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a Histopathologically, proliferating adenocarcinoma cells demonstrated conjoined tubular structures. On immunohistochemical analysis, the tumor cells were positive for CK7 (b) and negative for CK20 (c) and showed a Ki-67 labeling index of less than 3% (d)
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Background:
Late recurrence of gastric cancer at 10 years post-gastrectomy is extremely rare, and the underlying mechanism remains unclear. We report a para-aortic lymph node metastasis case that recurred 12 years postoperatively.
Case presentation:
A 44-year-old woman pathologically diagnosed with moderately to poorly differentiated adenocarcin...
Context in source publication
Context 1
... and tumor marker levels also decreased (CEA: 1.1 ng/mL, CA19-9: 20.3 U/mL). Para-aortic nodal dissection (PAND) of No. 16b1lat and int stations was performed. In the dissected lymph nodes, proliferating adenocarcinoma cells demonstrating conjoined tubular structures were observed, a finding consistent with that of gastric cancer metastasis (Fig. 4a). Scar-like fibrosis and aggregation of foamy histiocytes were observed around the adenocarcinoma cells, indicating that a part of the tumor had undergone necrosis following chemotherapy. The immunohistochemical staining showed that CK7 was expressed in primary and recurrent specimens (Figs. 1c, 4b). Immunohistochemical staining for ...
