Virus titers (log TCID50/mL) before and after a 5 min exposure to FA is shown for Echo-11 (square symbols), HIV-1 (triangles), AdV-5 (circles), and SARS-CoV-2 (inverted triangle). Independent triplicate experiments (duplicates for SARS-CoV-2) are shown.

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Stability of the HIV Reverse Transcriptase enzyme (HIV-1, (A)), of...

Virus titers (log TCID50/mL) before and after a 5 min exposure to FA is...

Virus inactivation by lysis buffers. For each of the viruses and...

Assessment of the possible influence of the agent-removal column and...

Virus Inactivation by Formaldehyde and Common Lysis Buffers

Article

Full-text available

Aug 2023

Ulrike Seeburg
Lorena Urda
Fabian Otte
[...]
Thomas Klimkait

Numerous mammalian viruses are routinely analyzed in clinical diagnostic laboratories around the globe or serve as indispensable model systems in viral research. Potentially infectious viral entities are handled as blood, biopsies, or cell and tissue culture samples. Countless protocols describe methods for virus fixation and inactivation, yet for...