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Source publication
There are three bone graft methods for bone defects caused by diseases such as cancer and accident injuries: Autogenous bone grafts, Allografts and Artificial bone grafts. In this study, meshed GUM Metal plates with lower elasticity, high strength and high biocompatibility are introduced to solve the over stiffness & weight problems of ready-used m...
Context in source publication
Context 1
... mechanical properties of meshed plate implants should be close to the mechanical properties of human's cortical bones to minimize damages on patients. Natural cortical bones as shown in figure 2 have volume density range from 0.5 to 1.1 g/cm 3 and elastic modulus range from 2.0 to 30.0 GPa. On the other hand, analytical approaches on bending stiffness of meshed GUM Metal plate specimen are also carried out through finite element method and comparison with experimental results are used to validate analytical method proposed in this study. ...
Citations
There is increasing interest in the development of bone repair materials for biomedical applications. Magnesium (Mg)-based alloys have a natural ability to biodegrade because they corrode in aqueous media; they are thus promising materials for orthopaedic device applications in that the need for a secondary surgical operation to remove the implant can be eliminated. Notably, Mg has superior biocompatibility because Mg is found in the human body in abundance. Moreover, Mg alloys have a low elastic modulus, close to that of natural bone, which limits stress shielding. However, there are still some challenges for Mg-based fracture fixation. The degradation of Mg alloys in biological fluids can be too rapid, resulting in a loss of mechanical integrity before complete healing of the bone fracture. In order to achieve an appropriate combination of bio-corrosion and mechanical performance, the microstructure needs to be tailored properly by appropriate alloy design, as well as the use of strengthening processes and manufacturing techniques. This review covers the evolution, current strategies and future perspectives of Mg-based orthopaedic implants.
