Water deprivation test interpretation (mOsm/Kg)

Water deprivation test interpretation (mOsm/Kg)

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Context 1
... the fact that the patient was presenting with hypernatremia (Table 1) and not hypotonic polyuria, is a strong argument in favor of diabetes insipidus. To address the differential diagnosis, a modified water deprivation test 2 was performed with subsequent administration of 1-desamino-8 -D -arginine vasopressin (DDAVP) ( Figure 2 and Table 2). ...
Context 2
... findings rule out primary polydipsia. DDAVP was administered after 6h:15min, but the patient continued to lose weight and failed to significantly increase urine osmolality, once again remaining below 300 mOsm/Kg and establishing renal insensitivity to DDAVP as the cause of polyuria ( Figure 2 and Table 2). ...

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