Figure 8 - available via license: Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International
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a, b. c. HDSF cells 45 passage, 52 days after re-seeding. Different zones of the same flask. The average density of the culture is 18000 cell / cm 2 .
Source publication
The article describes effects of telomerization on proliferative activity in cultured cutaneous diploid fibroblasts obtained from an adult men aged 57 years. It is shown that the cells in the control culture initially divide quite actively, but starting from the 27th to the 40th passages, the rate of their division decreases and the time to reach t...
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The proliferative capacity and continuous survival of cells are highly dependent on telomerase expression and the maintenance of telomere length. For this reason, elevated expression of telomerase has been identified in virtually all cancers, including leukemias; however, it should be noted that expression of telomerase is sometimes observed later...
