone (HDD) or tocilizumab (TCZ) plus standard care in moderate to severe coronavirus disease2019 (COVID-19) with acute respiratory distress syndrome (ARDS). No study has compared these two against each other. W...
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