Western blot analysis detecting the phosphorylation of epidermal growth factor receptor (EGFR) at tyrosine (Tyr) residue 845, 1045, and 1068 and the total form of EGFR in the cell lysates upon different treatments (DMSO, PC, EGF, or the combination of PC and EGF) at various time points. β-actin was used as a loading control.

Western blot analysis detecting the phosphorylation of epidermal growth factor receptor (EGFR) at tyrosine (Tyr) residue 845, 1045, and 1068 and the total form of EGFR in the cell lysates upon different treatments (DMSO, PC, EGF, or the combination of PC and EGF) at various time points. β-actin was used as a loading control.

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Re-epithelialization is delayed in aged skin due to a slow rate of keratinocyte proliferation, and this may cause complications. Thus, there has been development of new therapies that increase treatment efficacy for skin wounds. Epidermal growth factor (EGF) has been clinically used, but this agent is expensive, and its activity is less stable. The...