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a Coronal T1 fat-sat with contrast showing a voluminous partial exophytic lesion and heterogeneous aspect in hepatic segments II and III (arrow). b Axial T1 with fat saturation evidencing focus of high signal (arrow) compatible with the blood component inside the lesion. c Axial T1 in-phase showing the lesion in the left lobe with peripheral intermediate signal and central hypersignal area due to the presence of a blood component (arrows). d Axial T1 out-phase showing a significant decrease of the signal of the solid part of the lesion, indicating a predominant adipose composition (arrow).
Source publication
Hepatocellular adenomas (HCAs) are rare benign monoclonal hepatic tumors that commonly occur in females (3–4 per 100,000 women) due to the use of oral contraceptives, its primary risk factor. Recently, HCAs have been classified into 4 distinct subtypes according to genotypic and phenotypic characteristics and clinical features: inflammatory HCA (40...
Context in source publication
Context 1
... geneous expansive nodular lesion in the left liver lobe, partially exophytic, located at the periphery of segments II/III, measuring around 10.3 × 6.8 × 10.7 cm. The nodular lesion was visualized in the contrast medium without "wash-out," noting a significant signal drop in the out-phase sequence, indicating a massive fat component of the lesion (Fig. 1). These findings are strongly indicative of HNF1A adenoma. However, an intralesional blood component was identified, which was characterized by a high spontaneous signal in the T1 fat-sat sequence, with bleeding being extremely uncommon in the subtype described but more commonly associated with IHCA. Her liver function tests, aspartate ...
Similar publications
Hepatocellular adenoma (HCA) is a rare benign liver tumour associated with the use of oral contraceptives or other steroid medications which occurs predominantly in young and middle-aged women. Unlike other benign liver tumours, an HCA may be complicated by bleeding and malignant transformation. HCAs have been divided into four subtypes based on mo...
Introduction and importance.
Hepatocellular adenoma (HCA) is a rare liver tumor. We report a case of a radio-resistant liver tumor that was removed surgically and found to be HCA.
Case presentation.
A 37-year-old Japanese man was incidentally diagnosed with a liver tumor. He had no history of viral hepatitis nor metabolic disorders. MRI revealed a...
Background
Hepatocellular adenomas (HCA) are benign liver tumors at risk of hemorrhage. The influence of pregnancy on HCA growth and potential bleeding remains unclear. This study investigates HCA-associated behavior and bleeding complications during or shortly after pregnancy.
Methods
(I) Single center retrospective cohort study of HCA during and...
Abstract Background To investigate whether fractal analysis of perfusion differentiates hepatocellular adenoma (HCA) subtypes and hepatocellular carcinoma (HCC) in non-cirrhotic liver by quantifying perfusion chaos using four-dimensional dynamic contrast-enhanced magnetic resonance imaging (4D-DCE-MRI). Results A retrospective population of 63 pati...
Citations
... As in our case, non-specific abdominal pain constituted a revealing circumstance [5]. Elsewhere, clinical manifestations varied from the absence of clinical signs in 50% cases to acute symptoms due to tumor rupture or bleeding [5,6]. ...
Unclassified hepatic hepatocellular adenoma in men is still a challenging entity regarding clinical manifestations, diagnosis, and treatment as in our case. It still need more investigations determining their characteristics, risk of complications and malignant transformation in order to improve their therapeutic care.
