Zonal prostate anatomy on axial T2-weighted MRI image: peripheral zone (PZ) and transitional zone (TZ) are well depicted. Anterior fibromuscular stroma (FMS) and peri-urethral tissue (PUT) are also well detected.

Contexts in source publication

Context 1

... date, prostate MRI is a multiparametric technique thanks to the introduction of functional sequences like diffusion weighted imaging (DWI) and its derivative apparent diffusion coefficient (ADC) maps, and dynamic contrast enhanced (DCE) sequences. Multiparametric MRI not only allows anatomical information [like zonal anatomy (Figure 1) but also provided capability to distinguish benign pathological tissue and clinically insignificant prostate cancer from significant cancer. ...

Context 2

... p<0.001; Kapp-ratio rho=0.662, p<0.001) and ADC-ratio values (Kapp rho=0.656 p<0.001; Kapp-ratio rho=0.722, p<0.001). The correlation between Kapp and ADC is illustrated in Figure 4. Gleason score demonstrated a significant negative correlation with Kapp (rho=-0.392, p=0.022), ADCratio (rho=-0.400, p=0.019) and Kapp-ratio (rho=-0.369, p=0.032). (rho=0.666, p<0.001). Table 4. Area under the receiver operating characteristic curve (AUROC), 95% confidence interval (95% CI), sensitivity (Se) and specificity (Sp) and cut-off values based on the Youden index of apparent diffusion coefficient (ADC) and apparent kurtosis coefficient (Kapp) for the diagnosis of GS ≥6 and ≥7 prostate cancers, respectively. ...