Figure - available from: Molecular Cytogenetics
This content is subject to copyright. Terms and conditions apply.
a: Karyogram of the t(Y;15) male patient. The der(15) and X chromosomes are indicated by arrows. b: Ideograms of chromosomes Y, 15, and dic(Y;15). The Y centromere and 15 centromere of the dicentric chromosome are indicated by arrows. c: 46,XY karyogram of the patient's father. d: 46,XX karyogram of the patient's mother
Source publication
Background
A rare disease is that an individual with a non-chimeric karyotype of 45,X develops into a male. We explored the genetic aetiology of an infertile male with an apparent 45,X karyotype, which was subsequently verified as cryptic translocation between chromosomes Y and 15.
Methods
DNA was extracted from the patient's peripheral blood. A r...
