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Introduction:
Cutaneous angiosarcoma is an uncommon aggressive tumor known to arise in chronic lymphedema of various etiologies with post mastectomy lymphedema being the most common cause also known as Stewart-Treves syndrome. Chronic filarial lymphedema is the most uncommon etiology for development of angiosarcoma.
Case report:
We describe two...
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Context 1
... 61-year-old female presented with an enlarged and edematous right leg (Fig. 1). The patient reported a history of lymphatic filariasis diagnosed 15 years previously. She complained of rapidly increasing skin nodules over her leg progressing upward for 6 months. Her prior treatment consisted of antibiotics with variable response. On examination, there was extensive skin thickening with multiple nodules and an ...
Context 2
... amputation was planned (Fig. 8), maintaining a 2 cm margin. Postoperative pathology confirmed angiosarcoma, expressing CD31 and CD34 and D2-40 ( Fig. 9). The patient received doxorubicin-paclitaxel based adjuvant chemotherapy. At 6 months, patient had blisters on the stump and had to undergo re-fitting of the prosthesis. At 12 month follow-up (Fig. 10), the patient is disease-free as confirmed with PET scan. He is currently ambulant without any ...
Context 3
... 61-year-old female presented with an enlarged and edematous right leg (Fig. 1). The patient reported a history of lymphatic filariasis diagnosed 15 years previously. She complained of rapidly increasing skin nodules over her leg progressing upward for 6 months. Her prior treatment consisted of antibiotics with variable response. On examination, there was extensive skin thickening with multiple nodules and an ...
Context 4
... amputation was planned (Fig. 8), maintaining a 2 cm margin. Postoperative pathology confirmed angiosarcoma, expressing CD31 and CD34 and D2-40 ( Fig. 9). The patient received doxorubicin-paclitaxel based adjuvant chemotherapy. At 6 months, patient had blisters on the stump and had to undergo re-fitting of the prosthesis. At 12 month follow-up (Fig. 10), the patient is disease-free as confirmed with PET scan. He is currently ambulant without any ...
Context 5
... 61-year-old female presented with an enlarged and edematous right leg (Fig. 1). The patient reported a history of lymphatic filariasis diagnosed 15 years previously. She complained of rapidly increasing skin nodules over her leg progressing upward for 6 months. Her prior treatment consisted of antibiotics with variable response. On examination, there was extensive skin thickening with multiple nodules and an ...
Context 6
... amputation was planned (Fig. 8), maintaining a 2 cm margin. Postoperative pathology confirmed angiosarcoma, expressing CD31 and CD34 and D2-40 ( Fig. 9). The patient received doxorubicin-paclitaxel based adjuvant chemotherapy. At 6 months, patient had blisters on the stump and had to undergo re-fitting of the prosthesis. At 12 month follow-up (Fig. 10), the patient is disease-free as confirmed with PET scan. He is currently ambulant without any ...
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Introduction:
Cutaneous angiosarcoma is an uncommon aggressive tumor known to arise in chronic lymphedema of various etiologies with post mastectomy lymphedema being the most common cause also known as Stewart-Treves syndrome. Chronic filarial lymphedema is the most uncommon etiology for development of angiosarcoma.
Case report:
We describe two...