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a and b: CT Chest with bilateral lower lobe nodular lesions (red arrow) and cavitatory lesions in left lower lobe (blue arrow); 2-c: Hyperintense nodular lesion left parietal region (red arrow). 2-d: Multiple focal hyperintense nodular lesions in cerebral, cerebellar hemispheres and brainstem. 2-e: T1 Contrast MRI was showing multiple enhancing nodular lesions (pink arrow) scattered in bilateral cerebral and cerebellar with a ring enhancing lesion (pink arrow) in the left posterior high parietal region.
Source publication
Nocardiosis is an opportunistic infection seen in people with impaired host defenses usually cell mediated immunity. It can involve a single organ or present as disseminated infection affecting multiple organ systems. We are reporting a case of 60 year old; an immunocompetent female presented with fever, cough, skin lesions and altered sensorium. T...
Citations
... Nocardiosis is an infectious disease caused by a grampositive, aerobic bacterium of the order of Actinomycetes; they behave as opportunistic microorganisms and are commonly found in soil, water, and organic matter, with more than 90 species identified and 54 associated with human diseases. 1,2 Infection by Nocardia often occurs in immunocompromised hosts, in particular those with a history of organ transplant, including BMT (Bone Marrow Transplant) and solid organ recipients, in which there is a high risk of mortality in the first year after transplantation. 1,3 The prevalence of nocardiosis is considered rare worldwide, and in Ecuador, it still remains unknown. ...
... 1,2 Infection by Nocardia often occurs in immunocompromised hosts, in particular those with a history of organ transplant, including BMT (Bone Marrow Transplant) and solid organ recipients, in which there is a high risk of mortality in the first year after transplantation. 1,3 The prevalence of nocardiosis is considered rare worldwide, and in Ecuador, it still remains unknown. ...
... 6 To the best of our knowledge, there is a strong association between chronic glucocorticoid therapy and nocardiosis, attributed to the inherent effects in the host's immune mechanisms, mainly decreasing cellular immunity, making patients vulnerable to these infections. 1 This was evidenced in this patient with a 3-year history of AOSD chronically treated with oral corticosteroids (prednisone) and methotrexate, in addition to 2 cycles of etanercept. ...
Cerebral nocardiosis is a rare and opportunistic cerebral infection caused by Nocardia spp., a gram‐positive, aerobic bacteria of the Actinomycetes order. Patients with cell‐mediated immunodeficiencies are often targeted by this microorganism, for which early diagnosis and therapeutic approach are essential. Nocardiosis is a rare bacterial infection that requires applied microbiology laboratory techniques to establish its diagnosis and to provide a targeted treatment.
