Figure - available from: Journal of Oral Medicine and Oral Surgery
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White lichenoid striations with background erythema involving the left buccal mucosa consistent with oral lichen planus (mild dysplasia on histology) (image provided by Guy's and St Thomas').
Source publication
Introduction: The diagnosis of and risks associated with oral potentially malignant disorders (OPMD) have been widely reported, but little has been published on the management of OPMDs in a primary dental care setting. Hospital services face ongoing pressures due to long-term follow-up, with a need for surveillance to be jointly undertaken with pri...
Citations
... Among OPMDs, PVL is associated with the highest incidence of oral cancer. 15 16 A recent systematic review found that overall malignant transformation occurs in 49.5% (CI 26.7% to 72.4%) of PVL cases. 2 16 The progression of PVL to VC could not be associated with the traditional risk factors, and it commonly affects older females. 3 The reported HPV prevalence in PVL may range from 0% to 88%, and the putative role of human papillomavirus (HPV) is Case report still controversial. ...
Proliferative verrucous leukoplakia (PVL) is a distinct progressive and multi-focal form of oral leukoplakia, not associated with the traditional risk factors (ie, tobacco and alcohol consumption). The incidence of oral squamous cell carcinoma in PVL patients is high. Here, we describe the case of a patient affected by PVL, who developed two metachronous oral verrucous carcinomas at different sites of the oral mucosa. Owing to the high risk of multiple oral squamous cell carcinoma, periodical clinical and histopathological follow-up is mandatory and should continue lifelong.
... Il termine leucoplachia viene utilizzato per descrivere una lesione di colore prevalentemente bianco, non asportabile e non riferibile ad altre condizioni che non comportino un aumentato rischio di sviluppare cancro orale [12] . La leucoplachia rientra infatti nei disordini potenzialmente maligni e presenta un tasso di trasformazione maligna variabile che si attesta intorno al 3% per le lesioni omogenee (uniformemente bianche, con margini ben definiti e con superficie regolare) e al 14,5% per quelle non omogenee (colore bianco e rosso, superficie nodulare/verrucosa, margini poco definiti) [13,14] . [16] . ...
... Gli odontoiatri e gli igienisti dentali visitano quotidianamente pazienti che potrebbero essere potenzialmente affetti da OPMD e, per questo motivo, risulta di fondamentale importanza aumentare la consapevolezza e la conoscenza di questi disturbi tra gli operatori sanitari in ambito odontoiatrico [5] . ...
... Oral potentially malignant disorders (OPMDs) are a group of conditions associated with an increased risk of developing OSCC. Dental practitioners encounter patients presenting with OPMDs, highlighting the importance of increasing awareness and knowledge of these disorders amongst healthcare professionals [4]. ...
