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a, b Medial (a) and lateral (b) schematic representations of a right hemisphere. The morphology and trajectory of the fibers of the CTT are illustrated. The rostral, middle, and caudal segments of the tract are highlighted in red, yellow, and orange color, respectively, and superimposed on a schematic drawing of the hemisphere. The diamonds, circles, squares, and triangles represent the areas of cortical termination of the corticotegmental fibers in Brodmann’s areas 1/2/3(somatosensory cortex), 4, 6, and 8, respectively. c Schematic representation of an axial cut of a cerebral hemisphere at the level of the basal ganglia, thalamus, and internal capsule. The topography of the CTT with respect to the adjacent fiber tracts is illustrated. The segments of the internal capsule (i.e., anterior limb, genu, posterior limb, retrolenticular part) are exhibited. The corticotegmental fibers, corticospinal fibers, thalamic radiations, and frontocaudate fibers are highlighted in red, cyan, green, and dark blue color, respectively. CTT mainly travels in the genu, posterior limb, and retrolenticular part of the internal capsule medial to the fibers of the corticospinal tract while the thalamic radiations and frontocaudate fibers extend to the anterior limb of the internal capsule. CN caudate nucleus, CTT corticotegmental tract, LN lentiform nucleus, TH thalamus

a, b Medial (a) and lateral (b) schematic representations of a right hemisphere. The morphology and trajectory of the fibers of the CTT are illustrated. The rostral, middle, and caudal segments of the tract are highlighted in red, yellow, and orange color, respectively, and superimposed on a schematic drawing of the hemisphere. The diamonds, circles, squares, and triangles represent the areas of cortical termination of the corticotegmental fibers in Brodmann’s areas 1/2/3(somatosensory cortex), 4, 6, and 8, respectively. c Schematic representation of an axial cut of a cerebral hemisphere at the level of the basal ganglia, thalamus, and internal capsule. The topography of the CTT with respect to the adjacent fiber tracts is illustrated. The segments of the internal capsule (i.e., anterior limb, genu, posterior limb, retrolenticular part) are exhibited. The corticotegmental fibers, corticospinal fibers, thalamic radiations, and frontocaudate fibers are highlighted in red, cyan, green, and dark blue color, respectively. CTT mainly travels in the genu, posterior limb, and retrolenticular part of the internal capsule medial to the fibers of the corticospinal tract while the thalamic radiations and frontocaudate fibers extend to the anterior limb of the internal capsule. CN caudate nucleus, CTT corticotegmental tract, LN lentiform nucleus, TH thalamus

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This study opts to investigate the thus far ill-defined intra-hemispheric topography, morphology, and connectivity of the extra- pyramidal fibers that originate from the frontoparietal cortex and project to the tegmental area and to explore structural correla- tions to the pyramidal pathway. To this end, twenty normal adult, formalin-fixed cerebral...

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