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Aqueous extract of Clinacanthus nutans leaves were used as a biological source for the reduction of
silver nitrate into silver nanoparticles. Result obtained from UV-Visible analysis exhibit the absorption
peak at 460 nm confirms the production of silver nanoparticles. FTIR analysis showed the presence of
alkyne, alcohol and primary amine that are...
Citations
... Furthermore, nanoparticles affect membranes (membrane proteins) and cause bacterial cell death. Similarly, surface imperfections in the symmetry of nanoparticles cause bacterial inhibition and cell damage [23], [24]. ...
Physical Sciences book series aims to bring together leading academic scientists, researchers and research scholars to exchange and share their experiences and research results on all aspects of Physical Sciences. The field of advanced physical sciences has not only helped the development in various fields in Science and Technology but also contributes the improvement of the quality of human life to a great extent. The focus of the book would be on state-of-the-art technologies and advances in Physical Sciences. It also focuses on a range of issues but not limited to
... P. Kowshihan et al has stated that after preparing coriander oleoresin mediated silver nanoparticles and confirmed by using UV-Visible spectroscopy, it was evaluated for its antifungal and antibacterial properties against S. mutans, Lactobacillus, S. aureus and C. albicans. It was seen that coriander oleoresin mediated silver nanoparticles had a good antimicrobial effect and can be used against the above mentioned infections [14]. ...
Aim: The main aim of present study was to assess the cytotoxic effect of coriander oleoresin against lung cancer cell line A549. Introduction: Coriandrum sativum (Coriander), family Umbelliferae. Coriander contains mainly essential oil and has antioxidant, diuretic, anti-diabetic anticonvulsant, hypnotic sedative, anti-mutagenic, antimicrobial, anthelmintic activity. Materials and Methods: Coriander oleoresin (product number: 4010000243) was obtained from Synthite Industries Private Limited, Kerala. In the present study, lung cancer cell line A549 was treated with coriander oleoresin at different concentrations and later evaluated for its cytotoxic activity using MTT assay. Results: The cytotoxic effect of coriander oleoresin on lung cancer cell line was proved; the drug concentration increased, the percentage of cell viability decreased proving its cytotoxic effect. The coriander oleoresin has shown a dose dependent cytotoxic effect on lung cancer cell lines. As the drug concentration increased, the percentage of cell viability decreased proving its cytotoxic effect. The IC50 value was 80 μg/ml. Conclusion: In the present study, coriander oleoresin showed a good cytotoxic effect on lung cancer cell lines which may be helpful in treatment of lung cancer. However more research is needed to understand the underlying mechanisms of the cytotoxicity property of the plants.
